1. Targeting Hypertension to Manage Alzheimer’s Disease: Rational and Promise
- Author
-
Merkulova-Rainon T, Pasteur-Rousseau A, Levy Bi, Kubis N, and Cifuentes D
- Subjects
0301 basic medicine ,medicine.medical_specialty ,business.industry ,Disease ,medicine.disease ,Bioinformatics ,03 medical and health sciences ,Experimental animal ,030104 developmental biology ,0302 clinical medicine ,Epidemiology ,medicine ,Alzheimer's disease ,Risk factor ,Cognitive impairment ,business ,Stroke ,030217 neurology & neurosurgery - Abstract
Epidemiological, clinical and experimental animal studies uncover the close and complex interaction between Alzheimer’s disease and hypertension, a major risk factor for cardiovascular disease and stroke. Here we overview recent evidences on the impacts of both conditions on cerebral vasculature and discuss the ways in which hypertension may contribute to the onset and progression of Alzheimer’s disease.
- Published
- 2016