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Background and Aims: Stachys L. species, which are members of the Lamiaceae family, have long been applied for their therapeutic benefits especially to cure cough, infection, genital tumors, ulcers, inflammatory illnesses, and wounds in Anatolian traditional medicine. In the current study, various extracts prepared from the aerial parts of Stachys cretica subsp. butgarica Rech.f. (SC), Stachys byzantina K. Koch (SB), Stachys thirkei K. Koch and were tested for their in vitro antioxidant, antibacterial, and anticandidat properties. Methods: The aerial parts of three Stachys species were sequentially extracted using n-hexane, chloroform, and methanol. Aqueous extracts of each sample was also prepared by infusion process. The total phenolic content of each extract was determined and the contribution of the biological activities in the samples was evaluated. To assess the antioxidant capacity, samples were studied using CUPRAC activity, DPPH center dot free radical scavenging, and FRAP methods. The antimicrobial activity of the extracts was tested against 7 bacteria and 3 yeast. Results: The infusion and methanol extract exhibited the strongest antioxidant potential and also had the highest percentage of phenolics among the studied extracts. The n-hexane extracts of all studied species showed considerable antifungal activity with MIC values ranging from 312.5-78.12 mg/L. Conclusion: According to our results, three Stachys species were found to be beneficial for their antioxidant and antimicrobial properties. Background and Aims: Stachys L. species, which are members of the Lamiaceae family, have long been applied for their therapeutic benefits especially to cure cough, infection, genital tumors, ulcers, inflammatory illnesses, and wounds in Anatolian traditional medicine. In the current study, various extracts prepared from the aerial parts of Stachys cretica subsp. butgarica Rech.f. (SC), Stachys byzantina K. Koch (SB), Stachys thirkei K. Koch and were tested for their in vitro antioxidant, antibacterial, and anticandidat properties. Methods: The aerial parts of three Stachys species were sequentially extracted using n-hexane, chloroform, and methanol. Aqueous extracts of each sample was also prepared by infusion process. The total phenolic content of each extract was determined and the contribution of the biological activities in the samples was evaluated. To assess the antioxidant capacity, samples were studied using CUPRAC activity, DPPH center dot free radical scavenging, and FRAP methods. The antimicrobial activity of the extracts was tested against 7 bacteria and 3 yeast. Results: The infusion and methanol extract exhibited the strongest antioxidant potential and also had the highest percentage of phenolics among the studied extracts. The n-hexane extracts of all studied species showed considerable antifungal activity with MIC values ranging from 312.5-78.12 mg/L. Conclusion: According to our results, three Stachys species were found to be beneficial for their antioxidant and antimicrobial properties. WOS:000744167900009

SciVal Topics Metrics Abstract Lamiaceae is one of the largest families in the plant kingdom, including the genus Stachys and Scutellaria, which are used in many folk medicines throughout the world for the prevention and also the treatment of several disorders. In vitro biological potential of Stachys iberica subsp. stenostachya and Scutellaria orientalis subsp. sosnowskyi were investigated in the current study. The aerial parts of the plants were extracted using different solvents such as n-hexane, chloroform, and methanol. In addition, infusions of each plant were prepared. The antioxidant potential of the samples was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), ABTS assays, ferrous ion-chelating, and ferric reducing antioxidant power (FRAP) assays. Anticholinesterase activity of the extracts was also determined. Spectrophotometric analysis was used to assess the total phenolic content of the samples. The antimicrobial activities of samples were determined by minimal inhibitory concentration (MIC) against seven bacteria and three Candida spp. yeast. According to the findings, the infusion demonstrated significant antioxidant properties, whilst the extracts demonstrated high-to-moderate antioxidant effects. The n-hexane extracts showed higher antifungal activity against C.parapsilosis and C.tropicalis. These outcomes suggest that these two species from Turkey could be employed in the manufacture of phytopharmaceuticals. 2-s2.0-85120816133