62 results on '"Manickam, Sivakumar"'
Search Results
2. Isolation of protein from Chlorella sorokiniana CY1 using liquid biphasic flotation assisted with sonication through sugaring-out effect
- Author
-
Kit Wayne Chew, Tau Chuan Ling, Shir Reen Chia, Yang Tao, Pau Loke Show, and Manickam Sivakumar
- Subjects
chemistry.chemical_classification ,Chlorella sorokiniana ,Chromatography ,chemistry ,Bioenergy ,Sonication ,Yield (chemistry) ,Protein purification ,Extraction (chemistry) ,Monosaccharide ,Oceanography ,Sugar ,Water Science and Technology - Abstract
Microalgae, a sustainable source of multi beneficial components has been discovered and could be utilised in pharmaceutical, bioenergy and food applications. This study aims to investigate the sugaring-out effect on the recovery of protein from wet green microalga, Chlorella sorokiniana CY1 which was assisted with sonication. A comparison of monosaccharides and disaccharides as one of the phase-forming constituents shows that the monosaccharides, glucose was the most suitable sugar in forming the phases with acetonitrile to enhance the production of protein (52% of protein). The protein productivity of microalgae was found to be significantly influenced by the volume ratio of both phases, as the yield of protein increased to 77%. The interval time between the sonication as well as the sonication modes were influencing the protein productivity as well. The optimum protein productivity was obtained with 10 s of resting time in between sonication. Pulse mode of sonication was suitable to break down the cell wall of microalgae compared to continuous mode as a lower protein yield was obtained with the application of continuous mode. The optimum condition for protein extraction were found as followed: 200 g/L glucose as bottom phase with volume ratio of 1:1.25, 10 s of resting time for ultrasonication, 5 s of ultrasonication in pulse mode and 0.25 g of biomass weight. The high yield of protein about 81% could be obtained from microalgae which demonstrates the potential of this source and expected to play an important role in the future.
- Published
- 2019
3. Current overview of encapsulation
- Author
-
Shirish H. Sonawane, Manickam Sivakumar, Bharat A. Bhanvase, and Shital B. Potdar
- Subjects
Materials science ,Carrier material ,Chemical engineering ,Biological property ,Shell (structure) ,Encapsulation (networking) - Abstract
Encapsulation is the process of stabilization of active compounds through the structuring of systems capable of preserving their chemical, physical, and biological properties, x their release or delivery under established or desired conditions In the process of encapsulation, either one or the mixture of bioactive material is coated with another single material or combination of materials. In encapsulation, two main terminologies are frequently used. One is the material that is being coated is termed active material or core material, and the other is the shell material that is also termed carrier material (shell). The shell material can be in solid, liquid droplets, and gas bubbles to encapsulate liquid or gas inside as a core. The core and shell structure can be in various shapes such as the sphere, microcapsules, microbeads, monocore, multicore, matrix, and multishell.
- Published
- 2020
4. List of contributors
- Author
-
Uday Bagale, Divya P. Barai, Shrikant S. Barkade, Bharat A. Bhanvase, Mayuri Bhatia, Bhaskar Birru, Pallab Kumar Borah, Jitendra Carpenter, Raj Kumar Duary, Vikash Kumar Dubey, Suja George, Shailesh A. Ghodke, M. Clara Gonçalves, Sarang P. Gumfekar, Kalpana Joshi, Irina Kalinina, Trupti Khatal, Vividha K. Landge, Joana C. Matos, Vinod Mokale, D.N. Mokat, Shivraj Naik, Sreenivasa Rao Parcha, Laura C.J. Pereira, Dipak Pinjari, Shital B. Potdar, Irina Potoroko, Ashish P. Pradhane, Gundappa Saha, Virendra Kumar Saharan, Santanu Sasidharan, Prakash Saudagar, P. Shalini, Manickam Sivakumar, Shirish H. Sonawane, Shriram S. Sonawane, Y.C. Suryawanshi, Parag Thakur, S.D. Torawane, and João Carlos Waerenborgh
- Published
- 2020
5. Facile sonochemical synthesis of Ag
- Author
-
Jayachandrabal, Balachandramohan, Thirugnanasambandam, Sivasankar, and Manickam, Sivakumar
- Abstract
Silver Oxide (Ag
- Published
- 2019
6. Facile sonochemical synthesis of Ag2O-guar gum nanocomposite as a visible light photocatalyst for the organic transformation reactions
- Author
-
Thirugnanasambandam Sivasankar, Jayachandrabal Balachandramohan, and Manickam Sivakumar
- Subjects
021110 strategic, defence & security studies ,Environmental Engineering ,Materials science ,Guar gum ,Nanocomposite ,Diffuse reflectance infrared fourier transform ,Health, Toxicology and Mutagenesis ,0211 other engineering and technologies ,02 engineering and technology ,010501 environmental sciences ,01 natural sciences ,Pollution ,Sodium borohydride ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,Benzyl alcohol ,Photocatalysis ,Environmental Chemistry ,Fourier transform infrared spectroscopy ,Waste Management and Disposal ,Silver oxide ,0105 earth and related environmental sciences - Abstract
Silver Oxide (Ag2O)-Guar gum nanocomposite was fabricated via a simple sonochemical co-precipitation method. The obtained photocatalyst was characterized with various techniques such as X-ray diffraction, thermogravimetric analysis, Fourier transform infrared spectroscopy, UV–vis diffuse reflectance spectroscopy, photoluminescence spectroscopy, scanning electron microscopy and transmission electron microscopy along with energy dispersion X-ray spectroscopy. The findings have demonstrated that Ag2O nanoparticles are spherical of 5−20 nm and were dispersed on the surface of polysaccharide guar gum to form Ag2O-guar gum nanocomposite. The as-synthesized nanocomposite was enacted as a competent photocatalyst for the reduction of nitrobenzene and oxidation of benzyl alchohol. The conversion efficiency for the reduction of nitrobenzene was 96 % with the addition of sodium borohydride, and the conversion of benzyl alcohol was 98 %. The highly efficient photocatalytic activity was due to the exceedingly dispersed Ag2O-guar gum nanocomposite where effective separation rate of energy driven electron-hole pairs and stronger light absorption occurs. The possible mechanism of the reactions was implicated in understanding the active species involved in the photocatalytic study.
- Published
- 2020
7. Sonochemical degradation of endocrine-disrupting organochlorine pesticide Dicofol: Investigations on the transformation pathways of dechlorination and the influencing operating parameters
- Author
-
Panda Debabrata and Manickam Sivakumar
- Subjects
Environmental Engineering ,Halogenation ,Health, Toxicology and Mutagenesis ,Sonication ,02 engineering and technology ,010501 environmental sciences ,Endocrine Disruptors ,01 natural sciences ,High-performance liquid chromatography ,Gas Chromatography-Mass Spectrometry ,chemistry.chemical_compound ,Environmental Chemistry ,Dicofol ,Ultrasonics ,Pesticides ,0105 earth and related environmental sciences ,Persistent organic pollutant ,Public Health, Environmental and Occupational Health ,Temperature ,General Medicine ,General Chemistry ,Hydrogen Peroxide ,Pesticide ,021001 nanoscience & nanotechnology ,Pollution ,chemistry ,Wastewater ,Environmental chemistry ,Degradation (geology) ,Gas chromatography ,0210 nano-technology - Abstract
Dicofol, an extensively used organochlorine pesticide and a recommended Stockholm convention persistent organic pollutant (POP) candidate is well known for its endocrine disruptive properties. The sonochemical degradation of Dicofol in aqueous media has been investigated using a 20-kHz probe type sonicator with power inputs from 150 to 450 W. The degradation rate was determined as a function of concentration of Dicofol, solution pH, bulk phase temperature, ultrasonic power density and H2O2 addition. At optimum operating conditions, the pseudo-first-order degradation rate constant (k) was determined to be 0.032 min−1 and the extent of degradation was found to be 86% within 60 min of ultrasound treatment. High performance liquid chromatography (HPLC) and Gas chromatography coupled with mass spectroscopy (GC-MS) analysis indicated the presence of degraded products. The obtained results of Dicofol degradation and control experiments in the presence of H2O2 and radical scavenger test suggest thermal decomposition along with radical attack at bubble-vapor interface to be the dominant degradation pathway. Sonochemical treatment is effective and promising for successful removal of harmful pesticides such as Dicofol and superior removal efficiency for other POPs is expected in the near future with the successful implementation of ultrasound-based wastewater treatment.
- Published
- 2017
8. Cavitation technology – A greener processing technique for the generation of pharmaceutical nanoemulsions
- Author
-
Manickam Sivakumar, Siah Ying Tang, and Khang Wei Tan
- Subjects
Drug ,Materials science ,Green Chemistry Technology ,Acoustics and Ultrasonics ,Chemistry, Pharmaceutical ,media_common.quotation_subject ,Organic Chemistry ,Drug release rate ,Nanotechnology ,Inorganic Chemistry ,Drug Delivery Systems ,Cavitation ,Drug delivery ,Emulsion ,Humans ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Emulsions ,Ultrasonics ,Radiology, Nuclear Medicine and imaging ,Nanocarriers ,Emulsion droplet ,media_common - Abstract
Novel nanoemulsion-based drug delivery systems (DDS) have been proposed as alternative and effective approach for the delivery of various types of poorly water-soluble drugs in the last decade. This nanoformulation strategy significantly improves the cell uptake and bioavailability of numerous hydrophobic drugs by increasing their solubility and dissolution rate, maintaining drug concentration within the therapeutic range by controlling the drug release rate, and reducing systemic side effects by targeting to specific disease site, thus offering a better patient compliance. To date, cavitation technology has emerged to be an energy-efficient and promising technique to generate such nanoscale emulsions encapsulating a variety of highly potent pharmaceutical agents that are water-insoluble. The micro-turbulent implosions of cavitation bubbles tear-off primary giant oily emulsion droplets to nano-scale, spontaneously leading to the formation of highly uniform drug contained nanodroplets. A substantial body of recent literatures in the field of nanoemulsions suggests that cavitation is a facile, cost-reducing yet safer generation tool, remarkably highlighting its industrial commercial viability in the development of designing novel nanocarriers or enhancing the properties of existing pharmaceutical products. In this review, the fundamentals of nanoemulsion and the principles involved in their formation are presented. The underlying mechanisms in the generation of pharmaceutical nanoemulsion under acoustic field as well as the advantages of using cavitation compared to the conventional techniques are also highlighted. This review focuses on recent nanoemulsion-based DDS development and how cavitation through ultrasound and hydrodynamic means is useful to generate the pharmaceutical grade nanoemulsions including the complex double or submicron multiple emulsions.
- Published
- 2014
9. Cavitation Technology—Potential Way of Generating Nanomaterials and Nanoemulsions for Wider Technological Applications
- Author
-
Manickam Sivakumar
- Subjects
High energy ,Materials science ,Cavitation ,Industrial scale ,Nanotechnology ,Droplet size ,Processing methods ,Nanomaterials - Abstract
Development of nanomaterials is continuously on the rise owing to their variety of technological applications and thus gets increased attention not only in the academic research but also on an industrial scale. Nanomaterials behave in a different way compared to their counterpart and showing markedly different properties which may be physical, chemical, biological, electronic, etc. Common techniques that are employed in the development of nanomaterials are high energy ball milling, hydrothermal synthesis, co-precipitation, microemulsion, sol-gel processing, etc. Due to the inherent disadvantages existing with these conventional techniques newer processing methods are always have great consideration. In this connection, cavitation induced by ultrasound exhibits many advantages. Not only the nanomaterials are obtained using this technique, even the nanoformulations such as nanoemulsions could be generated using this technology.
- Published
- 2017
10. Understanding, Prospects and Constraints of Emerging Nanotechnology
- Author
-
Manickam Sivakumar
- Subjects
Atomic force microscopy ,Scale (chemistry) ,Societal impact of nanotechnology ,Nanotechnology ,Nanoscopic scale ,Characterization (materials science) - Abstract
Much effort is currently being devoted in Nanotechnology owing to its diverse range of technological applications. Nanotechnology deals with the design, characterization, production and application of structures, devices and systems by controlling their size and shape at nanometre scale. It focuses on manipulating the most basic components of all matter (atoms and molecules) with great precision and exploiting the novel properties or phenomena observed at that length scale as compared to their bulk-scale counterparts. Thus size effects become predominant at the nano scale. Most of the observed effects at this nano scale could be explained by surface and quantum confinement phenomena. It is an emerging interdisciplinary technology and promises significant advances in various technological applications. Nanotechnology is the new industrial revolution as it has the potential to revolutionise various sectors of the society. Still the potential of this technology has not been fully exploited as many questions still remain to be answered. Notwithstanding these advantages, it is a challenge to the government and industries as yet there are no specific regulations for assessing the toxicity or environmental impact of nanoparticles.
- Published
- 2017
11. Impact of osmotic pressure and gelling in the generation of highly stable single core water-in-oil-in-water (W/O/W) nano multiple emulsions of aspirin assisted by two-stage ultrasonic cavitational emulsification
- Author
-
Siah Ying Tang, Billa Nashiru, and Manickam Sivakumar
- Subjects
Coalescence (physics) ,Aqueous solution ,Materials science ,Chromatography ,Aspirin ,Dispersity ,Aqueous two-phase system ,Water ,Surfaces and Interfaces ,General Medicine ,Surface tension ,Colloid and Surface Chemistry ,Chemical engineering ,Osmotic Pressure ,Emulsion ,Nano ,Osmotic pressure ,Emulsions ,Ultrasonics ,Physical and Theoretical Chemistry ,Oils ,Biotechnology - Abstract
The present investigation focuses in investigating the effect of osmotic pressure, gelling on the mean droplet diameter, polydispersity index, droplet size stability of the developed novel Aspirin containing water-in-oil-in-water (W/O/W) nano multiple emulsion. The aspirin-loaded nano multiple emulsion formulation was successfully generated using two-stage ultrasonic cavitational emulsification which had been reported in author's previous study. The osmotic behavior of ultrasonically prepared nano multiple emulsions were also examined with different glucose concentrations both in the inner and outer aqueous phases. In addition, introducing gelatin into the formulation also observed to play an important role in preventing the interdroplet coalescence via the formation of interfacial rigid film. Detailed studies were also made on the possible mechanisms of water migration under osmotic gradient which primarily caused by the permeation of glucose. Besides, the experimental results have shown that the interfacial tension between the two immiscible phases decreases with varying the composition of organic phase. Although the W/O/W emulsion prepared with the inner/outer glucose weight ratio of 1-0.5% (w/w) showed an excellent droplet stability, the formulation containing 0.5% (w/w) glucose in the inner aqueous phase appeared to be the most stable with minimum change in the mean droplet size upon one-week storage period. Based on the optimization, nano multiple emulsion droplets with the mean droplet diameter of around 400 nm were produced using 1.25% (w/w) Span 80 and 0.5% Cremophore EL. Overall, our investigation makes a pathway in proving that the use of ultrasound cavitation is an efficient yet promising approach in the generation of stable and uniform nano multiple emulsions and could be used in the encapsulation of various active pharmaceutical ingredients in the near future.
- Published
- 2013
12. Impact of process parameters in the generation of novel aspirin nanoemulsions – Comparative studies between ultrasound cavitation and microfluidizer
- Author
-
Siah Ying Tang, Manickam Sivakumar, and Parthasarathy Shridharan
- Subjects
Materials science ,Acoustics and Ultrasonics ,Sonication ,Microfluidics ,Nanotechnology ,In Vitro Techniques ,Inorganic Chemistry ,Pressure ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Radiology, Nuclear Medicine and imaging ,Droplet size ,Aspirin ,business.industry ,Organic Chemistry ,Ultrasound ,Ultrasound cavitation ,Nanostructures ,Cavitation ,Scientific method ,Emulsion ,Feasibility Studies ,Emulsions ,Emulsion droplet ,business ,Biomedical engineering - Abstract
In the present investigation, the operating efficiency of a bench-top air-driven microfluidizer has been compared to that of a bench-top high power ultrasound horn in the production of pharmaceutical grade nanoemulsions using aspirin as a model drug. The influence of important process variables as well as the pre-homogenization and drug loading on the resultant mean droplet diameter and size distribution of emulsion droplets was studied in an oil-in-water nanoemulsion incorporated with a model drug aspirin. Results obtained show that both the emulsification methods were capable of producing very fine nanoemulsions containing aspirin with the minimum droplet size ranging from 150 to 170 nm. In case of using the microfluidizer, it has been observed that the size of the emulsion droplets obtained was almost independent of the applied microfluidization pressure (200-600 bar) and the number of passes (up to 10 passes) while the pre-homogenization and drug loading had a marginal effect in increasing the droplet size. Whereas, in the case of ultrasound emulsification, the droplet size was generally decreased with an increase in sonication amplitude (50-70%) and period of sonication but the resultant emulsion was found to be dependent on the pre-homogenization and drug loading. The STEM microscopic observations illustrated that the optimized formulations obtained using ultrasound cavitation technique are comparable to microfluidized emulsions. These comparative results demonstrated that ultrasound cavitation is a relatively energy-efficient yet promising method of pharmaceutical nanoemulsions as compared to microfluidizer although the means used to generate the nanoemulsions are different.
- Published
- 2013
13. Anti-inflammatory and analgesic activity of novel oral aspirin-loaded nanoemulsion and nano multiple emulsion formulations generated using ultrasound cavitation
- Author
-
Parthasarathy Shridharan, Siah Ying Tang, Manickam Sivakumar, and Angela Min Hwei Ng
- Subjects
Male ,Pain Threshold ,Time Factors ,Polymers ,medicine.drug_class ,Chemistry, Pharmaceutical ,Drug Compounding ,Analgesic ,Anti-Inflammatory Agents ,Administration, Oral ,Pain ,Pharmaceutical Science ,Motor Activity ,Pharmacology ,Carrageenan ,Anti-inflammatory ,Rats, Sprague-Dawley ,chemistry.chemical_compound ,Oral administration ,medicine ,Animals ,Edema ,Nanotechnology ,Technology, Pharmaceutical ,Ultrasonics ,Acetic Acid ,Analgesics ,Drug Carriers ,Aspirin ,Behavior, Animal ,Dose-Response Relationship, Drug ,Rats ,Disease Models, Animal ,chemistry ,Anesthesia ,Emulsion ,Nanoparticles ,Emulsions ,Nanocarriers ,Drug carrier ,medicine.drug - Abstract
The present study investigated the anti-inflammatory and analgesic activities of novel aspirin oil-in-water (O/W) nanoemulsion and water-in-oil-in-water (W/O/W) nano multiple emulsion formulations generated using ultrasound cavitation techniques. The anti-inflammatory activities of nanoemulsion and nano multiple emulsion were determined using the λ-carrageenan-induced paw edema model. The analgesic activities of both nanoformulations were determined using acetic acid-induced writhing response and hot plate assay. For comparison, the effect of pretreatment with blank nanoemulsion and reference aspirin suspension were also studied for their anti-inflammatory and antinociceptive activities. The results showed that oral administration of nanoemulsion and nano multiple emulsion containing aspirin (60 mg/kg) significantly reduced paw edema induced by λ-carrageenan injection. Both nanoformulations decreased the number of abdominal constriction in acetic acid-induced writhing model. Pretreatment with nanoformulations led to a significant increase in reaction time in hot plate assay. Nanoemulsion demonstrated an enhanced anti-inflammatory and analgesic effects compared to reference suspension while nano multiple emulsion exhibited a mild inhibitory effects in the three experimental animal model tests. The results obtained for nano multiple emulsion were relatively lower than reference. However, administration of blank nanoemulsion did not alter the nociceptive response significantly though it showed slight anti-inflammatory effect. These experimental studies suggest that nanoemulsion and nano multiple emulsion produced a pronounced anti-inflammatory and analgesic effects in rats and may be candidates as new nanocarriers for pharmacological NSAIDs in the treatment of inflammatory disorders and alleviating pains.
- Published
- 2012
14. A novel and facile liquid whistle hydrodynamic cavitation reactor to produce submicron multiple emulsions
- Author
-
Siah Ying Tang and Manickam Sivakumar
- Subjects
Environmental Engineering ,Chromatography ,Materials science ,General Chemical Engineering ,Dispersity ,Controlled release ,Ferrous Fumarate ,Chemical engineering ,Cavitation ,Drug delivery ,Emulsion ,medicine ,Ferric ,Physical stability ,Biotechnology ,medicine.drug - Abstract
Ferrous fumarate, [C4H2FeO4] is widely utilized in the effective treatments and prevention of iron deficiency anemia. But, its administration has been oftentimes linked with quite a few side effects than ferric products. To overcome the side effects, multiple water-in-oil-in-water (W/O/W) emulsion formulations had been proposed as a new drug delivery system for the controlled release of entrapped active iron compound. In this study, high-pressure liquid whistle hydrodynamic cavitation reactor has been developed to produce highly stable W/O/W multiple emulsions containing Ferrous Fumarate in submicron scale (∼600 nm) with the droplet-size distribution polydispersity index in the narrow regime (0.35–0.40). The microscopic observations confirmed that that the physical stability of the W/O/W emulsions was increased significantly with operating pressure and number of emulsification passes. Looking at the potential for scale-up, this could be a promising technique to produce multiple emulsions incorporated with active constituents. © 2012 American Institute of Chemical Engineers AIChE J, 59: 155–167, 2013
- Published
- 2012
15. Design and evaluation of aspirin-loaded water-in-oil-in-water submicron multiple emulsions generated using two-stage ultrasonic cavitational emulsification technique
- Author
-
Siah Ying Tang and Manickam Sivakumar
- Subjects
Coalescence (physics) ,Materials science ,Aqueous solution ,Chromatography ,food.ingredient ,Renewable Energy, Sustainability and the Environment ,business.industry ,General Chemical Engineering ,Sonication ,Ultrasound ,Dispersity ,Gelatin ,food ,Chemical engineering ,Cavitation ,Ultrasonic sensor ,business ,Waste Management and Disposal - Abstract
The main goal of the present work was to develop a novel aspirin containing water-in-oil-in-water (W/O/W)-type submicron multiple emulsions via two-stage ultrasound cavitational emulsification using Span 80 and Cremophor EL as lipophilic and hydrophilic emulsifiers for the formation of primary and secondary emulsions, respectively. Effect of the following parameters, i.e. concentration of emulsifiers, ultrasonic amplitude and second sonication period on the mean droplet diameter, polydispersity index, droplet size stability and drug entrapment efficiency was studied. The osmotic behavior of the ultrasonically prepared multiple emulsions was also studied with different glucose concentrations in the inner and outer aqueous phases. The presence of gelatin played an important role in preventing interdroplet coalescence via formation of interfacial rigid film. Core shell type of multiple droplets with mean droplet diameter of around 400 nm was produced using 1.25% w/w Span 80 and 0.5% w/w Cremophor EL. The experimental results have shown that the long-term stability of the W/O/W multiple emulsions is significantly improved with the addition of both 0.5% w/w of glucose and 1% w/w of gelatin in the inner phase. This investigation has clearly proved that the use of ultrasound cavitation is an efficient yet promising approach in the generation of stable and uniform submicron multiple emulsions of aspirin. Copyright © 2012 Curtin University of Technology and John Wiley & Sons, Ltd.
- Published
- 2012
16. 2-(Trimethylsilyl)ethanol as a new alcohol equivalent for copper-catalyzed coupling of aryl iodides
- Author
-
Anjanappa Prakash, Kumaravel Selvakumar, Manickam Sivakumar, Kandasamy Ruckmani, and Mullick Dibakar
- Subjects
Ethanol ,Trimethylsilyl ,Aryl ,Organic Chemistry ,Alcohol ,Biochemistry ,Coupling (electronics) ,chemistry.chemical_compound ,chemistry ,Drug Discovery ,Copper catalyzed ,Organic chemistry ,Phenols ,2-(trimethylsilyl)ethanol - Abstract
2-(Trimethylsilyl)ethanol as a new alcohol equivalent has been employed for copper-catalyzed coupling of aryl iodides. Using mild reaction conditions, it has been observed that substituted phenols and phenols with sensitive functional groups can be readily prepared.
- Published
- 2011
17. Carbamic acid 2-trimethylsilylethyl ester as a new ammonia equivalent for palladium-catalyzed amination of aryl halides
- Author
-
Dibakar Mullick, Kandasamy Ruckmani, Manickam Sivakumar, Prakash Anjanappa, and Kumaravel Selvakumar
- Subjects
Aryl ,Organic Chemistry ,chemistry.chemical_element ,Halide ,Biochemistry ,Catalysis ,Ammonia ,chemistry.chemical_compound ,Carbamic acid ,chemistry ,Drug Discovery ,Organic chemistry ,Amination ,Palladium ,Amine derivatives - Abstract
Carbamic acid 2-trimethylsilylethyl ester (Teoc-NH 2 ) serves as an ammonia equivalent in the palladium-catalyzed amination of aryl bromides and aryl chlorides. Anilines with sensitive functional groups can be readily prepared using these amine derivatives.
- Published
- 2010
18. Synthesis of europium-doped yttrium hydroxide and yttrium oxide nanosheets
- Author
-
Yasuo Iida, Atsuya Towata, Manickam Sivakumar, Kyuichi Yasui, Teruyuki Kozuka, and Toru Tuziuti
- Subjects
Boehmite ,Materials science ,Mechanical Engineering ,Inorganic chemistry ,Oxide ,chemistry.chemical_element ,Phosphor ,Yttrium ,law.invention ,chemistry.chemical_compound ,chemistry ,Mechanics of Materials ,law ,Hydrothermal synthesis ,General Materials Science ,Calcination ,Europium ,Nanosheet - Abstract
A new approach has been developed for the preparation of Y(OH)3:Eu and Y2O3:Eu nanosheets using the sol–gel method and hydrothermal reactions. XRD patterns showed that the product was purely hexagonal-phase Y(OH)3. TEM images revealed that the nanosheets are square shaped (1 × 1 μm2) with a thickness of several tens of nanometers. In addition, it was found that cubic-phase Y2O3 nanosheets can be obtained by calcination of Y(OH)3 at 900 °C for 1 h. More importantly, the thus-prepared Y(OH)3:Eu and Y2O3:Eu nanosheet phosphors were found to exhibit a relatively high photoluminescence (PL) intensity.
- Published
- 2007
19. Ultrasound induced formation of paraffin emulsion droplets as template for the preparation of porous zirconia
- Author
-
Yasuo Iida, Teruyuki Kozuka, Atsuya Towata, Kyuichi Yasui, Manickam Sivakumar, and Toru Tuziuti
- Subjects
Zirconium ,Materials science ,Acoustics and Ultrasonics ,Organic Chemistry ,chemistry.chemical_element ,Sonochemistry ,Inorganic Chemistry ,chemistry ,Chemical engineering ,Triethanolamine ,Emulsion ,medicine ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Radiology, Nuclear Medicine and imaging ,Cubic zirconia ,Particle size ,Porous medium ,Porosity ,medicine.drug - Abstract
The paraffin particles were prepared by quenching process after sonicating the solution of paraffin and water at 80 degrees C. The resultant paraffin particles were then used as template for the preparation of macroporous zirconia materials. For this, zirconium normal butoxide (ZNB) modified with triethanolamine (TEA) was first hydrolyzed by water containing the dispersed paraffin particles with the surfactant, Sodium di(2-ethylhexyl) sulfosuccinate. This resulted in the formation of a slurry consisting of hydrolyzed sol and paraffin particles. After centrifugation, a cake packed with hydrated sol and paraffin particles were obtained which was then subjected to heat treatment. The sample obtained after heat treatment contained finely dispersed pores in the size range from 40 nm to 2 microm. Moreover, using the present approach it has also been observed that, change in pore size of zirconia wall is possible with a change in size of the paraffin particles. Thus, the present approach is a novel way of producing porous materials as the particle size of the template could be changed and templates become hard when they were molded as compared to the conventional methods in which there is no change in phase for the templates under 100 degrees C.
- Published
- 2007
20. Fabrication of Zinc Ferrite Nanocrystals by Sonochemical Emulsification and Evaporation: Observation of Magnetization and Its Relaxation at Low Temperature
- Author
-
Yasuo Iida, Tsuyoshi Takami, Manickam Sivakumar, Toru Tuziuti, Dipten Bhattacharya, Hiroshi Ikuta, Kyuichi Yasui, Teruyuki Kozuka, and Atsuya Towata
- Subjects
inorganic chemicals ,Fabrication ,Materials science ,Analytical chemistry ,Nanoparticle ,Spectroscopy, Electron Energy-Loss ,Ferric Compounds ,Sensitivity and Specificity ,Magnetics ,Magnetization ,Microscopy, Electron, Transmission ,X-Ray Diffraction ,Materials Chemistry ,Particle Size ,Physical and Theoretical Chemistry ,Aqueous solution ,Temperature ,Spectrometry, X-Ray Emission ,Evaporation (deposition) ,Surfaces, Coatings and Films ,Zinc ferrite ,Nanocrystal ,Zinc Compounds ,Emulsion ,Nanoparticles ,Emulsions ,Volatilization - Abstract
A new ultrasound assisted emulsion (consisting of rapeseed oil and aqueous solution of Zn(2+) and Fe(2+) acetates) and evaporation protocol has been developed for the synthesis of zinc ferrite (ZnFe(2)O(4)) nanoparticles with narrow size distribution. The as-synthesized sample consisted of crystalline zinc ferrite particles with an average diameter of approximately 4 nm, whereas the average size of the heat-treated ferrite particles increases to approximately 12 nm. To remove the small amount of oil present on the surface of the as-synthesized ferrite sample, heat treatment was carried out at 350 degrees C for 3 h. The as-synthesized and heat-treated ferrites were characterized by X-ray diffraction (XRD), infrared spectroscopy (IR), TGA/DTA, transmission electron microscopy (TEM), and energy dispersion X-ray spectroscopy (EDS) techniques. Magnetic measurements show that the nanocrystalline ZnFe(2)O(4), prepared through this technique, is either at par with those obtained in other cases or even more improved. Both the as-synthesized and heat-treated samples reveal relaxation of magnetization. Our study also shows that one can tailor the magnetization and relaxation pattern by suitably controlling the particle size of the nanocrystalline ZnFe(2)O(4). The key features of this method are avoiding (a) the cumbersome conditions that exist in the conventional methods, (b) the usage of necessary additive components (stabilizers or surfactants, precipitants), and (c) calcination requirements. In addition, rapeseed oil has replaced organic nonpolar solvents used in earlier studies. As a whole, this simple straightforward sonochemical approach results in a better pure phase system of nanoferrite with improved magnetic properties.
- Published
- 2006
21. Acoustic cavitation—an efficient energetic tool to synthesize nanosized CuO–ZrO2catalysts with a mesoporous distribution
- Author
-
Aharon Gedanken, Manickam Sivakumar, Luwei Chen, and Ziyi Zhong
- Subjects
Chemistry ,Precipitation (chemistry) ,Mineralogy ,General Chemistry ,Catalysis ,law.invention ,X-ray photoelectron spectroscopy ,Chemical engineering ,law ,Cavitation ,Materials Chemistry ,Calcination ,Ultrasonic sensor ,Mesoporous material ,Intensity (heat transfer) - Abstract
A CuO–ZrO2 catalyst of nanometer size was prepared using a simple precipitation technique, assisted by cavitation, and induced by an environmentally friendly ultrasonic technique. BET surface areas of 349.2 m2 g−1 for the as-prepared catalyst and 72.4 m2 g−1 for the catalyst calcined in air at 500 °C were obtained when the precursors were subjected to 70% ultrasonic intensity for 4 h. On the other hand, by following a conventional precipitation method using similar precursors, a surface area of 72 m2 g−1 was obtained when the precursors were heated to only 80 °C for 20 h. More importantly, only the application of ultrasound lead to the formation of a mesoporous structure. To confirm the ultrasonic cavitational effect in this process, the affect of the ultrasonic intensity in increasing the surface area, as well as in generating the mesopores, was also investigated. Furthermore, from studies of the catalytic activity for decomposing N2O, it has been observed that the catalyst obtained with 70% ultrasonic intensity clearly exhibits an increased activity compared to the catalyst prepared using 20% ultrasonic intensity. These results clearly indicate that ultrasound-induced cavitation is a new and rapid method for the preparation of supported catalysts. The products were characterized by nitrogen adsorption–desorption isotherms, TGA, XRD, TEM, EDAX, XPS and XRF measurements.
- Published
- 2006
22. A Combined Ink Jet Printing/Photo-reduction Process for the Fabrication of μm-size Conductive Tracks
- Author
-
Jonathan Stringer, Brian Derby, Nuno Reis, Victor Oliveira, Manickam Sivakumar, and Rui Vilar
- Published
- 2006
23. Ultrasound as a Green Processing Technology for Pretreatment and Conversion of Biomass into Biofuels
- Author
-
Siah Ying Tang and Manickam Sivakumar
- Subjects
Biodiesel ,food and beverages ,Biomass ,Pulp and paper industry ,Sustainable biofuel ,complex mixtures ,chemistry.chemical_compound ,chemistry ,Biogas ,Biofuel ,Enzymatic hydrolysis ,Environmental science ,Cellulose ,High frequency ultrasound - Abstract
In the past decades, a great deal of attention has been focused on mechanical, thermal or chemical pretreatments of lignocellulosic and algal biomass for the production of biofuel. This chapter is focused on the potential of ultrasound (US) technology in pretreating the biomass to enhance the conversion of cellulose to fermentable sugars and also the disintegration and component extraction of microalgae for the generation of bioethanol or biogas. In addition, US can supplement existing biomass pretreatment methods to greatly enhance their performance and their efficacy. Low frequency ultrasound (LFU, 20–100 kHz) is commonly used in biomass processing, particularly in processes that require intense physical effects such as cell disruption and polymer degradation. High frequency ultrasound (HFU, 400 kHz–2 MHz) recently attracted considerable interest as potential alternative technique for pretreating both the lignocellulosic and algal biomass for sustainable biofuel production. HFU is gaining increasing importance because of its environmentally sound and energy-saving production method since it demands lower energy input for the conversion of biomass. It not only saves time and energy but also lowers the chemical/enzyme dosage and hence novel and considered to be a new sustainable and environmentally-friendly green technique. Although many studies have shown the promise of ultrasound in the cell breakdown for enhanced enzymatic hydrolysis, there is limited information in the application of HFU on biomass pretreatment processes. This chapter provides an overview on the fundamentals of US, the critical parameters that control the conversion of biomass, challenges involved with the application of US in the biomass conversion and its future perspectives.
- Published
- 2014
24. Sonochemistry and its dosimetry
- Author
-
Manickam Sivakumar, Kyuichi Yasui, Yasuo Iida, and Toru Tuziuti
- Subjects
chemistry.chemical_classification ,Dosimeter ,business.industry ,Chemistry ,Ultrasound ,Iodide ,Analytical chemistry ,Analytical Chemistry ,Sonochemistry ,Ultrasonic irradiation ,Bubble cavitation ,Cavitation ,Dosimetry ,business ,Spectroscopy ,Nuclear chemistry - Abstract
The effects of ultrasound originate primarily in acoustic cavitation. The cavitation bubbles collapse violently enough to lead to interesting chemical effects, known as sonochemistry. There is a great need to relate the efficiency of sonochemical reaction to the energy of ultrasonic irradiation used to produce them. In this paper, three OH radical dosimeters, Fricke dosimeter, terephthalate dosimeter, and iodide dosimeter, are compared from the analytical point of view. The dosimeters based on photometry, i.e., Fricke and iodide, produced reliable and reproducible results, but the sensitivity is not enough for special applications, such as chemical monitoring of single bubble cavitation. The dosimeter based on fluorometry, terephthalate dosimeter, offered high sensitivity, 1.2×10 11 molecules ml −1 . The effects of some experimental parameters in sonochemistry, i.e., solution temperature and the dissolved gas species, were evaluated with the dosimeters.
- Published
- 2005
25. A sonochemical method for the synthesis of polyaniline and Au–polyaniline composites using H2O2 for enhancing rate and yield
- Author
-
Manickam Sivakumar and Aharon Gedanken
- Subjects
Conductive polymer ,Materials science ,Polyaniline nanofibers ,Mechanical Engineering ,Metals and Alloys ,Nanotechnology ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,Sonochemistry ,Reaction rate ,chemistry.chemical_compound ,Chemical engineering ,Polymerization ,chemistry ,Mechanics of Materials ,Yield (chemistry) ,Polyaniline ,Materials Chemistry ,Energy source - Abstract
We report on a simple and novel sonochemical method for the preparation of polyaniline (PANI), as well as its composite, with Au nanoparticles. This technique utilizes ultrasound radiation as an energy source to facilitate the reaction by reducing the reaction time, as well as significantly increasing the yield. The tremendous increase in the reaction rates is explained on the basis of the intensive bubble collapse conditions, which rapidly generate the oxidative radicals necessary for polymerization.
- Published
- 2005
26. Synthesis of Alumina Macroporous Materials Using Yeast Cells as Bio-Templates
- Author
-
Toru Tuziuti, Manickam Sivakumar, Teruyuki Kozuka, Atsuya Towata, Yasuo Iida, and Kyuichi Yasui
- Subjects
Chromatography ,Materials science ,General Chemistry ,Aluminium isopropoxide ,Condensed Matter Physics ,Yeast ,chemistry.chemical_compound ,Hydrolysis ,Template ,Chemical engineering ,chemistry ,Triethanolamine ,Materials Chemistry ,Ceramics and Composites ,Slurry ,medicine ,medicine.drug - Abstract
Macroporous alumina materials were synthesized by using yeast cells as bio-templates. Aluminium isopropoxide (AIP) modified with triethanolamine (TEA) was first hydrolyzed by water containing the dispersed yeast cells. This resulted in the formation of slurry consisting of hydrolyzed sol and yeast cells. After centrifuging, the cake which is packed with hydrated sol and yeast cells was subjected to heat treatment. The obtained sample after heat treatment contained finely dispersed pores ranging in size from 1.5 to 2.0 μm. Under the present experimental conditions, the thickness of alumina wall was also controlled by changing the ratio of yeast cells to AIP.
- Published
- 2005
27. Fabrication of Zirconia Hollow Spheres on Yeast Cell Templates
- Author
-
Yasuo Iida, Kyuichi Yasui, Toru Tuziuti, Manickam Sivakumar, and Atsuya Towata
- Subjects
Fluid Flow and Transfer Processes ,Zirconium ,Aqueous solution ,Fabrication ,Materials science ,Process Chemistry and Technology ,Shell (structure) ,chemistry.chemical_element ,Filtration and Separation ,Nanotechnology ,engineering.material ,Catalysis ,Yeast ,chemistry ,Chemical engineering ,Coating ,Triethanolamine ,engineering ,medicine ,Cubic zirconia ,medicine.drug - Abstract
Zirconia hollow spheres were prepared using yeast cells as templates. Zirconium butoxide (ZNB) was used as a precursor and treated with triethanolamine (TEA) in order to obtain a basic aqueous zirconium hydroxide solution. Thus obtained basic zirconium hydroxide solution was then nucleated heterogeneously using yeast cells as templates. The results of this investigation show that the formed zirconia hollow spheres either keep the shape of the yeast cells or otherwise have a wrinkled shell. The shell of hollow spheres heated at 973K for 3 hours was from 0.1 to 0.25μm in thickness and consisted of the nano crystals.
- Published
- 2005
28. Fabrication of bimodal (meso/macro) porous alumina materials using yeast cells as templates
- Author
-
Toru Tuziuti, Kazutoku Ohta, Teruyuki Kozuka, Manickam Sivakumar, Kyuichi Yasui, Yasuo Iida, and Atsuya Towata
- Subjects
Fabrication ,Materials science ,Sintering ,Bioengineering ,Surfaces and Interfaces ,Aluminium isopropoxide ,Condensed Matter Physics ,Yeast ,Surfaces, Coatings and Films ,chemistry.chemical_compound ,Hydrolysis ,chemistry ,Chemical engineering ,Mechanics of Materials ,Triethanolamine ,Slurry ,medicine ,Composite material ,Porosity ,Biotechnology ,medicine.drug - Abstract
Bimodal (meso/macro) porous alumina materials were synthesized using yeast cells as bio-templates. Aluminium isopropoxide (AIP) modified with triethanolamine (TEA) was first hydrolyzed by water containing the dispersed yeast cells. This resulted in the formation of slurry consisting of hydrolyzed sol and yeast cells. After centrifuging the solution, the obtained cake which is packed with hydrated sol and yeast cells was subjected to heat treatment. The sample after heat treatment contained finely dispersed bimodal (meso/ macro) pores ranging in size from 1.5 to 2.0 μm and several nm. Under the present experimental conditions, the thickness of alumina wall was also controlled by changing the ratio of yeast cells to AIP. It was also observed that with an increase in the thickness of the wall, the size of the pores decreased. [DOI: 10.1380/ejssnt.2005.405]
- Published
- 2005
29. Sonoluminescence
- Author
-
Kyuichi Yasui, Toru Tuziuti, Manickam Sivakumar, and Yasuo Iida
- Subjects
Instrumentation ,Spectroscopy - Published
- 2004
30. Insights into the sonochemical decomposition of Fe(CO)5: theoretical and experimental understanding of the role of molar concentration and power density on the reaction yield
- Author
-
Aharon Gedanken and Manickam Sivakumar
- Subjects
Materials science ,Molar concentration ,Acoustics and Ultrasonics ,Organic Chemistry ,Metallurgy ,Decomposition ,Nanocrystalline material ,Amorphous solid ,Sonochemistry ,Inorganic Chemistry ,chemistry.chemical_compound ,Decalin ,chemistry ,Chemical engineering ,Yield (chemistry) ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Radiology, Nuclear Medicine and imaging ,Power density - Abstract
The present work analyses, in detail, the optimization of a sonochemical process with respect to concentration of precursor and power supplied in a system. This is due to that even a small change in power dramatically changes the high-energy conditions created with the bubble collapse. A model reaction that has been considered for this purpose involves the decomposition of Fe(CO)5 in decalin solvent as this reaction is strongly influenced by the cavitation conditions. Sonochemical treatment of this carbonyl results in the formation of amorphous Fe2O3, which on heat treatment gives nanocrystalline Fe2O3. It has been observed that concentration and power density parameters play an important role to obtain higher decomposition of Fe(CO)5 and hence higher yield of the amorphous Fe2O3 product. Also, using the experimentally observed results, a correlation (polynomial) has been developed.
- Published
- 2004
31. Correlation in spatial intensity distribution between volumetric bubble oscillations and sonochemiluminescence in a multibubble system
- Author
-
Manickam Sivakumar, Kyuichi Yasui, Yasuo Iida, and Toru Tuziuti
- Subjects
business.industry ,Chemistry ,Bubble ,General Chemistry ,Light scattering ,Physics::Fluid Dynamics ,Standing wave ,Wavelength ,Light intensity ,Optics ,Cavitation ,business ,Sound pressure ,Intensity (heat transfer) - Abstract
The correlation in spatial intensity distribution between volumetric oscillation of multibubble and sonochemiluminescence in an ultrasonic standing-wave field is investigated through the measurements of scattered light from bubbles by changing the measuring position in the direction of sound propagation and sonochemiluminescence with luminol. When a thin light sheet, finer than half the wavelength of sound, is introduced into the cavitation bubbles at the anti-node of the sound pressure, the scattered light intensity oscillates temporally. The peak-to-peak light intensity corresponds to the number of the bubbles which contribute to the sonochemical reaction because the radius for oscillating bubbles at pressure antinode is restrictive in a certain range due to the shape instability and the action of Bjerknes force that expels from anti-node bubbles larger than the resonant size. The experimental results show that at the side near the water surface, the peak-to-peak light intensity is larger in comparison with the intensity near the sound source, and this tendency becomes apparent at higher input power. These light scattering results correspond with the spatial intensity distribution of the sonochemiluminescence with luminol. Therefore, it is interpreted that most of the cavitation bubbles contributing to the sonochemical reactions in the standing wave field exist near liquid surface. Present method of light scattering in reference with the image of the sonochemiluminescence is promising for evaluating spatial distribution of violently oscillating cavitation bubbles effective for sonochemical reactions.
- Published
- 2004
32. Preparation of nanosized TiO2 supported on activated alumina by a sonochemical method: observation of an increased photocatalytic decolourisation efficiency
- Author
-
Kyuichi Yasui, Yasuo Iida, Toru Tuziuti, and Manickam Sivakumar
- Subjects
Aqueous solution ,Materials science ,Activated alumina ,General Chemistry ,engineering.material ,Sonochemistry ,Catalysis ,chemistry.chemical_compound ,Adsorption ,Coating ,Chemical engineering ,chemistry ,engineering ,Photocatalysis ,Methyl orange - Abstract
Nanosized TiO2 supported on activated alumina was prepared using a sonochemical method. To prepare this supported material, direct immersion horn and cup horn ultrasonic systems were used. The efficiency of the sonochemical coating process was determined by UV photodecolourisation of the aqueous methyl orange solution. It was found that TiO2 supported on activated alumina prepared by the sonochemical method gave the maximum decolourisation efficiency. In that method itself, direct immersion horn gave a higher photodecolourisation activity as compared to the cup horn. The obtained results suggest that the direct immersion horn results in uniform, as well as a maximum number of TiO2 particles to be adsorbed on an activated alumina surface.
- Published
- 2004
33. Destruction of Rhodamine B using novel sonochemical reactor with capacity of 7.5 l
- Author
-
Aniruddha B. Pandit, Manickam Sivakumar, and Parag R. Gogate
- Subjects
Pollutant ,Engineering ,business.industry ,Scale (chemistry) ,Environmental engineering ,Filtration and Separation ,Dissipation ,Decomposition ,Analytical Chemistry ,chemistry.chemical_compound ,chemistry ,Rhodamine B ,Degradation (geology) ,Engineering design process ,Process engineering ,business ,Intensity (heat transfer) - Abstract
Sonochemical reactors offer excellent promise in the wastewater treatment applications due to the creation of local hotspots with overall ambient operating conditions and release of highly reactive free radicals. However, its application in the actual industrial practice is hampered by the fact that the existing available information related to the optimization of operating parameters is restricted mainly to small scale operations with reported experiments with capacity in the range of few milliliters to 1 l. With this information, efficient scale up and successful operation of industrial scale reactors is almost impossible. Thus, design of novel large-scale sonochemical reactors and subsequent testing of the same for destruction of different pollutants is the need of the present hour. In an attempt to move one step ahead in the design process, a novel sonochemical reactor with a capacity of 7.5 l has been developed and tested using destruction of Rhodamine B as a model reaction. Effect of various operating parameters such as frequency of irradiation, use of multiple frequencies and power dissipation into the system on the extent of degradation has been studied. Experiments have also been performed with the KI decomposition (model reaction typically used in investigating cavitational effects) so as to establish the dependency of the trends in the variation of the extent of degradation with the operating parameters on the cavitational intensity requirements for a specific application. For the degradation of Rhodamine B, power dissipation into the system was found to be the controlling parameter and the extent of degradation is directly proportional to the power dissipation with a coefficient of 74.1.
- Published
- 2004
34. Wastewater treatment: a novel energy efficient hydrodynamic cavitational technique
- Author
-
Manickam Sivakumar and Aniruddha B. Pandit
- Subjects
Work (thermodynamics) ,Materials science ,Acoustics and Ultrasonics ,business.industry ,Organic Chemistry ,Orifice plate ,Inorganic Chemistry ,chemistry.chemical_compound ,Optics ,Chemical engineering ,chemistry ,Cavitation ,Rhodamine B ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Degradation (geology) ,Radiology, Nuclear Medicine and imaging ,Sewage treatment ,business ,Efficient energy use - Abstract
A novel method of treating a dye solution has been studied by hydrodynamic cavitation using multiple hole orifice plates. The present work deals with the effect of geometry of the multiple hole orifice plates on the degradation of a cationic dye rhodamine B (rhB) solution. The efficiency of this technique has been compared with the cavitation generated by ultrasound and it has been found that there is substantial enhancement in the extent of degradation of this dye solution using hydrodynamic cavitation. Large-scale operation coupled with better energy efficiency makes this technique a viable alternative for conventional cavitational reactors.
- Published
- 2002
35. Kinetics of p-nitrophenol degradation: effect of reaction conditions and cavitational parameters for a multiple frequency system
- Author
-
Prashant A. Tatake, Aniruddha B. Pandit, and Manickam Sivakumar
- Subjects
Aqueous solution ,Chemistry ,General Chemical Engineering ,Kinetics ,Analytical chemistry ,Mineralogy ,General Chemistry ,Kinetic energy ,Industrial and Manufacturing Engineering ,Sonochemistry ,Nitrophenol ,chemistry.chemical_compound ,Reaction rate constant ,Environmental Chemistry ,Degradation (geology) ,Ultrasonic sensor - Abstract
In order to assess the ultrasound dual frequency effects, sonochemical degradation of p-nitrophenol (p-NP) in an aqueous solution has been carried out with ultrasound at three operating frequencies, i.e., at 25, 40 kHz each independently, and the combination of two frequencies (25+40 kHz) simultaneously. Based on the rates of degradation, a kinetic study has been performed which leads to the evaluation of apparent kinetic rate constants for the degradation of p-NP. The influence of various parameters including initial solution pH, bulk solution temperature, on the degradation of p-NP was studied for these three frequency modes (25, 40 and 25+40 kHz) in order to investigate the temporal behaviour of this reaction, especially when it was operated in combined mode (25+40 kHz). The energy efficiency in the case of dual frequency mode is much better than single frequency modes. Modelling and cavity dynamics simulations have also been carried out to explain the observed effects. During combined mode operation, an improvement in the rate of degradation has been observed. The variation in the rate constants has been explained based on the difference in the acoustic pressure field in different systems including ultrasonic bath and dual frequency processor.
- Published
- 2002
36. Cavitation reactors: Efficiency assessment using a model reaction
- Author
-
Nilesh P. Vichare, Aniruddha B. Pandit, P. Senthilkumar, Irfan Z. Shirgaonkar, Manickam Sivakumar, and Parag R. Gogate
- Subjects
Environmental Engineering ,Aqueous solution ,Chemistry ,General Chemical Engineering ,Orifice plate ,Mineralogy ,Mechanics ,Decomposition ,Chemical reaction ,Reaction rate ,Yield (chemistry) ,Cavitation ,Chemical change ,Biotechnology - Abstract
Acoustic and hydrodynamic cavitation can be used for a variety of applications ranging from biological applications such as cell disruption to chemical reactions such as oxidation of organic pollutants in aqueous effluents, including biorefractory toxic chemicals. Different equipment used for cavitational effects was compared based on a model reaction (decomposition of potassium iodide resulting into iodine liberation). A correlation was developed for the prediction of the cavitational yield in terms of the cavity collapse pressure. This correlation, when used with earlier correlations for the pressure amplitude generated during the violent collapse of cavities, will help design engineers to choose particular equipment, operating conditions, and geometric parameters to achieve a desired chemical change. The developed equation relating the macroscopic reaction rates with the collapse pressure is the first of its kind reported in the literature. Pilot-plant-scale hydrodynamic cavitation orifice plate setup is most energy-efficient, with significantly higher cavitational yields for the model reaction.
- Published
- 2001
37. ULTRASOUND ENHANCED PTC CONVERSION OF BENZAMIDE TO BENZONITRILE
- Author
-
Paramasivam Senthilkumar, Manickam Sivakumar, and Aniruddha B. Pandit
- Subjects
Reaction rate ,Benzonitrile ,chemistry.chemical_compound ,endocrine system diseases ,chemistry ,business.industry ,Organic Chemistry ,Ultrasound ,Model system ,Benzamide ,Photochemistry ,business ,Beneficial effects - Abstract
Enhancement of the reaction rate by combining the beneficial effects of PTC and ultrasound has been explored in the present study by taking the transformation of benzamide by dehydration to give benzonitrile as a model system. It was found that there is a substantial reduction in the reaction time when ultrasound was coupled with PTC.
- Published
- 2001
38. A new ultrasonic cavitation approach for the synthesis of zinc ferrite nanocrystals
- Author
-
Toru Tuziuti, Manickam Sivakumar, Atsuya Towata, Yasuo Iida, and Kyuichi Yasui
- Subjects
Materials science ,Metallurgy ,General Physics and Astronomy ,chemistry.chemical_element ,Zinc ,Sonochemistry ,Zinc ferrite ,chemistry ,Chemical engineering ,Nanocrystal ,Ultrasonic cavitation ,Nano ,Emulsion ,Ferrite (magnet) ,General Materials Science - Abstract
An ultrasound mediated simple emulsion process has been demonstrated for the synthesis of zinc ferrite nanocrystals using the precursors of zinc and iron acetates and rapeseed oil. Following this technique avoids many of the outstanding problems that normally exist in conventional emulsion synthesis. Due to the simplicity of this process, it could also become a valuable starting point for the generation of other mixed and complex ferrites.
- Published
- 2006
39. Mechanistic investigation of the sonochemical synthesis of zinc ferrite
- Author
-
Amit Choudhary, Vijayanand S. Moholkar, Manickam Sivakumar, and Hanif A. Choudhury
- Subjects
Shock wave ,Materials science ,Acoustics and Ultrasonics ,Bubble ,Organic Chemistry ,Metallurgy ,Oxide ,law.invention ,Sonochemistry ,Inorganic Chemistry ,chemistry.chemical_compound ,Zinc ferrite ,Chemical engineering ,chemistry ,law ,Cavitation ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Ferrite (magnet) ,Radiology, Nuclear Medicine and imaging ,Calcination - Abstract
In this investigation, an attempt has been made to establish the physical mechanism of sonochemical synthesis of zinc ferrite with concurrent analysis of experimental results and simulations of cavitation bubble dynamics. Experiments have been conducted with mechanical stirring as well as under ultrasound irradiation with variation of pH and the static pressure of the reaction medium. Results of this study reveal that physical effects produced by transient cavitation bubbles play a crucial role in the chemical synthesis. Generation of high amplitude shock waves by transient cavitation bubbles manifest their effect through in situ micro-calcination of metal oxide particles (which are generated through thermal hydrolysis of metal acetates) due to energetic collisions between them. Micro-calcination of oxide particles can also occur in the thin liquid shell surrounding bubble interface, which gets heated up during transient collapse of bubbles. The sonochemical effect of production of OH radicals and H(2)O(2), in itself, is not able to yield ferrite. Moreover, as the in situ micro-calcination involves very small number of particles or even individual particles (as in intra-particle collisions), the agglomeration between resulting ferrite particles is negligible (as compared to external calcination in convention route), leading to ferrite particles of smaller size (6 nm).
- Published
- 2012
40. ChemInform Abstract: Efficient Indoles and Anilines Synthesis Employing tert-Butyl Sulfinamide as Ammonia Surrogate
- Author
-
Mullick Dibakar, Manickam Sivakumar, Kumaravel Selvakumar, Kandasamy Ruckmani, and Anjanappa Prakash
- Subjects
Coupling (electronics) ,Tert butyl ,chemistry.chemical_compound ,Ammonia ,chemistry ,Sulfinamide ,Aryl ,Polymer chemistry ,Halide ,chemistry.chemical_element ,General Medicine ,Catalysis ,Palladium - Abstract
Palladium catalyzed coupling of sulfinamide (II) with aryl halides gives sulfinated anilines which can be deprotected with HCl.
- Published
- 2012
41. ChemInform Abstract: 2-(Trimethylsilyl)ethanol as a New Alcohol Equivalent for Copper-Catalyzed Coupling of Aryl Iodides
- Author
-
Manickam Sivakumar, Anjanappa Prakash, Kandasamy Ruckmani, Kumaravel Selvakumar, and Mullick Dibakar
- Subjects
Coupling (electronics) ,chemistry.chemical_compound ,chemistry ,Aryl ,Copper catalyzed ,Alcohol ,General Medicine ,2-(trimethylsilyl)ethanol ,Phenols ,Cleavage (embryo) ,Silane ,Medicinal chemistry - Abstract
Coupling of aryl iodides bearing various functionalities including sensitive ones with alcohol (II) and subsequent silane cleavage allows the synthesis of substituted phenols under mild conditions.
- Published
- 2011
42. Ultrasonic cavitation induced water in vegetable oil emulsion droplets--a simple and easy technique to synthesize manganese zinc ferrite nanocrystals with improved magnetization
- Author
-
M Maiorov, Teruyuki Kozuka, Mahalingam Ashok, Atsuya Towata, Manickam Sivakumar, Yasuo Iida, Neelagesi Sivakumar, Kyuichi Yasui, Dipten Bhattacharya, Toru Tuziuti, and Elmars Blums
- Subjects
Materials science ,Acoustics and Ultrasonics ,Analytical chemistry ,chemistry.chemical_element ,Zinc ,Radiation Dosage ,Ferric Compounds ,law.invention ,Sonochemistry ,High-Energy Shock Waves ,Inorganic Chemistry ,Magnetization ,Magnetics ,Sonication ,law ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Plant Oils ,Radiology, Nuclear Medicine and imaging ,Crystallization ,Aqueous solution ,Organic Chemistry ,Metallurgy ,Water ,Nanocrystalline material ,Nanostructures ,chemistry ,Manganese Compounds ,Emulsion ,Ferrite (magnet) ,Emulsions - Abstract
In the present investigation, synthesis of manganese zinc ferrite (Mn(0.5)Zn(0.5)Fe(2)O(4)) nanoparticles with narrow size distribution have been prepared using ultrasound assisted emulsion (consisting of rapeseed oil as an oil phase and aqueous solution of Mn(2+), Zn(2+) and Fe(2+) acetates) and evaporation processes. The as-prepared ferrite was nanocrystalline. In order to remove the small amount of oil present on the surface of the ferrite, it was subjected to heat treatment at 300 °C for 3h. Both the as-prepared and heat treated ferrites have been characterized by X-ray diffraction (XRD), infrared spectroscopy (IR), TGA/DTA, transmission electron microscopy (TEM) and energy dispersion X-ray spectroscopy (EDS) techniques. As-prepared ferrite is of 20 nm, whereas the heat treated ferrite shows the size of 33 nm. In addition, magnetic properties of the as-prepared as well as the heat treated ferrites have also been carried out and the results of which show that the spontaneous magnetization (σ(s)) of the heat treated sample (24.1 emu/g) is significantly higher than that of the as-synthesized sample (1.81 emu/g). The key features of this method are avoiding (a) the cumbersome conditions that exist in the conventional methods; (b) usage of necessary additive components (stabilizers or surfactants, precipitants) and (c) calcination requirements. In addition, rapeseed oil as an oil phase has been used for the first time, replacing the toxic and troublesome organic nonpolar solvents. As a whole, this simple straightforward sonochemical approach results in more phase pure system with improved magnetization.
- Published
- 2011
43. ChemInform Abstract: Carbamic Acid 2-Trimethylsilylethyl Ester as a New Ammonia Equivalent for Palladium-Catalyzed Amination of Aryl Halides
- Author
-
Dibakar Mullick, Kandasamy Ruckmani, Manickam Sivakumar, Kumaravel Selvakumar, and Prakash Anjanappa
- Subjects
Ammonia ,chemistry.chemical_compound ,Carbamic acid ,chemistry ,Aryl ,chemistry.chemical_element ,Organic chemistry ,Halide ,General Medicine ,Amination ,Catalysis ,Amine derivatives ,Palladium - Abstract
Carbamic acid 2-trimethylsilylethyl ester (Teoc-NH 2 ) serves as an ammonia equivalent in the palladium-catalyzed amination of aryl bromides and aryl chlorides. Anilines with sensitive functional groups can be readily prepared using these amine derivatives.
- Published
- 2011
44. ChemInform Abstract: Ultrasound Enhanced PTC Conversion of Benzamide to Benzonitrile
- Author
-
Aniruddha B. Pandit, Paramasivam Senthilkumar, and Manickam Sivakumar
- Subjects
endocrine system diseases ,business.industry ,Ultrasound ,Model system ,General Medicine ,Photochemistry ,medicine.disease ,Reaction rate ,chemistry.chemical_compound ,Benzonitrile ,chemistry ,medicine ,Dehydration ,Benzamide ,business ,Beneficial effects - Abstract
Enhancement of the reaction rate by combining the beneficial effects of PTC and ultrasound has been explored in the present study by taking the transformation of benzamide by dehydration to give benzonitrile as a model system. It was found that there is a substantial reduction in the reaction time when ultrasound was coupled with PTC.
- Published
- 2010
45. Dependence of sonochemical parameters on the platinization of rutile titania - an observation of a pronounced increase in photocatalytic efficiencies
- Author
-
Teruyuki Kozuka, Toru Tuziuti, Atsuya Towata, Manickam Sivakumar, Kyuichi Yasui, and Yasuo Iida
- Subjects
Materials science ,Acoustics and Ultrasonics ,Sonication ,Organic Chemistry ,Inorganic chemistry ,Catalysis ,Sonochemistry ,Inorganic Chemistry ,Propanol ,chemistry.chemical_compound ,chemistry ,Rutile ,Photocatalysis ,Methyl orange ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Radiology, Nuclear Medicine and imaging ,Photodegradation - Abstract
Using a standing wave sonochemical reactor (SWSR), the influences of parameters of ultrasonic power input, sonication time, sonication temperature and the amount of propanol (which generates the reducing radicals) were systemically investigated to ascertain and optimize the best conditions for the sonochemical reduction of Pt from its precursor hexachloroplatinic acid and then its deposition on rutile TiO(2) (platinization of rutile titania) catalysts. Catalytic activity of the prepared platinized catalysts was tested in the reaction of methyl orange degradation. The results of photocatalytic activity study in the degradation of methyl orange further demonstrate that sonochemically as-prepared Pt/TiO(2) catalysts show a pronounced increase ( approximately 2 times) in photodegradation, even with a deposition of small amounts of platinum (1.4wt.%), as compared to the unsupported or naked rutile titania. Although there are various parameters that influence the sonochemical platinization of rutile titania, the present optimization results clearly indicate that the best photocatalytic degradation of methyl orange can be obtained when the experimental conditions of the preparation were with an input power of 50W, an initial hexachloroplatinic acid volume of 70ml (which results into 1.4wt.% Pt on TiO(2)), sonication time of 90min, 0.18g of propanol and a temperature of 10 degrees C were adopted. The method of ultrasound application to prepare metal supported semiconductors has many advantages such as convenience, safety and high efficiency. Furthermore, it is hopeful that this optimization study can also be extended to the generation of similar metal supported semiconductors.
- Published
- 2009
46. Physical facets of ultrasonic cavitational synthesis of zinc ferrite particles
- Author
-
Thirugnanasambandam Sivasankar, Bhaskar Rao Reddy, Vijayanand S. Moholkar, and Manickam Sivakumar
- Subjects
Nanostructure ,Acoustics and Ultrasonics ,Radical ,Acetates ,Ferric Compounds ,Sonochemistry ,Inorganic Chemistry ,Hydrolysis ,Materials Testing ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Radiology, Nuclear Medicine and imaging ,Ultrasonics ,Particle Size ,Ions ,Hydroxyl Radical ,Organic Chemistry ,Metallurgy ,Acoustics ,Equipment Design ,Models, Theoretical ,Peroxides ,Zinc ferrite ,Chemistry ,Zinc ,Chemical engineering ,Cavitation ,Thermodynamics ,Ultrasonic sensor ,Particle size - Abstract
This paper addresses the physical features of the ultrasonic cavitational synthesis of zinc ferrite particles and tries to establish the relationship between cavitation physics and sonochemistry of the zinc ferrite synthesis. A dual approach of coupling experimental results with simulations of radial motion of cavitation bubbles has been adopted. The precursors for the zinc ferrite, viz. ZnO and Fe(3)O(4) are produced in situ by the hydrolysis of Zn and Fe(II) acetates stimulated by (*)OH radicals produced from the transient collapse of the cavitation bubbles. Experiments performed under different conditions create significant variation in the production of (*)OH radicals, and hence, the rate of acetate hydrolysis. Correlation of the results of experiments and simulations sheds light on the important facets of the physical mechanism of ultrasonic cavitational zinc ferrite synthesis. It is revealed that too much or too little rate of acetate hydrolysis results in smaller particle size of zinc ferrite. The first effect of a higher rate of hydrolysis leads to excessively large growth of particles, due to which they become susceptible to the disruptive action of cavitation bubbles. Whereas, the second effect of too small rate of hydrolysis of Zn and Fe(II) acetates restricts the growth of particles. It has been observed that the initial reactant concentration does not influence the mean particle size or the size distribution of zinc ferrite particles. The present investigation clearly confirms that the rate-controlling step of zinc ferrite synthesis through ultrasonic cavitational route is the rate of formation of (*)OH radicals from cavitation bubbles.
- Published
- 2009
47. Fabrication of nanosized Pt on rutile TiO2 using a standing wave sonochemical reactor (SWSR)--observation of an enhanced catalytic oxidation of CO
- Author
-
Manickam Sivakumar, Atsuya Towata, Toru Tuziuti, Masahiko Tsujimoto, Ziyi Zhong, Teruyuki Kozuka, Yasuo Iida, and Kyuichi Yasui
- Subjects
Materials science ,Acoustics and Ultrasonics ,Diffuse reflectance infrared fourier transform ,Analytical chemistry ,Radiation Dosage ,Catalysis ,Sonochemistry ,Inorganic Chemistry ,Sonication ,Transition metal ,X-ray photoelectron spectroscopy ,Chemical Engineering (miscellaneous) ,Environmental Chemistry ,Nanotechnology ,Radiology, Nuclear Medicine and imaging ,Platinum ,Titanium ,Organic Chemistry ,Equipment Design ,Carbon Dioxide ,Nanostructures ,Equipment Failure Analysis ,Catalytic oxidation ,Chemical engineering ,Rutile ,Particle ,Adsorption ,Oxidation-Reduction - Abstract
Fine particles of rutile TiO2 supporting nanosized particles of Pt were prepared by a simultaneous in situ sonochemical reduction and deposition method using a standing wave sonochemical reactor (SWSR). The mean diameter of sonochemically obtained Pt particles are of 2 nm. Following this sonochemical technique, rutile TiO2 was also deposited with different weight percentages of Pt. Catalytic function of the prepared composite catalysts were tested by the oxidation of CO to CO(2). From the catalytic activity results, it has been found out that the catalysts prepared by the sonochemical method exhibited higher catalytic activity for CO oxidation, probably attributed to the higher Pt particle distribution achieved under sonication. Transmission electron microscopy (TEM), X-ray photoelectron spectra (XPS), and diffuse reflectance spectroscopy (DRS) were employed to characterize the resulting material.
- Published
- 2009
48. ChemInform Abstract: 2-(Trimethylsilyl)ethanesulfonyl Amide as a New Ammonia Equivalent for Palladium-Catalyzed Amination of Aryl Halides
- Author
-
Manickam Sivakumar, Kumaravel Selvakumar, Prakash Anjanappa, and Dibakar Mullick
- Subjects
chemistry.chemical_compound ,Ammonia ,Trimethylsilyl ,chemistry ,Amide ,Aryl ,chemistry.chemical_element ,Halide ,General Medicine ,Medicinal chemistry ,Amination ,Palladium ,Catalysis - Abstract
2-(Trimethylsilyl)ethanesulfonyl amide (SES-NH2) is an ammonia equivalent for the palladium-catalyzed amination of aryl bromides and aryl chlorides. Using these amine derivatives, it has been observed that anilines and anilines with sensitive functional groups can be readily prepared.
- Published
- 2008
49. Methotrexate loaded solid lipid nanoparticles (SLN) for effective treatment of carcinoma
- Author
-
Ganeshkumar Pa, Kandasamy Ruckmani, and Manickam Sivakumar
- Subjects
Drug ,Male ,Antimetabolites, Antineoplastic ,Materials science ,Metabolic Clearance Rate ,media_common.quotation_subject ,Biomedical Engineering ,Nanoparticle ,Bioengineering ,Pharmacology ,chemistry.chemical_compound ,Mice ,Pharmacokinetics ,Solid lipid nanoparticle ,medicine ,Carcinoma ,Animals ,General Materials Science ,Particle Size ,media_common ,Drug Carriers ,Chromatography ,General Chemistry ,Neoplasms, Experimental ,Condensed Matter Physics ,medicine.disease ,Lipids ,Nanostructures ,Survival Rate ,Methotrexate ,Treatment Outcome ,chemistry ,Distilled water ,Female ,Stearic acid ,medicine.drug - Abstract
Solid Lipid Nanoparticles (SLN) containing Methotrexate (MTX), an anticancer drug for intravenous administration was formulated and characterized. The SLN dispersions with MTX, stearic acid, and soya lecithin in the ratio of 1:4:1, 1:4:1.5, and 1:4:2, sodium taurodeoxycholate and distilled water were prepared by micro emulsification solidification method. The results show that the prepared MTX-SLN particles (with MTX–Stearic acid–Soya lecithin—1:4:2) have an average size of 270 nm with 51.3% drug entrapment. The in vitro-release was attained up to 15th h. The pharmacokinetic studyreveals that the half-life and MRT of SLNs were higher than MTX solution. The life span of EAC (Ehrlich Ascite Carcinoma) bearing mice was increased when treated with MTX-SLNs (Methotrexate nanoparticles). These results clearly indicate that SLNs are a promising sustained release drug targeting system for lipophilic antitumour drugs.
- Published
- 2006
50. Correlation between acoustic cavitation noise and yield enhancement of sonochemical reaction by particle addition
- Author
-
Yasuo Iida, Toru Tuziuti, Manickam Sivakumar, Norio Miyoshi, and Kyuichi Yasui
- Subjects
Chemical Phenomena ,Chemistry ,Chemistry, Physical ,Physics::Medical Physics ,Analytical chemistry ,Temperature ,Sound intensity ,Sonochemistry ,Physics::Fluid Dynamics ,Absorbance ,Noise ,Yield (chemistry) ,Cavitation ,Particle ,Ultrasonics ,Irradiation ,Physical and Theoretical Chemistry ,Particle Size - Abstract
The mechanism of the effect of particle addition on sonochemical reaction is studied through the measurements of frequency spectrum of sound intensity for evaluating the cavitation noise and the absorbance for the liberation of iodine from an aqueous solution of KI as an index of oxidation reaction by ultrasonic irradiation in the presence or absence of alumina particles. As it is expected that both the acoustic noise and a rise in temperature in the liquid irradiated by intense ultrasound will increase with the number of collapsing bubbles, these are supposed to be the best tools for evaluating the relative number of bubbles. In the present investigation, it has been shown that the addition of particles with appropriate amount and size results in an increase in the absorbance when both the acoustic noise and the rise in the liquid temperature due to cavitation bubbles also increase. This suggests that the enhancement in the yield of sonochemical reaction by appropriate particle addition comes from an increase in the number of cavitation bubbles. The existence of particle in liquid provides a nucleation site for cavitation bubble due to its surface roughness, leading to the decrease in the cavitation threshold responsible for the increase in the number of bubbles when the liquid is irradiated by ultrasound. Thus, from the present investigation, it is clarified that the particle addition has a potential to enhance the yield in the sonochemical reaction.
- Published
- 2006
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.