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3. Tanshinone IIA enhances the ovarian reserve and attenuates ovarian oxidative stress in aged mice

Author

Lin Bai, Guozhen He, Chenghai Gao, Hua Yang, Mingxing Li, Yulin Huang, Mahmoud Moussa, and Changlong Xu

Subjects
Anti-Mullerian Hormone, Mice, Oxidative Stress, General Veterinary, NF-E2-Related Factor 2, Abietanes, Animals, Follicle Stimulating Hormone, Ovarian Reserve, Antioxidants
Abstract

Tanshinone IIA (TSA), a major lipophilic component extracted from the roots of Salvia miltiorrhiza Bunge, has been widely used in China for its various biological activities. However, its effect on ovarian reserve in aged mice was not studied elsewhere.This study aimed to explore the effect of TSA on the ovarian reserve of aged mice as well as young mice. Forty weeks old mice (N = 40) were considered as aged group compared to 4 weeks old mice (N = 40), and these groups were subdivided into four subgroups (N = 10) to receive different doses of TSA (0, 10, 20, and 40 μg/g/day).The effect of TSA was evaluated by counting follicular number by histological examination. Basal serum levels of FSH, LH, E2, and anti-Mullerian hormone (AMH) were measured by ELISA. Moreover, the expression levels of antioxidant genes (CAT, Nrf2, GPX1), gap junction (Cx37), ERK1/2, and Smad5 family gene were examined at both mRNA (qPCR) and protein levels (western blot).Follicular number, level of AMH and E2, and the expression of CAT, Nrf2, and GPX1 genes increased significantly (p 0.05) in aged mice administrated with medium (20 μg/g/day) and high (40 μg/g/day) doses of TSA, whereas FSH and LH levels were significantly low compared to low dose (10 μg/g/day) and control (0 μg/g/day) aged subgroups. However, we did not observe any effect of all doses of TSA on young mice.Administration of TSA with medium and high doses up-regulates the expression of antioxidative genes, reduces the oxidative injury, increases levels of AMH, and E2 levels that are relatively comparable to those in young mice, and consequently results in a healthy oocyte development.

Published
2022
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5. Potentially inadequate medications in the elderly: PRISCUS 2.0—first update of the PRISCUS list

Author

Nina-Kristin Mann, Tim Mathes, Andreas Sönnichsen, Dawid Pieper, Elisabeth Klager, Mahmoud Moussa, and Petra A. Thürmann

Subjects
Original Article, General Medicine
Abstract

BACKGROUND: The term potentially inadequate medication (PIM) is used to describe substances that may be unsuitable for use in the elderly and should be avoided. The PRISCUS list, published in 2010, was the first catalog of PIM designed for the German drug market to become adopted in practice. While 24% of German patients aged ≥ 65 years were prescribed at least one PIM per year in 2009, the proportion in 2019 was only 14.5%. METHODS: In a three-round Delphi process, experts from clinical practice and research evaluated whether selected substances are PIM for the elderly. The participants were provided with dedicated literature including systematic reviews carried out for the particular purposes of this project. RESULTS: Fifty-nine persons took part in the Delphi process and, in addition, contributed comments and therapeutic alternatives. Altogether, 187 substances were classed as PIM. One hundred thirty-three of the substances now listed were not in the original PRISCUS list: these include some oral antidiabetics, all of the selective COX-2 inhibitors, and moderately long acting benzodiazepines such as oxazepam. For some other substances, e.g., proton pump inhibitors (PPI), the advisability of treatment for more than 8 weeks was considered as potentially inappropriate, as was the use of ibuprofen in doses >1200 mg/day and for more than 1 week without PPI. Risperidone for more than 6 weeks is also PIM. CONCLUSION: The new, greatly extended PRISCUS list must now be validated in epidemiological and prospective studies and its practicability in routine daily use must be verified.

Published
2023
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6. Psychometric Characteristics of Verbal Working Memory Scale among Savant Syndrome Children

Author

Hisham Ibrahim Ismael Elnersh and Mahmoud Moussa

Subjects
Working memory, Working Memory Scale, medicine, Savant syndrome, Autism, medicine.disease, Psychology, Special education, Exploratory factor analysis, Confirmatory factor analysis, Clinical psychology, Test (assessment)
Abstract

The study aimed to construct a test for the behavioral implications of verbal working memory among Savant syndrome and Verify the factor structure of the test using factor analysis. The study relied on the Geweke & Singleton (1980) approach to select the participants. The study sample consisted of a targeted sample with Savant syndrome. 32 Savant syndrome cases had selected. The verbal working memory test was applied electronically with the help of four colleagues in the field of special education. The applying procedure lasted nine months. The Exploratory Factor Analysis results reached a fitted general factor model. The confirmatory analysis results revealed the fitted construct of the first-order three-factor model structure. The results indicated the possibility of the three-factors loading on a second-order general factor structure. Keywords: Autism; Savant syndrome; Verbal working memory.

Published
2021
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7. Vonoprazan-Based versus Esomeprazole-Based Triple Therapy for Helicobacter Pylori, a Randomized Trial

Author

Yasser Abdelghani and Mahmoud Moussa

Abstract

Background: Vonoprazan-based regimens are anticipated to have higher Helicobacter pylori eradication rates than PPIs. Aim and objective: to compare between the effectiveness of two 14-day regimens; one based on vonoprazan and the other on esomeprazole, to eradicate H. pylori. Patients and methods: Participants were determined to have active H. pylori infection and were either untreated or had previously received therapy were randomly assigned to either the VAL group (vonoprazan 20 mg bid, amoxicillin 1000 mg bid, plus levofloxacin 500 mg once day) or the EAL group (Esomeprazole 20 mg bid., amoxicillin 1000 mg bid., and levofloxacin 500 mg once daily). After 4-6 weeks following the end of the therapy, an H. pylori antigen test was used to determine the degree of eradication. Results: A number of 122 individuals were randomly assigned to either the VAL (n = 61) or EAL (n = 61) groups, and 118 patients were successful in completing the study. The eradication rates of H. pylori were found to be 97.7 percent for the VAL group and 68.5 percent for the EAL group, respectively (P = 0.031). All adverse treatment-related occurrences were minor and did not differ substantially between the two groups, such as nausea and vertigo. Conclusions: The VAL regimen was well tolerated and led to increased eradication rates; as a result, VAL may be thought of as a powerful regimen for treating H. pylori, particularly in nations with high levels of antibiotic resistance.

Published
2022
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9. إستراتيجيات المعايشة مع جائحة فيروس كورونا المستجد (COVID-19) في المجتمع العربي

Author

Dahmane Yahia Souici, Mahmoud Moussa, and Abdel-Nasser El-Sayed Amer

Subjects
Immunology
Abstract

هدفت الدراسة إلى تحديد مستويات إستراتيجيات المعايشة الحياتية والفروق بين الجنسين والفروق بين المتزوجين وغير المتزوجين في إستراتيجيات المعايشة مع جائحة كورونا في المجتمع العربي. واعتمدت هذه الدراسة الوصفية على منهج المسح الاجتماعي بالعينة؛ حيث اختيرت عينة الدراسة بطريقة كرة الثلج، وتكونت من 303 مشاركين، ممن تتراوح أعمارهم بين 13 إلى 81 عامًا، وصممت قائمة بإستراتيجيات المعايشة مع جائحة كورونا. وقد توصلت الدراسة إلى أن 62.34% التزموا بالتعليمات والإجراءات الاحترازية، والتزم 71.03% بالجوانب الدينية، والتزم 43.7% بالتباعد الاجتماعي، في حين التزم 61.7% بالجوانب النفسية المعتدلة للتعامل مع الجائحة. وتفوقت الإناث في إستراتيجيات الصلاة وعدم المصافحة، وإستراتيجية التوجه إلى الله والتباعد الاجتماعي، وتجنب الأماكن المزدحمة. كما بيّنت النتائج وجود علاقة ارتباطية سالبة بين العمر والبقاء في المنزل. وعليه أوصت الدراسة بضرورة توافر العوامل المساعدة في التعايش مع وضعية الموجة الثانية لفيروس كورونا المستجد، مثل: الضغط المدرك مقابل إستراتيجيات المعايشة، والسلوكيات غير الصحية مقابل الإدراك غير المشوه للوضع، وانخفاض الحرية مقابل تلقي دعم نفسـي اجتماعي جيد، وانخفاض المقاومة مقابل التواصل غير المشوه مع الذات، وشعور عدم الأمان مقابل التواصل مع الله، مع العمل على التوعية الإعلامية الموجهة لدور رجال الأمن والأطقم الطبية، ونبذ العنف، والمساعدة على التعايش بصورة أكثر توافقية.

Published
2021
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22. Search for resonances decaying to three W bosons in the hadronic final state in proton-proton collisions at s=13 TeV

Author

Viacheslav Bunichev, Mikko Voutilainen, Jordan Nash, Dmitry Kondratyev, Francisco Garcia, Raghunath Pradhan, Gabriella Pugliese, Alberto Escalante del Valle, Praveen Chandra Tiwari, Mate Csanad, Kadir Saygin, Kenneth Bloom, Pietro Govoni, Maximilian Pérez Prada, Arie Bodek, Riccardo Salvatico, Mikhail Dubinin, Andrea Cardini, Chang-Seong Moon, Ted Kolberg, Guenakh Mitselmakher, Kun Shi, Caglar Zorbilmez, Lorenzo Viliani, Ankush Reddy Kanuganti, Wesley Smith, Mikael Myllymäki, Walaa Elmetenawee, Erhan Gülmez, Giovanni Abbiendi, Fabrizio Palla, Valentina Sola, Matthias Schröder, Cristina Riccardi, Johan Borg, Sami Lehti, Abanti Ranadhir Sahasransu, Joseph Reichert, Jussi Viinikainen, Badder Marzocchi, Luke Kreczko, Hugues Lattaud, FLAVIA CETORELLI, Georgios Konstantinos Krintiras, Samet Lezki, Stefano Belforte, Maria Savina, Reza Goldouzian, Márton Bartók, Daniele Fasanella, Erika Garutti, Louis Moureaux, Nadia Pastrone, Danyer Pérez Adán, Muhammad Ahmad, Konstantin Androsov, Toni Sculac, Arun Kumar, Andreas Pfeiffer, Jorge Berenguer Antequera, Giuseppe Della Ricca, Eduard De La Cruz Burelo, Joern Schwandt, Christopher Tully, Luigi Calligaris, Wael HAJ AHMAD (Vael HAJAHMAD), Jennifer Ott, Francisco Javier Cuevas Maestro, Steffen Albrecht, Pablo Matorras-Cuevas, Prabhat Ranjan Pujahari, Alessandra Cappati, Alexander Belyaev, Florian Bury, Roman Kogler, Andrea Giammanco, Marco Toliman Lucchini, Guenther Dissertori, Francesca Cavallari, José María Hernández Calama, Efe Yazgan, Nils Faltermann, Yuri Gershtein, Sinan Sagir, Tomas Lindén, Halil Saka, Luca Cadamuro, Florencia Canelli, Simone Pigazzini, Armando Bermudez Martinez, Dmitri Konstantinov, Ksenia Shchelina, Cesar Augusto Bernardes, Bingran Wang, Qiang Li, Nicolò Trevisani, Tapio Lampén, Md Naimuddin, Barry Blumenfeld, Leonid Levchuk, Claudio Grandi, Giovanni Petrucciani, Dayong Wang, Marco Zanetti, Cristina Botta, Danilo Meuser, Martti Raidal, John Conway, Jaime Leon Holgado, Paolo Giacomelli, Jay R. Dittmann, Yalcin Guler, Agni Bethani, Marcin Konecki, Franco Ligabue, Alexander Grohsjean, Lourdes Urda, Mahmoud Moussa Abdelkhalek Gadallah, Silvano Tosi, Martina Malberti, Merve Ince Lezki, Jochen Schieck, Leonardo Cristella, Ernesto Migliore, Pritam Kalbhor, Silvia Goy Lopez, Ashish Sharma, Tommaso Diotalevi, Nikolaos Manthos, Lisa Benato, Suman Chatterjee, Émilien Chapon, JUAN ALCARAZ MAESTRE, Antonio Vilela Pereira, Álvaro Navarro-Tobar, Thong Q. Nguyen, Zhenbin Wu, Maria Clemencia Mora Herrera, Zhengyun You, Agostino De Iorio, Ilaria Vai, Gilvan Alves, Sandeep Bhowmik, Cristina Fernández Bedoya, Nabin Poudyal, Markus Seidel, Andre Sznajder, Ali Eren Simsek, Tamer Elkafrawy, Pedro Galli Mercadante, Kenyi Hurtado Anampa, Luca Giommi, Efe Yigitbasi, Andrea Massironi, Andrey Starodumov, Jose Ruiz, Mario Pelliccioni, Caroline Collard, Alexei Safonov, WILLIAM FORD, Junghwan Goh, Spandan Mondal, Jingyan Li, German Ruben Martinez, Walter Snoeys, Evgueni Tcherniaev, Matteo Presilla, Stephen Mrenna, Jeremy Andrea, Panja Luukka, Saranya Samik Ghosh, Rogelio Reyes-Almanza, Joachim Mnich, Sandor Lokos, Darin Acosta, Karl Ehatäht, Aurelijus Rinkevicius, Frank Geurts, Isabel Josa Mutuberria, Junquan Tao, Paul Kyberd, Ece ASILAR, David D'Enterria, Daniel Savoiu, Francesco Fienga, Jay Lawhorn, Arabella Martelli, Robert Cousins, Santeri Laurila, Jorma Tuominiemi, Andrey Popov, Jehad Mousa, Martin Grunewald, Paolo Spagnolo, Nicholas Wardle, Redwan Habibullah, Robert Klanner, Frank Golf, Isidro González Caballero, Crisostomo Sciacca, Oscar Gonzalez Lopez, Tahys Janssen, Jeremi Niedziela, Robert Bainbridge, Elizabeth Starling, Andrea Rizzi, Javier Alberto Murillo Quijada, Klaus Rabbertz, Luigi (Gigi) Rolandi, Federica Legger, Andrew Ivanov, ANKITA MEHTA, Ioannis Papadopoulos, Greg Landsberg, Malte Backhaus, Aliakbar Ebrahimi, INSEOK YOON, Sara Fiorendi, ANDREA PICCINELLI, Dmitry Kirpichnikov, Jennifer Ngadiuba, Tamas Almos Vami, Ivan Heredia de la Cruz, Maciej Malawski, Vuko Brigljević, Thomas McCauley, Vittorio Raoul Tavolaro, Pablo Martinez Ruiz del Arbol, Davide Fiorina, Kaur Sandeep, Reddy Pratap Gandrajula, Luca Malgeri, Leszek Grzanka, Peter Elmer, Lea Caminada, Kenneth Osterberg, Leandar Litov, Lata Panwar, Zhicai Zhang, Anton Stepennov, Arnd Meyer, Tatyana Dimova, Christophe Ochando, Alberto Ruiz Jimeno, J B Singh, Johannes Lange, Peter Wittich, Maria Cruz Fouz Iglesias, Korbinian Schweiger, Gaetano Marco Dallavalle, Pietro Faccioli, Rafael Eduardo Sosa Ricardo, Avi Yagil, Muhammad Gul, Jaana Heikkilä, Arne Christoph Reimers, Michele Arneodo, José Flix Molina, Javier Fernandez Menendez, Alexander Tapper, Valeria D'Amante, Sandra S. Padula, George Alverson, Lev Dudko, Juan Pablo Fernández Ramos, Karl Ecklund, Salvatore Costa, Yacine Haddad, Carlos Eugenio Perez Lara, Paolo Meridiani, Ignacio Redondo, Marco Monteno, Gautier Hamel de Monchenault, Salvatore Rappoccio, Gerrit Van Onsem, Thomas Reis, Anna Colaleo, Marco CUFFIANI, Torben Lange, Lutz Feld, Varun Sharma, Gabriella Pásztor, Nicolas Stylianou, Sung-Won Lee, Joel Goldstein, Daniel Diaz, Paolo Azzurri, Oleg Filatov, Welathantri Dharmaratna, ÜMİT SÖZBİLİR, Davide Zuolo, Ram Krishna Sharma, Ian Watson, Javier Mauricio Duarte, Vilius Cepaitis, Andreas Hinzmann, Nikkie Deelen, Matthias Kasemann, Manfred Paulini, Paolo Dini, Andre Frankenthal, Kevin Lannon, Mithat Kaya, Florian Beaudette, Barbara Alvarez Gonzalez, Nuno Leonardo, Maxim Titov, Laurent Forthomme, Jose Enrique Palencia Cortezon, Rainer Wallny, Pietro Vischia, Schoefbeck Robert, Thea Aarrestad, Gaia Grosso, Pieter David, Liuyao Zhang, Tae Jeong Kim, Marco Pieri, Sunil Manohar Dogra, Shabnam Jabeen, Guido Emilio Tonelli, Mar Capeans, Davide Di Croce, Ugur Kiminsu, J.F. Benitez, Luiz Mundim, Jason Lee, Maria Cepeda, Pallabi Das, Ksenia De Leo, Deborah Pinna, Morgan Lethuillier, Soureek Mitra, Bruno Lenzi, Sergio Novaes, Antonio Delgado Peris, Amina Zghiche, Pieter Everaerts, Gurpreet Singh Chahal, Hannu Siikonen, Mohammed Attia Mahmoud, André David Tinoco Mendes, Olga Evdokimov, Pierluigi Bortignon, Shubhanshu Chauhan, Simone Gennai, Freya Blekman, Furkan Dolek, Umberto Dosselli, Federica Maria Simone, Raffaele Gerosa, Benjamin Krikler, Geoffrey Hall, Eija Tuominen, Marko Dragicevic, Antonio Perez-Calero Yzquierdo, Nadezda Chernyavskaya, Mykhailo Dalchenko, Joona Juhani Havukainen, Biagio Rossi, Ibrahim Soner Zorbakir, Sandra Consuegra Rodriguez, Roberto Covarelli, Chiara Amendola, Christophorus Grab, Mojtaba Mohammadi Najafabadi, Henning Flaecher, Dilson De Jesus Damiao, Arthur Moraes, Lucas Taylor, Graham Wilson, Rui Xiao, Minsuk Kim, Alberto Sanchez-Hernandez, Tobias Robert Jakob Kramer, Marino Missiroli, Jan-Frederik Schulte, Fotios Ptochos, Shudhashil Bharthuar, Justin Williams, Helen Heath, Wolfgang Waltenberger, Henning Kirschenmann, Hannes Jung, Emrah Tiras, Camilo Carrillo Montoya, Yu Zhang, Alberto Zucchetta, Ralf Ulrich, Calandri Alessandro, Tahereh Sadat Niknejad, Guillelmo Gomez-Ceballos, Felipe Araujo, Kadri Ozdemir, Patrizia Azzi, Muhammad Alibordi, Vladimir Gavrilov, Johannes Haller, Kati Lassila-Perini, Abhijith Gandrakota, Konstantinos Theofilatos, Gouranga Kole, Eliza Melo da Costa, Andrea Davide Benaglia, Sebastian Wuchterl, Jesus Puerta Pelayo, Laura Martikainen, Ram Krishna Dewanjee, Christophe Delaere, Simon Regnard, Aaron Dominguez, Emanuele Usai, Matthew Herndon, Kenichi Hatakeyama, LUCA GUZZI, Alberto Belloni, Harrison Bertrand Prosper, Federico Siviero, Mariana Shopova, Mauro Donega, Abideh Jafari, Antonio Cassese, Federico De Guio, UTTIYA SARKAR, Aashaq Shah, Oliver Gutsche, Claudio Caputo, Mauro Emanuele Dinardo, Elisabetta Manca, Amedeo Staiano, Soumya Mukherjee, Thiago Rafael Fernandez Perez Tomei, Sudhir Malik, Clemens Lange, and Bożena Boimska

Published
2022
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23. Search for Resonances Decaying to Three W Bosons in Proton-Proton Collisions at s=13 TeV

Author

Viacheslav Bunichev, Mikko Voutilainen, Stefaan Tavernier, Jordan Nash, Francisco Garcia, Raghunath Pradhan, Gabriella Pugliese, Alberto Escalante del Valle, Praveen Chandra Tiwari, Mate Csanad, Kadir Saygin, Kenneth Bloom, Pietro Govoni, Maximilian Pérez Prada, Arie Bodek, Riccardo Salvatico, Mikhail Dubinin, Andrea Cardini, Chang-Seong Moon, Ted Kolberg, Guenakh Mitselmakher, Kun Shi, Caglar Zorbilmez, Lorenzo Viliani, Ankush Reddy Kanuganti, Wesley Smith, Mikael Myllymäki, Hesham El Faham, Walaa Elmetenawee, Erhan Gülmez, Giovanni Abbiendi, Fabrizio Palla, Valentina Sola, Matthias Schröder, Cristina Riccardi, Sami Lehti, Abanti Ranadhir Sahasransu, Joseph Reichert, Jussi Viinikainen, Badder Marzocchi, Luke Kreczko, Hugues Lattaud, FLAVIA CETORELLI, Georgios Konstantinos Krintiras, Samet Lezki, Stefano Belforte, Maria Savina, Reza Goldouzian, Márton Bartók, Daniele Fasanella, Erika Garutti, Shalini Thakur, Louis Moureaux, Nadia Pastrone, Danyer Pérez Adán, Muhammad Ahmad, Konstantin Androsov, Toni Sculac, Arun Kumar, Andreas Pfeiffer, Jorge Berenguer Antequera, Giuseppe Della Ricca, Eduard De La Cruz Burelo, Joern Schwandt, Christopher Tully, Luigi Calligaris, Wael HAJ AHMAD (Vael HAJAHMAD), Jennifer Ott, Francisco Javier Cuevas Maestro, Steffen Albrecht, Pablo Matorras-Cuevas, Prabhat Ranjan Pujahari, Alessandra Cappati, Alexander Belyaev, Florian Bury, James Buchanan, Roman Kogler, Andrea Giammanco, Marco Toliman Lucchini, Guenther Dissertori, Francesca Cavallari, José María Hernández Calama, Antonello Pellecchia, Efe Yazgan, Nils Faltermann, Yuri Gershtein, Sinan Sagir, Tomas Lindén, Halil Saka, Luca Cadamuro, Florencia Canelli, Simone Pigazzini, Armando Bermudez Martinez, Dmitri Konstantinov, Ksenia Shchelina, Cesar Augusto Bernardes, Bingran Wang, Qiang Li, Nicolò Trevisani, Tapio Lampén, Md Naimuddin, Barry Blumenfeld, Leonid Levchuk, Claudio Grandi, Giovanni Petrucciani, Dayong Wang, Marco Zanetti, Cristina Botta, Danilo Meuser, Martti Raidal, John Conway, Jaime Leon Holgado, Paolo Giacomelli, Jay R. Dittmann, Yalcin Guler, Agni Bethani, Marcin Konecki, Franco Ligabue, Alexander Grohsjean, Lourdes Urda, Mahmoud Moussa Abdelkhalek Gadallah, Silvano Tosi, Martina Malberti, Merve Ince Lezki, Jochen Schieck, Leonardo Cristella, Ernesto Migliore, Pritam Kalbhor, Silvia Goy Lopez, Ashish Sharma, Tommaso Diotalevi, Nikolaos Manthos, Lisa Benato, Suman Chatterjee, Émilien Chapon, JUAN ALCARAZ MAESTRE, Antonio Vilela Pereira, Álvaro Navarro-Tobar, Thong Q. Nguyen, Zhenbin Wu, Maria Clemencia Mora Herrera, Zhengyun You, Agostino De Iorio, Ilaria Vai, Gilvan Alves, Sandeep Bhowmik, Cristina Fernández Bedoya, Nabin Poudyal, Markus Seidel, Andre Sznajder, Ali Eren Simsek, Tamer Elkafrawy, Pedro Galli Mercadante, Kenyi Hurtado Anampa, Luca Giommi, Efe Yigitbasi, Andrea Massironi, Andrey Starodumov, Jose Ruiz, Mario Pelliccioni, Caroline Collard, Alexei Safonov, WILLIAM FORD, Junghwan Goh, Spandan Mondal, Jingyan Li, German Ruben Martinez, Walter Snoeys, Evgueni Tcherniaev, Matteo Presilla, Stephen Mrenna, Jeremy Andrea, Panja Luukka, Saranya Samik Ghosh, Rogelio Reyes-Almanza, Joachim Mnich, Sandor Lokos, Darin Acosta, Karl Ehatäht, Aurelijus Rinkevicius, Frank Geurts, Isabel Josa Mutuberria, Junquan Tao, Paul Kyberd, Ece ASILAR, David D'Enterria, Sergey Polikarpov, Daniel Savoiu, Adish Vartak, Francesco Fienga, Jay Lawhorn, Arabella Martelli, Robert Cousins, Santeri Laurila, Jorma Tuominiemi, Andrey Popov, Jehad Mousa, Martin Grunewald, Paolo Spagnolo, Nicholas Wardle, Redwan Habibullah, Robert Klanner, Frank Golf, Isidro González Caballero, Crisostomo Sciacca, Oscar Gonzalez Lopez, Tahys Janssen, Jeremi Niedziela, Robert Bainbridge, Elizabeth Starling, Andrea Rizzi, Javier Alberto Murillo Quijada, Klaus Rabbertz, Luigi (Gigi) Rolandi, Federica Legger, Andrew Ivanov, ANKITA MEHTA, Ioannis Papadopoulos, Greg Landsberg, Malte Backhaus, Aliakbar Ebrahimi, INSEOK YOON, Sara Fiorendi, ANDREA PICCINELLI, Dmitry Kirpichnikov, Jennifer Ngadiuba, Tamas Almos Vami, Ivan Heredia de la Cruz, Maciej Malawski, Vuko Brigljević, Thomas McCauley, Vittorio Raoul Tavolaro, Pablo Martinez Ruiz del Arbol, Davide Fiorina, Kaur Sandeep, Reddy Pratap Gandrajula, Luca Malgeri, Leszek Grzanka, Peter Elmer, Lea Caminada, Kenneth Osterberg, Emil Sørensen Bols, Leandar Litov, Lata Panwar, Zhicai Zhang, Anton Stepennov, Arnd Meyer, Tatyana Dimova, Christophe Ochando, Alberto Ruiz Jimeno, J B Singh, Johannes Lange, Peter Wittich, Maria Cruz Fouz Iglesias, Korbinian Schweiger, Gaetano Marco Dallavalle, Pietro Faccioli, Rafael Eduardo Sosa Ricardo, Avi Yagil, Muhammad Gul, Jaana Heikkilä, Arne Christoph Reimers, Michele Arneodo, José Flix Molina, Javier Fernandez Menendez, Alexander Tapper, Valeria D'Amante, Sandra S. Padula, George Alverson, Lev Dudko, Juan Pablo Fernández Ramos, Karl Ecklund, Martin Delcourt, Salvatore Costa, Yacine Haddad, Paolo Meridiani, Ignacio Redondo, Marco Monteno, Gautier Hamel de Monchenault, Salvatore Rappoccio, Gerrit Van Onsem, Bora Akgun, Thomas Reis, Anna Colaleo, Marco CUFFIANI, Torben Lange, Lutz Feld, Varun Sharma, Gabriella Pásztor, Nicolas Stylianou, Sung-Won Lee, Joel Goldstein, Daniel Diaz, Paolo Azzurri, Oleg Filatov, Welathantri Dharmaratna, Benedikt Vormwald, Davide Zuolo, Ram Krishna Sharma, Ian Watson, Javier Mauricio Duarte, Vilius Cepaitis, Andreas Hinzmann, Nikkie Deelen, Matthias Kasemann, Manfred Paulini, Paolo Dini, Andre Frankenthal, Kevin Lannon, Mithat Kaya, Myriam Schönenberger, Florian Beaudette, Barbara Alvarez Gonzalez, Nuno Leonardo, Maxim Titov, Laurent Forthomme, Jose Enrique Palencia Cortezon, Rainer Wallny, Pietro Vischia, Schoefbeck Robert, Thea Aarrestad, Pieter David, Liuyao Zhang, Tae Jeong Kim, Marco Pieri, Sunil Manohar Dogra, Shabnam Jabeen, Guido Emilio Tonelli, Mar Capeans, Davide Di Croce, Ugur Kiminsu, J.F. Benitez, Luiz Mundim, Jason Lee, Jorgen D'Hondt, Maria Cepeda, Pallabi Das, Ksenia De Leo, Deborah Pinna, Morgan Lethuillier, Soureek Mitra, Bruno Lenzi, Sergio Novaes, Antonio Delgado Peris, Amina Zghiche, Pieter Everaerts, Gurpreet Singh Chahal, Hannu Siikonen, Mohammed Attia Mahmoud, André David Tinoco Mendes, Olga Evdokimov, Pierluigi Bortignon, Shubhanshu Chauhan, Simone Gennai, Freya Blekman, Furkan Dolek, Federica Maria Simone, Raffaele Gerosa, Benjamin Krikler, Geoffrey Hall, Eija Tuominen, Marko Dragicevic, Antonio Perez-Calero Yzquierdo, Nadezda Chernyavskaya, Mykhailo Dalchenko, Joona Juhani Havukainen, Biagio Rossi, Ibrahim Soner Zorbakir, Sandra Consuegra Rodriguez, Roberto Covarelli, Chiara Amendola, Christophorus Grab, Mojtaba Mohammadi Najafabadi, Henning Flaecher, Dilson De Jesus Damiao, Arthur Moraes, Lucas Taylor, Graham Wilson, Rui Xiao, Minsuk Kim, Alberto Sanchez-Hernandez, Tobias Robert Jakob Kramer, Marino Missiroli, Jan-Frederik Schulte, Fotios Ptochos, Shudhashil Bharthuar, Justin Williams, Helen Heath, Wolfgang Waltenberger, Henning Kirschenmann, Hannes Jung, Emrah Tiras, Camilo Carrillo Montoya, Alberto Zucchetta, Ralf Ulrich, Calandri Alessandro, Tahereh Sadat Niknejad, Guillelmo Gomez-Ceballos, Felipe Araujo, Kadri Ozdemir, Patrizia Azzi, Muhammad Alibordi, Vladimir Gavrilov, Johannes Haller, Kati Lassila-Perini, Abhijith Gandrakota, Konstantinos Theofilatos, Gouranga Kole, Eliza Melo da Costa, Andrea Davide Benaglia, Sebastian Wuchterl, Jesus Puerta Pelayo, Laura Martikainen, Ram Krishna Dewanjee, Christophe Delaere, Simon Regnard, Aaron Dominguez, Emanuele Usai, Matthew Herndon, Kenichi Hatakeyama, LUCA GUZZI, Alberto Belloni, Harrison Bertrand Prosper, Federico Siviero, Mariana Shopova, Mauro Donega, Abideh Jafari, Antonio Cassese, Federico De Guio, UTTIYA SARKAR, Aashaq Shah, Oliver Gutsche, Claudio Caputo, Mauro Emanuele Dinardo, Elisabetta Manca, Amedeo Staiano, Soumya Mukherjee, Thiago Rafael Fernandez Perez Tomei, Sudhir Malik, Clemens Lange, and Bożena Boimska

Subjects
General Physics and Astronomy
Published
2022
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24. Autogenous Dentin Block of a Non‐Restorable Wisdom Tooth for Localized Horizontal Ridge Augmentation: Radiographic and Histological Analysis – A Preliminary Case Report

Author

Leila Elraee, Doaa Adel-Khattab, and Mahmoud Moussa

Subjects
Orthodontics, 050402 sociology, Osteosynthesis, business.industry, medicine.medical_treatment, 05 social sciences, General Engineering, 030206 dentistry, General Medicine, Alveolar Ridge Augmentation, Mandibular first molar, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, stomatognathic system, 0504 sociology, medicine, Cortical bone, Implant, Wisdom tooth, Dental implant, business, Fixation (histology)
Abstract

Introduction Tooth roots proved in different studies clinically and radiographically to be an alternative to autogenous bone. However, the histological evaluation of the tooth block following ridge augmentation is still missing. The aim of this case report was to evaluate histologically and radiographically the effect of autogenous dentin block (DB) to restore a horizontal ridge deficiency at a single tooth gap. Case presentation A healthy 36-years old female patient presented with a missing lower first molar (30), after clinical and radiographic examination, the site showed a class III defect horizontal atrophy. The procedure performed was the surgical removal of the wisdom tooth (32), shaping and fixation of a separated DB at the defect site using an osteosynthesis screw. A cone beam computed tomography was performed immediately and 6 month following the surgery. During implant placement, a core biopsy specimen was retrieved, stored and prepared for histological evaluation. The radiographic analysis showed a horizontal width gain of about 4 mm. The histologic assessment revealed cortical bone formation at the buccal and lingual aspects between the tooth and the bone. During implant placement, the core biopsy exhibited a slight separation upon removal from the grafted side, at 6 month following implant placement, the implant was successfully osteointegrated. Conclusion DB was successfully used for horizontal alveolar ridge augmentation, thus allowing a prosthetically driven implant placement. More cases assessing implant survival and success are needed to confirm the results of this case report.

Published
2020
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25. Measurement of the production cross section for Z+b jets in proton-proton collisions at s=13 TeV

Author

Mikko Voutilainen, Stefaan Tavernier, Jordan Nash, Dmitry Kondratyev, Francisco Garcia, Raghunath Pradhan, Gabriella Pugliese, Alberto Escalante del Valle, Praveen Chandra Tiwari, Mate Csanad, Kadir Saygin, Kenneth Bloom, Pietro Govoni, Maximilian Pérez Prada, Arie Bodek, Riccardo Salvatico, Mikhail Dubinin, Andrea Cardini, Chang-Seong Moon, Ted Kolberg, Guenakh Mitselmakher, Kun Shi, Caglar Zorbilmez, Lorenzo Viliani, Ankush Reddy Kanuganti, Wesley Smith, Mikael Myllymäki, Hesham El Faham, Walaa Elmetenawee, Erhan Gülmez, Giovanni Abbiendi, Fabrizio Palla, Valentina Sola, Matthias Schröder, Cristina Riccardi, Sami Lehti, Abanti Ranadhir Sahasransu, Joseph Reichert, Jussi Viinikainen, Badder Marzocchi, Luke Kreczko, Hugues Lattaud, FLAVIA CETORELLI, Georgios Konstantinos Krintiras, Samet Lezki, Stefano Belforte, Maria Savina, Reza Goldouzian, Márton Bartók, Daniele Fasanella, Erika Garutti, Louis Moureaux, Nadia Pastrone, Danyer Pérez Adán, Muhammad Ahmad, Konstantin Androsov, Toni Sculac, Arun Kumar, Andreas Pfeiffer, Jorge Berenguer Antequera, Giuseppe Della Ricca, Eduard De La Cruz Burelo, Joern Schwandt, Christopher Tully, Luigi Calligaris, Wael HAJ AHMAD (Vael HAJAHMAD), Jennifer Ott, Francisco Javier Cuevas Maestro, Steffen Albrecht, Pablo Matorras-Cuevas, Prabhat Ranjan Pujahari, Alessandra Cappati, Alexander Belyaev, Florian Bury, Roman Kogler, Andrea Giammanco, Marco Toliman Lucchini, Guenther Dissertori, Francesca Cavallari, José María Hernández Calama, Efe Yazgan, Nils Faltermann, Yuri Gershtein, Sinan Sagir, Tomas Lindén, Halil Saka, Luca Cadamuro, Florencia Canelli, Simone Pigazzini, Armando Bermudez Martinez, Dmitri Konstantinov, Ksenia Shchelina, Cesar Augusto Bernardes, Bingran Wang, Qiang Li, Richard Breedon, Nicolò Trevisani, Tapio Lampén, Md Naimuddin, Barry Blumenfeld, Leonid Levchuk, Claudio Grandi, Giovanni Petrucciani, Dayong Wang, Marco Zanetti, Cristina Botta, Danilo Meuser, Martti Raidal, John Conway, Jaime Leon Holgado, Paolo Giacomelli, Jay R. Dittmann, Yalcin Guler, Agni Bethani, Marcin Konecki, Franco Ligabue, Alexander Grohsjean, Lourdes Urda, Mahmoud Moussa Abdelkhalek Gadallah, Silvano Tosi, Martina Malberti, Merve Ince Lezki, Jochen Schieck, Leonardo Cristella, Ernesto Migliore, Pritam Kalbhor, Silvia Goy Lopez, Ashish Sharma, Tommaso Diotalevi, Nikolaos Manthos, Lisa Benato, Suman Chatterjee, Émilien Chapon, JUAN ALCARAZ MAESTRE, Antonio Vilela Pereira, Álvaro Navarro-Tobar, Thong Q. Nguyen, Zhenbin Wu, Maria Clemencia Mora Herrera, Zhengyun You, Agostino De Iorio, Ilaria Vai, Gilvan Alves, Sandeep Bhowmik, Cristina Fernández Bedoya, Nabin Poudyal, Markus Seidel, Andre Sznajder, Ali Eren Simsek, Tamer Elkafrawy, Pedro Galli Mercadante, Kenyi Hurtado Anampa, Luca Giommi, Efe Yigitbasi, Andrea Massironi, Andrey Starodumov, Jose Ruiz, Mario Pelliccioni, Caroline Collard, Alexei Safonov, WILLIAM FORD, Junghwan Goh, Spandan Mondal, Jingyan Li, German Ruben Martinez, Walter Snoeys, Evgueni Tcherniaev, Matteo Presilla, Stephen Mrenna, Jeremy Andrea, Panja Luukka, Saranya Samik Ghosh, Rogelio Reyes-Almanza, Joachim Mnich, Sandor Lokos, Fonseca de Souza Sandro, Darin Acosta, Karl Ehatäht, Aurelijus Rinkevicius, Frank Geurts, Isabel Josa Mutuberria, Junquan Tao, Paul Kyberd, Ece ASILAR, David D'Enterria, Sergey Polikarpov, Daniel Savoiu, Adish Vartak, Francesco Fienga, Jay Lawhorn, Arabella Martelli, Robert Cousins, Santeri Laurila, Jorma Tuominiemi, Andrey Popov, Jehad Mousa, Martin Grunewald, Tirso Alejandro Gomez Espinosa, Paolo Spagnolo, Nicholas Wardle, Redwan Habibullah, Robert Klanner, Frank Golf, Isidro González Caballero, Crisostomo Sciacca, Oscar Gonzalez Lopez, Tahys Janssen, Jeremi Niedziela, Robert Bainbridge, Elizabeth Starling, Andrea Rizzi, Javier Alberto Murillo Quijada, Klaus Rabbertz, Luigi (Gigi) Rolandi, Federica Legger, Andrew Ivanov, ANKITA MEHTA, Ioannis Papadopoulos, Greg Landsberg, Malte Backhaus, Aliakbar Ebrahimi, INSEOK YOON, Sara Fiorendi, ANDREA PICCINELLI, Dmitry Kirpichnikov, Arsen Khvedelidze, Jennifer Ngadiuba, Tamas Almos Vami, Ivan Heredia de la Cruz, Maciej Malawski, Vuko Brigljević, Thomas McCauley, Vittorio Raoul Tavolaro, Pablo Martinez Ruiz del Arbol, Davide Fiorina, Kaur Sandeep, Reddy Pratap Gandrajula, Luca Malgeri, Leszek Grzanka, Peter Elmer, Lea Caminada, Kenneth Osterberg, Emil Sørensen Bols, Leandar Litov, Lata Panwar, Zhicai Zhang, Anton Stepennov, Arnd Meyer, Tatyana Dimova, Christophe Ochando, Gabriel Ramirez Sanchez, Alberto Ruiz Jimeno, J B Singh, Johannes Lange, Peter Wittich, Maria Cruz Fouz Iglesias, Korbinian Schweiger, Gaetano Marco Dallavalle, Pietro Faccioli, Rafael Eduardo Sosa Ricardo, Avi Yagil, Muhammad Gul, Jaana Heikkilä, Arne Christoph Reimers, Michele Arneodo, José Flix Molina, Javier Fernandez Menendez, Alexander Tapper, Valeria D'Amante, Sandra S. Padula, George Alverson, Lev Dudko, Juan Pablo Fernández Ramos, Karl Ecklund, Martin Delcourt, Salvatore Costa, Yacine Haddad, Carlos Eugenio Perez Lara, Paolo Meridiani, Ignacio Redondo, Marco Monteno, Gautier Hamel de Monchenault, Salvatore Rappoccio, Gerrit Van Onsem, Thomas Reis, Anna Colaleo, Marco CUFFIANI, Torben Lange, Lutz Feld, Varun Sharma, Gabriella Pásztor, Nicolas Stylianou, Sung-Won Lee, Joel Goldstein, Daniel Diaz, Paolo Azzurri, Oleg Filatov, Sergio Lo Meo, Welathantri Dharmaratna, ÜMİT SÖZBİLİR, Davide Zuolo, Ram Krishna Sharma, Ian Watson, Javier Mauricio Duarte, Vilius Cepaitis, Andreas Hinzmann, Nikkie Deelen, Matthias Kasemann, Manfred Paulini, Paolo Dini, Andre Frankenthal, Kevin Lannon, Mithat Kaya, Florian Beaudette, Barbara Alvarez Gonzalez, Nuno Leonardo, Maxim Titov, Laurent Forthomme, Jose Enrique Palencia Cortezon, Rainer Wallny, Pietro Vischia, Schoefbeck Robert, Thea Aarrestad, Kevin Mota Amarilo, Gaia Grosso, Pieter David, Liuyao Zhang, Tae Jeong Kim, Marco Pieri, Sunil Manohar Dogra, Shabnam Jabeen, Guido Emilio Tonelli, Mar Capeans, Davide Di Croce, Upul Sonnadara, Ugur Kiminsu, J.F. Benitez, Luiz Mundim, Jason Lee, Jorgen D'Hondt, Maria Cepeda, Pallabi Das, Ksenia De Leo, Deborah Pinna, Morgan Lethuillier, Soureek Mitra, Bruno Lenzi, Sergio Novaes, Antonio Delgado Peris, Amina Zghiche, Pieter Everaerts, Gurpreet Singh Chahal, Hannu Siikonen, Mohammed Attia Mahmoud, André David Tinoco Mendes, Olga Evdokimov, Pierluigi Bortignon, Shubhanshu Chauhan, Carlos Perez Dengra, Simone Gennai, Freya Blekman, Furkan Dolek, Umberto Dosselli, Federica Maria Simone, Raffaele Gerosa, Benjamin Krikler, Geoffrey Hall, Eija Tuominen, Marko Dragicevic, Antonio Perez-Calero Yzquierdo, Nadezda Chernyavskaya, Mykhailo Dalchenko, Joona Juhani Havukainen, Biagio Rossi, Ibrahim Soner Zorbakir, Pavel Parygin, Sandra Consuegra Rodriguez, Roberto Covarelli, Chiara Amendola, Christophorus Grab, Mojtaba Mohammadi Najafabadi, Henning Flaecher, Dilson De Jesus Damiao, Arthur Moraes, Lucas Taylor, Graham Wilson, Rui Xiao, Minsuk Kim, Francisco Matorras, Alberto Sanchez-Hernandez, Tobias Robert Jakob Kramer, Marino Missiroli, Jan-Frederik Schulte, Fotios Ptochos, Shudhashil Bharthuar, Justin Williams, Helen Heath, Wolfgang Waltenberger, Henning Kirschenmann, Hannes Jung, Emrah Tiras, Camilo Carrillo Montoya, Yu Zhang, Alberto Zucchetta, Ralf Ulrich, Calandri Alessandro, Tahereh Sadat Niknejad, Guillelmo Gomez-Ceballos, Felipe Araujo, Kadri Ozdemir, Patrizia Azzi, Muhammad Alibordi, Vladimir Gavrilov, Johannes Haller, Kati Lassila-Perini, Abhijith Gandrakota, Konstantinos Theofilatos, Gouranga Kole, Eliza Melo da Costa, Andrea Davide Benaglia, Sebastian Wuchterl, Jesus Puerta Pelayo, Laura Martikainen, Ram Krishna Dewanjee, Christophe Delaere, Simon Regnard, Aaron Dominguez, Emanuele Usai, Matthew Herndon, Kenichi Hatakeyama, LUCA GUZZI, Alberto Belloni, Harrison Bertrand Prosper, Federico Siviero, Mariana Shopova, Mauro Donega, Abideh Jafari, Antonio Cassese, Federico De Guio, UTTIYA SARKAR, Aashaq Shah, Oliver Gutsche, Claudio Caputo, Mauro Emanuele Dinardo, Elisabetta Manca, Amedeo Staiano, Soumya Mukherjee, Thiago Rafael Fernandez Perez Tomei, Sudhir Malik, Clemens Lange, and Bożena Boimska

Published
2022
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26. The Shift to Personal Learning Environment has been FruitfulPredicting Performance in Future Tasks Based on Personal Learning Environment Management during the Corona Epidemic

Author

usama mohamed ibrahem, badr alharbi, Mahmoud Moussa, Muna Alrashidi, and Bahgat Radi

Abstract

The study aimed to study the performance expectation in future tasks based on personal learning management during the Corona epidemic. A random sample of 871 students from the University of Hail was selected. The study samples were from humanities, engineering, and medical colleges. The study was based on a cross-sectional study design. The study prepared a measure of future expectation of performance on the tasks. The scale is 28 items. Factor analysis was used to verify the validity of the scale, and the scale achieved acceptable indicators of good fit. The scale achieved acceptable stability using Cronbach's alpha coefficient for emotional factor 0.57, cognitive factor 0.94, and behavioral factor 0.90. The results revealed that there are differences in the future expectation on performance because of gender and type of college. The results revealed that there are positive correlations between future expectation of cognitive and emotional performance, as well as a positive relationship between emotional and behavioral performance. There was also a negative relationship between behavioral and cognitive performance.

Published
2022
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27. Precision measurement of the W boson decay branching fractions in proton-proton collisions at s=13 TeV

Author

Mikko Voutilainen, Stefaan Tavernier, Jordan Nash, Francisco Garcia, Raghunath Pradhan, Gabriella Pugliese, Alberto Escalante del Valle, Praveen Chandra Tiwari, Mate Csanad, Kadir Saygin, Kenneth Bloom, Pietro Govoni, Maximilian Pérez Prada, Arie Bodek, Riccardo Salvatico, Mikhail Dubinin, Andrea Cardini, Chang-Seong Moon, Ted Kolberg, Guenakh Mitselmakher, Kun Shi, Caglar Zorbilmez, Lorenzo Viliani, Ankush Reddy Kanuganti, Wesley Smith, Mikael Myllymäki, Hesham El Faham, Walaa Elmetenawee, Erhan Gülmez, Giovanni Abbiendi, Fabrizio Palla, Valentina Sola, Matthias Schröder, Cristina Riccardi, Sami Lehti, Abanti Ranadhir Sahasransu, Joseph Reichert, Jussi Viinikainen, Badder Marzocchi, Luke Kreczko, Hugues Lattaud, FLAVIA CETORELLI, Georgios Konstantinos Krintiras, Samet Lezki, Stefano Belforte, Maria Savina, Reza Goldouzian, Márton Bartók, Daniele Fasanella, Erika Garutti, Louis Moureaux, Nadia Pastrone, Danyer Pérez Adán, Muhammad Ahmad, Konstantin Androsov, Toni Sculac, Arun Kumar, Andreas Pfeiffer, Jorge Berenguer Antequera, Giuseppe Della Ricca, Eduard De La Cruz Burelo, Joern Schwandt, Christopher Tully, Luigi Calligaris, Wael HAJ AHMAD (Vael HAJAHMAD), Jennifer Ott, Francisco Javier Cuevas Maestro, Steffen Albrecht, Pablo Matorras-Cuevas, Prabhat Ranjan Pujahari, Alessandra Cappati, Alexander Belyaev, Florian Bury, James Buchanan, Roman Kogler, Andrea Giammanco, Marco Toliman Lucchini, Guenther Dissertori, Francesca Cavallari, José María Hernández Calama, Antonello Pellecchia, Efe Yazgan, Nils Faltermann, Yuri Gershtein, Sinan Sagir, Tomas Lindén, Halil Saka, Luca Cadamuro, Florencia Canelli, Simone Pigazzini, Armando Bermudez Martinez, Dmitri Konstantinov, Ksenia Shchelina, Cesar Augusto Bernardes, Bingran Wang, Qiang Li, Nicolò Trevisani, Tapio Lampén, Md Naimuddin, Barry Blumenfeld, Leonid Levchuk, Claudio Grandi, Giovanni Petrucciani, Dayong Wang, Marco Zanetti, Cristina Botta, Danilo Meuser, Martti Raidal, John Conway, Jaime Leon Holgado, Paolo Giacomelli, Jay R. Dittmann, Yalcin Guler, Agni Bethani, Marcin Konecki, Franco Ligabue, Alexander Grohsjean, Lourdes Urda, Mahmoud Moussa Abdelkhalek Gadallah, Silvano Tosi, Martina Malberti, Merve Ince Lezki, Jochen Schieck, Leonardo Cristella, Ernesto Migliore, Pritam Kalbhor, Silvia Goy Lopez, Ashish Sharma, Tommaso Diotalevi, Nikolaos Manthos, Lisa Benato, Suman Chatterjee, Émilien Chapon, Stéphane PERRIES, JUAN ALCARAZ MAESTRE, Antonio Vilela Pereira, Álvaro Navarro-Tobar, Thong Q. Nguyen, Zhenbin Wu, Maria Clemencia Mora Herrera, Zhengyun You, Agostino De Iorio, Ilaria Vai, Gilvan Alves, Sandeep Bhowmik, Cristina Fernández Bedoya, Nabin Poudyal, Markus Seidel, Andre Sznajder, Ali Eren Simsek, Tamer Elkafrawy, Pedro Galli Mercadante, Kenyi Hurtado Anampa, Luca Giommi, Efe Yigitbasi, Andrea Massironi, Andrey Starodumov, Jose Ruiz, Mario Pelliccioni, Caroline Collard, Alexei Safonov, WILLIAM FORD, Junghwan Goh, Spandan Mondal, Jingyan Li, German Ruben Martinez, Walter Snoeys, Evgueni Tcherniaev, Matteo Presilla, Stephen Mrenna, Jeremy Andrea, Panja Luukka, Saranya Samik Ghosh, Rogelio Reyes-Almanza, Joachim Mnich, Sandor Lokos, Darin Acosta, Karl Ehatäht, Aurelijus Rinkevicius, Frank Geurts, Isabel Josa Mutuberria, Junquan Tao, Paul Kyberd, Ece ASILAR, David D'Enterria, Daniel Savoiu, Adish Vartak, Francesco Fienga, Jay Lawhorn, Arabella Martelli, Robert Cousins, Santeri Laurila, Jorma Tuominiemi, Andrey Popov, Jehad Mousa, Martin Grunewald, Tirso Alejandro Gomez Espinosa, Paolo Spagnolo, Nicholas Wardle, Redwan Habibullah, Robert Klanner, Frank Golf, Isidro González Caballero, Crisostomo Sciacca, Oscar Gonzalez Lopez, Tahys Janssen, Jeremi Niedziela, Robert Bainbridge, Elizabeth Starling, Andrea Rizzi, Javier Alberto Murillo Quijada, Klaus Rabbertz, Luigi (Gigi) Rolandi, Federica Legger, Andrew Ivanov, ANKITA MEHTA, Ioannis Papadopoulos, Greg Landsberg, Malte Backhaus, Aliakbar Ebrahimi, INSEOK YOON, Sara Fiorendi, ANDREA PICCINELLI, Dmitry Kirpichnikov, Jennifer Ngadiuba, Tamas Almos Vami, Ivan Heredia de la Cruz, Maciej Malawski, Vuko Brigljević, Thomas McCauley, Vittorio Raoul Tavolaro, Pablo Martinez Ruiz del Arbol, Davide Fiorina, Kaur Sandeep, Reddy Pratap Gandrajula, Luca Malgeri, Leszek Grzanka, Peter Elmer, Lea Caminada, Kenneth Osterberg, Emil Sørensen Bols, Leandar Litov, Lata Panwar, Zhicai Zhang, Anton Stepennov, Arnd Meyer, Tatyana Dimova, Christophe Ochando, Gabriel Ramirez Sanchez, Alberto Ruiz Jimeno, J B Singh, Johannes Lange, Peter Wittich, Maria Cruz Fouz Iglesias, Korbinian Schweiger, Gaetano Marco Dallavalle, Pietro Faccioli, Rafael Eduardo Sosa Ricardo, Avi Yagil, Muhammad Gul, Jaana Heikkilä, Arne Christoph Reimers, Michele Arneodo, José Flix Molina, Javier Fernandez Menendez, Alexander Tapper, Valeria D'Amante, Sandra S. Padula, George Alverson, Lev Dudko, Juan Pablo Fernández Ramos, Karl Ecklund, Martin Delcourt, Salvatore Costa, Yacine Haddad, Paolo Meridiani, Ignacio Redondo, Marco Monteno, Gautier Hamel de Monchenault, Salvatore Rappoccio, Gerrit Van Onsem, Bora Akgun, Thomas Reis, Anna Colaleo, Marco CUFFIANI, Torben Lange, Lutz Feld, Varun Sharma, Gabriella Pásztor, Nicolas Stylianou, Sung-Won Lee, Joel Goldstein, Daniel Diaz, Paolo Azzurri, Oleg Filatov, Welathantri Dharmaratna, Benedikt Vormwald, Davide Zuolo, Ram Krishna Sharma, Ian Watson, Javier Mauricio Duarte, Vilius Cepaitis, Andreas Hinzmann, Nikkie Deelen, Matthias Kasemann, Manfred Paulini, Paolo Dini, Andre Frankenthal, Kevin Lannon, Mithat Kaya, Myriam Schönenberger, Florian Beaudette, Barbara Alvarez Gonzalez, Nuno Leonardo, Maxim Titov, Laurent Forthomme, Jose Enrique Palencia Cortezon, Rainer Wallny, Pietro Vischia, Schoefbeck Robert, Thea Aarrestad, Pieter David, Liuyao Zhang, Tae Jeong Kim, Marco Pieri, Sunil Manohar Dogra, Shabnam Jabeen, Guido Emilio Tonelli, Mar Capeans, Davide Di Croce, Ugur Kiminsu, J.F. Benitez, Luiz Mundim, Jason Lee, Jorgen D'Hondt, Maria Cepeda, Pallabi Das, Ksenia De Leo, Deborah Pinna, Morgan Lethuillier, Soureek Mitra, Bruno Lenzi, Sergio Novaes, Antonio Delgado Peris, Amina Zghiche, Pieter Everaerts, Gurpreet Singh Chahal, Hannu Siikonen, Mohammed Attia Mahmoud, André David Tinoco Mendes, Olga Evdokimov, Pierluigi Bortignon, Shubhanshu Chauhan, Simone Gennai, Ahmad Lotfy Abdelfattah Ahmad, Freya Blekman, Furkan Dolek, Federica Maria Simone, Raffaele Gerosa, Benjamin Krikler, Geoffrey Hall, Eija Tuominen, Marko Dragicevic, Antonio Perez-Calero Yzquierdo, Nadezda Chernyavskaya, Viola Sordini, Mykhailo Dalchenko, Joona Juhani Havukainen, Biagio Rossi, Ibrahim Soner Zorbakir, Pavel Parygin, Sandra Consuegra Rodriguez, Roberto Covarelli, Chiara Amendola, Christophorus Grab, Mojtaba Mohammadi Najafabadi, Henning Flaecher, Dilson De Jesus Damiao, Arthur Moraes, Lucas Taylor, Graham Wilson, Rui Xiao, Minsuk Kim, Francisco Matorras, Alberto Sanchez-Hernandez, Tobias Robert Jakob Kramer, Marino Missiroli, Jan-Frederik Schulte, Fotios Ptochos, Shudhashil Bharthuar, Justin Williams, Helen Heath, Wolfgang Waltenberger, Henning Kirschenmann, Hannes Jung, Emrah Tiras, Camilo Carrillo Montoya, Alberto Zucchetta, Ralf Ulrich, Calandri Alessandro, Tahereh Sadat Niknejad, Guillelmo Gomez-Ceballos, Felipe Araujo, Kadri Ozdemir, Patrizia Azzi, Muhammad Alibordi, Vladimir Gavrilov, Johannes Haller, Kati Lassila-Perini, Abhijith Gandrakota, Konstantinos Theofilatos, Gouranga Kole, Eliza Melo da Costa, Andrea Davide Benaglia, Sebastian Wuchterl, Jesus Puerta Pelayo, Laura Martikainen, Ram Krishna Dewanjee, Christophe Delaere, Simon Regnard, Aaron Dominguez, Emanuele Usai, Matthew Herndon, Kenichi Hatakeyama, LUCA GUZZI, Alberto Belloni, Harrison Bertrand Prosper, Federico Siviero, Mariana Shopova, Mauro Donega, Abideh Jafari, Antonio Cassese, Federico De Guio, UTTIYA SARKAR, Aashaq Shah, Oliver Gutsche, Claudio Caputo, Mauro Emanuele Dinardo, Elisabetta Manca, Amedeo Staiano, Soumya Mukherjee, Thiago Rafael Fernandez Perez Tomei, Sudhir Malik, Clemens Lange, and Bożena Boimska

Published
2022
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41. Information hiding using artificial DNA sequences based on Gaussian kernel function

Author

Eman I. Abd El-Latif and Mahmoud Moussa

Subjects
Theoretical computer science, Computer science, business.industry, Data security, Cryptography, 010103 numerical & computational mathematics, 02 engineering and technology, Function (mathematics), 01 natural sciences, DNA sequencing, symbols.namesake, Dna cryptography, Information hiding, 0202 electrical engineering, electronic engineering, information engineering, Gaussian function, symbols, 020201 artificial intelligence & image processing, Hardware_ARITHMETICANDLOGICSTRUCTURES, 0101 mathematics, business
Abstract

Cryptography is one of the major concerned areas of computer networks and data security. An efficient direction of providing data security can be termed as DNA based on cryptography. In this paper,...

Published
2019
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42. COMBINES-CID: An Efficient Method for De Novo Engineering of Highly Specific Chemically Induced Protein Dimerization Systems

Author

Huayi Jiang, Frank DiMaio, Shoukai Kang, Molly Jahn, Kristian Davidsen, Liangcai Gu, Mahmoud Moussa, Luis Gomez-Castillo, Zengpeng Li, Yu Liang, and Xiaonan Fu

Subjects
Ligand, Chemistry, Small molecule ligand, General Chemistry, Protein engineering, 010402 general chemistry, 01 natural sciences, Biochemistry, Small molecule, Combinatorial chemistry, Catalysis, 0104 chemical sciences, Colloid and Surface Chemistry, Chemically induced dimerization, Selectivity, Protein Dimerization, Biosensor
Abstract

Chemically induced dimerization (CID) systems, in which two proteins dimerize only in the presence of a small molecule ligand, offer versatile tools for small molecule sensing and actuation. However, only a handful of CID systems exist and creating one with the desired sensitivity and specificity for any given ligand is an unsolved problem. Here, we developed a combinatorial binders-enabled selection of CID (COMBINES-CID) method broadly applicable to different ligands. We demonstrated a proof-of-principle by generating nanobody-based heterodimerization systems induced by cannabidiol with high ligand selectivity. We applied the CID system to a sensitive sandwich enzyme-linked immunosorbent assay-like assay of cannabidiol in body fluids with a detection limit of ∼0.25 ng/mL. COMBINES-CID provides an efficient, cost-effective solution for expanding the biosensor toolkit for small molecule detection.

Published
2019
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43. Synthesis of three phase graphene/titania/polydimethylsiloxane nanocomposite films and revealing their dielectric and impedance properties

Author

Saira Ishaq, Shahid Atiq, Farah Kanwal, Mahmoud Moussa, Dusan Losic, Ishaq, Saira, Kanwal, Farah, Atiq, Shahid, Moussa, Mahmoud, and Losic, Dusan

Subjects
Permittivity, dielectric permittivity, Materials science, 02 engineering and technology, Dielectric, 01 natural sciences, law.invention, chemistry.chemical_compound, law, 0103 physical sciences, Materials Chemistry, titania, polydimethylsiloxane, Ceramic, Composite material, Electrical impedance, 010302 applied physics, Nanocomposite, Polydimethylsiloxane, Graphene, Process Chemistry and Technology, graphene, 021001 nanoscience & nanotechnology, AC conductivity, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry, visual_art, Ceramics and Composites, visual_art.visual_art_medium, Dissipation factor, 0210 nano-technology
Abstract

Compounds and composites with high dielectric performance are in high demand in electronic industry due to their ability to store more charge and lower energy dissipation. In this paper we present synthesis of flexible three phase nanocomposite films of graphene/titania/polydimethylsiloxane with reasonably high real part of permittivity and very low imaginary part of permittivity. Dielectric permittivity of polydimethylsiloxane was raised by addition of graphene and rutile titania used as conducting and ceramic additives, respectively added in various weight ratios. Dielectric studies of synthesized three phase graphene/titania/polydimethylsiloxane nanocomposite films with weight/weight of 2:15:20 exhibits dielectric permittivity of 34.8 even at very high frequency of 2 MHz. While loss tangent of the same three phase graphene/titania/polydimethylsiloxane nanocomposite film is as low as 0.01 and its AC conductivity is 4.3 × 10⁻⁵ Sm⁻¹. Complex impedance and complex electric modulus of three phase graphene/titania/polydimethylsiloxane nanocomposite films also confirm its capacitive behaviour. Based on these properties and results we propose that these type of three phase graphene/titania/polydimethylsiloxane nanocomposite films can be used as useful dielectric materials in energy storage devices. Refereed/Peer-reviewed

Published
2019
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45. An upper bound of radio k-coloring problem and its integer linear programming model

Author

Mahmoud Moussa and E. M. Badr

Subjects
Integer linear programming model, Computer Networks and Communications, Computer science, 020206 networking & telecommunications, 020302 automobile design & engineering, 02 engineering and technology, Solver, Polynomial algorithm, Upper and lower bounds, Graph, Vertex (geometry), Combinatorics, 0203 mechanical engineering, 0202 electrical engineering, electronic engineering, information engineering, Path graph, Electrical and Electronic Engineering, Coloring problem, Connectivity, Information Systems
Abstract

For a positive integer k, a radio k-coloring of a simple connected graph G = (V(G), E(G)) is a mapping $$f:V(G) \to \{ 0,1,2, \ldots \}$$ such that $$|f(u) - \,f(v)| \ge k + 1 - d(u, \, v)$$ for each pair of distinct vertices u and v of G, where d(u, v) is the distance between u and v in G. The span of a radio k-coloring f, rck(f), is the maximum integer assigned by it to some vertex of G. The radio k-chromatic number, rck(G) of G is min{rck(f)}, where the minimum is taken over all radio k-colorings f of G. If k is the diameter of G, then rck(G) is known as the radio number of G. In this paper, we propose an improved upper bound of radio k-chromatic number for a given graph against the other which is due to Saha and Panigrahi (in: Arumugan, Smyth (eds) Combinatorial algorithms (IWOCA 2012). Lecure notes in computer science, vol 7643, Springer, Berlin, 2012). The computational study shows that the proposed algorithm overcomes the previous algorithm. We introduce a polynomial algorithm [differs from the other that is due to Liu and Zhu (SIAM J Discrete Math 19(3):610–621, 2005)] which determines the radio number of the path graph Pn. Finally, we propose a new integer linear programming model for the radio k-coloring problem. The computational study between the proposed algorithm and LINGO solver shows that the proposed algorithm overcomes LINGO solver.

Published
2019
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46. Cobalt Cyclotetraphosphate (Co2P4O12): A New High-Performance Electrode Material for Supercapacitors

Author

Deepak R. Patil, B. Koteswararao, Arvind Yogi, Deepak P. Dubal, Krishna Begari, and Mahmoud Moussa

Subjects
Supercapacitor, Materials science, Analytical chemistry, Energy Engineering and Power Technology, chemistry.chemical_element, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Electrochemistry, 01 natural sciences, 7. Clean energy, Capacitance, Energy storage, 0104 chemical sciences, chemistry, Electrode, Materials Chemistry, Chemical Engineering (miscellaneous), Specific energy, Electrical and Electronic Engineering, 0210 nano-technology, Cobalt, Faraday efficiency
Abstract

Recently, transition metal phosphates (TMPs) are demonstrated as promising candidates for supercapacitors due to their good conductivity and long-term stability. Herein, we have inrtoduced cobalt cyclotetraphosphate (Co2P4O12) as novel supercapacitive electrode material, which deliver a capacitance of 437 F/g with good stability over 3000 cycles (around 90%). To display the practical relevance, we have fabricated asymmetric device using activated carbon and Co2P4O12 as negative and positive electrodes, respecitvely, which can be operated up to 1.4 V. The introduction of redox-active moieties (such as potassium iodide (KI)) in parent KOH solution enhances the capacitance from 120 F/g to 156 F/g for Co2P4O12//AC cell with extended voltage window (1.8 V). Owing to the additional voltage and advancement in the capacitance, the cell delivers battery-level energy of 70 Wh/kg at power density of 2.3 kW/kg. It should be emphasized that even at high power (7.6 kW/kg), the cell maintained very good specific energy of 48 Wh/kg, suggesting excellent rate performance. The asymmetric device further showed long cycling stability with negligible loss and excellent Coulombic efficiency over 5000 cycles. Thus, metal cyclotetraphosphate can be employed as a promising electrode material in energy storage systems.

Published
2019
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47. Transcerebellar diameter versus biparietal diameter for the measurement of gestational age in third trimester

Author

Mohamed Adel, Ali, Eman, AbdElSalam NasrElDin, and Mahmoud, Moussa

Abstract

To compare the accuracy of biparietal diameter and transcerebellar diameter in measuring the gestational age during the third trimester of pregnancy.In this prospective observational study, 275 pregnant women with singleton pregnancy between 32 and 37 weeks gestational age were recruited from the outpatient clinics of both Helwan University Hospital and Ain Shams University Maternity Hospital, Cairo, Egypt, during the period from February 2021 to August 2021. Transcerebellar and biparietal diameters of the fetus were measured by a radiologist blinded to the women's gestational age, and compared to the gestational age acquired from a reliable date of first day of last menstrual period.The gestational age calculated by first day of last menstrual period ranged from 32 to 37 weeks (34.35 ± 1.4), while estimated by transcerebellar and biparietal diameters ranged from 31 to 37 weeks (34.31 ± 1.39) and 31 to 39 weeks (34.32 ± 1.44), respectively. There was a strong positive correlation between gestational age and transcerebellar diameter (Transcerebellar diameter is a reliable single sonographic fetal biometric parameter for the assessment of gestational age in third trimester of pregnancy.

Published
2021

48. Quantitative Evaluation of Palatal Lengthening After Cleft Palate Repair When a Buccal Flap Is Routinely Combined With Furlow's Z-Plasty

Author

Tarek Mahmoud Aly, Mohammed Ahmed Hussein, Mahmoud Mohamed Akram khodir, Mamdouh Ahmed Aboulhassan, and Hassan Mahmoud Moussa

Subjects
Sling (implant), Primary palate, medicine.medical_treatment, Oral Surgical Procedures, Facial Muscles, Surgical Flaps, Palatal Muscles, medicine, Humans, Orthodontics, business.industry, Palate, Mouth Mucosa, Soft tissue, Infant, Buccal administration, Plastic Surgery Procedures, Buccinator, Cleft Palate, medicine.anatomical_structure, Z-plasty, Surgery, Hard palate, Palatal Muscle, Palate, Soft, business
Abstract

INTRODUCTION The use of a buccinator myomucosal flap in combination with Furlow's Z-plasty during primary and secondary palatal repairs has been proposed by many authors to overcome some of the limitations of Furlow's technique. However, there have been no studies that quantitatively measured the effective palatal lengthening when the buccal flap is added. PATIENTS AND METHODS The buccal flap is routinely used during primary palate repair in order to fill the gap between the hard palate and reoriented palatal muscle sling. The soft palatal length was measured in the midline from the posterior edge of the hard palate to the base of the uvula. All patients were measured before starting the surgery and just after palatal closure in the standard position for cleft palate repair. RESULTS Seventy-three patients with cleft palate who were candidates for primary repair were included. The mean age at the time of operation was 11.4 ± 3.5 months. The mean preoperative palatal length was 21.36 ± 3.529 mm, whereas the mean postoperative palatal length was 29.64 ± 4.171) mm. The mean palatal length change was 8.29 ± 2.514 mm (P < 0.000). CONCLUSIONS The Combined use of a buccinator myomucosal flap with modified Furlow's Z-plasty in primary cleft palate repair has proven effective for palatal lengthening and achieved tensionless closure without the need for relaxing incision. It also provided a pliable soft tissue attachment of the palatal muscles to the hard palate allowing for better muscle function and mobility.

Published
2021

49. Prevalence and Assessment of Potentially Inappropriate Medications among Lebanese Elderly inpatients

Author

Nisreen Mourad, Mohamad Rahal, Alissar Chirazi, Maya Hassan, Mohamed Hendaus, Samar Younes, and Mahmoud Moussa

Subjects
medicine.medical_specialty, business.industry, hemic and lymphatic diseases, Potentially Inappropriate Medications, Medicine, business, Intensive care medicine
Abstract

Background: Potentially inappropriate medications (PIMs) prescribing in older increases the risk of hospitalization, drug-related problems, and other adverse health outcomes by two to three folds (Lu WH, 2015) (WHO, 2018). Hence several regulations have been implemented in geriatric clinical practice to improve drug appropriateness. This study aimed to assess the prevalence of PIMs identified by the Beers 2019 criteria among Lebanese elderly inpatients, and to identify the factors that may influence such inappropriateness.Methods: This observational study was conducted among elderly patients of 3 hospitals in Lebanon. Data were collected from patients using a questionnaire based on the 2019 Beers criteria. Descriptive statistics and multivariable logistic regression were used to describe and identify the predictors of PIMs use. Statistical analysis was carried out using the SPSS software version 22.0.Results: A total of 110 in-patients aging 65 years and older were analyzed. 80% of patients were taking drugs that are considered PIMs to be avoided; The most commonly prescribed PIM was proton pump inhibitors (PPIs) (60%). PIMs use was significantly associated with polypharmacy and other comorbid conditions (p-value

Published
2021
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50. Selective allocation of patients with vaginal apical prolapse to either mesh augmented open abdominal repair or vaginal sacrospinous colpopexy improve functional and anatomical outcomes

Author

Mahmoud F. Hassan, Osama El-Tohamy, Amr Helmy Yehia, Salha A. Alghanimi, Hessa Al-Enezi, and Mahmoud Moussa

Subjects
General Medicine
Abstract

Background: To evaluate the functional and anatomical outcomes after allocation of patients with apical vaginal prolapse to either mesh augmented abdominal repair or vaginal sacrospinous-colpopexy based on proposed selection criteria.Methods: A non-randomized trial was conducted at Ain-Shams university maternity hospital on patients with apical vaginal prolapse stage ≥2 based on pelvic organ prolapse quantification system. Certain criteria were proposed for patient selection to either mesh augmented abdominal repair or vaginal sacrospinous-colpopexy. Seventy-eight patients were assigned for sacrospinous-colpopexy and 47-patients for abdominal repair. Primary outcomes were the functional outcome using urogenital distress inventory questionnaire and patient global impression of improvement (PGI-I). Both were measured at 1-year’s follow-up. Secondary outcomes involved the anatomical success (defined as no apical prolapse ≥POP-Q stage 2), perioperative data and long-term complications.Results: There was improvement in all UDI domains for sacrospinous-colpopexy and abdominal repair groups with genital prolapse domain of median (interquartile range) 0 (0-10), 0 (0-0) respectively. Eighty-nine percent of abdominal repair group and 85% of sacrospinous-colpopexy group reported scale of 1 or 2 on PGI-I scale at 1-year follow-up. PGI-I score and improvements in UDI domains were maintained till 5-year follow-up. The anatomic success rate at 1-year follow-up was 97.9% in abdominal repair group and 78.2% in the sacrospinous-colpopexy group. No long-term mesh complications were detected in mesh augmented abdominal repair over the whole follow-up periods.Conclusion: The resulting meritorious functional and anatomical outcomes favor adoption of our proposed selection criteria in the initiation of guidelines and recommendations for managing vaginal apical prolapse.

Published
2022
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