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Background We aim to compare the diameters of ascending aorta in COVID-19 patients and COVID–19-free individuals referred to our pandemic hospital. Methods The medical records and thorax tomographies of patients admitted to the “pandemic central” state hospital with symptoms of COVID-19 were observed between April 2020 and May 2020 in this case-control study. The first group consisted of patients diagnosed with COVID-19, and the second group consisted of patients without the disease. The diameter of the ascending aorta is measured via tomography and compared to each other. The most causative risk factors for aortic enlargements underwent a multivariate regression analysis. Results Charts of 156 patients (104 COVID-19 positives, 52 COVID-19 negatives) were reviewed. There was a statistical difference ( p: .01) between the mean aortic diameter of COVID-19 patients (39 mm) and COVID-free patients (32.5 mm) even though comorbid factors and patient characteristics were similar in the two groups at the time of hospital admission. The regression analysis result demonstrates that COVID-19 (leading factor), age, and coronary artery disease were the most significant factors associated with increasing aortic dimensions. ( p: .001, B: 5.3/, p: .02, B: 3.36/, p: .002, B: 0.13/, R square: 40.2%). Conclusion This study shows that the mean aortic diameter of COVID-19 patients is larger than non–COVID-19 patients with similar comorbidities referred to a pandemic hospital. COVID-19, age, and coronary artery disease are the most influential factors that affect the aortic diameter, and the COVID-19 was the leading factor.

The present study aimed to compare the clinical outcomes of heart transplant patients whose donor hearts were preserved with the SherpaPak controlled cold organ system versus the conventional ice storage technique.All patients undergoing heart transplantation at our center between January 2019 and April 2021 were divided into two groups according to the technique used during donor heart preservation and transport. The first group consisted of 34 SherpaPak controlled temperature preservation patients, and the second group consisted of 47 patients where the conventional three bags and ice technique was utilized during organ transportation. The two groups were compared based on demographics, operative details, and postoperative outcomes.There were no significant differences between the groups regarding Vasoactive Inotropic Score (VIS), Primary Graft Dysfunction (PGD), and the need for a transient pacer. However, the VIS, PGD, and pacing trends were lower in the SherpaPak patients even though the total ischemic and cardiopulmonary bypass times were significantly longer. Furthermore, SherpaPak patients exhibited a shorter stay in the ICU with no severe PGD and mortality.The SherpaPak donor heart preservation provides safe outcomes in heart transplant patients. Further research is needed to utilize this method for longer durations of ischemic time and expand travel distances for organ transportation.

ObjectivesThe endovenous thermal ablation of the greater saphenous vein under spinal anesthesia is still a popular technique. Although this procedure is considered to be fast and simple, side effects such as headaches, vomiting, and urinary retention could occur. These side effects make the recovery period difficult for the patient. The patient’s age, gender, and procedural risk factors such as needle sizes and types are important parameters that affect the occurrence and rate of undesirable outcomes. This retrospective study aims to evaluate the endovenous thermal ablation method for the management of incompetent great saphenous veins under spinal anesthesia.MethodsA total of 128 patients with incompetent varicose veins who were treated with an endovenous thermal ablation method under spinal anesthesia were retrospectively investigated between January 2016 and January 2019. The pre-, intra-, post-procedural, and follow-up data of the patients were collected and retrospectively compared.ResultsA total of 128 patients (69 males, 59 females; mean age 45.8 ± 11.8 years; range 21–71 years) were included in the study. The average preprocedural great saphenous vein diameters were 7.41 ± 18.8 mm (range: 5.5–13.0). The average ablated vein length was 25.3 ± 3.4 (range: 15–35) cm. The average tumescent anesthesia use was 300.9 ± 52.6 (range: 150–500) mL. The average procedure time was 18.2 ± 1.8 (range: 11–25) min. The venous clinical severity scores and the chronic venous insufficiency quality of life questionnaire scores declined significantly ( p for venous clinical severity scores: 0.001, p for chronic venous insufficiency quality of life questionnaire scores: 0.001). There was no postoperative paresis or paresthesia. There was one case of deep venous thrombosis and three cases of bruising. The total of three months’ occlusion rates was 96.9% (124/128). The overall post-dural puncture headache ratio was 18%. Women significantly suffered from more headaches than men (27% vs. 10%, p = 0.013). The extreme age intervals (pertaining to ages between 18 and 30 or 50+) were almost significantly less affected by headaches in comparison to the group with the age interval between 31 and 50 (11.3%, 24.2%, p: 0.056). A percentage of 12.5 patients suffered from vomiting. It was recorded that female patients suffered from vomiting more so than the males (20.3%, 5.8%, p: 0.013). Pertaining to vomiting, there was no significant difference between the two age interval groups ( p: 0.14). Urinary retention was observed in 6.3% of the patients. The female gender had a higher ratio of urinary retention, but the difference was insignificant. (8.5%, 4.3%, p: 0.46). There was no significant difference between the age interval groups in terms of urinary retention.ConclusionsThe endovenous thermal ablation of the greater saphenous vein under spinal anesthesia is a fast and effective treatment option for the management of incompetent saphenous veins. However, side effects such as headaches, vomiting, and urinary retention that are affected by gender types, age-intervals, and procedural characteristics should be kept in mind.

We aimed to investigate the short-term outcomes of heart transplant patients who underwent SherpaPak™ donor organ preservation.We prospectively collected the data of patients who underwent heart transplantation using SherpaPak™ system for donor organ transportation from February 2020 to March 2021. Donor and recipient demographic data, preoperative and postoperative echocardiographic and hemodynamic parameters, total ischemic time and SherpaPak temperatures, vasoactive inotropic scores (VIS), primary graft dysfunction (PGD) status, intensive care unit stay, complications, and mortality during follow-up were assessed.A total of 39 consecutive heart transplant patients with SherpaPak system were included in the study. The mean donor age was 32.2 ± 6.7 (range: 16-46). The mean recipient age was 57.5 ± 12 (range: 19-73). The mean preoperative ejection fraction (EF) was 23.7 ± 15.4 (range: 5-75). All recipients underwent a standard bicaval technique for orthotopic heart implantation. The mean total ischemic time was 230.1 ± 41 (range: 149-342) min. The mean Sherpa temperature was 5.6 ± 0.8°C (range: 3.7-7.5). The mean VIS was 10.2 ± 6.5 (range: 2-32). The number of mild PGD was 5 (14.7%), and moderate PGD was 4 (11.8%). There was no severe PGD. The postoperative EF was 64.3 ± 5.5 (range: 50-78). Mean intubation time was 47.4 ± 64 (range: 8-312, median: 22) h. The mean time of intensive care unit stay was 6.3 ± 5 (range: 2-31, median: 5) days. Two patients required chest revision (5.8%), two patients had lung infection (5.8%). Two patients had a stroke (5.8%). There was no mortality.Using the SherpaPak system during heart transplantation is safe and not associated with significant recipient morbidity. None of the recipients experienced significant PGD and mortality.

Background: Coronavirus disease 2019 (COVID-19) is commonly complicated with coagulopathy presented with venous thromboembolism and arterial thromboses. The aim of this study was to evaluate the effect of routine thromboprophylaxis with low molecular weight heparin (LMWH) on clinical outcomes including mortality and need for intensive care unit (ICU) admission in hospitalized COVID-19 patients. Methods: All confirmed patients with COVID-19 hospitalized to COVID-19 dedicated wards, from March 15 to May 15, 2020, were included in this retrospective cohort study. Two groups of patients were established, according to the non-routine and routine application of LMWH with therapeutic, weight-based, anticoagulation dosing. Clinical, laboratory and treatment data were collected, analyzed and compared between the two groups. A logistic regression model was developed to assess the factors related to in-hospital adverse outcomes. Results: A total of 1511 patients (797 men, median age 59.0 years) were retrospectively analyzed (Group non-routine LMWH (n=828); group routine LMWH (n=683)). Multivariate logistic regression analysis showed routine use of LMWH, favipiravir administration, extreme values of WBC count, NLR, and troponin I as factors independently associated with in-hospital adverse outcomes (OR=0.25, 95% CI: 0.83-0.91; p

Introduction This study aims to evaluate the long-term results regarding the effectiveness and reliability of endovenous laser ablation (EVLA), endovenous n-butyl cyanoacrylate (NBCA) application and radiofrequency ablation (RFA) methods in the management of Chronic venous insufficiency (CVI). Methods Charts of patients treated with EVLA, NBCA and RFA methods for CVI between January 1st, 2014 and January 1st, 2017, were reviewed. Records were made of personal information including sex, age, body mass index (BMI), American Society of Anesthesiologists score (ASA) and admission symptoms. Great saphenous vein (GSV) diameter, score of CEAP (Clinical, Etiology, Anatomy and Pathophysiology) classification, and Venous Clinical Severity Score (VCSS) were also noted. All patients were followed up with physical examination and CDUS at the first week, and 6th and 12th months after the procedures. After 12th month, follow-ups were annual. Results Enrolled in the study were a total of 232 patients who underwent lower limb CVI procedures (77 patients with EVLA, 73 patients with NBCA and 82 patients with RFA). The mean follow-up time was 67.5±4.7 months. Time of procedure was significantly shorter in patients treated with NBCA (13.5 minutes) in comparison of patients treated with EVLA (31.7 minutes) and RFA (27.9 minutes) (p= 0.001). Pain score was highest in EVLA group (p= 0.001). Significantly higher complication rates and longer time to return daily activity was recorded in those undergoing EVLA procedure (p= 0.001). Post hoc analysis revealed comparable occlusion success among groups on post-operative first day, and at 6th month, first year and second year. However, significantly better success of occlusion rates were found for RFA in comparison of EVLA in third and fifth-years follow-ups (p= 0.024 and p= 0.011). The success of NBCA and RFA was similar in third and fifth-years follow-ups (p= 0.123 vs p= 0.330) Conclusion Outcomes showed similar levels of early postoperative occlusion success among all three CVI treatment techniques, but RFA has a significantly higher success rate over EVLA in the third and fifth-year follow-ups. Additionally, NBCA and RFA procedures achieved comparable long-term success. EVLA was associated with significantly higher complication rates and pain scores, and longer time to return daily activities, while NBCA procedure had a significantly shorter operation time than the other procedures.

Background Local or spinal anesthesia methods can be used during radiofrequency ablation (RFA) of the great saphenous vein. There is a gap in the literature regarding comparing and contrasting the side effects of the mentioned two methods. This study aims to retrospectively compare the spinal anesthesia method with the local tumescent anesthesia method during RFA of the great saphenous vein that also includes mini-phlebectomy. Methods We retrospectively analyzed patients who underwent RFA and mini-phlebectomy divided in two groups according to the anesthesia applied method. Group 1 contained patients who underwent the RFA operation under spinal anesthesia combined with tumescent anesthesia, and group 2 patients consisted of patients who underwent the same process under local tumescent anesthesia. Pain scores, the time length of preparation interval of anesthesia and the operation time, anesthesia-related side effects such as headache, nausea-vomiting, urinary retention, quality of life scores, postoperative occlusion rates, and complications related to the intervention such as phlebitis, deep vein thrombosis (DVT) were analyzed and compared via Mann Whitney U, Wilcoxon and Chi-Square tests. Results Between June 2015 and June 2019 a great saphenous vein RFA ablation was performed in 175 patients. A total of 103 limbs were performed under spinal anesthesia combined with tumescent anesthesia and a total of 72 limbs were performed under local tumescent anesthesia. Mini phlebectomy was applied to all patients. Pain scores of the spinal anesthesia group were lower than the other group, and there was a significant difference. There was no significant difference between the operation lengths of both groups, but the preparation phase of anesthesia was shorter in local tumescent anesthesia patients, and the difference was significant. Anesthesia related side effects such as headache, nausea-vomiting, and urinary retention showed a significant difference between the two groups, and they were lower in the local tumescent anesthesia group. Preoperative quality of life scores of both groups decreased postoperatively. The postoperative occlusion rate of group 1 was 96.1%, and group 2 was 100 % at three months, but the difference was not significant. We encountered 3 cases of phlebitis, 2 cases of DVT and 2 cases of bruising in group 1, and 1 case of bruising in group 2. There was no postoperative paresis or paresthesia in either groups. Conclusions This monocenter and retrospective report of 175 GSV RFA using tumescent local anesthesia or spinal anesthesia combined with local tumescent anesthesia demonstrares that both methods of anesthesia are effective. Although the pain scores are better with spinal anesthesia, the local tumescent anesthesia method is more efficient, requiring a shorter time, and is associated with fewer complications such as headache, nausea-vomiting, or urinary retention and deep venous thrombosis.

Objectives F-care (endovenous radiofrequency, F Care Systems, Antwerp, Belgium) is a relatively new radiofrequency ablation technique for the treatment of venous insufficiency. There is a lack of published data about F-care in literature. This study aimed to prospectively compare the F-care method with conventional endovenous radiofrequency ablation Closurefast method for the management of incompetent great saphenous veins. Methods Between June 2015 and December 2018, 114 patients with incompetent varicose veins were treated either with the F-care or Closurefast. The pre-, intra-, postprocedural, and follow-up data of the patients were collected and prospectively compared. Results The average ablated vein length was 23.1 ± 4 cm in the F-care group and 26.6 ± 4 cm in the Closurefast group ( P = 0.01). The average procedure time was 17.4 ± 4 min (range: 10–30 min) in the F-care group, and 17.1 ± 3 min (range: 11–27 min) in the Closurefast group ( P = 0.77). The one-month total occlusion rates in the F-care and Closurefast groups were 96.2% and 98.1%, respectively ( P = 0.5). The one-year full occlusion rates in the F-care and Closurefast groups were 71.7% and 90.6%, respectively ( P = 0.013). In both the F-care and Closurefast groups, the venous clinical severity scores declined significantly with no difference between groups. There was no significant difference between adverse events following F-care treatment compared with Closurefast treatment ( P ≤ 0.05). Conclusions The F-care system was as safe and fast, but the one-year closure rate was significantly lower when compared to the other method. There was no significant difference between the adverse effects of both approaches. Further large-scale, multi-center prospective studies with long-term outcomes are required to identify the effectiveness of F-care treatment modality for patients with saphenous vein insufficiency.

The endovenous application of n-butyl cyanoacrylate (NBCA) is a new nontumescent ablation technique for the treatment of venous insufficiency. The aim of this study was to retrospectively compare an NBCA-based ablation method with endovenous laser ablation (EVLA) for the management of incompetent great saphenous veins.Between May 2013 and August 2014, there were 339 patients with incompetent varicose veins who were treated with either the endovenous application of NBCA (VariClose Vein Sealing System [VVSS]; Biolas, Ankara, Turkey) or EVLA. The preprocedural, intraprocedural, postprocedural, and follow-up data of the patients were collected and retrospectively compared.The mean age was 45.09 ± 12 years in the VVSS group and 47.08 ± 11 years in the EVLA group (P = .113). The average ablated vein length was 31.97 ± 6.83 cm in the VVSS group and 31.65 ± 6.25 cm in the EVLA group (P = .97). The average tumescent anesthesia use was 300 mL (range, 60-600 mL) in the EVLA group. The average procedure time was 7 minutes (range, 4-11 minutes) in the VVSS group and 18 minutes (range, 14-25 minutes) in the EVLA group (P .01). On the basis of ultrasound examinations performed at the end of the procedure, all procedures in both groups were successful, and the target vein segments were fully occluded. The 12-month total occlusion rates in the VVSS and EVLA groups were 98.6% and 97.3%, respectively (P = .65). In both the VVSS and EVLA groups, the Venous Clinical Severity Score declined significantly with no difference between groups. There were fewer adverse events after VVSS treatment compared with EVLA treatment (pigmentation, P ≤ .002; phlebitis, P ≤ .015). There was no need for tumescent anesthesia in the VVSS group.The NBCA-based vein sealing system is a fast and effective treatment option for the management of incompetent saphenous veins that does not involve tumescent anesthesia, compression stockings, paresthesia, burn marks, or pigmentation. Further large-scale studies with long-term outcomes are required to identify the optimal treatment modalities for patients with saphenous vein insufficiency.

Thenumber of coronary angiographies performed each year is increasing worldwide.This may lead to a rise in the number of complications that will need surgicalintervention. There is a risk of entrapment of the guidewire that is used incoronary angiography inside the vessel wall. This complication is rarely seen,but may occur depending on calcifications or technical difficulties.Overstretching of the stuck wire might result in wire fracture, and this maycause embolic or thrombotic events. Treatment is challenging and can be donevia percutaneous or surgical methods. Herein, we present the case of a malepatient with an entrapment of the coronary artery guidewire inside the septalbranch of the left anterior descending artery., Yıllık yapılan koroner anjiyografi sayısı giderek artmaktadır. Buna bağlı olarak cerrahi müdahale gerektirecek komplikasyon sayılarında artış beklemekteyiz. Koroner anjiyografi esnasında kullanılan kılavuz telin damar lümeni içerisinde sıkışma ihtimali mevcuttur. Bu komplikasyon nadir olarak görülse de kalsifikasyonlara ve teknik zorluklara bağlı olarak gelişebilir. Sıkışan tel üzerinde fazla baskı oluşturmak telin kırılmasına neden olabilir. Bu embolik ya da trombotik hadiselerin gelişmesine neden olabilir. Tedavisi zorlu olan bu durum cerrahi ya da perkütan metodlar ile düzeltilebilir. Burada sol ön inen arterin septal dalında koroner arter kılavuz telinin sıkışma komplikasyonu mevcut erkek olgu takdim edilmiştir.

External jugular vein aneurysms are extremely rare pathologies compared to arterial ones. The patients often present with a painless mass in the neck that becomes visible while coughing and straining. Palpation of a soft and compressible swelling over the external jugular vein is a diagnostic hallmark. Doppler ultrasound examination is considered as the golden standard for the radiological diagnosis that allows a precise determination and confirmation of an aneurysm. Surgical excision is performed mostly for cosmetic concerns and symptomatic aneurysms. In this article, we present the clinical aspects, radiological and microscopic findings, diagnosis and surgical treatment of an external jugular vein aneurysm in a young female patient to emphasize the typical clinical presentation of this rare entity.

Blood transfusion is sometimes a necessary procedure during or following coronary artery bypass graft (CABG) surgery. However, transfusion-related acute lung injury (TRALI)/possible TRALI is a rare and fatal complication and characterized by acute hypoxemia and non-cardiogenic pulmonary edema that occurs within 6 hours following a transfusion. Anti-leukocyte antibodies or, possibly, other bioactive substances cause inflammation and capillary endothelial destruction in susceptible recipients’ lungs. Prompt diagnosis and mechanical ventilatory support are important. A successful treatment of two male patients following CABG surgery, compatible with TRALI/possible TRALI, is presented here.

Upper-extremity arterial injury is a common and serious condition that may lead to amputation if improperly treated. Ligation of the ulnar or radial artery is frequently performed by vascular surgeons as a method of treatment, which should be avoided, particularly if the radial and ulnar arteries were both injured. A different approach to reconstruction is described in the present report.

Background To report a case of a 48-year-old man with Buerger’s disease who presented with bilateral normal-tension glaucoma (NTG). Case presentation A 48-year-old man who had been diagnosed with Buerger’s disease 12 years ago, and received bilateral below-the-knee amputations for ischemic ulcers of the lower limbs, presented at our clinic due to a sudden loss of visual acuity in the left eye. A fundus exam revealed a cup-to-disc ratio of 0.5 for the right eye and 0.8 for the left eye, arteriolar constriction in both eyes, retinal edema in the inferopapillary area, and splinter hemorrhages and soft exudate in the left eye. We diagnosed the patient as having acute nasal branch retinal artery occlusion in the left eye and bilateral NTG, as a result of the ophthalmologic examination and the other findings. Conclusion Although the pathomechanism of NTG is still unknown, previous studies have suggested that patients with NTG show a higher prevalence of vasospastic disorders. We present the second report of NTG associated with Buerger’s disease to be described in the literature.

The patient admitted with the signs and symptoms of deep venous thrombosis (DVT) was diagnosed and hospitalized for inferior vena cava (IVC) filter implantation preceding a pharmaco-mechanical thrombolysis. Despite the lack of a preoperative history and a radiological finding resembling an IVC filter, intraoperative fluoroscopy revealed a previously implanted permanent device. The present case is showing that some IVC filters may be hard to be visualized preoperatively in the roentgenogram.

Lower extremity lymphedema is an important clinical condition causing morbidity and is frequently encountered by the phlebologists. Elephantiasis Nostra is the status characterized with the extraordinary massive swelling of one or both legs with subsequent thickening and fibrosis of the overlying skin. It is an exaggerated manifestation of a longstanding chronic lymphedema. Etiologically, secondary lymphedema is caused by an external effect such as a chronic lymphangitis, removal of the lymph nodes, trauma, mechanical obstruction, radiotherapy, venous insufficiency, obesity, heart failure, bacterial or helminthic infection (Lymphatic Filariasis), in contrary to the primary lymphedema in which an inherent malfunction of lymphatic channels exists. A morbidly obese female patient with a bilateral Elephantiasis Nostra and our effort on setting the etiological definition and the treatment approach is presented.

Giacomini vein (GV) is an intersaphenous vein that connects lesser saphenous vein cranially to the greater saphenous vein tracking medial side of the leg. It is aimed to emphasize the importance of the diagnostic evaluation regarding the presence and compatibility of this cranial thigh extension of the lesser saphenous vein before planning the treatment modality in lower limb venous insufficiencies. In this case, an 18-year-old female patient diagnosed as an existence of an insufficient GV and the surgical treatment via extirpation of its small popliteal varicose tributary with isolated insufficiency, is presented.