Author: "MW" / Language: undetermined - Searchworks@Jio Institute Digital Library Search Results

4,186 results on '"MW"'

1. Evaluation of the toxicity of aqueous extracts of Aframomum melegueta, Picralima nitida, and Garcinia cola in Wistar rats

Author: TJB Kabongo, LA Luvingisa, MP Ngoie, MD Musuyu, MA Musunga, MW Kabamba, and PP Pyana
Subjects: General Medicine
Abstract: In order to determine the risks to human health associated with the use of certain medicinal plants, including Aframomum melegueta, Garcinia kola and Picralima nitida in a preclinical evaluation of the resistance, a pool of these three aqueous extracts was given once daily for ten days by gavage in Wistar rats. Haematological and biochemical analyzes after oral administration revealed a decrease in certain hepatic biomarkers such as glucose, Alanine Aminotransferase (ALT), etc., and renal biomarkers such as urea, creatinine, and creatinine kinase); increase in certain biomarkers such as Aspartate Transaminase (AST), an indicator of kidney and liver capacity.
Published: 2023

2. Anti sickling effect of Senna alexandrina, Aerva javanica , and Ficus palmata extracts on sickle cell disorder

Author: Yousef, Zahraa M Al, Alaswad, Elaf A, ElAssouli, M‑Zaki M, Nori, Dunya A, Filimban, Faten Z, Choudhry, Hani, Alam, Mohammad Z, Sadoun, Hadeel Al, and Helmi, Nawal MW
Subjects: Pharmaceutical Science, Pharmacology (medical), Sickle cell disease, Comet assay, Senna alexandrina, Antioxidant, RBC
Abstract: Purpose: To investigate the anti-sickling activity of Senna alexandrina, Aerva javanica, and Ficus palmate extracts. Methods: The leaves were extracted with water and methanol. The anti-sickling effect of extracts was determined using blood from 20 sickle cell disease (SCD) patients by mixing it with 500 and 1000 μg/mL of extract. The treated blood samples were then examined under a light microscope. The osmotic fragility of erythrocytes was determined using 4 mL (0 – 0.9 %) buffered saline mixed with 1 mL extract (500 μg/mL) and 0.05 mL sickled red blood cells (RBCs). Results: Aerva javanica extract significantly (p < 0.0001) reduced the percentage of sickle cells compared to control. The sickle-shaped cells were 29.47 % when treated with 125 μg/mL concentration of methanol extract of A. javanica that was further decreased to 0.35 % on increasing the concentration to 500 μg/mL. A similar trend was also observed with extracts of F. palmata. Extracts had protective effect on erythrocyte osmotic fragility. Results of comet assay suggested that extracts did not damage DNA. Conclusion: These plant extracts have promising anti-sickling activity and protect erythrocyte osmotic fragility. However, in vivo studies are required to validate these results and for further development of the extracts for therapeutic use.
Published: 2023

3. Application Tip and Concentration of a Self-mixing Bleach: Hydrogen Peroxide Inside the Pulp Chamber, Color Change, and Amount of Bleaching Gel Used

Author: TS Carneiro, MW Favoreto, LG Bernardi, MC Bandeca, CPF Borges, A Reis, and AD Loguercio
Subjects: General Dentistry
Abstract: SUMMARYPurposeThe objective of this study was to evaluate if the application method (tip with brush or tip without brush) and hydrogen peroxide (HP) concentration (6% or 35% self-mixing) of in-office bleaching gel influences the penetration of HP into the pulp chamber, color change, and the amount of bleaching gel used.MethodsForty healthy premolars were randomly divided into the following five groups (n=8): no treatment; HP6% using a tip with a brush, HP6% using a tip without a brush, HP35% using a tip with a brush, and HP35% using a tip without a brush. After treatments, the HP concentration (μg/mL) within the pulp chamber was determined using UV-Vis spectrophotometry. The color change (ΔEab, ΔE00, and ΔWID) was evaluated using a digital spectrophotometer. The amount of gel used (g) in each group was measured using a precision analytical balance. Data from each test were submitted to parametric tests (α=0.05).ResultsThe tip with a brush resulted in a lower amount of HP inside the pulp chamber and less gel used when compared with the tip without a brush, regardless of HP concentration (p0.05), a higher whitening effect was observed when the 6% HP was applied without a brush as opposed to with a tip brush (pConclusionsThe use of a tip with a brush, regardless of the in-office bleaching gel concentration (6% or 35% self-mixing), presented a lower penetration and lower volume of spent gel when compared to a tip without brush. However, the whitening effect depended on the concentration of HP used.
Published: 2023

4. Donor availability in the low resource environment: how can we deal with the challenges?

Author: Smid, MW, Ansah, JK, TayouTagny, C, Edirisinghe, L, Gunasekera, A, Owusu-Ofori, S, and Duits, A
Subjects: Cultural Studies, History, Literature and Literary Theory
Abstract: No abstract
Published: 2022

5. The JWST Early-release Science Program for Direct Observations of Exoplanetary Systems II: A 1 to 20 μm Spectrum of the Planetary-mass Companion VHS 1256-1257 b

Author: Miles, BE, Biller, BA, Patapis, P, Worthen, K, Rickman, E, Hoch, KKW, Skemer, A, Perrin, MD, Whiteford, N, Chen, CH, Sargent, B, Mukherjee, S, Morley, CV, Moran, SE, Bonnefoy, M, Petrus, S, Carter, AL, Choquet, E, Hinkley, S, Ward-Duong, K, Leisenring, JM, Millar-Blanchaer, MA, Pueyo, L, Ray, S, Sallum, S, Stapelfeldt, KR, Stone, JM, Wang, JJ, Absil, O, Balmer, WO, Boccaletti, A, Bonavita, M, Booth, M, Bowler, BP, Chauvin, G, Christiaens, V, Currie, T, Danielski, C, Fortney, JJ, Girard, JH, Grady, CA, Greenbaum, AZ, Henning, T, Hines, DC, Janson, M, Kalas, P, Kammerer, J, Kennedy, GM, Kenworthy, MA, Kervella, P, Lagage, PO, Lew, BWP, Liu, MC, Macintosh, B, Marino, S, Marley, MS, Marois, C, Matthews, EC, Matthews, BC, Mawet, D, McElwain, MW, Metchev, S, Meyer, MR, Molliere, P, Pantin, E, Quirrenbach, A, Rebollido, I, Ren, BB, Schneider, G, Vasist, M, Wyatt, MC, Zhou, Y, Briesemeister, ZW, Bryan, ML, Calissendorff, P, Cantalloube, F, Cugno, G, De Furio, M, Dupuy, TJ, Factor, SM, Faherty, JK, Fitzgerald, MP, Franson, K, Gonzales, EC, Hood, CE, Howe, AR, Kraus, AL, Kuzuhara, M, Lagrange, AM, Lawson, K, Lazzoni, C, Liu, P, Llop-Sayson, J, Lloyd, JP, Martinez, RA, Mazoyer, J, Quanz, SP, Redai, JA, Samland, M, Schlieder, JE, Miles, BE [0000-0002-5500-4602], Biller, BA [0000-0003-4614-7035], Patapis, P [0000-0001-8718-3732], Worthen, K [0000-0002-5885-5779], Rickman, E [0000-0003-4203-9715], Hoch, KKW [0000-0002-9803-8255], Skemer, A [0000-0001-6098-3924], Perrin, MD [0000-0002-3191-8151], Whiteford, N [0000-0001-8818-1544], Chen, CH [0000-0002-8382-0447], Sargent, B [0000-0001-9855-8261], Mukherjee, S [0000-0003-1622-1302], Morley, CV [0000-0002-4404-0456], Moran, SE [0000-0002-6721-3284], Bonnefoy, M [0000-0001-5579-5339], Petrus, S [0000-0003-0331-3654], Carter, AL [0000-0001-5365-4815], Choquet, E [0000-0002-9173-0740], Hinkley, S [0000-0001-8074-2562], Ward-Duong, K [0000-0002-4479-8291], Leisenring, JM [0000-0002-0834-6140], Millar-Blanchaer, MA [0000-0001-6205-9233], Ray, S [0000-0003-2259-3911], Sallum, S [0000-0001-6871-6775], Stapelfeldt, KR [0000-0002-2805-7338], Stone, JM [0000-0003-0454-3718], Wang, JJ [0000-0003-0774-6502], Absil, O [0000-0002-4006-6237], Balmer, WO [0000-0001-6396-8439], Boccaletti, A [0000-0001-9353-2724], Bonavita, M [0000-0002-7520-8389], Booth, M [0000-0001-8568-6336], Bowler, BP [0000-0003-2649-2288], Chauvin, G [0000-0003-4022-8598], Christiaens, V [0000-0002-0101-8814], Currie, T [0000-0002-7405-3119], Danielski, C [0000-0002-3729-2663], Fortney, JJ [0000-0002-9843-4354], Girard, JH [0000-0001-8627-0404], Greenbaum, AZ [0000-0002-7162-8036], Henning, T [0000-0002-1493-300X], Hines, DC [0000-0003-4653-6161], Janson, M [0000-0001-8345-593X], Kalas, P [0000-0002-6221-5360], Kammerer, J [0000-0003-2769-0438], Kennedy, GM [0000-0001-6831-7547], Kenworthy, MA [0000-0002-7064-8270], Kervella, P [0000-0003-0626-1749], Lew, BWP [0000-0003-1487-6452], Liu, MC [0000-0003-2232-7664], Macintosh, B [0000-0003-1212-7538], Marino, S [0000-0002-5352-2924], Marley, MS [0000-0002-5251-2943], Marois, C [0000-0002-4164-4182], Matthews, EC [0000-0003-0593-1560], Matthews, BC [0000-0003-3017-9577], Mawet, D [0000-0002-8895-4735], McElwain, MW [0000-0003-0241-8956], Metchev, S [0000-0003-3050-8203], Meyer, MR [0000-0003-1227-3084], Molliere, P [0000-0003-4096-7067], Pantin, E [0000-0001-6472-2844], Rebollido, I [0000-0002-4388-6417], Ren, BB [0000-0003-1698-9696], Schneider, G [0000-0002-4511-5966], Vasist, M [0000-0002-4511-3602], Wyatt, MC [0000-0001-9064-5598], Zhou, Y [0000-0003-2969-6040], Briesemeister, ZW [0000-0002-1764-2494], Bryan, ML [0000-0002-6076-5967], Calissendorff, P [0000-0002-5335-0616], Cantalloube, F [0000-0002-3968-3780], Cugno, G [0000-0001-7255-3251], De Furio, M [0000-0003-1863-4960], Dupuy, TJ [0000-0001-9823-1445], Factor, SM [0000-0002-8332-8516], Faherty, JK [0000-0001-6251-0573], Fitzgerald, MP [0000-0002-0176-8973], Franson, K [0000-0003-4557-414X], Gonzales, EC [0000-0003-4636-6676], Hood, CE [0000-0003-1150-7889], Howe, AR [0000-0002-4884-7150], Kraus, AL [0000-0001-9811-568X], Kuzuhara, M [0000-0002-4677-9182], Lawson, K [0000-0002-6964-8732], Lazzoni, C [0000-0001-7819-9003], Liu, P [0000-0001-7047-0874], Llop-Sayson, J [0000-0002-3414-784X], Martinez, RA [0000-0001-6301-896X], Mazoyer, J [0000-0002-9133-3091], Quanz, SP [0000-0003-3829-7412], Redai, JA [0000-0002-4489-3168], Samland, M [0000-0001-9992-4067], Schlieder, JE [0000-0001-5347-7062], and Apollo - University of Cambridge Repository
Subjects: The Solar System, Exoplanets, and Astrobiology, 5109 Space Sciences, 51 Physical Sciences
Abstract: We present the highest fidelity spectrum to date of a planetary-mass object. VHS 1256 b is a M Jup widely separated (∼8″, a = 150 au), young, planetary-mass companion that shares photometric colors and spectroscopic features with the directly imaged exoplanets HR 8799c, d, and e. As an L-to-T transition object, VHS 1256 b exists along the region of the color–magnitude diagram where substellar atmospheres transition from cloudy to clear. We observed VHS 1256 b with JWST's NIRSpec IFU and MIRI MRS modes for coverage from 1 to 20 μm at resolutions of ∼1000–3700. Water, methane, carbon monoxide, carbon dioxide, sodium, and potassium are observed in several portions of the JWST spectrum based on comparisons from template brown dwarf spectra, molecular opacities, and atmospheric models. The spectral shape of VHS 1256 b is influenced by disequilibrium chemistry and clouds. We directly detect silicate clouds, the first such detection reported for a planetary-mass companion.
Published: 2023

6. Effect of dried orange peel on egg production and quality of laying hen

Author: ST Ahmed, MM Hasan, SI Resmi, MW Islam, and M Rahman
Subjects: General Medicine
Abstract: Utilization of agricultural by-products in animal nutrition is a practice as old as the domestication of animals. The dried orange peel (DOP), by-product of citrus industry is a promising source of diversified bioactive ingredients with beneficial effects on health. Therefore, this study was carried out to assess the dietary effect of DOP on production and, internal and external egg quality characteristics of laying hens. A total of 60 layers of 25 weeks of age were segregated into three dietary treatment groups using a completely randomized design and reared up to 42 weeks. The dietary treatments were control (basal diet), 5% DOP (basal diet + 5% DOP), and 10% DOP (basal diet + 10% DOP). The study revealed that dietary DOP significantly decreased the feed consumption and feed conversion ratio of layers (p < 0.05) without having any significant effects on egg production, egg weight and egg mass. None of the exterior egg quality parameters were significantly affected by the dietary supplementation of DOP (p > 0.05). Among interior egg quality attributes, the albumen height, albumen index, yolk color, and Haugh unit were all considerably elevated through supplementation of 10% DOP (p < 0.05). Nevertheless, the yolk index was raised by both 5% and 10% DOP supplementation (p < 0.05). The relative weight of ovarian grape and oviduct did not affect by the supplementation of DOP with layer diet (p > 0.05). In summary, it may be said that layer diets can be supplemented with DOP up to 10% level to improve FCR, albumen index, yolk index, yolk color and Haugh unit without compromising egg production or exterior egg quality. Further studies are recommended with layer diets supplemented with DOP at levels higher than 10% to determine the ideal DOP dose during other production periods in various layer strains. Bangladesh Journal of Animal Science 51 (3): 98-106, 2022
Published: 2022

7. One-year results of minimally invasive fusion surgery of the sacroiliac joint as an alternative treatment after failed endoscopic thermal coagulation

Author: Osama Soliman, Robert Pflugmacher, Ernst MW Koch, Hesham Mohamed, Susanne van der Beck, Hany Abdallah, and Rahel Bornemann
Subjects: Analgesics, Opioid, Biomaterials, Spinal Fusion, Electrocoagulation, Biomedical Engineering, Biophysics, Humans, Sacroiliac Joint, Health Informatics, Bioengineering, Low Back Pain, Information Systems
Abstract: BACKGROUND: While pain in the severe sacroiliac joint (SIJ) is a common cause of lower back pain, SIJ disease is often overlooked as a diagnosis. OBJECTIVE: This study examines the extent of sufficient long-term pain relief and functional improvement in patients with SIJ syndrome that are treated with thermocoagulation. Some patients treated with thermocoagulation noted initial improvement, but the functionality and pain relief had limited duration and efficacy. Patients with insufficient improvement were recommended to undergo fusion surgery as an option for better and longer lasting results. METHOD: Patients with a long history of back or pelvic problems were selected for the study. Endoscopic thermal coagulation of the SIJ was carried out. The follow-up examinations took place after 1, 3, 6, 12 months. In patients with insufficient pain relief and functionality after thermocoagulation, a fusion surgery was performed. The results of the fusion surgery were documented over a 12-month follow-up period. To carry out the statistical evaluation visual analog scale (VAS), Oswestry-Disability-Index (ODI) and the consumption of opioids were recorded. RESULTS: Forty-eight patients were included. The mean VAS values 12 months after thermocoagulation were 68.9. The ODI after 12 months was very near or somewhat higher than their baseline prior to the thermocoagulation. Thus, a fusion surgery was recommended. Thirty-three patients agreed to the fusion operation. The VAS values 12 months after fusion surgery decreased to 53.1. Analogous to the VAS values, the Oswestry index (ODI) showed a significant improvement after the fusion operation. CONCLUSION: The success of surgical intervention in 88% of the SIJ syndrome patients with inadequate results 12 months after thermocoagulation proves the superiority of SIJ fusion surgery. This study showed long-lasting pain relief by an average of 65% and a median improvement in functional impairments of 60%. In view of these results, fusion surgery should be considered for patients without sufficient success of thermocoagulation.
Published: 2022

8. Adverse Effects of COVID-19 Vaccination: Machine Learning and Statistical Approach to Identify and Classify Incidences of Morbidity and Postvaccination Reactogenicity

Author: Ahamad, Md Martuza, Aktar, Sakifa, Uddin, Md Jamal, Rashed-Al-Mahfuz, Md, Azad, AKM, Uddin, Shahadat, Alyami, Salem A, Sarker, Iqbal H, Khan, Asaduzzaman, Liò, Pietro, Quinn, Julian MW, Moni, Mohammad Ali, Ahamad, Md Martuza [0000-0003-1640-6649], Aktar, Sakifa [0000-0001-8866-743X], Uddin, Md Jamal [0000-0001-8483-7059], Rashed-Al-Mahfuz, Md [0000-0001-7039-6176], Azad, AKM [0000-0002-5251-2214], Uddin, Shahadat [0000-0003-0091-6919], Alyami, Salem A [0000-0002-5507-9399], Sarker, Iqbal H [0000-0003-1740-5517], Khan, Asaduzzaman [0000-0003-4188-2065], Liò, Pietro [0000-0002-0540-5053], Quinn, Julian MW [0000-0001-9674-9646], Moni, Mohammad Ali [0000-0003-0756-1006], and Apollo - University of Cambridge Repository
Subjects: Heart disease, Leadership and Management, Health Informatics, Machine learning, computer.software_genre, comorbidities, Article, Health Information Management, statistical analysis, medicine, Medical history, adverse reactions, Adverse effect, Reactogenicity, COVID-19, vaccination, symptoms, machine learning, business.industry, Health Policy, Incidence (epidemiology), medicine.disease, Coronavirus, Vaccination, Infectious disease (medical specialty), Chills, Artificial intelligence, medicine.symptom, business, computer
Abstract: Peer reviewed: True, Good vaccine safety and reliability are essential for successfully countering infectious disease spread. A small but significant number of adverse reactions to COVID-19 vaccines have been reported. Here, we aim to identify possible common factors in such adverse reactions to enable strategies that reduce the incidence of such reactions by using patient data to classify and characterise those at risk. We examined patient medical histories and data documenting postvaccination effects and outcomes. The data analyses were conducted using a range of statistical approaches followed by a series of machine learning classification algorithms. In most cases, a group of similar features was significantly associated with poor patient reactions. These included patient prior illnesses, admission to hospitals and SARS-CoV-2 reinfection. The analyses indicated that patient age, gender, taking other medications, type-2 diabetes, hypertension, allergic history and heart disease are the most significant pre-existing factors associated with the risk of poor outcome. In addition, long duration of hospital treatments, dyspnoea, various kinds of pain, headache, cough, asthenia, and physical disability were the most significant clinical predictors. The machine learning classifiers that are trained with medical history were also able to predict patients with complication-free vaccination and have an accuracy score above 90%. Our study identifies profiles of individuals that may need extra monitoring and care (e.g., vaccination at a location with access to comprehensive clinical support) to reduce negative outcomes through classification approaches.
Published: 2023
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9. Experience and confidence in vaginal twin/breech delivery among trainees and junior specialists in Hong Kong public hospitals

Author: Ka-Yu Cheng, Hoi-Ki Chung, Catherine MW Hung, Ho-Ying Law, Yuen-Chung Tang, Pui-Ying Wong, Sani TK Wong, Francesca KY Lai, and Tsz-Kin Lo
Published: 2022

10. Impact of covid-19 on academic performance of students in the disadvantageous agricultural wetland (haor) areas of Bangladesh

Author: F Islam and MW Ahmed
Abstract: The pandemic COVID-19 has adverse impacts in almost every sector, including agriculture and education. As an agricultural country, Bangladesh Govt. have prioritized the livelihood, socio-economic condition, especially the education programs in the haor areas. This study aimed to assess the impact of COVID-19 on academic performances of primary to higher secondary students in the haor areas of Netrokona and Sunamganj districts. A total of 620 individuals took part in this study. All the participants thought their academic performance were affected by the COVID-19 pandemic in varying degrees. Half of the respondents had no opportunity to join online learning during school closures due to COVID-19 lockdown. The majority of online learners (61.54%) used software-based online classes, while a significant amount of students (39.74%) watched only government-provided Bangladesh Television (BTV) classes during the lockdown. Numerous problems regarding online learning, like financial crisis, lack of smart gadgets, expensive and slow internet, lack of training etc., were predominantly identified in haor areas. It is recommended that concerned authorities should take initiative to provide study loans, free or cheaper data packages, training to teachers and motivation to students and guardians to overcome the temporary loss of education in haor areas of Bangladesh. The findings of this study might help the educationists and policymakers to implement pandemic recovery programs for rural development in the agricultural region of the country. Bangladesh J. Agri. 2019-2021, 44-46: 115-125
Published: 2022

11. Effect of Foliar Application of Boron on the Yield And Quality of Potato

Author: MW Rahman, MM Islam, MS Alam, SM Sharifuzzaman, and MAK Mian
Subjects: General Earth and Planetary Sciences, General Environmental Science
Abstract: Foliar application of boron on the yield and storability of potato was evaluated at Breeder Seed Production Centre, Debiganj during two consecutive years 2013-14 and 2014-15. Six different concentration of boron such as: 0 ppm B (T1), 70 ppm B (T2), 140 ppm B (T3), 210 ppm B (T4), 280 ppm B (T5) and 350 ppm B (T6) were tested. The maximum yield 35.9 and 35.3 t ha-1 in 2013-14 and 2014-15, respectively was found when plants treated with 210 ppm B as foliar application (T4). The highest dry matter content of tuber was obtained from T4. T4 (210 ppm B) also showed the minimum rottage loss of tuber. The highest gross margin and marginal benefit cost ratio were recorded in the same treatment. Foliar application of 210 ppm B can be recommended for economically potato production in Tista Meander Floodplain Soil. Bangladesh J. Agril. Res. 45(2): 125-135, June 2020
Published: 2022

12. SARS-CoV-2-Specific T Cell Responses Are Not Associated with Protection against Reinfection in Hemodialysis Patients

Author: Shankar, S, Beckett, J, Tipton, T, Ogbe, A, Kasanyinga, M, Dold, C, Lumley, S, Dengu, F, Rompianesi, G, Elgilani, F, Longet, S, Deeks, A, Payne, RP, Duncan, CJA, Richter, A, de Silva, TI, Turtle, L, Bull, K, Barnardo, M, Friend, PJ, Dunachie, SJ, Hester, J, Issa, F, Barnes, E, Carroll, MW, Klenerman, P, Shankar, Sushma, Beckett, Joseph, Tipton, Tom, Ogbe, Ane, Kasanyinga, Mwila, Dold, Christina, Lumley, Sheila, Dengu, Fungai, Rompianesi, Gianluca, Elgilani, Faysal, Longet, Stephanie, Deeks, Alexandra, Payne, Rebecca P, Duncan, Christopher J A, Richter, Alex, de Silva, Thushan I, Turtle, Lance, Bull, Katherine, Barnardo, Martin, Friend, Peter J, Dunachie, Susanna J, Hester, Joanna, Issa, Fadi, Barnes, Eleanor, Carroll, Miles W, and Klenerman, Paul
Subjects: hemodialysi, Nephrology, Renal Dialysis, SARS-CoV-2, Reinfection, T-Lymphocytes, Research Letter, T cell, COVID-19, Humans, General Medicine, protection
Abstract: Patients on hemodialysis (HD) are vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and mount poor neutralizing antibody responses after two-dose vaccination. Although serological responses have been associated with reduced rates of reinfection, the relationship between cellular immunogenicity and protection has not been established. We report, for the first time, high incidence of reinfection in patients on HD who are vaccine naive (25%), which identifies that T cell responses do not predict protection against reinfection. Instead, patients on HD who went on to become reinfected had mounted highly variable and sometimes robust proliferative T cell responses to a broad array of SARS-CoV-2 peptide pools during the primary infection. The understanding that SARS-CoV-2–specific T cell responses are not predictive of protection against future infection will be a critical issue when measuring clinical efficacy of vaccination in these vulnerable cohorts, particularly when facing rapidly emerging variants of concern.
Published: 2023

13. Kinetic Turbulence in Collisionless High- β Plasmas

Author: Arzamasskiy, L, Kunz, MW, Squire, J, Quataert, E, and Schekochihin, AA
Subjects: Physics::Fluid Dynamics, High Energy Astrophysical Phenomena (astro-ph.HE), Plasma Physics (physics.plasm-ph), Astrophysics - Solar and Stellar Astrophysics, Physics::Space Physics, FOS: Physical sciences, General Physics and Astronomy, Astrophysics - High Energy Astrophysical Phenomena, Solar and Stellar Astrophysics (astro-ph.SR), Physics - Plasma Physics
Abstract: We present results from three-dimensional hybrid-kinetic simulations of Alfv\'enic turbulence in a high-beta, collisionless plasma. The key feature of such turbulence is the interplay between local wave--wave interactions between the fluctuations in the cascade and the non-local wave-particle interactions associated with kinetic micro-instabilities driven by anisotropy in the thermal pressure (namely, firehose, mirror, and ion-cyclotron). We present theoretical estimates for, and calculate directly from the simulations, the effective collisionality and plasma viscosity in pressure-anisotropic high-beta turbulence, demonstrating that, for strong Alfv\'enic turbulence, the effective parallel-viscous scale is comparable to the driving scale of the cascade. Below this scale, the kinetic-energy spectrum indicates an Alfv\'enic cascade with a slope steeper than $-5/3$ due to the anisotropic viscous stress. The magnetic-energy spectrum is shallower than $-5/3$ near the ion-Larmor scale due to fluctuations produced by the firehose instability. Most of the cascade energy (80-90%) is dissipated as ion heating through a combination of Landau damping and anisotropic viscous heating. Our results have implications for models of particle heating in low-luminosity accretion onto supermassive black holes, the effective viscosity of the intracluster medium, and the interpretation of near-Earth solar-wind observations., Comment: 34 pages, 19 figures, accepted to PRX
Published: 2023

14. Efficacy of pharmacological and interventional treatment for resistant hypertension-a network meta-analysis

Author: Zhejia Tian, Clara Vollmer Barbosa, Hannah Lang, Johann Bauersachs, Anette Melk, and Bernhard MW Schmidt
Abstract: BackgroundResistant hypertension is associated with a high risk of cardiovascular disease, chronic kidney disease and mortality. Yet, its management is challenging. This study aims to establish the comparative effectiveness of pharmacologic and interventional treatments by conducting a network meta-analysis.MethodsMEDLINE, Cochrane Register of Controlled Trials and Web of Science Core Collection were systematically searched in March 2022. Randomized controlled trials comparing treatment options for management of resistant hypertension were included. Outcomes were blood pressure changes, measured in the office and in 24h ambulatory blood pressure measurement. We applied a frequentist random effects model to perform a network meta-analysis combining placebo medication and sham procedure as the reference comparator.ResultsFrom 4771 records, 24 studies met the inclusion criteria with 3458 included patients in total. 12 active treatment alternatives were analyzed. Among all comparators, spironolactone had the highest-ranking probability and was considered the most effective treatment to reduce office systolic blood pressure (−13.30 mmHg [−17.89; −8.72];P< 0.0001) and 24h systolic blood pressure (−8.46 mmHg [−12.54; −4.38]; P < 0.0001) in patients with resistant hypertension.ConclusionAmong all pharmacologic and interventional treatments, spironolactone is the most effective in reducing office and 24h systolic blood pressure in patients with resistant hypertension. More comparative trials and especially trials with long-term follow up are needed.Graphical Abstract
Published: 2023

15. Entity matching across stereo cameras for tracking construction workers

Author: Lee, YJ, Park, MW, and Brilakis, I
Abstract: While GPS and RFID are dominantly used for tracking construction equipment and materials, 3D vision-based tracking that employs stereo-vision system has been also proposed as an alternative to efficiently track construction resources operating in a congested site. The 3D vision-based tracking requires an entity to be tracked in both cameras of the stereovision system so that two of 2D pixel coordinates are generated for each entity. Its 3D coordinate can be calculated by triangulating two projection rays that go through the 2D pixel coordinates. In order to track multiple entities of the same type simultaneously, the triangulation requires an additional process to match entities across the two camera views. This paper proposes an efficient method of entity matching for tracking construction workers. The method is mainly based on epipolar geometry which represents the geometric relation between two camera views. Two additional strategies - distance ratio thresholding and frame grouping - are introduced to reject false matchings and to ultimately increase precision of the 3D tracking. Experiment results demonstrate its suitability for automated entity matching for 3D vision-based tracking of construction workers.
Published: 2023
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16. The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection

Author: Goldswain, H, Dong, X, Penrice-Randal, R, Alruwaili, M, Shawli, GT, Prince, T, Williamson, MK, Raghwani, J, Randle, N, Jones, B, Donovan-Banfield, I, Salguero, FJ, Tree, JA, Hall, Y, Hartley, C, Erdmann, M, Bazire, J, Jearanaiwitayakul, T, Semple, MG, Openshaw, PJM, Baillie, JK, ISARIC4C Investigators, Emmett, SR, Digard, P, Matthews, DA, Turtle, L, Darby, AC, Davidson, AD, Carroll, MW, Hiscox, JA, Hiscox, Julian A [0000-0002-6582-0275], and Apollo - University of Cambridge Repository
Subjects: P323L, NSP12, SARS-CoV-2, Evolution, Mutation, COVID-19, Humans, Genome, Viral, Spike protein, Genetic Background, Pandemics, Selection, Polymerase
Abstract: BACKGROUND: The mutational landscape of SARS-CoV-2 varies at the dominant viral genome sequence and minor genomic variant population. During the COVID-19 pandemic, an early substitution in the genome was the D614G change in the spike protein, associated with an increase in transmissibility. Genomes with D614G are accompanied by a P323L substitution in the viral polymerase (NSP12). However, P323L is not thought to be under strong selective pressure. RESULTS: Investigation of P323L/D614G substitutions in the population shows rapid emergence during the containment phase and early surge phase during the first wave. These substitutions emerge from minor genomic variants which become dominant viral genome sequence. This is investigated in vivo and in vitro using SARS-CoV-2 with P323 and D614 in the dominant genome sequence and L323 and G614 in the minor variant population. During infection, there is rapid selection of L323 into the dominant viral genome sequence but not G614. Reverse genetics is used to create two viruses (either P323 or L323) with the same genetic background. L323 shows greater abundance of viral RNA and proteins and a smaller plaque morphology than P323. CONCLUSIONS: These data suggest that P323L is an important contribution in the emergence of variants with transmission advantages. Sequence analysis of viral populations suggests it may be possible to predict the emergence of a new variant based on tracking the frequency of minor variant genomes. The ability to predict an emerging variant of SARS-CoV-2 in the global landscape may aid in the evaluation of medical countermeasures and non-pharmaceutical interventions.
Published: 2023

17. Circulating PACAP levels are associated with increased amygdala-default mode network resting-state connectivity in posttraumatic stress disorder

Author: KJ Clancy, Q Devignes, P Kumar, V May, SE Hammack, E Akman, EJ Casteen, CD Pernia, SA Jobson, MW Lewis, NP Daskalakis, WA Carlezon, KJ Ressler, SL Rauch, and IM Rosso
Abstract: The pituitary adenylate cyclase-activating polypeptide (PACAP) system is implicated in posttraumatic stress disorder (PTSD) and related amygdala-mediated arousal and threat reactivity. PTSD is characterized by increased amygdala reactivity to threat and, more recently, aberrant intrinsic connectivity of the amygdala with large-scale resting state networks, specifically the default mode network (DMN). While the influence of PACAP on amygdala reactivity has been described, its association with intrinsic amygdala connectivity remains unknown. To fill this gap, we examined functional connectivity of resting-state functional magnetic resonance imaging (fMRI) in eighty-nine trauma-exposed adults (69 female) screened for PTSD symptoms to examine the association between blood-borne (circulating) PACAP levels and amygdala-DMN connectivity. Higher circulating PACAP levels were associated with increased amygdala connectivity with posterior DMN regions, including the posterior cingulate cortex/precuneus (PCC/Precun) and left angular gyrus (lANG). Consistent with prior work, this effect was seen in female, but not male, participants and the centromedial, but not basolateral, subregions of the amygdala. Clinical association analyses linked amygdala-PCC/Precun connectivity to anxious arousal symptoms, specifically exaggerated startle response. Taken together, our findings converge with previously demonstrated effects of PACAP on amygdala activity in PTSD-related processes and offer novel evidence for an association between PACAP and intrinsic amygdala connectivity patterns in PTSD. Moreover, these data provide preliminary evidence to motivate future work ascertaining the sex- and subregion-specificity of these effects. Such findings may enable novel mechanistic insights into neural circuit dysfunction in PTSD and how the PACAP system confers risk through a disruption of intrinsic resting-state network dynamics.
Published: 2023

18. Deep learning–based time-of-flight (ToF) image enhancement of non-ToF PET scans

Author: Mehranian, A, Wollenweber, SD, Walker, MD, Bradley, KM, Fielding, P, Huellner, MW, Kotasidis, F, Su, K, Johnsen, R, Jansen, F, and McGowan, DR
Subjects: Deep Learning, Fluorodeoxyglucose F18, Positron Emission Tomography Computed Tomography, Positron-Emission Tomography, Image Processing, Computer-Assisted, Humans, Radiology, Nuclear Medicine and imaging, General Medicine, Tomography, X-Ray Computed, Algorithms
Abstract: Purpose To improve the quantitative accuracy and diagnostic confidence of PET images reconstructed without time-of-flight (ToF) using deep learning models trained for ToF image enhancement (DL-ToF). Methods A total of 273 [18F]-FDG PET scans were used, including data from 6 centres equipped with GE Discovery MI ToF scanners. PET data were reconstructed using the block-sequential-regularised-expectation–maximisation (BSREM) algorithm with and without ToF. The images were then split into training (n = 208), validation (n = 15), and testing (n = 50) sets. Three DL-ToF models were trained to transform non-ToF BSREM images to their target ToF images with different levels of DL-ToF strength (low, medium, high). The models were objectively evaluated using the testing set based on standardised uptake value (SUV) in 139 identified lesions, and in normal regions of liver and lungs. Three radiologists subjectively rated the models using testing sets based on lesion detectability, diagnostic confidence, and image noise/quality. Results The non-ToF, DL-ToF low, medium, and high methods resulted in − 28 ± 18, − 28 ± 19, − 8 ± 22, and 1.7 ± 24% differences (mean; SD) in the SUVmaxfor the lesions in testing set, compared to ToF-BSREM image. In background lung VOIs, the SUVmeandifferences were 7 ± 15, 0.6 ± 12, 1 ± 13, and 1 ± 11% respectively. In normal liver, SUVmeandifferences were 4 ± 5, 0.7 ± 4, 0.8 ± 4, and 0.1 ± 4%. Visual inspection showed that our DL-ToF improved feature sharpness and convergence towards ToF reconstruction. Blinded clinical readings of testing sets for diagnostic confidence (scale 0–5) showed that non-ToF, DL-ToF low, medium, and high, and ToF images scored 3.0, 3.0,4.1, 3.8, and 3.5 respectively. For this set of images, DL-ToF medium therefore scored highest for diagnostic confidence. Conclusion Deep learning–based image enhancement models may provide converged ToF-equivalent image quality without ToF reconstruction. In clinical scoring DL-ToF-enhanced non-ToF images (medium and high) on average scored as high as, or higher than, ToF images. The model is generalisable and hence, could be applied to non-ToF images from BGO-based PET/CT scanners.
Published: 2022

19. Income moderates changes in big-five personality traits across eighteen years

Author: Vincent YS Oh, Ismaharif Ismail, and Eddie MW Tong
Subjects: Social Psychology, sense organs
Abstract: The role of income in adult personality change remains poorly understood. Using latent growth modeling, we performed exploratory analyses of how longitudinal trajectories of change in personal income and the Big Five personality traits would be related. We examined 4234 participants (2149 Males, 2085 Females; MT1age = 46.42, SDT1age = 13.36, age range at T1: 20–74 years) across three time points spanning 18 years using data from the Midlife in the United States study. Results indicated that starting levels of income moderated changes in four personality traits. Specifically, income moderated the slopes of openness to experience, extraversion, agreeableness, and neuroticism, such that for high-income individuals, openness to experience, extraversion, and agreeableness were less likely to decline and more likely to either increase or remain stable over time, while neuroticism was less likely to increase and more likely to remain stable over time. Conversely, personality traits were weaker predictors of income change as slopes of income were not moderated by starting levels of any of the personality traits. Moreover, changes in income were not correlated with changes in any of the personality traits. The findings suggest that individual differences in income could potentially explain diverging trajectories of personality change.
Published: 2022

20. Sonali chicken farming in southern part of Bangladesh

Author: S Howlader, MM Hasan, SI Resmi, MW Islam, M Rahman, and ST Ahmed
Subjects: General Medicine
Abstract: The study was conducted to identify the socio-economic status and problems faced by the Sonali farmers at Wazirpur Upazila in Barishal District. A total of 90 respondents from 9 unions were selected randomly for primary data collection. The farmers and their farming were evaluated through the analysis of data collected in a pre-structured questionnaire. This study revealed that a maximum portion of the farmers were middle-aged (52.2%), male (92.2%), and had a secondary level of education (54.4%). Most farmers had medium-sized farm (38.9%) and invested their own capital in farming (54.9%). Although major farmers had low experience in Sonali chicken farming, they had high management skills (63.9%). In terms of occupation, the highest percentage of farmers (38.9%) had a conjugated occupation of poultry and crop. Most of the farmers had their own tube-well (74.7%) and use sanitary latrine (71.1%). Nevertheless, only 17% of the farmers had good health condition. About 49% of the farmers had only one chicken house, and 87.8% followed the floor system for rearing Sonali chicken. Surprisingly, all the farms followed an all-in-all-out marketing system for Sonali chicken. Most of the farmers (96.7%) vaccinated their poultry birds and added coccidiostat (73.3%) and vitamin mineral premix (94.4%) to the feed. A major portion of the farmers identified the irregular fluctuation in the market price of feeds (95.6%) and day-old chicks (93.3%) as severe problem, followed by high price of feed but low price of meat (87.8%). A disorganized marketing channel was the next major problem faced by the poultry farmers (83.3%). Taken together, the Sonali farmers of Barishal were middle-aged; poorly educated, and invested their own capital for farming, and they faced a variety of challenges during farming and marketing their chickens. To enhance Sonali farmers’ socio-economic conditions and alleviate their problems, the government should take appropriate steps to provide finance and farm-based training, including modern animal husbandry practices. Bangladesh Journal of Animal Science. 2022. 51 (1): 1-11
Published: 2022

21. Pemanfaatan Hasil Sumber Daya Tani Sebagai Inovasi Cabai di Desa Nyiur Tebel Kecamatan Sukamulia Kabupaten Lombok Timur

Author: null Muh. Zubair, null Fikri, null Tegar Humam Rafii, null Sepriadi MW, null Muhamad Faizi Rahman, null I Nengah Suardika, null Nurul Fikria Sagitarini, null Nisfi Sya’bani Karima, null Nanda Meilani Putri, null Baiq Mila Angriani, null Sarmila, and null Erna Widiarty
Abstract: Desa Nyiur Tebel merupakan Desa yang memiliki sumber daya alam Petani yang berlimpah, salah satu sumber daya Tani yaitu Cabai. Kurangnya penerapkan sistem pascapanen di Masyarakat diakibatkan karena kurangnya pengetahuan yang terbatas pada Masyarakat, sehingga muncul suatu Inovasi Baru terhadap sumber daya alam Cabai. Inovasi cabai bertujuan untuk menumbuhkan dan meningkatkan Perekonomian Masyarakat Desa Nyiur Tebel. Produk Inovasi baru dibuat dengan dua macam produk cabai yaitu Sambal Kering dan Bubuk Cabai, dimana produk tersebut dibuat tanpa bahan pengawet dan telah dipasarkan pada unit – unit usaha dagang di Desa Nyiur Tebel.
Published: 2022

22. Optimization of Slaughter Age of Jamuna Basin Lamb Based on Carcass Traits and Meat Quality

Author: MA Hossain, MM Rahman, MW Rahman, MM Hossain, and MA Hashem
Subjects: Industrial and Manufacturing Engineering
Abstract: The aim of this study was to identify optimum slaughter age on carcass traits and meat quality of Jamuna basin lambs. Thirty lambs were divided into three age groups like T1 (6 months), T2 (9 months) and T3 (12 months) having ten lambs of each treatment. Parameters studied were carcass traits, proximate component (DM, CP, EE, and Ash), physicochemical (Ultimate pH, cooked pH, cooking loss, drip loss, water holding capacity-WHC), sensory attributes (color, flavor, tenderness, juiciness, overall acceptability) and instrumental color values (L*, a* and b*). Hot carcass weight and dressing% were found significantly (p
Published: 2022

23. Constraints on the CKM angle γ from B± → Dh± decays using D → h±h′∓π0 final states

Author: Aaij, R, Abdelmotteleb, Asw, Beteta, Ca, Gallego, Fja, Ackernley, T, Adeva, B, Adinolfi, M, Afsharnia, H, Agapopoulou, C, Aidala, Ca, Aiola, S, Ajaltouni, Z, Akar, S, Albrecht, J, Alessio, F, Alexander, M, Alfonso Albero, A, Aliouche, Z, Alkhazov, G, Cartelle, Pa, Amato, S, Amey, Jl, Amhis, Y, An, L, Anderlini, L, Andersson, N, Andreianov, A, Andreotti, M, Archilli, F, Artamonov, A, Artuso, M, Arzymatov, K, Aslanides, E, Atzeni, M, Audurier, B, Bachmann, S, Bachmayer, M, Back, Jj, Baladron Rodriguez, P, Balagura, V, Baldini, W, Leite, Jb, Barbetti, M, Barlow, Rj, Barsuk, S, Barter, W, Bartolini, M, Baryshnikov, F, Basels, Jm, Bashir, S, Bassi, G, Batsukh, B, Battig, A, Bay, A, Beck, A, Becker, M, Bedeschi, F, Bediaga, I, Beiter, A, Belavin, V, Belin, S, Bellee, V, Belous, K, Belov, I, Belyaev, I, Bencivenni, G, Ben-Haim, E, Berezhnoy, A, Bernet, R, Berninghoff, D, Bernstein, Hc, Bertella, C, Bertolin, A, Betancourt, C, Betti, F, Bezshyiko, I, Bhasin, S, Bhom, J, Bian, L, Bieker, Ms, Biesuz, N, V, Bifani, S, Billoir, P, Biolchini, A, Birch, M, Bishop, Fcr, Bitadze, A, Bizzeti, A, Bjorn, M, Blago, Mp, Blake, T, Blanc, F, Blusk, S, Bobulska, D, Boelhauve, Ja, Boente Garcia, O, Boettcher, T, Boldyrev, A, Bondar, A, Bondar, N, Borghi, S, Borisyak, M, Borsato, M, Borsuk, Jt, Bouchiba, Sa, Bowcock, Tj, Boyer, A, Bozzi, C, Bradley, Mj, Braun, S, Brea Rodriguez, A, Brodzicka, J, Gonzalo, Ab, Brundu, D, Buonaura, A, Buonincontri, L, Burke, At, Burr, C, Bursche, A, Butkevich, A, Butter, Js, Buytaert, J, Byczynski, W, Cadeddu, S, Cai, H, Calabrese, R, Calefice, L, Cali, S, Calladine, R, Calvi, M, Calvo Gomez, M, Magalhaes, Pc, Campana, P, Quezada, Afc, Capelli, S, Capriotti, L, Carbone, A, Carboni, G, Cardinale, R, Cardini, A, Carli, I, Carniti, P, Carus, L, Akiba, Kc, Casais Vidal, A, Caspary, R, Casse, G, Cattaneo, M, Cavallero, G, Celani, S, Cerasoli, J, Cervenkov, D, Chadwick, Aj, Chapman, Mg, Charles, M, Charpentier, P, Chatzikonstantinidis, G, Barajas, Cac, Chefdeville, M, Chen, C, Chen, S, Chernov, A, Chobanova, V, Cholak, S, Chrzaszcz, M, Chubykin, A, Chulikov, V, Ciambrone, P, Cicala, Mf, Vidal, Xc, Ciezarek, G, Clarke, Pel, Clemencic, M, Cliff, H, Closier, J, Cobbledick, Jl, Coco, V, Coelho, Jab, Cogan, J, Cogneras, E, Cojocariu, L, Collins, P, Colombo, T, Congedo, L, Contu, A, Cooke, N, Coombs, G, Corredoira, I, Corti, G, Sobral, Cmc, Couturier, B, Craik, Dc, Crkovska, J, Torres, Mc, Currie, R, Da Silva, Cl, Dadabaev, S, Dai, L, Dall'Occo, E, Dalseno, J, D'Ambrosio, C, Danilina, A, D'Argent, P, Dashkina, A, Davies, Je, Davis, A, Francisco, Oda, De Bruyn, K, De Capua, S, De Cian, M, De Lucia, E, De Miranda, Jm, De Paula, L, De Serio, M, De Simone, D, De Simone, P, De Vellis, F, de Vries, Ja, Dean, Ct, Debernardis, F, Decamp, D, Dedu, V, Del Buono, L, Delaney, B, Dembinski, H, Dendek, A, Denysenko, V, Derkach, D, Deschamps, O, Desse, F, Dettori, F, Dey, B, Di Cicco, A, Di Nezza, P, Didenko, S, Dieste Maronas, L, Dijkstra, H, Dobishuk, V, Dong, C, Donohoe, Am, Dordei, F, dos Reis, Ac, Douglas, L, Dovbnya, A, Downes, Ag, Dudek, Mw, Dufour, L, Duk, V, Durante, P, Durham, Jm, Dutta, D, Dziurda, A, Dzyuba, A, Easo, S, Egede, U, Egorychev, V, Eidelman, S, Eisenhardt, S, Ek-In, S, Eklund, L, Ely, S, Ene, A, Epple, E, Escher, S, Eschle, J, Esen, S, Evans, T, Falcao, Ln, Fan, Y, Fang, B, Farry, S, Fazzini, D, Feo, M, Fernandez Prieto, A, Fernez, Ad, Ferrari, F, Lopes, Lf, Rodrigues, Ff, Sole, Sf, Ferrillo, M, Ferro-Luzzi, M, Filippov, S, Fini, Ra, Fiorini, M, Firlej, M, Fischer, Km, Fitzgerald, Ds, Fitzpatrick, C, Fiutowski, T, Fkiaras, A, Fleuret, F, Fontana, M, Fontanelli, F, Forty, R, Foulds-Holt, D, Lima, Vf, Sevilla, Mf, Frank, M, Franzoso, E, Frau, G, Frei, C, Friday, Da, Fu, J, Fuehring, Q, Gabriel, E, Galati, G, Gallas Torreira, A, Galli, D, Gambetta, S, Gan, Y, Gandelman, M, Gandini, P, Gao, Y, Garau, M, Martin, Lmg, Garcia Moreno, P, Pardinas, Jg, Garcia Plana, B, Garcia Rosales, Fa, Garrido, L, Gaspar, C, Geertsema, Re, Gerick, D, Gerken, Ll, Gersabeck, E, Gersabeck, M, Gershon, T, Gerstel, D, Giambastiani, L, Gibson, V, Giemza, Hk, Gilman, Al, Giovannetti, M, Gioventu, A, Gironella Gironell, P, Giugliano, C, Gizdov, K, Gkougkousis, El, Gligorov, Vv, Gobel, C, Golobardes, E, Golubkov, D, Golutvin, A, Gomes, A, Gomez Fernandez, S, Abrantes, Fg, Goncerz, M, Gong, G, Gorbounov, P, Gorelov, I, Gotti, C, Govorkova, E, Grabowski, Jp, Grammatico, T, Cardoso, Lag, Grauges, E, Graverini, E, Graziani, G, Grecu, A, Greeven, Lm, Grieser, Na, Grillo, L, Gromov, S, Cazon, Brg, Gu, C, Guarise, M, Guittiere, M, Guenther, Pa, Gushchin, E, Guth, A, Guz, Y, Gys, T, Hadavizadeh, T, Haefeli, G, Haen, C, Haimberger, J, Halewood-leagas, T, Hamilton, Pm, Hammerich, Jp, Han, Q, Han, X, Hancock, Th, Hansen, Eb, Hansmann-Menzemer, S, Harnew, N, Harrison, T, Hasse, C, Hatch, M, He, J, Hecker, M, Heijhoff, K, Heinicke, K, Henderson, Rdl, Hennequin, Am, Hennessy, K, Henry, L, Heuel, J, Hicheur, A, Hill, D, Hilton, M, Hollitt, Se, Hou, R, Hou, Y, Hu, J, Hu, W, Hu, X, Huang, W, Huang, X, Hulsbergen, W, Hunter, Rj, Hushchyn, M, Hutchcroft, D, Hynds, D, Ibis, P, Idzik, M, Ilin, D, Ilten, P, Inglessi, A, Ishteev, A, Ivshin, K, Jacobsson, R, Jage, H, Jakobsen, S, Jans, E, Jashal, Bk, Jawahery, A, Jevtic, V, Jiang, X, John, M, Johnson, D, Jones, Cr, Jones, Tp, Jost, B, Jurik, N, Kadavath, Shk, Kandybei, S, Kang, Y, Karacson, M, Karpov, M, Kautz, Jw, Keizer, F, Keller, Dm, Kenzie, M, Ketel, T, Khanji, B, Kharisova, A, Kholodenko, S, Kirn, T, Kirsebom, Vs, Kitouni, O, Klaver, S, Kleijne, N, Klimaszewski, K, Kmiec, Mr, Koliiev, S, Kondybayeva, A, Konoplyannikov, A, Kopciewicz, P, Kopecna, R, Koppenburg, P, Korolev, M, Kostiuk, I, Kot, O, Kotriakhova, S, Kravchenko, P, Kravchuk, L, Krawczyk, Rd, Kreps, M, Kress, F, Kretzschmar, S, Krokovny, P, Krupa, W, Krzemien, W, Kubat, J, Kucharczyk, M, Kudryavtsev, V, Kuindersma, Hs, Kunde, Gj, Kvaratskheliya, T, Lacarrere, D, Lafferty, G, Lai, A, Lampis, A, Lancierini, D, Lane, Jj, Lane, R, Lanfranchi, G, Langenbruch, C, Langer, J, Lantwin, O, Latham, T, Lazzari, F, Le Gac, R, Lee, Sh, Lefevre, R, Leflat, A, Legotin, S, Leroy, O, Lesiak, T, Leverington, B, Li, H, Li, P, Li, S, Li, Y, Li, Z, Liang, X, Lin, T, Lindner, R, Lisovskyi, V, Litvinov, R, Liu, G, Liu, H, Liu, Q, Liu, S, Lobo Salvia, A, Loi, A, Lomba Castro, J, Longstaff, I, Lopes, Jh, Lopez Solino, S, Lovell, Gh, Lu, Y, Lucarelli, C, Lucchesi, D, Luchuk, S, Martinez, Ml, Lukashenko, V, Luo, Y, Lupato, A, Luppi, E, Lupton, O, Lusiani, A, Lyu, X, Ma, L, Ma, R, Maccolini, S, Machefert, F, Maciuc, F, Macko, V, Mackowiak, P, Maddrell-Mander, S, Madejczyk, O, Mohan, Lrm, Maev, O, Maevskiy, A, Majewski, Mw, Malczewski, Jj, Malde, S, Malecki, B, Malinin, A, Maltsev, T, Malygina, H, Manca, G, Mancinelli, G, Manuzzi, D, Marangotto, D, Maratas, J, Marchand, Jf, Marconi, U, Mariani, S, Benito, Cm, Marinangeli, M, Marks, J, Marshall, Am, Marshall, Pj, Martelli, G, Martellotti, G, Martinazzoli, L, Martinelli, M, Martinez Santos, D, Martinez Vidal, F, Massafferri, A, Materok, M, Matev, R, Mathad, A, Matiunin, V, Matteuzzi, C, Mattioli, Kr, Mauri, A, Maurice, E, Mauricio, J, Mazurek, M, Mccann, M, Mcconnell, L, Mcgrath, Th, Mchugh, Nt, Mcnab, A, Mcnulty, R, Mead, J, Meadows, B, Meier, G, Melnychuk, D, Meloni, S, Merk, M, Merli, A, Garcia, Lm, Mikhasenko, M, Milanes, Da, Millard, E, Milovanovic, M, Minard, M, Minotti, A, Minzoni, L, Mitchell, Se, Mitreska, B, Mitzel, Ds, Modden, A, Mohammed, Ra, Moise, Rd, Mokhnenko, S, Mombacher, T, Monroy, Ia, Monteil, S, Morandin, M, Morello, G, Morello, Mj, Moron, J, Morris, Ab, Morris, Ag, Mountain, R, Mu, H, Muheim, F, Mulder, M, Mueller, D, Mueller, K, Murphy, Ch, Murray, D, Murta, R, Muzzetto, P, Naik, P, Nakada, T, Nandakumar, R, Nanut, T, Nasteva, I, Needham, M, Neri, N, Neubert, S, Neufeld, N, Newcombe, R, Niel, Em, Nieswand, S, Nikitin, N, Nolte, Ns, Normand, C, Nunez, C, Oblakowska-Mucha, A, Obraztsov, V, Oeser, T, O'Hanlon, Dp, 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E., Yin, H., Yu, J., Yuan, X., Yushchenko, O., Zaffaroni, E., Zavertyaev, M., Zdybal, M., Zenaiev, O., Zeng, M., Zhang, D., Zhang, L., Zhang, S., Zhang, Y., Zharkova, A., Zhelezov, A., Zheng, Y., Zhou, T., Zhou, X., Zhou, Y., Zhu, X., Zhu, Z., Zonneveld, J. B., Zou, Q., Zucchelli, S., Zuliani, D., Zunica, G., Abdelmotteleb, A.S.W., Abellán Beteta, C., Abudinén, F., Aidala, C.A., Alvarez Cartelle, P., Amey, J.L., Andersson, M., Back, J.J., Balagura, V., Baptista de Souza Leite, J., Barlow, R.J., Basels, J.M., Bediaga, I., Belavin, V., Bellee, V., Belov, I., Belyaev, I., Bernstein, H.C., Bezshyiko, Ia., Bieker, M.S., Biesuz, N.V., Bishop, F.C.R., Bjørn, M., Blago, M.P., Boelhauve, J.A., Borsuk, J.T., Bouchiba, S.A., Bowcock, T.J.V., Bradley, M.J., Brossa Gonzalo, A., Burke, A.T., Butter, J.S., Camargo Magalhaes, P., Campoverde Quezada, A.F., Carli, I., Carvalho Akiba, K., Chadwick, A.J., Chapman, M.G., Charpentier, Ph., Chavez Barajas, C.A., Chobanova, V., Chulikov, V., Cicala, M.F., Cid Vidal, X., Clarke, P.E.L., Cliff, H.V., Cobbledick, J.L., Coco, V., Coelho, J.A.B., Corredoira, I., Costa Sobral, C.M., Craik, D.C., Crkovská, J., Cruz Torres, M., Da Silva, C.L., d'Argent, P., Davies, J.E., De Aguiar Francisco, O., De Miranda, J.M., de Vries, J.A., Dean, C.T., Dedu, V., Dembinski, H.-P., Denysenko, V., Dobishuk, V., Donohoe, A.M., dos Reis, A.C., Downes, A.G., Dudek, M.W., Duk, V., Durham, J.M., Egorychev, V., Falcao, L.N., Féo, M., Fernez, A.D., Ferreira Lopes, L., Ferreira Rodrigues, F., Ferreres Sole, S., Fini, R.A., Fischer, K.M., Fitzgerald, D.S., Franco Lima, V., Franco Sevilla, M., Friday, D.A., Garcia Martin, L.M., García Pardiñas, J., Garcia Rosales, F.A., Geertsema, R.E., Gerken, L.L., Gibson, V., Giemza, H.K., Gilman, A.L., Gioventù, A., Gkougkousis, E.L., Gligorov, V.V., Göbel, C., Goncalves Abrantes, F., Gorelov, I.V., Grabowski, J.P., Granado Cardoso, L.A., Graugés, E., Greeven, L.M., Grieser, N.A., Gruberg Cazon, B.R., Günther, P. A., Hamilton, P.M., Hammerich, J.P., Hancock, T.H., Hansen, E.B., Henderson, R.D.L., Hennequin, A.M., Hollitt, S.E., Hunter, R.J., Jashal, B.K., Jevtic, V., Jones, C.R., Jones, T.P., Kautz, J.W., Keller, D.M., Kirsebom, V.S., Kmiec, M.R., Kostiuk, I., Krawczyk, R.D., Kudryavtsev, V., Kuindersma, H.S., Kunde, G.J., Lane, J.J., Lee, S.H., Lefèvre, R., Lisovskyi, V., Longstaff, I., Lopes, J.H., López Soliño, S., Lovell, G.H., Lucio Martinez, M., Lukashenko, V., Lusiani, A., Macko, V., Madhan Mohan, L.R., Majewski, M.W., Malczewski, J.J., Marchand, J.F., Marin Benito, C., Marshall, A.M., Marshall, P.J., Matiunin, V., Mattioli, K.R., McCann, M., Mcgrath, T.H., Mchugh, N.T., McNab, A., McNulty, R., Mead, J.V., Meyer Garcia, L., Milanes, D.A., Minard, M.-N., Mitchell, S.E., Mitzel, D.S., Mödden, A., Mohammed, R.A., Moise, R.D., Mombächer, T., Monroy, I.A., Morello, M.J., Morris, A.B., Morris, A.G., Müller, D., Müller, K., Murphy, C.H., Nasteva, I., Niel, E.M., Nolte, N.S., Obraztsov, V., O'Hanlon, D.P., Olivares, M.E., Onderwater, C.J.G., O'Neil, R.H., Otalora Goicochea, J.M., Padeken, K.O., Pais, P.R., Pappalardo, L.L., Pawley, C.J., Pepe Altarelli, M., Pham, T.T.H., Pica, L., K, Resmi P., Placinta, V., Plo Casasus, M., Poli Lener, M., Polyakov, I., Pugatch, V., Puill, V., Raab, N.V., Rabadan Trejo, R.I., Rademacker, J.H., Ramos Pernas, M., Rangel, M.S., Renaudin, V., Ribatti, R., Rodrigues, A.B., Rodriguez Lopez, J.A., Rodriguez Rodriguez, E.R.R., Romanovskiy, V., Roth, J.D., Rudolph, M.S., Ruiz Fernandez, R.A., Ruiz Vidal, J., Saborido Silva, J.J., Sanchez Gras, C., Scantlebury Smead, L.G., Schune, M.H., Senghi Soares, M., Shangase, D.M., Shchemerov, I., Shevchenko, V., Shields, E.B., Shupperd, J.D., Siddi, B.G., Silva Coutinho, R., Slater, M.W., Slazyk, I., Smallwood, J.C., Smeaton, J.G., Soares Lavra, L., Sokoloff, M.D., Soler, F.J.P., Solovyev, I., Souza De Almeida, F.L., Souza De Paula, B., Spadaro Norella, E., Swallow, P.N., Tanner, A.R., Tat, M.D., Thompson, D.J.D., Thomson, K.A., Tisserand, V., Torres Machado, D., Tou, D.Y., Trilov, S.M., Unverzagt, D.J., Vázquez Sierra, C., Velthuis, J.J., Vieites Diaz, M., Vilella Figueras, E., Volle, F.C., Ward, J.A., Watson, N.K., Weber, S.G., Westhenry, B.D.C., White, D.J., Wiederhold, A.R., Wilkinson, M. K., Williams, I., Williams, M.R.J., Wilson, F.F., Wotton, S.A., Yeomans, L.E., Zhovkovska, V., Zhukov, V., Zonneveld, J.B., and LHCb Collaboration
Subjects: Particles and field, CP Violation, Nuclear and High Energy Physics, Hadron-Hadron Scattering, Settore FIS/04, PHASE, Settore FIS/01 - Fisica Sperimentale, B Physics, HEP, B Physic, LHCb, FIS/01 - FISICA SPERIMENTALE, Hadron collider, CKM Angle Gamma, Physic, LHC, CKM Angle Gamma, CP Violation, B Physics, Hadron-Hadron Scattering
Abstract: A data sample collected with the LHCb detector corresponding to an integrated luminosity of 9 fb−1 is used to measure eleven CP violation observables in B±→ Dh± decays, where h is either a kaon or a pion. The neutral D meson decay is reconstructed in the three-body final states: K±π∓π0; π+π−π0; K+K−π0 and the suppressed π±K∓π0 combination. The mode where a large CP asymmetry is expected, B±→ [π±K∓π0]DK±, is observed with a significance greater than seven standard deviations. The ratio of the partial width of this mode relative to that of the favoured mode, B±→ [K±π∓π0]DK±, is RADS(K) = (1.27 ± 0.16 ± 0.02) × 10−2. Evidence for a large CP asymmetry is also seen: AADS(K) = −0.38 ± 0.12 ± 0.02. Constraints on the CKM angle γ are calculated from the eleven reported observables.
Published: 2022

24. Vacuolar (H + )‐ <scp>ATPase</scp> subunit c is essential for the survival and systemic <scp>RNA</scp> interference response in Locusta migratoria

Author: Xuekai Shi, Xiaojian Liu, Anastasia MW Cooper, Kristopher Silver, Hans Merzendorfer, Kun Yan Zhu, and Jianzhen Zhang
Subjects: Insect Science, General Medicine, Agronomy and Crop Science
Published: 2022

25. Peer Review #2 of 'The contents of essential and toxic metals in coffee beans and soil in Dale Woreda, Sidama Regional State, Southern Ethiopia (v0.1)'

Author: MW Adem
Published: 2023

26. The geology, timing of mineralisation, and genesis of the Menninnie Dam Zn-Pb-Ag deposit, Eyre Peninsula, South Australia

Author: Roache, MW
Abstract: The Menninnie Dam Pb - Zn - Ag deposit is located on the northern Eyre Peninsula of South Australia, approximately 1-2 km south of the main mass of the Gawler Range Volcanics. The deposit has no surface expression and was located by drilling of aeromagnetic anomalies in deeply weathered, flat lying terrain. Mineralisation occurs over ‚Äöv¢v† 3 km strike and is hosted by upper amphibolite facies (‚Äöv¢v† 700¬¨‚àûC and 7 kbars) marbles and diopside-rich calc-silicate lithologies, correlated with the Katunga Dolomite and lower units of the Cook Gap Schist of the Middleback Subgroup, a subdivision of the Hutchison Group (1964- 1845 Ma.). The Katunga Dolomite is bound to the west by a shear zone(> 50 m wide) formed during the latter stages of the Kimban Orogeny (1740- 1710 Ma.). Syn-deformation granite dykes intruded into the shear zone, and, to a lesser extent, into the Katunga Dolomite and Cook Gap Schist. Late tectonic pegmatite dykes intruded into the Katunga Dolomite and lower units of the Cook Gap Schist, where they produced zones of K-feldspar- calc-silicate metasomatism. Previous researchers have incorrectly suggested that the Menninnie Dam Pb - Zn - Ag deposit is a Broken Hill-type. However, Pb - Zn - Ag mineralisation post-dates metamorphism, deformation and metasomatism and has replaced the host marble, and to a lesser extent, diopside-rich calc-silicate lithologies. On the basis of lithologic relationships, most mineralisation formed within 100 - 600m of the palaeosurface, and resulted in a central zone of stockwork and matrix to marble and calc-silicate breccias, flanked by veins. Sulphide and gangue minerals consist of a simple assemblage of pyrite, quartz, sphalerite, galena and CaMn-Mg-Fe carbonate, with accessory chalcopyrite, chlorite, adularia, sericite, fluorite, rhodonite, talc, phlogopite, dolomite, hematite and matildite. Three paragenetic stages of mineralisation are present with an early pyrite stage, followed by a sphalerite galena, and late pyrite stages. Metal abundances have a bell-shaped distribution along the length of the deposit and the highest values are associated with the zone of stockwork and breccia mineralisation. Post metamorphic, porphyritic rhyolite intruded the Hutchison Group, and interacted with (heated?) groundwater resulting in explosive fragmentation of the host rocks and formation of polymictic breccia pipes. Some of these erupted onto the palaeosurface and formed layered polymictic breccias. Rhyolite continued to intrude through polymictic breccia pipes, and resulted in formation of peperite at the margins. Some rhyolite intrusions erupted onto the palaeosurface and formed volcanic breccias and rhyolite lavas. Polymictic breccias contain clasts of paragenetically early sulphide and gangue minerals, and have an altered matrix that includes paragenetically late sulphide minerals, indicative of syn-mineralisation emplacement. U-Pb zircon dating of the rhyolite intrusions constrains the timing of mineralisation to 1594 ¬¨¬± 7 Ma. which is indistinguishable from that determined for the Hiltaba Suite granitoids and comagmatic Gawler Range Volcanics. Modelling of regional gravity and aeromagnetic data indicates the Menninnie Dam deposit lies near the north-western margin of a ‚Äöv¢v† 20 km diameter Hiltaba Suite granite that intruded to within I - 3 km of the palaeo-surface. Lead was derived from the underlying Hiltaba Suite granite and leached from Cook Gap Schist. Lead isotope ratios have a spatial distribution on a prospect scale, and the least radiogenic ratios correspond with the highest metal values and the central zone of stockwork and breccia style mineralisation, consistent with a single zone of fluid up-flow. Carbonate gangue is interpreted to have precipitated via interaction of the mineralising fluid (˜í¬•\$^{18}\$O = -2.0‚ÄövÑ‚àû; ˜í¬•\$^{13}\$C = -6.9‚ÄövÑ‚àû) in equilibrium with H\$_2\$CO\$_3\$\$_{(aq)}\$ (> 0.01 molal) and the host marbles (˜í¬•\$^{18}\$O = 15.5 to 21.09‚ÄövÑ‚àû; ˜í¬•\$^{13}\$C = -1.1 to 1.6‚ÄövÑ‚àû) between 200¬¨‚àû and 125¬¨‚àûC. Hydrous phyllosilicates associated with mineralisation have calculated fluid values of ˜í¬•\$^{18}\$O = -0.7 to -2.0‚ÄövÑ‚àû and ˜í¬•D = -43 to -48‚ÄövÑ‚àû, indicative of a mixed meteoric - magmatic origin for the mineralising fluids. Sulphide ˜í¬•\$^{34}\$S values range from -3.0 to 8.2‚ÄövÑ‚àû, with most between 4 to 6‚ÄövÑ‚àû. The lack of evidence for sulphur isotope fractionation between different sulphide minerals is consistent with non-equilibrium precipitation of sulphides from a reduced fluid, low temperature kinetic effects and / or a H\$_2\$S : metal ratio ‚Äöv¢‚Ä¢ 1. Sulphur was sourced from either the magma, the country rocks, or a combination of both. Primary fluid inclusions hosted by sphalerite and quartz have a range of trapping temperatures and salinities interpreted to have resulted from mixing of ‚Äöv¢v† 140¬¨‚àûC and =27 wt.% NaCI equivalent Na-Ca-K-Cl brine with a ‚Äöv¢v† 180¬¨‚àûC dilute chloride water. Thermodynamic modelling has shown that sufficient concentrations of Pb and Zn (> 1 ppm) can be transported together with reduced sulphur ‚Äöv†v´S = 0.002 molal) in a low temperature (150¬¨‚àûC) saline brine (‚Äöv¢v† 6 molal) to form the Menninnie Dam deposit. The physiochemical attributes of the mineralising fluid at 150¬¨‚àûC are estimated to have been log \$f\$O\$_2\$ = -46 and pH= 4.6. Dilution through mixing with heated groundwater was a possible base metal depositional mechanism but is predicted to have been less effective than the pH increase that resulted from dissolution of the host marbles. Soon after cessation of the mineralising event, the stratigraphy was mantled by a single cooling unit> 260m thick of lithic-rich ( ‚Äöv¢v† 45% and up to 20m across) welded ignimbrite (MD ignimbrite). The thickness, abundance and size of lithic clasts in the MD ignimbrite, and shallow intrusion of granite are consistent with an intracaldera setting. Following welding and cooling of the MD ignimbrite, the lower part of the MD ignimbrite and the Hutchison Group near the southern end of the Menninnie Dam deposit were partially altered to a texturally destructive quartz - chlorite - carbonate - calc-silicate assemblage by a hot, low salinity water (190- 356¬¨‚àûC and 0- 3 wt. % NaCI equiv.). Carbon, hydrogen, and oxygen isotopes are consistent with a meteoric water that had undergone partial isotopic exchange with igneous rocks. Mineral textures, whole rock geochemistry, lead and sulphur isotope data are consistent with the Menninnie Dam Pb- Zn- Ag mineralisation being partially dissolved and reprecipitated by this event, with no addition of metals or sulphur.
Published: 2023
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27. Cultural and religious themes in the life of FL Woodward

Author: Powell, MW
Abstract: FL Woodward, born in Norfolk in 1871, was inspired by the late nineteenth century fascination with Buddhism, mediated by the influential Theosophical Society, to volunteer himself for service in the Society's Buddhist educational mission to Ceylon. Woodward formed Mahinda College, Galle, into the premier Buddhist institution in southern Ceylon with considerable influence on the Buddhist Revival and the nationalist movement. Woodward's promotion, through the school, of 'Protestant Buddhism' with its emphasis on laicisation and access to the Buddhist Canon, to which he personally contributed, helped establish the shape of twentieth century Sll;lahala Buddhism. His strong promotion of national culture, and particularly use of the vernacular, also contributed to the religio-linguistic shape of twentieth century Sinhala nationalism, though not necessarily in a form with which Woodward would have approved. While Sinahala Buddhism and nationalism readily absorbed those aspects that furthered its aims, it decidedly rejected Theosophical accretions and moderation which ultimately compromised Woodward's continued presence. He retired to Tasmania to devote the last thirty three years of his life (1919-1952) to editing and translating the Pali Buddhist Canon and providing a Concordance, a work of considerable, if obscure, scholarly importance. FL Woodward has the prismatic qualities of a subaltern life that sheds light on social and religious transformations of the late nineteenth century within an imperial paradigm, and illuminates the parallel aspects of personal and cultural formation. Consequently, this is not a definitive biography but a study that appropriates Woodward's endeavours to examine a number of disparate historic and cultural themes, that would not be considered in this particular configuration but for the fact that Woodward lived them. Woodward's presence in both Ceylon and Tasmania presents as an odd tale of eccentric existence on the periphery, but far from being atypical, Woodward exhibits identifiable nineteenth century themes, albeit themes that inhabit the margins and decentred aspects of his times: -the exploration of alternative religiosity- Buddhism and Theosophy with its subsequent impact on culture and politics, was a significant sub theme of nineteenth century endeavour. -the contribution to education in Ceylon, while unusual for its Buddhist inflection was within the context of nineteenth century imperial endeavour, an obverse emulation of missionary activity. -retirement to Tasmania, far from a departure to the periphery, was part of a pattern of Anglo-Indian settlement that shaped the demography of Tasmania until the middle of the twentieth century. -the attraction to editing and translating Buddhist scriptures and commentaries, to which Woodward' s contribution was considerable, represents a extension of nineteenth century fascination with philology and textual criticism. Woodward's attraction to Buddhism and Theosophy, an alternate religiosity that appears eccentric, demonstrates a perennial religious questing which, Winnicott shows, resides within the centre of cultural formation. Said's examination of the interface with the Other on the cultural plane is aligned with Winnicott's psycho-analytic examination of the relationship of Self to Other at the personal level to offer a means of exploring the imperial experience, and in particular, the personal interest in religious ideology emanating from the Other. Woodward's experience brings together the religious encounters of the nineteenth century with the present fin de siecle, illuminating the fascination with alternate religions, cults and niche beliefs by the middle class and educated, and the persistent contrast of the rational and irrational. Woodward' s life and ideas while apparently eccentric, are, in fact, within the ordinary impulses of his time, though what the character of Woodward reveals, is that within apparently peculiar faith, resides a voice able to transcend the content of belief to touch the lives of others with thought and meaning.
Published: 2023
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28. Factors Affecting The Re-Establishment of Native Plant Species in Abandoned Pastures

Author: Appleby, MW
Subjects: Terrestrial ecology
Abstract: No description available
Published: 2023
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29. Immune system modulation in the brain injury of the metallothionein-I/II null mutant mouse

Author: Pankhurst, MW
Abstract: Metallothionein-I/II (MT-I/II) is a 6-7 kDa, cysteine rich, zinc and copper binding protein. MT-I/II null mutant (\$^{‚Äöv†v¿/‚Äöv†v¿}\$) mice have an altered response to brain injury. Therefore, MT-I/II has been proposed to be a protective protein after brain injury but the mechanism by which it confers protection remains elusive. There is a possibility that MT-I/II has protective actions within the injured brain but MT-I/II also has the capacity to modulate the immune system which plays a role in the progression of brain injury. The aim of this thesis is to investigate the differences in the progression of brain injury between wild type and MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice with particular emphasis on the action of MT-I/II in organs peripheral to the central nervous system after brain injury. Using a cryolesion brain injury model, neuron death in MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice was prolonged at later stages of the brain injury (7 days post-injury) meanwhile it had ceased in wild type mice. In conjunction with this occurrence, the numbers of T cells infiltrating the injury site were significantly higher in MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice at 7 days post-injury. Chemokine mRNA synthesis was analysed to determine if MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice had altered chemotactic signals that may affect the rate of T cell infiltration but differences were rarely observed when compared to wild type mice. In MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice, circulating leukocytes showed no differences to wild type mice in the relative ratios of lymphocytes, neutrophils, monocytes or T cells. However, the absolute white blood cell count was significantly higher in the blood of MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice, but only at 7 days post-injury. MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice were also found to have lower levels of the marker of alternatively activated macrophages, Ym1, than wild type mice, both in macrophages in the brain and in monocytes in the blood after brain injury. Therefore, there appear to be several immune system differences between MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice and wild type mice after brain injury. To further investigate the role of MT-I/II after brain injury, MT-I and MT-II mRNA levels were quantified by reverse transcriptase PCR. An enzyme-linked immunoassay (ELISA) was developed to measure MT-I/II protein levels in brain and liver after brain injury. Both MT-I and MT-II mRNA levels increase at 1 day post-injury in brain and liver and are decreased by 7 days post-injury. MT-I/II protein in brain was highest at 1 day post-injury but in the liver was maximally expressed at 7 days post injury. This increase in hepatic MT-I/II protein resulted in a higher hepatic zinc content in wild type mice compared to MT-I/II\$^{‚Äöv†v¿/‚Äöv†v¿}\$ mice. Therefore these results suggest that brain injury induces a hepatic MT-I/II response which may be responsible for modulation of the essential trace metal, zinc after brain injury.
Published: 2023
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30. Sedimentology and diagenesis of Upper Devonian carbonates, Canning Basin, Western Australia

Author: Wallace, MW
Abstract: Two Upper Devonian carbonate sequences in the Canning Basin were investigated: a) an outcropping sequence in the Geikie Gorge region on the Lennard Shelf; and b) a subsurface sequence on the Barbwire Terrace. The outcropping Frasnian-Famennian carbonates of the Geikie Gorge region form part of the Devonian \Great Barrier Reef\" of the Canning Basin and consist of a series of platforms and atolls which fringe the basin margin. The platforms have steep reef-fringed margins and the framework lithologies consist predominantly of cyanobacterial framestones. A widespread deeper water stromatolite unit stromatolite unit straddles the Frasnian-Famennian boundary and appears to represent a major halt in reef growth. Stromatactis structures are most common in the reefal-slope subfacies and appear to have formed by soft-body collapse in combination with later internal erosion and sedimentation. The carbonates of the Geikie Gorge region have suffered a long and complex diagenetic history which began in Devonian sea water with extensive marine cementation of platform-margin lithologies. Devonian - Lower Carboniferous burial diagenesis was the most important episode of diagenesis as almost all primary porosity was occluded by calcite cementation (non-luminescent to bright-luminescent to dullluminescent) during this interval. Dolomitization and consequent secondary porosity development also occurred during this interval. Some karstification and calcite cementation took place during Late Carboniferous subaerial exposure. Minor calcite cementation occurred during Permian - Cenozoic burial. Karstification dedolomitization and calcite recrystallization took place during Cenozoic meteoric diagenesis. Recrystallized sparry calcites commonly display cathodoluminescent crystal growth zonations which mimic cementation fabrics. The Barbwire Terrace carbonates consist predominantly of low-energy peritidal and shallow-subtidal lithologies in which most of the clay-free lithologies have been thoroughly dolomitized. The peritidal lithologies resemble those found in the modem arid tidal flats of the Persian Gulf. Cyclic sequences are not well developed in the peritidal lithologies. No true reef-framework lithologies were recognized in the sequence. The dominant synsedimentary diagenetic process was supratidal dolomitization and associated anhydrite precipitation. The `˜í¬•^18O` value for Devonian marine dolomite `{˜í¬•^18O = ~2 ‚ÄövÑ‚àû (PDB)}` was estimated by assuming that the lowest `˜í¬•^18O` values for the supratidal dolomite represent replacement in marine waters. The most important diagenetic process affecting the carbonates was regional dolomitization and this occurred during Devonian - Lower Carboniferous burial diagenesis. Regional dolomitization was not restricted to the peritidal lithologies and thick sequences (up to 600 m) of dolomite with no primary calcite are common. The regionru dolomites have lower `˜í¬•^18O`values than the supratidal synsedimentary dolomite and saddle dolomite cements are common suggesting elevated temperatures of precipitation. Karstification and calcite cementation took place in the dolomites during Late Carboniferous subaerial exposure. Poilcilitic calcite cements were precipitated during Permian - Cenozoic burial diagenesis."
Published: 2023
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31. sj-docx-1-eso-10.1177_23969873231182492 – Supplemental material for Diagnostic value of carotid intima-media thickness and clinical risk scores in determining etiology of ischemic stroke

Author: Sievering, Esther MW, Grosshennig, Anika, Kottas, Martina, Ernst, Johanna, Ringlstetter, Rieke, Koch, Armin, Weissenborn, Karin, and Grosse, Gerrit M
Subjects: FOS: Clinical medicine, Cardiology, Medicine, 110904 Neurology and Neuromuscular Diseases
Abstract: Supplemental material, sj-docx-1-eso-10.1177_23969873231182492 for Diagnostic value of carotid intima-media thickness and clinical risk scores in determining etiology of ischemic stroke by Esther MW Sievering, Anika Grosshennig, Martina Kottas, Johanna Ernst, Rieke Ringlstetter, Armin Koch, Karin Weissenborn and Gerrit M Grosse in European Stroke Journal
Published: 2023
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32. Geology and genesis of the Lewis Ponds carbonate and volcanic-hosted massive sulfide deposits, New South Wales, Australia

Author: Agnew, MW
Abstract: The Lewis Ponds carbonate and volcanic-hosted Zn-Pb-Cu-Ag-Au-rich massive sulfide deposits are located near the western margin of the Hill End Trough, in the eastern Lachlan Fold Belt of New South Wales. Two stratabound massive sulfide zones, Main and Toms occur in a tightly folded Late Silurian marine succession of volcaniclastic sandstone, polymictic breccia, limestone-clast breccia, siltstone and mudstone. They have a combined indicated resource of 5.7 Mt, grading 3.5% Zn, 2.0% Pb, 0.19% Cu, 97 g/t Ag and 1.9 g/t Au. Main zone occurs within a thick unit of poorly-sorted mixed provenance breccia, limestone-clast breccia and pebbly-granular sandstone, whereas Toms zone is hosted by siltstone. The sedimentary rocks unconformably overlie a thick succession of quartz-plagioclase phyric dacite and strongly foliated, chlorite-sericite-altered dacite. Variably recrystallised fossiliferous limestone occurs throughout the Lewis Ponds host sequence in thick, tabular units of poorly-sorted breccia and fault-bound lenses of megabreccia. Limestone clasts vary in size from small pebbles to 90 m boulders. The mixed provenance breccia, limestone-clast breccia and sandstone were deposited in a moderately deep water, below wave-base slope environment, around the margins of a high-level intrusive dacite centre. Detrital volcanic and sedimentary components were derived from multiple source areas within the basin and in the adjacent hinterland. The massive sulfide lenses occur along the eastern limb of a regional-scale D I anticline. The adjacent syncline has been partly truncated by a 200-250 m wide, NNW-trending high strain zone termed the Lewis Ponds fault. Syn-tectonic quartz ¬¨¬± sulfide veins and steeply dipping, anastomosing shear zones surround the Toms massive sulfide lens. The variably folded and boudinaged quartz veins resulted from periodic brittle shear failure and extension during and after the D I deformation. Pinch-and-swell structures, boudins, catalcastic breccia and kink folds occur in the massive sulfide. Main zone, located west of the fault is significantly less deformed than Toms zone. However, reversals in stratigraphic facing and vergence indicate that tight parasitic folds occur in the Main zone host sequence. Mineralisation at Lewis Ponds probably pre-dated shearing along the Lewis Ponds fault. An asymmetric, semiconformable Mg-Fe-Ca-Ba-rich hydrothermal alteration envelope surrounds the massive sulfide lenses. Mg-chlorite occurs at the top the footwall volcanic succession south of Main zone and grades outwards into a weak pervasive sericite-quartz ¬¨¬± Fe-Mg-chlorite assemblage. The compositions of recrystallised phyllosilicates vary systematically with whole rock geochemistry, alteration intensity and proximity to the Toms massive sulfide lens. Hydrothermal alteration of dacite in the Toms zone footwall involved MgO, Fe203, K2 0 and Ba enrichment and Na2O, CaO and Sr depletion. The addition or removal of Si02 contributed to net gains of 0-75 g/100g in dacite C and net losses of 0-50 g/100g in dacite A, except where MgO and Fe 203 gains offset the loss of Si02. In contrast, weak sericite-chlorite-calcite alteration of coherent dacite in the Main zone footwall led to net losses of 10-40 g/100g. Conformable, texturally destructive alteration assemblages associated with the two mineralised zones include dolomite-chlorite-talc, chlorite-pyrite, quartz-dolomite-chlorite and quartz-sericite ¬¨¬± hyalophane. Dolomite, Mg-chlorite, talc, phlogopite, calcite, quartz and sulfides have overprinted the clasts and matrix in the breccia and sandstone units in Main zone. Relict crinoid fossils are preserved in even the most intensely altered rocks, where dolomite, chlorite and talc have replaced the original calcite. Irregular honeycomb vuggy and botryoidal sulfide-dolomite textures in the breccia and sandstone units indicate dissolution and precipitation of dolomite during mineralisation. Dolomite associated with the massive sulfide lenses is characterised by low [delta to the power 18]vsmow (6 to 16%o) and [delta to the power I3Cvpdb (-II to 0%o) values relative to the regional fossiliferous limestone. Fluid inclusion and stable isotope data indicate that the dolomite precipitated from a low temperature (166-232¬¨‚àûC for 1 000 m water depth), weakly saline (1.4 to 7.7 eqiv wt % NaCl) fluid, possibly depleted in [omicron] and C isotopes ([delta to the power 18 omicron] = -2.5 to 0.3%o, [delta to the power 13]C = -14 to -4%o). The dolomite probably formed during diagenesis and hydrothermal alteration, by fluid-rock interactions between evolved seawater at 150-250¬¨‚àûC and the limestone-bearing host sediment, and/or mixing between evolved seawater at 350¬¨‚àûC and a seawater-dominant pore fluid at 100¬¨‚àûC. The massive sulfide lenses consist of pyrite, sphalerite and galena, with subordinate tetrahedrite, chalcopyrite, arsenopyrite, pyrrhotite, stannite, pyrargyrite and electrum. Paragenetically early framboidal, dendritic, reticulate, botryoidal and spongy Fe-sulfide aggregates and bladed pyrrhotite pseudomorphs of sulfate occur throughout the breccia and sandstone beds that host Main zone, but are rarely preserved in the coarse grained, annealed massive sulfide in Toms zone. Pre-tectonic carbonate-chalcopyrite-pyrite veins in the footwall volcanic succession, immediately south of Toms zone may represent a stringer zone displaced from the Toms massive sulfide lens. The stringer veins also contain native bismuth, sphalerite and Se-Bi-Ag-rich galena. Sulfur isotope values in the massive sulfide ([delta to the power 34]S = 1.7-5.0%0) and footwall stringer veins (6345= 3.9-7.4%0), indicate that the hydrothermal fluid contained a homogenous mixture of magmatic S, derived from the host volcanics rocks and reduced seawater sulfate. The lower average [delta to the power 34]34S values in the massive sulfide lenses may have resulted from a component of partially reduced seawater sulfate or biogenic S, leached out of the host sediment. Textural, geochemical and isotopic data indicate that the Main zone massive sulfide lenses formed by lateral fluid flow and sub-sea floor replacement of the poorly-sorted, carbonate-bearing breccia and sandstone beds. Low temperature dolomitisation of the carbonate-bearing sediment during diagenesis created secondary pore spaces and provided a reactive host for fluid-rock interactions. Base metal sulfides, chlorite, dolomite, calcite, quartz and talc filled pore spaces throughout the carbonate-altered breccia and sandstone units. Toms zone probably formed in fine-grained sediment at or near the sea floor, above a zone of focused up-flowing hydrothermal fluids. Pyrite, pyrrhotite, sphalerite, galena, tetrahedrite and electrum precipitated from a relatively low temperature 150-250¬¨‚àûC, reduced hydrothermal fluid. Paragenetically early dendritic, reticulate and spongy Fe-sulfide aggregates in the Main zone host sequence formed by rapid mixing between the hydrothermal fluid and cooler pore fluids in the matrix of the breccia and sandstone. Base metal sulfide deposition in Main zone probably resulted from fluid mixing, dissolution of dolomite and increased fluid pH. Galena, sphalerite and chalcopyrite overprinted the primitive Fe-sulfide textures. As the hydrothermal system intensified, a high temperature >280¬¨‚àûC, strongly reduced fluid carrying Sn, Cu, Se and Bi was sourced from deep within the footwall volcanic succession. Carbonate-chalcopyrite-pyrite stringer veins and dolomite-chalcopyrite-pyrite-stannite veins formed in the Footwall Copper zone and Toms zone Central lens respectively. Chalcopyrite partly replaced the Zn-Pb-rich massive sulfide in Main zone. During the DI deformation, fracture-controlled fluids remobilised sulfides into syn-tectonic, quartz and carbonate veins within the Lewis Ponds fault zone and adjacent footwall volcanic succession, resulting in extensive Cu, Au and Zn anomalies. Massive sulfide remobilisation may have occurred over tens to hundreds of metres. Talc, quartz-sericite, chlorite and Fe-Mg-Mn-carbonate assemblages overprinted the dolomite, chlorite and sericite-altered rocks in the Toms zone host sequence. Lewis Ponds is an unusual stratabound, carbonate and volcanic-hosted massive sulfide deposit. The intimate spatial association between fossiliferous limestone, hydrothermal carbonate and base metal sulfides at Lewis Ponds provides a basis for new exploration targets in Siluro-Devonian marine successions elsewhere in New South Wales.
Published: 2023
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33. Memorist evocation : painting as a mnemonic device

Author: Nay, MW
Abstract: By investigating the connections between the real, remembered and imagined, this research project set out as an inquiry into the capacity of painting to function as a mnemonic device. People who use such devices can be referred to as memorists‚ÄövÑvp (Reber, Allen & Reber 2009). Through process-based drawing, collage and painting, I placed objects, imbued with traumatic family histories, into compositions that were visual attempts at remembering spaces of my childhood. My intention was to test relationships that exist between drawing and collage and how each of these processes could bring to painting the experience of remembering. Painting, I concluded, was an articulate practice that benefited from the disjointed and fragmentary nature of collage as a preparatory process. The paintings draw on remembered events with the backdrop of the 1960s and 1970s of my childhood. Inherited objects from this time provide evidence of my ancestral trauma of penury, diaspora and war. In my hand these vestige objects have the literal weight of their primary function and the metaphoric weight of memories. Vestige describes a disparate group of inherited ancestral objects including a bayonet from the Great War, a family bible, and whimsies such as a ceramic figurine. The paintings are about these real objects and their histories painted on canvas from life or photographs, coalescing in contextual spaces based on uncertain childhood memories. The project was supported by research into theories of memory, objects and landscape. Each contribution, philosophical or clinical, co-acted for strategies and methodologies in making. Psychoanalytic theories (of van der Kolk, Laplanche and Pontalis) provided working definitions of memory-recall that aligned with painting strategies in the studio. The work of Maurice Halbwachs offered insights into existential questions relating to physical objects in daily contact and notions of permanence and stability. Ian Farr theorised on the role of landscape in the consciousness of childhood. Jill Bennett, in her work Empathic Vision, discusses the use of fiction and fantasy in art that endeavours to visually register experience of traumatic memory. Artworks discussed in the Context chapter, 2 are significant because they exemplify the evocative potency of trauma, memory, banal objects and interior spaces in collage and painting. The work explores various interpretive modes of painting that challenge ways of perceiving the encounters between subjective realities and the above topics. Examination of work by Albert Tucker and Imants Tillers provided a perspective on trauma and diaspora. Paintings by Matthias Weischer and Dexter Dalwood are used to discuss the relationship between pictorial 'interior space' and memory. Historical perspectives on still life and collage in the work of Picasso and Braque are contrasted with a contemporary collaging of 'tabletop' space in the work of James Lynch. In conclusion I found that vestige objects have the ability to draw something out of the painter, more than could have been understood at the beginning of the project. An intimate engagement was established with the objects. They were near enough to be touched and constantly scrutinised. This intimacy allowed me to reflect on their original intended functions: killing, advertising and story-telling, all being different from their banal utilitarian, domestic functions as remembered from childhood. The paintings problematize the relationships between real objects, their remembered banality and their representation in paint. My thesis demonstrates that, with the techniques I have employed, I can bring these things together. Paintings have considerable coherency (structurally) to offer a plausible pictorial account of how one might visualise and make sense of the snippets of childhood memory that have such a significant role to play in psychological and social formation.
Published: 2023
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34. A comparison of self-reported risk and protective factors and the death implicit association test in the prediction of future suicide attempts in adolescent emergency department patients

Author: Brent, DA, Grupp-Phelan, J, O'Shea, BA, Patel, SJ, Mahabee-Gittens, EM, Rogers, A, Duffy, SJ, Shenoi, RP, Chernick, LS, Casper, TC, Webb, MW, Nock, MK, King, CA, and for Pediatric Emergency Care Applied Research Network (PECARN)
Subjects: Suicide Prevention, Adolescent, emergency department, Adolescents, Risk Assessment, Emergency Care, Suicidal Ideation, Hospital, Risk Factors, Clinical Research, Behavioral and Social Science, Humans, Psychology, suicide attempts, Child, implicit association test, Attempted, Pediatric, Psychiatry, Emergency Service, Prevention, Neurosciences, prediction, Protective Factors, self-report, Suicide, for Pediatric Emergency Care Applied Research Network, Mental Health, Public Health and Health Services, Self Report
Abstract: BackgroundConcerns have been raised about the utility of self-report assessments in predicting future suicide attempts. Clinicians in pediatric emergency departments (EDs) often are required to assess suicidal risk. The Death Implicit Association Test (IAT) is an alternative to self-report assessment of suicidal risk that may have utility in ED settings.MethodsA total of 1679 adolescents recruited from 13 pediatric emergency rooms in the Pediatric Emergency Care Applied Research Network were assessed using a self-report survey of risk and protective factors for a suicide attempt, and the IAT, and then followed up 3 months later to determine if an attempt had occurred. The accuracy of prediction was compared between self-reports and the IAT using the area under the curve (AUC) with respect to receiver operator characteristics.ResultsA few self-report variables, namely, current and past suicide ideation, past suicidal behavior, total negative life events, and school or social connectedness, predicted an attempt at 3 months with an AUC of 0.87 [95% confidence interval (CI), 0.84-0.90] in the entire sample, and AUC = 0.91, (95% CI 0.85-0.95) for those who presented without reported suicidal ideation. The IAT did not add significantly to the predictive power of selected self-report variables. The IAT alone was modestly predictive of 3-month attempts in the overall sample ((AUC = 0.59, 95% CI 0.52-0.65) and was a better predictor in patients who were non-suicidal at baseline (AUC = 0.67, 95% CI 0.55-0.79).ConclusionsIn pediatric EDs, a small set of self-reported items predicted suicide attempts within 3 months more accurately than did the IAT.
Published: 2023

35. Associations between Participant Characteristics and Participant Feedback about an Unsupervised Online Cognitive Assessment in a Research Registry

Author: Ashford, MT, Eichenbaum, J, Jin, C, Neuhaus, J, Aaronson, A, Ulbricht, A, Camacho, MR, Fockler, J, Flenniken, D, Truran, D, Mackin, RS, Maruff, P, Weiner, MW, and Nosheny, RL
Subjects: education, Brain, feedback, General Medicine, Neuropsychological Tests, Basic Behavioral and Social Science, Brain health registry, Quality Education, Cogstate Brief Battery, Cognition, Clinical Research, Behavioral and Social Science, Humans, Female, Mental health, Registries, race
Abstract: BackgroundThis study aims to understand whether and how participant characteristics (age, gender, education, ethnocultural identity) are related to their feedback about taking a remote, unsupervised, online cognitive assessment.MethodsThe Brain Health Registry is a public online registry which includes cognitive assessments. Multivariable ordinal regressions assessed associations between participant characteristics and feedback responses of older (55+) participants (N=11,553) regarding their Cogstate Brief Battery assessment experience.ResultsHigher age, secondary education or less, Latino identity, and female gender were associated with a poorer assessment experience; higher age and a non-White identity were associated with experiencing the assessment instructions as less clear; and higher age, non-White identity, and secondary education or less were associated with rating additional human support with the assessment as more useful.DiscussionOur findings highlight the importance of improving the design and instructions of unsupervised, remote, online cognitive assessments to better suit the needs of diverse communities.
Published: 2023

36. Thriving in transition : the personal characteristics and processes of thriving in young males in periods of geographic dislocation

Author: Harris, MW
Abstract: This study examined the personal characteristics and processes of thriving in a group of young men during a geographically dislocating transition. The concept of thriving broadened the traditional vulnerability and coping focus of transition research, to one that incorporated positive learning and growth. The challenging circumstances surrounding geographic dislocation provided the context for these characteristics and processes to be examined and explained. The study was conducted with 24 young male, elite athletes drawn from the Australian Football League who were required to relocate to take up their player contracts. A partially mixed, sequential design was employed, firstly to identify the features of the participant group. Despite their homogeneity on a range of instruments, the outcome variations were not adequately explained. Subsequently, the particular characteristics and processes that contributed to thriving were examined. From the results, a comprehensive analysis of the experience of the geographically, dislocating transition identified a principle group of 16 characteristics (concepts) and associated processes. Based on variations in these identified concepts, the study's participants clustered in one of three groups (categories): those who were thriving, surviving or languishing in regard to the challenge of the geographically dislocating transition. Thriving was further examined in relation to a theoretical framework of transition as a cyclical process. This was explained as a dynamic exchange across stages of transition, rather than as a standard linear model. While the transition was recursive, the stages were disjunctive and at the same time interconnected. Thriving explained by this model required the resolution of tasks associated with the concepts at each stage. For each of the categories the concepts were the same however the resolution of the associated tasks was more problematic. The recursive process of learning gave the thriving participants a significant advantage. They had a positive trajectory on the thriving transition cycle and their ability to progress was enhanced by the satisfactory resolution of issues at each stage of the challenge. Those whose tasks were poorly resolved or unresolved were less able to thrive as the transition unfolded. This study provided new insights into the characteristics and processes of thriving in a geographically dislocating transition. Thriving was observed as a cyclic, staged process where the trajectories of passage, and adjustment strategies, exerted a significant influence on the outcomes. To advance the learnings from this research and to broaden the application of possible interventions, the direction of future research should extend the methodology to other groups in transition, and to a wider range of transition challenges.
Published: 2023
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37. Characterization of a novel beta-barrel protein (AtOM47) from the mitochondrial outer membrane of Arabidopsis thaliana

Author: Li, L, Kubiszewski-Jakubiak, S, Radomiljac, J, Wang, Yan, Law, SR, Keech, O, Narsai, Reena, Berkowitz, Oliver, Duncan, O, Murcha, MW, and Whelan, James
Subjects: Uncategorized
Abstract: In plant cells, mitochondria are major providers of energy and building blocks for growth and development as well as abiotic and biotic stress responses. They are encircled by two lipid membranes containing proteins that control mitochondrial function through the import of macromolecules and metabolites. Characterization of a novel β-barrel protein, OUTER MEMBRANE PROTEIN 47 (OM47), unique to the green lineage and related to the voltage-dependent anion channel (VDAC) protein family, showed that OM47 can complement a VDAC mutant in yeast. Mutation of OM47 in Arabidopsis thaliana by T-DNA insertion had no effect on the import of proteins, such as the β-barrel proteins translocase of the outer membrane 40 (TOM40) or sorting and assembly machinery 50 (SAM50), into mitochondria. Molecular and physiological analyses revealed a delay in chlorophyll breakdown, higher levels of starch, and a delay in the induction of senescence marker genes in the mutant lines. While there was a reduction of >90% in OM47 protein in mitochondria isolated from 3-week-old om47 mutants, in mitochondria isolated from 8-week-old plants OM47 levels were similar to that of the wild type. This recovery was achieved by an up-regulation of OM47 transcript abundance in the mutants. Combined, these results highlight a role in leaf senescence for this plant-specific β-barrel protein, probably mediating the recovery and recycling of chloroplast breakdown products by transporting metabolic intermediates into and out of mitochondria.
Published: 2023
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38. The geological evolution of the Norseman Area, Western Australia

Author: Hope, MW
Abstract: Norseman lies 200 km south of Kalgoorlie within the most southern part of the late Archaean Eastern Goldfields Province of Western Australia. This study resolves the stratigraphy and structure of the upper Norseman Terrane and proposes tectonic models to explain the formation of the terrane and differences with the adjacent Kalgoorlie Terrane. Problems with the current understanding of the lower stratigraphy of the Norseman Terrane were identified, but not fully resolved. Geological mapping at 1:2500-scale of the upper part of the Norseman Terrane at the Polar Bear Peninsula; revealed five Archaean facies associations: ‚Äö Mafic volcanic rocks and dolerite intrusives; ‚Äö Ultramafic rocks; ‚Äö Mafic conglomerate and sandstone; ‚Äö Fine-grained sedimentary units, dominantly pyritic black shales and thin-bedded, siltstone-shale turbidites; and ‚Äö Rhyolite lavas and both in situ and resedimented breccias. The stratigraphy and geometry of the map patterns, when combined with age dating from the Eastern Goldfields, suggests that basalts overlying the Norseman komatiite are a thrust repetition of basalts from below the komatiite. This hypothesis is supported by trace element geochemistry that found all basalts above and below the komatiite have similar tholeiitic composition. They do not possess the distinctive siliceous high magnesium chemistry of the basalts that overlie the komatiite at Kambalda. Basalts from the lower Penneshaw Formation at the base of the Norseman stratigraphic succession also have a tholeiitic composition and are interpreted as another thrust repetition of the mafic greenstone package. The uppermost stratigraphy preserved within the Norseman Terrane is rhyolite at Polar Bear. Facies analysis of rhyolite and breccias indicates the rock units represent a submarine lava dome that was emplaced upon unconsolidated black shale, generating peperite breccias. At the margins of the dome, where it pinches out of the stratigraphy, the equivalent strata are rhyolite-sediment breccias and sandstone. These represent the lower sections of gravelly and sandy high-density turbidites resulting from gravitational collapse of sections of the dome. Underlying fine-grained sediments were incorporated as rip-up clasts. Two evolved felsic rock suites are distinguished within the Norseman Terrane. The first suite (Polar Bear rhyolite lava, intrusive Ajax rhyolite porphyry, Harlequin rhyolite porphyry dyke and the Dundas Granite) is interpreted to have been deiived from fusion of a siliceous crustal basement source. The second suite (intrusive Polar Bear quartz porphyry and Harlequin granodiorite) is interpreted to have originated as magma with a high-Al Trondhjemite-Tonalite-Dacite (TTD) chemistry. Low pressure feldspar fractionation was a key process in the subsequent development of the members in both suites. In the adjacent Coolgardie Domain of the Kalgoorlie Terrane, at an equivalent upper stratigraphic level, dacitic conglomerate, sandstone and siltstone of the Black Flag Beds (BFB) are present. These rocks represent erosional products of emergent volcanic centres, which were subsequently deposited as high density turbidites within the Kalgoorlie Basin, a depression that previous studies indicate is a rift basin developed under an extensional tectonic regime. These dacitic epiclastic rocks and other intrusive felsic porphyries have distinctive high-Al TTD suite chemistry, thought to form by melting of young, hot, subducted oceanic crust. There is no geochemical evidence within these dacites and other felsic intrusives, of low pressure feldspar fractionation. The stratigraphic and geochemical differences between the felsic rocks within the Kalgoorlie Terrane and the Norseman Terrane are interpreted to be the result of differing degrees of extension. The Kalgoorlie Terrane formed the central axis of an island arc. The arc rifted, forming the Kalgoorlie Basin, which was filled with BFB epiclastic volcanics and sediments. The extension assisted the ready passage to the surface, of magmas generated deep in the subduction zone. The Norseman area was marginal to the Kalgoorlie Basin rind did not undergo substantial extension. Efficient magma conduits were not developed sb that subduction zone magmas became trapped in crustal magma chambers and underwent feldspar fractionation. Intrusion and underplating of subduction zone magmas caused melting of felsic basement forming the rhyolites. Closure of the Kalgoorlie Basin occurred during N-S directed compression, suggested to have resulted from continental collision at the subduction zone. This compression caused large scale thrusts that throw the basaltic greenstories over the komatite in the Norseman Terrane. It also pushed the entire Norseman area in the north, developing it as an allochthonous fault-bounded terrane, which split the former Kalgoorlie basin and caused it to wrap around the Norseman Terrane to the east arid west.
Published: 2023
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39. Studies on the nature of the pathogenicity of soil-borne Cylindrocarpon species

Author: Sweetingham, MW
Abstract: A study was made of the association of Cylindrocarpon species with the below-ground portions of a range of plants in Tasmania, and of the pathogenic effects of members of the genus. A selective medium was developed to enhance the recovery of Cylindrocarpon species from soil and plant tissue. Several species were isolated from the root surfaces of a range of apparently healthy woody and herbaceous plants. Cylindrocarpon species were also isolated from the discoloured vascular tissue in the basal stem portion of several diseased woody plant species. C. destructans was the most frequently isolated species, but C. didymum, C. obtusisporum, C. tenue, C. theobromicola, C. candidum and an undescribed species were also recorded. The cultural characteristics and morphology of the isolates were described. Most of the Cylindrocarpon isolates produced either the metabolite brefeldin A or radicicol when cultured on Czapek Dox medium. The non host-specific phytotoxicity of brefeldin A was confirmed and the spectrum of its antifungal activity was also examined. A brefeldin A producing strain of C. destructans was consistently isolated from the discoloured wood in the base of the trunks of mature grapevines suffering from a dieback disease. The xylem vessels and functional phloem became blocked with tyloses and gum and fungal hyphae were visible in the ray cells of the diseased tissue. No other potential pathogens were isolated from the diseased tissue. Field observations suggested that the waterlogging of the trunks at groundlevel was necessary for the disease to develop. A waterlogging stress was required for the fungus to reproduce the characteristic disease symptoms on inoculated six-month-old vine cuttings. However, brefeldin A was not detected in naturally diseased grapevine tissue and could not be demonstrated to have a role in this disorder. Certain brefeldin A producing strains of Cylindrocarpon were capable of parasitizing the root cortex of radiata pine seedlings under steriIe conditions, causing a suppression in root growth. Radiata pine seed germinated in the presence of brefeldin A similarly produced stunted roots. Likewise, the growth of strawberry plants was significantly reduced, in the absence of other disease symptoms, when grown in sterilised soil amended with a brefeldin A producing isolate of C. destructans. This effect was reproduced by growing strawberry plants in soil amended with brefeldin A. Brefeldin A was absorbed by the strawberry roots and translocated into the shoots. All the CyIindrocarpon isolates were shown to produce a spectrum of pectin degrading isoenzymes when cultured on appropriate media. Inoculation experiments showed several Cylindrocarpon species were capable of producing \soft rot\" type lesions on carrot roots. Several species could also infect the hypocotyl of radiata pine seedlings in sterile media causing post emergence damping-off. Pectin lyase enzymes were detected in the lesions from both carrot roots and radiate pine hypocotyls and may be responsible for the tissue maceration. However virulence of the isolates was not related to pectin lyase production in vitro."
Published: 2023
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40. A Neuromarketing Framework Based on Human Computer Interaction (HCI) and Machine Learning for the Classification of Customers' Emotional States

Author: MW Geda, Yuk Ming Tang, and CKM Lee
Subjects: History, Polymers and Plastics, Business and International Management, Industrial and Manufacturing Engineering
Published: 2023

41. Expression of the miR‐17~92a cluster of microRNAs by regulatory T cells controls blood glucose homeostasis

Author: Yangnan Zhang, Jarrod P Skinner, and Mark MW Chong
Subjects: Blood Glucose, Male, Mice, MicroRNAs, Immunology, Animals, Homeostasis, Immunology and Allergy, Female, Cell Biology, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory
Abstract: Regulatory T cells (Tregs) are a specialized immune cell type that play important roles in regulating immune responses. However, those found in adipose tissue, particularly visceral adipose tissue (VAT), have also been shown to exert metabolic regulatory functions. This study investigated the requirement of the miR-17~92a cluster of microRNAs in VAT Tregs and the impact on blood glucose. This cluster of microRNAs is one that we previously showed to be important for the fitness of Tregs found in secondary lymphoid organs. It was found that male mice with Treg-specific miR-17~92a deficiency are resistant to impaired glucose tolerance induced by a high-fat diet. However, high-fat feeding still impaired glucose tolerance in female mice with Treg-specific miR-17~92a deficiency. There was an increase in KLRG1
Published: 2021

42. US Public Opinion as to Whether 'The Pandemic is Over,' September to October 2022

Author: Mark É Czeisler, Matthew D Weaver, Rashon I Lane, Shantha MW Rajaratnam, Mark E Howard, and Charles A Czeisler
Abstract: ImportanceUS public health guidance has increasingly shifted responsibility for actions to minimize ongoing impacts of COVID-19 onto individuals. During September to October 2022, the World Health Organization continued to characterize COVID-19 as a pandemic. Yet, public perceptions of the pandemic status of COVID-19 and its associations with COVID-19-related behaviors were unknown.ObjectiveTo assess US public opinion on the characterization of COVID-19 as a pandemic.Design, Setting, and ParticipantsThe COVID-19 Outbreak Public Evaluation (COPE) Initiative internet-based surveys, administered to 4985 US adults during September to October 2022. Demographic quota sampling and survey weighting were employed to improve sample representativeness of the US population by age, sex, and combined race and ethnicity.ExposuresThe COVID-19 pandemic.Main Outcomes and MeasuresResponse to the statement, “The pandemic is over.”‘ Response options included Strongly agree, Somewhat agree, Neutral, Somewhat disagree, and Strongly disagree.ResultsOverall, 5015 US adults completed The COPE Initiative surveys (response rate, 56.2%), and 4985 (99.4%) provided complete information for all analyzed variables and were included in this analysis. Only 1657 (33.2%) respondents agreed with the statement “the pandemic is over,” while 2141 (43.0%) disagreed and the remaining 1187 (23.8%) were neutral about the statement. Agreement that the pandemic was over was most strongly associated with having received fewer COVID-19 vaccines, lesser concern about SARS-CoV-2 variant viruses, and less frequent engagement in COVID- 19 preventive behaviors, such as mask usage in public spaces, as well as increasingly conservative political ideology, roles as unpaid caregivers of both children and adults, younger age, male sex, and significant disabilities.Conclusions and RelevanceAs of September to October 2022, US public opinion was mixed on the characterization of COVID-19 as a pandemic. Belief the pandemic was over was associated with less frequent engagement in COVID-19 preventive\behaviors, highlighting the important role of public health communication. Demographic groups to prioritize tailored public health messaging about the pandemic status were identified. Continued assessment of public perceptions about the state of the pandemic is warranted entering Year 4 of the COVID-19 pandemic.Key PointsQuestionAs of September to October 2022, what was US public opinion as to whether COVID-19 remained a pandemic?FindingsIn this demographically representative survey study of 4985 US adults, only 1 in 3 respondents agreed with the statement “the pandemic is over;” 43% of adults disagreed. Agreement that the pandemic was over was associated with less engagement in COVID-19 preventive behaviors and more political conservatism.MeaningAs of September to October 2022, US public opinion was divided regarding the status of COVID-19 as a pandemic and is associated with COVID-19-related behaviors, underscoring important public health and policy implications of this designation.
Published: 2022

43. ‘Where angels fear to tread’—Reflections on the role of an actuary as expert witness in the Land Claims Court

Author: Lowther, MW
Subjects: Land reform, land restitution, compensation, professionalism, General Medicine
Abstract: In this paper, the author reflects on his experiences of giving expert actuarial witness in the Land Claims Court regarding the calculation of financial compensation as an alternative to the restoration of dispossessed land. As no specific formula for compensation has been legislated in South Africa’s land reform programme, relevant case histories are examined in which the common law has been developed. The technical, ethical and professional inputs which an actuary can provide are reviewed. The author concludes that actuaries are well suited to assist the Land Claims Court to resolve the potentially large number of claims, and that this will be in the public interest.
Published: 2022

44. Quality of life of patients with functional bowel disorders

Author: yosra zaimi, Ghassen Trabelsi, Maha Shimi, Dougaz MW, shema ayadi, Emna Bel Hadj Mabrouk, and Leila Mouelhi
Abstract: Background and objectives : Functional bowel disorders are the most common digestive disorders. Although not life-threatening, they have a repercussion on the quality of life (QOL) of patients. The objective of our study was to measure the QOL of patients followed for IBS and to determine the factors associated with its alteration. Methods : Our cross-sectional, monocentric and prospective study was carried out in the outpatient department between February 2019 and January 2020. QOL was measured via MOS SF-36 questionnaire translated to Tunisian dialect. An association between epidemiological and clinical factors and impaired QOL was sought by univariate statistical study. Results: One hundred patients were included (mean age 50,53 years-old and sex-ratio 0,53). The average values of physical (PCS) mental (MCS) and global (SF36) QOL scores were 42,5%, 39,9% and 41,2% respectively. They were all below the general populations average values. The factors associated with an alteration in both the physical and psychological QOL were female sex, low level of education, unemployment or work in the private sector, low socioeconomic level, hypertension, hypothyroidism and overweight and obesity. Conclusion : Functional bowel disorders affect the QOL of patients. The modifiable associated factor scan be the subject of preventive actions to optimize the management of this pathology.
Published: 2022

45. TDF-ß signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells

Author: Stampfer, MR, Cipriano, R, Kan, CE, Graham, J, Danielpour, D, and Jackson, MW
Published: 2022

46. Temporal relation between human mobility, climate and COVID-19 disease

Author: Alice M Grimm, Carlos FO Mendes, Eduardo L Brugnago, and MW Beims
Abstract: Using the example of the city of São Paulo (Brazil), in this paper, we analyze the temporal relation between human mobility and meteorological variables with the number of infected individuals by the COVID-19 disease. For the temporal relation, we use the significant values of distance correlation t0(DC), which is a recently proposed quantity capable of detecting nonlinear correlations between time series. The whole period analyzed goes from Feb 26th to Jun 28th, 2020. Fewer movements in Recreation and Transit Stations and the increase of the maximal temperature, {have strong correlations with the number of newly infected cases occurring 17 days after. Furthermore, more significant changes in Grocery and Pharmacy, Parks and Recreation, and sudden changes in the maximal pressure occurring at 10 and 11 days before the disease's beginning are also correlated with it. Scanning the whole period of the data, not only the early stage of the disease, we observe that changes in human mobility primarily affect the disease for 0 to 19 days after. In other words, our results demonstrate the crucial role of the Municipal Decree declaring an emergency in the city to influence the number of infected individuals.
Published: 2022

47. Measurements of W+W−+ ≥ 1 jet production cross-sections in pp collisions at √s = 13 TeV with the ATLAS detector

Author: Aaboud, M, Aad, G, Abbott, B, Abdinov, O, Abeloos, B, Abhayasinghe, DK, Abidi, SH, AbouZeid, OS, Abraham, NL, Abramowicz, H, Abreu, H, Abulaiti, Y, Acharya, BS, Adachi, S, Adamczyk, L, Adelman, J, Adersberger, M, Adiguzel, A, Adye, T, Affolder, AA, Afik, Y, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmadov, F, Aielli, G, Akatsuka, S, Akesson, TPA, Akilli, E, Akimov, AV, Alberghi, GL, Albert, J, Albicocco, P, Verzini, MJA, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alhroob, M, Ali, B, Alimonti, G, Alison, J, Alkire, SP, Allaire, C, Allbrooke, BMM, Allen, BW, Allport, PP, Aloisio, A, Alonso, A, Alonso, F, Alpigiani, C, Alshehri, AA, Alstaty, MI, Gonzalez, BA, Alvarez Piqueras, D, Alviggi, MG, Amadio, BT, Coutinho, YA, Ambroz, L, Amelung, C, Amidei, D, Amor Dos Santos, SP, Amoroso, S, Amrouche, CS, Anastopoulos, C, Ancu, LS, Andari, N, Andeen, T, Anders, CF, Anders, JK, Anderson, KJ, Andreazza, A, Andrei, V, Anelli, CR, Angelidakis, S, Angelozzi, I, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aparisi Pozo, JA, Aperio Bella, L, Arabidze, G, Araque, JP, Araujo Ferraz, V, Araujo Pereira, R, Arce, ATH, Ardell, RE, Arduh, FA, Arguin, J-F, Argyropoulos, S, Armbruster, AJ, Armitage, LJ, Armstrong, A, Arnaez, O, Arnold, H, Arratia, M, Arslan, O, Artamonov, A, Artoni, G, Artz, S, Asai, S, Asbah, N, Ashkenazi, A, Asimakopoulou, EM, Asquith, L, Assamagan, K, Astalos, R, Atkin, RJ, Atkinson, M, Atlay, NB, Augsten, K, Avolio, G, Avramidou, R, Ayoub, MK, Azuelos, G, Baas, AE, Baca, MJ, Bachacou, H, Bachas, K, Backes, M, Bagnaia, P, Bahmani, M, Bahrasemani, H, Bailey, AJ, Baines, JT, Bajic, M, Bakalis, C, Baker, OK, Bakker, PJ, Gupta, DB, Baldin, EM, Balek, P, Balli, F, Balunas, WK, Balz, J, Banas, E, Bandyopadhyay, A, Banerjee, S, Bannoura, AAE, Barak, L, Barbe, WM, Barberio, EL, Barberis, D, Barbero, M, Barillari, T, Barisits, M-S, Barkeloo, J, Barklow, T, Barlow, N, Barnea, R, Barnes, SL, Barnett, BM, Barnett, RM, Barnovska-Blenessy, Z, Baroncelli, A, Barone, G, Barr, AJ, Barranco Navarro, L, Barreiro, F, Barreiro Guimaraes da Costa, J, Bartoldus, R, Barton, AE, Bartos, P, Basalaev, A, Bassalat, A, Bates, RL, Batista, SJ, Batlamous, S, Batley, JR, Battaglia, M, Bauce, M, Bauer, F, Bauer, KT, Bawa, HS, Beacham, JB, Beau, T, Beauchemin, PH, Bechtle, P, Beck, HC, Beck, HP, Becker, K, Becker, M, Becot, C, Beddall, A, Beddall, AJ, Bednyakov, VA, Bedognetti, M, Bee, CP, Beermann, TA, Begalli, M, Begel, M, Behera, A, Behr, JK, Bell, AS, Bella, G, Bellagamba, L, Bellerive, A, Bellomo, M, Bellos, P, Belotskiy, K, Belyaev, NL, Benary, O, Benchekroun, D, Bender, M, Benekos, N, Benhammou, Y, Benhar Noccioli, E, Benitez, J, Benjamin, DP, Benoit, M, Bensinger, JR, Bentvelsen, S, Beresford, L, Beretta, M, Berge, D, Bergeaas Kuutmann, E, Berger, N, Bergsten, LJ, Beringer, J, Berlendis, S, Bernard, NR, Bernardi, G, Bernius, C, Bernlochner, FU, Berry, T, Berta, P, Bertella, 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Vetterli, MC, Maira, NV, Pinto, MVB, Vichou, I, Vickey, T, Boeriu, OEV, Viehhauser, GHA, Viel, S, Vigani, L, Villa, M, Perez, MV, Vilucchi, E, Vincter, MG, Vinogradov, VB, Vishwakarma, A, Vittori, C, Vivarelli, I, Vlachos, S, Vogel, M, Vokac, P, Volpi, G, von Buddenbrock, SE, Von Toerne, E, Vorobel, V, Vorobev, K, Vos, M, Vossebeld, JH, Vranjes, N, Milosavljevic, MV, Vrba, V, Vreeswijk, M, Sfiligoj, T, Vuillermet, R, Vukotic, I, Zenis, T, Zivkovic, L, Wagner, P, Wagner, W, Wagner-Kuhr, J, Wahlberg, H, Wahrmund, S, Wakamiya, K, Walbrecht, VM, Walder, J, Walker, R, Walker, SD, Walkowiak, W, Wallangen, V, Wang, AM, Wang, C, Wang, F, Wang, H, Wang, J, Wang, P, Wang, Q, Wang, R-J, Wang, R, Wang, SM, Wang, WT, Wang, W, Wang, WX, Wang, Y, Wang, Z, Wanotayaroj, C, Warburton, A, Ward, CP, Wardrope, DR, Washbrook, A, Watkins, PM, Watson, AT, Watson, MF, Watts, G, Watts, S, Waugh, BM, Webb, AF, Webb, S, Weber, C, Weber, MS, Weber, SA, Weber, SM, Weidberg, AR, Weinert, B, Weingarten, J, Weirich, 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Yeletskikh, I, Yigitbasi, E, Yildirim, E, Yorita, K, Yoshihara, K, Young, CJS, Young, C, Yu, J, Yue, X, Yuen, SPY, Zabinski, B, Zacharis, G, Zaffaroni, E, Zaidan, R, Zaitsev, AM, Zakareishvili, T, Zakharchuk, N, Zalieckas, J, Zambito, S, Zanzi, D, Zaripovas, DR, Zeissner, SV, Zeitnitz, C, Zemaityte, G, Zeng, JC, Zeng, Q, Zenin, O, Zerwas, D, Zgubic, M, Zhang, DF, Zhang, D, Zhang, F, Zhang, G, Zhang, H, Zhang, J, Zhang, L, Zhang, M, Zhang, P, Zhang, R, Zhang, X, Zhang, Y, Zhang, Z, Zhao, P, Zhao, X, Zhao, Y, Zhao, Z, Zhemchugov, A, Zhou, B, Zhou, C, Zhou, L, Zhou, MS, Zhou, M, Zhou, N, Zhou, Y, Zhu, CG, Zhu, HL, Zhu, H, Zhu, J, Zhu, Y, Zhuang, X, Zhukov, K, Zhulanov, V, Zibell, A, Zieminska, D, Zimine, NI, Zimmermann, S, Zinonos, Z, Zinser, M, Ziolkowski, M, Zobernig, G, Zoccoli, A, Zoch, K, Zorbas, TG, Zou, R, Nedden, MZ, Zwalinski, L, Collaboration, ATLAS, Aad, G, Bachas, K, Chiodini, G, Gorini, E, Gravili, F, Longo, L, Primavera, M, Reale, M, Schioppa, E, Spagnolo, S, Ventura, A, ATLAS Collaboration, And, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), ATLAS, Współautorami artykułu są członkowie ATLAS Collaboration w liczbie 2885, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), ATLAS (IHEF, IoP, FNWI), XENON (IHEF, IoP, FNWI), Other Research IHEF (IoP, FNWI), UAM. Departamento de Física Teórica, Aad, G. [0000-0002-6665-4934], Abbott, B. [0000-0002-5888-2734], Abbott, D. C. [0000-0002-7248-3203], Abed Abud, A. [0000-0002-2788-3822], Abeling, K. [0000-0002-1002-1652], Abhayasinghe, D. K. [0000-0002-2987-4006], Abidi, S. H. [0000-0002-8496-9294], AbouZeid, O. S. [0000-0002-8279-9324], Abramowicz, H. [0000-0001-5329-6640], Abreu, H. [0000-0002-1599-2896], Abulaiti, Y. [0000-0003-0403-3697], Abusleme Hoffman, A. C. [0000-0003-0762-7204], Acharya, B. S. [0000-0002-8588-9157], Achkar, B. [0000-0002-0288-2567], Adam, L. [0000-0001-6005-2812], Adam Bourdarios, C. [0000-0002-2634-4958], Adamczyk, L. [0000-0002-5859-2075], Adamek, L. [0000-0003-1562-3502], Adelman, J. [0000-0002-1041-3496], Adiguzel, A. [0000-0001-6644-0517], Adorni, S. [0000-0003-3620-1149], Adye, T. [0000-0003-0627-5059], Affolder, A. A. [0000-0002-9058-7217], Afik, Y. [0000-0001-8102-356X], Agapopoulou, C. [0000-0002-2368-0147], Agaras, M. N. [0000-0002-4355-5589], Aggarwal, A. [0000-0002-1922-2039], Agheorghiesei, C. [0000-0003-3695-1847], Aguilar-Saavedra, J. A. [0000-0002-5475-8920], Ahmad, A. [0000-0001-8638-0582], Ahmadov, F. [0000-0003-3644-540X], Ahmed, W. S. [0000-0003-0128-3279], Ai, X. [0000-0003-3856-2415], Aielli, G. [0000-0002-0573-8114], Akatsuka, S. [0000-0002-1681-6405], Akbiyik, M. [0000-0002-7342-3130], Åkesson, T. P. A. [0000-0003-4141-5408], Akilli, E. [0000-0003-1309-5937], Akimov, A. V. [0000-0002-2846-2958], Al Khoury, K. [0000-0002-0547-8199], Alberghi, G. L. [0000-0003-2388-987X], Albert, J. [0000-0003-0253-2505], Alconada Verzini, M. J. [0000-0003-2212-7830], Alderweireldt, S. [0000-0002-8224-7036], Aleksa, M. [0000-0002-1936-9217], Aleksandrov, I. N. [0000-0001-7381-6762], Alexa, C. [0000-0003-0922-7669], Alexopoulos, T. [0000-0002-8977-279X], Alfonsi, A. [0000-0001-7406-4531], Alfonsi, F. [0000-0002-0966-0211], Alhroob, M. [0000-0001-7569-7111], Ali, B. [0000-0001-8653-5556], Ali, S. [0000-0001-5216-3133], Aliev, M. [0000-0002-9012-3746], Alimonti, G. [0000-0002-7128-9046], Allaire, C. [0000-0003-4745-538X], Allbrooke, B. M. M. [0000-0002-5738-2471], Allport, P. P. [0000-0001-7303-2570], Aloisio, A. [0000-0002-3883-6693], Alonso, F. [0000-0001-9431-8156], Alpigiani, C. [0000-0002-7641-5814], Alvarez Estevez, M. [0000-0002-8181-6532], Alviggi, M. G. [0000-0003-0026-982X], Amaral Coutinho, Y. [0000-0002-1798-7230], Ambler, A. [0000-0003-2184-3480], Ambroz, L. [0000-0002-0987-6637], Amidei, D. [0000-0002-6814-0355], Amor Dos Santos, S. P. [0000-0001-7566-6067], Amoroso, S. [0000-0001-5450-0447], Anastopoulos, C. [0000-0003-1587-5830], Andari, N. [0000-0002-4935-4753], Andeen, T. [0000-0002-4413-871X], Anders, J. K. [0000-0002-1846-0262], Andrean, S. Y. [0000-0002-9766-2670], Andreazza, A. [0000-0001-5161-5759], Angelidakis, S. [0000-0002-8274-6118], Angerami, A. [0000-0001-7834-8750], Anisenkov, A. V. [0000-0002-7201-5936], Annovi, A. [0000-0002-4649-4398], Antel, C. 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Subjects: Plus Plus, 13000 GeV-cms, ((n)jet dilepton) [final state], QC770-798, transverse momentum [jet], 01 natural sciences, Subatomär fysik, Hadron-Hadron scattering (experiments), scattering [p p], Nuclear Experiment, Settore FIS/01, Electroweak interaction, hadronic [jet], mass dependence, upper limit [coupling constant], CERN LHC Coll, kinematics, Distributions, colliding beams [p p], p p: scattering, Astrophysics::High Energy Astrophysical Phenomena, coupling constant: upper limit, jet: multiplicity, Nuclear physics, phase space, Atlas (anatomy), quantum chromodynamics, muon: pair, coupling: (3gauge boson), TeV, ddc:530, Rapidity, High Energy Physics, 010306 general physics, Particle Physics, Particle Physics, LHC, ATLAS, Parton Distributions, final state: ((n)jet dilepton), 010308 nuclear & particles physics, jet: hadronic, Hadron Colliders, Automatic Keywords, dependence [multiplicity], Experimental High Energy Physics, p p: colliding beams, electron, Kjerne- og elementærpartikkelfysikk: 431 [VDP], Atlas detector, (3gauge boson) [coupling], Hadron, jet: transverse momentum, GeV, transverse momentum dependence, High Energy Physics - Experiment, gauge [coupling], W: pair production, High Energy Physics - Experiment (hep-ex), Subatomic Physics, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Pair Production, Quantum chromodynamics, Physics, Jet (fluid), mass: transverse, multiplicity: dependence, lepton: transverse momentum, ATLAS, Zz Production, Nuclear and elementary particle physics: 431 [VDP], medicine.anatomical_structure, jet: production, pair production [W], Subtraction, differential cross section, LHC, multiplicity [jet], anomaly [coupling], Particle Physics - Experiment, perturbation theory [quantum chromodynamics], Nuclear and High Energy Physics, topology, Regular Article - Experimental Physics, 530 Physics, coupling: gauge, jet: associated production, interference, FOS: Physical sciences, differential cross section: measured, measured [differential cross section], Nuclear and particle physics. Atomic energy. Radioactivity, electron muon, 0103 physical sciences, medicine, associated production [jet], quantum chromodynamics: perturbation theory, coupling: anomaly, electroweak interaction, background, High Energy Physics::Phenomenology, Física, W bosons, production [jet], pair [muon], rapidity, Pair production, transverse [mass], High Energy Physics::Experiment, Hadron-hadron collisions, transverse momentum [lepton], experimental results
Abstract: We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; ANID, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS and CEA-DRF/IRFU, France; SRNSFG, Georgia; BMBF, HGF and MPG, Germany; GSRT, Greece; RGC and Hong Kong SAR, China; ISF and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; NWO, Netherlands; RCN, Norway; MNiSW and NCN, Poland; FCT, Portugal; MNE/IFA, Romania; JINR; MES of Russia and NRC KI, Russian Federation; MESTD, Serbia; MSSR, Slovakia; ARRS and MIZS, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SERI, SNSF and Cantons of Bern and Geneva, Switzerland; MOST, Taiwan; TAEK, Turkey; STFC, United Kingdom; DOE and NSF, United States of America. In addition, individual groups and members have received support from BCKDF, CANARIE, Compute Canada, CRC and IVADO, Canada; Beijing Municipal Science & Technology Commission, China; COST, ERC, ERDF, Horizon 2020 and Marie Sklodowska-Curie Actions, European Union; Investissements d'Avenir Labex, Investissements d'Avenir Idex and ANR, France; DFG and AvH Foundation, Germany; Herakleitos, Thales and Aristeia programmes co-financed by EU-ESF and the Greek NSRF, Greece; BSF-NSF and GIF, Israel; La Caixa Banking Foundation, CERCA Programme Generalitat de Catalunya and PROMETEO and GenT Programmes Generalitat Valenciana, Spain; Goran Gustafssons Stiftelse, Sweden; The Royal Society and Leverhulme Trust, United Kingdom., Fiducial and differential cross-section measurements of W+W− production in association with at least one hadronic jet are presented. These measurements are sensitive to the properties of electroweak-boson self-interactions and provide a test of perturbative quantum chromodynamics and the electroweak theory. The analysis is performed using proton-proton collision data collected at p s = 13TeV with the ATLAS experiment, corresponding to an integrated luminosity of 139 fb−1. Events are selected with exactly one oppositely charged electron-muon pair and at least one hadronic jet with a transverse momentum of pT > 30 GeV and a pseudorapidity of | | < 4.5. After subtracting the background contributions and correcting for detector effects, the jet-inclusive W+W−+ 1 jet fiducial cross-section and W+W−+ jets differential cross-sections with respect to several kinematic variables are measured. These measurements include leptonic quantities, such as the lepton transverse momenta and the transverse mass of the W+W− system, as well as jet-related observables such as the leading jet transverse momentum and the jet multiplicity. Limits on anomalous triple-gauge-boson couplings are obtained in a phase space where interference between the Standard Model amplitude and the anomalous amplitude is enhanced., ANPCyT, YerPhI, Armenia, Australian Research Council, BMWFW, Austria, Austrian Science Fund (FWF), Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP), Natural Sciences and Engineering Research Council of Canada (NSERC), NRC, Canada, Canada Foundation for Innovation, CERN, ANID, Chile, Chinese Academy of Sciences, Ministry of Science and Technology, China, National Natural Science Foundation of China (NSFC), Departamento Administrativo de Ciencia, Tecnologia e Innovacion Colciencias, Ministry of Education, Youth & Sports - Czech Republic Czech Republic Government Czech Republic Government, DNRF, Denmark Danish Natural Science Research Council, Centre National de la Recherche Scientifique (CNRS) CEA-DRF/IRFU, France, SRNSFG, Georgia, Federal Ministry of Education & Research (BMBF), HGF, Germany Max Planck Society, Greek Ministry of Development-GSRT, RGC, China Hong Kong SAR, China, Israel Science Foundation Benoziyo Center, Israel, Istituto Nazionale di Fisica Nucleare (INFN), Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT) Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT) Japan Society for the Promotion of Science, CNRST, Morocco, Netherlands Organization for Scientific Research (NWO) Netherlands Government, RCN, Norway, Ministry of Science and Higher Education, Poland NCN, Poland, Portuguese Foundation for Science and Technology European Commission, MNE/IFA, Romania, JINR, Russian Federation NRC KI, Russian Federation, Ministry of Education, Science & Technological Development, Serbia, MSSR, Slovakia, Slovenian Research Agency - Slovenia MIZS, Slovenia, DST/NRF, South Africa, Spanish Government, SRC, Sweden Wallenberg Foundation, Sweden, SERI, Switzerland Swiss National Science Foundation (SNSF), Canton of Bern, Switzerland Canton of Geneva, Switzerland, Ministry of Science and Technology, Taiwan, Ministry of Energy & Natural Resources - Turkey, UK Research & Innovation (UKRI), Science & Technology Facilities Council (STFC), United States Department of Energy (DOE) National Science Foundation (NSF), BCKDF, Canada CANARIE, Canada Compute Canada, Canada CRC, Canada IVADO, Canada, Beijing Municipal Science AMP; Technology Commission, China, COST, European Union European Research Council (ERC) ERDF, European Union Horizon 2020, European Union Marie Sklodowska-Curie Actions, European Union, French National Research Agency (ANR), German Research Foundation (DFG), Alexander von Humboldt Foundation, Herakleitos programme - EU-ESF, Greece Thales Group Aristeia programme - EU-ESF, Greece Greek NSRF, Greece, BSF-NSF, Israel, German-Israeli Foundation for Scientific Research and Development, La Caixa Banking Foundation, Spain CERCA Programme Generalitat de Catalunya, Spain PROMETEO Programme Generalitat Valenciana, Spain GenT Programme Generalitat Valenciana, Spain, Goran Gustafssons Stiftelse, Sweden, Royal Society of London, Leverhulme Trust, Azerbaijan National Academy of Sciences (ANAS), SSTC, Belarus, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ)
Published: 2021
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48. Observation of $$ {\Lambda}_b^0 $$ → D+pπ−π− and $$ {\Lambda}_b^0 $$ → D*+pπ−π− decays

Author: Aaij, R, Abdelmotteleb, ASW, Abellán Beteta, C, Abudinén, F, Ackernley, T, Adeva, B, Adinolfi, M, Afsharnia, H, Agapopoulou, C, Aidala, CA, Aiola, S, Ajaltouni, Z, Akar, S, Albrecht, J, Alessio, F, Alexander, M, Alfonso Albero, A, Aliouche, Z, Alkhazov, G, Alvarez Cartelle, P, Amato, S, Amey, JL, Amhis, Y, An, L, Anderlini, L, Andersson, M, Andreianov, A, Andreotti, M, Archilli, F, Artamonov, A, Artuso, M, Arzymatov, K, Aslanides, E, Atzeni, M, Audurier, B, Bachmann, S, Bachmayer, M, Back, JJ, Baladron Rodriguez, P, Balagura, V, Baldini, W, Baptista De Souza Leite, J, Barbetti, M, Barlow, RJ, Barsuk, S, Barter, W, Bartolini, M, Baryshnikov, F, Basels, JM, Bashir, S, Bassi, G, Batsukh, B, Battig, A, Bay, A, Beck, A, Becker, M, Bedeschi, F, Bediaga, I, Beiter, A, Belavin, V, Belin, S, Bellee, V, Belous, K, Belov, I, Belyaev, I, Bencivenni, G, Ben-Haim, E, Berezhnoy, A, Bernet, R, Berninghoff, D, Bernstein, HC, Bertella, C, Bertolin, A, Betancourt, C, Betti, F, Bezshyiko, Ia, 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Kubat, J, Kucharczyk, M, Kudryavtsev, V, Kuindersma, HS, Kunde, GJ, Kvaratskheliya, T, Lacarrere, D, Lafferty, G, Lai, A, Lampis, A, Lancierini, D, Lane, JJ, Lane, R, Lanfranchi, G, Langenbruch, C, Langer, J, Lantwin, O, Latham, T, Lazzari, F, Le Gac, R, Lee, SH, Lefèvre, R, Leflat, A, Legotin, S, Leroy, O, Lesiak, T, Leverington, B, Li, H, Li, P, Li, S, Li, Y, Li, Z, Liang, X, Lin, T, Lindner, R, Lisovskyi, V, Litvinov, R, Liu, G, Liu, H, Liu, Q, Liu, S, Lobo Salvia, A, Loi, A, Lomba Castro, J, Longstaff, I, Lopes, JH, López Soliño, S, Lovell, GH, Lu, Y, Lucarelli, C, Lucchesi, D, Luchuk, S, Lucio Martinez, M, Lukashenko, V, Luo, Y, Lupato, A, Luppi, E, Lupton, O, Lusiani, A, Lyu, X, Ma, L, Ma, R, Maccolini, S, Machefert, F, Maciuc, F, Macko, V, Mackowiak, P, Maddrell-Mander, S, Madejczyk, O, Madhan Mohan, LR, Maev, O, Maevskiy, A, Majewski, MW, Malczewski, JJ, Malde, S, Malecki, B, Malinin, A, Maltsev, T, Malygina, H, Manca, G, Mancinelli, G, Manuzzi, D, Marangotto, D, Maratas, J, Marchand, JF, Marconi, U, Mariani, S, Marin Benito, C, Marinangeli, M, Marks, J, Marshall, AM, Marshall, PJ, Martelli, G, Martellotti, G, Martinazzoli, L, Martinelli, M, Martinez Santos, D, Martinez Vidal, F, Massafferri, A, Materok, M, Matev, R, Mathad, A, Matiunin, V, Matteuzzi, C, Mattioli, KR, Mauri, A, Maurice, E, Mauricio, J, Mazurek, M, McCann, M, Mcconnell, L, Mcgrath, TH, Mchugh, NT, McNab, A, McNulty, R, Mead, JV, Meadows, B, Meier, G, Melnychuk, D, Meloni, S, Merk, M, Merli, A, Meyer Garcia, L, Mikhasenko, M, Milanes, DA, Millard, E, Milovanovic, M, Minard, M-N, Minotti, A, Minzoni, L, Mitchell, SE, Mitreska, B, Mitzel, DS, Mödden, A, Mohammed, RA, Moise, RD, Mokhnenko, S, Mombächer, T, Monroy, IA, Monteil, S, Morandin, M, Morello, G, Morello, MJ, Moron, J, Morris, AB, Morris, AG, Mountain, R, Mu, H, Muheim, F, Mulder, M, Müller, D, Müller, K, Murphy, CH, Murray, D, Murta, R, Muzzetto, P, Naik, P, Nakada, T, Nandakumar, R, Nanut, T, Nasteva, I, Needham, M, Neri, N, Neubert, 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Ponce, S, Popov, D, Popov, S, Poslavskii, S, Prasanth, K, Promberger, L, Prouve, C, Pugatch, V, Puill, V, Punzi, G, Qi, H, Qian, W, Qin, N, Quagliani, R, Raab, NV, Rabadan Trejo, RI, Rachwal, B, Rademacker, JH, Rama, M, Ramos Pernas, M, Rangel, MS, Ratnikov, F, Raven, G, Reboud, M, Redi, F, Reiss, F, Remon Alepuz, C, Ren, Z, Renaudin, V, Ribatti, R, Ricci, AM, Ricciardi, S, Rinnert, K, Robbe, P, Robertson, G, Rodrigues, AB, Rodrigues, E, Rodriguez Lopez, JA, Rodriguez Rodriguez, ERR, Rollings, A, Roloff, P, Romanovskiy, V, Romero Lamas, M, Romero Vidal, A, Roth, JD, Rotondo, M, Rudolph, MS, Ruf, T, Ruiz Fernandez, RA, Ruiz Vidal, J, Ryzhikov, A, Ryzka, J, Saborido Silva, JJ, Sagidova, N, Sahoo, N, Saitta, B, Salomoni, M, Sanchez Gras, C, Santacesaria, R, Santamarina Rios, C, Santimaria, M, Santovetti, E, Saranin, D, Sarpis, G, Sarpis, M, Sarti, A, Satriano, C, Satta, A, Saur, M, Savrina, D, Sazak, H, Scantlebury Smead, LG, Scarabotto, A, Schael, S, Scherl, S, Schiller, M, Schindler, H, 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Thomas, E, Thompson, DJD, Thomson, KA, Tilquin, H, Tisserand, V, T’Jampens, S, Tobin, M, Tomassetti, L, Tong, X, Torres Machado, D, Tou, DY, Trifonova, E, Trilov, SM, Trippl, C, Tuci, G, Tully, A, Tuning, N, Ukleja, A, Unverzagt, DJ, Ursov, E, Usachov, A, Ustyuzhanin, A, Uwer, U, Vagner, A, Vagnoni, V, Valassi, A, Valenti, G, Valls Canudas, N, Van Beuzekom, M, Van Dijk, M, Van Hecke, H, Van Herwijnen, E, Van Veghel, M, Vazquez Gomez, R, Vazquez Regueiro, P, Vázquez Sierra, C, Vecchi, S, Velthuis, JJ, Veltri, M, Venkateswaran, A, Veronesi, M, Vesterinen, M, Vieira, D, Vieites Diaz, M, Viemann, H, Vilasis-Cardona, X, Vilella Figueras, E, Villa, A, Vincent, P, Volle, FC, Vom Bruch, D, Vorobyev, A, Vorobyev, V, Voropaev, N, Vos, K, Waldi, R, Walsh, J, Wang, C, Wang, J, Wang, M, Wang, R, Wang, Y, Wang, Z, Ward, JA, Watson, NK, Weber, SG, Websdale, D, Weisser, C, Westhenry, BDC, White, DJ, Whitehead, M, Wiederhold, AR, Wiedner, D, Wilkinson, G, Wilkinson, M, Williams, I, Williams, M, Williams, MRJ, Wilson, FF, Wislicki, W, Witek, M, Witola, L, Wormser, G, Wotton, SA, Wu, H, Wyllie, K, Xiang, Z, Xiao, D, Xie, Y, Xu, A, Xu, J, Xu, L, Xu, M, Xu, Q, Xu, Z, Yang, D, Yang, S, Yang, Y, Yang, Z, Yao, Y, Yeomans, LE, Yin, H, Yu, J, Yuan, X, Yushchenko, O, Zaffaroni, E, Zavertyaev, M, Zdybal, M, Zenaiev, O, Zeng, M, Zhang, D, Zhang, L, Zhang, S, Zhang, Y, Zharkova, A, Zhelezov, A, Zheng, Y, Zhou, T, Zhou, X, Zhou, Y, Zhovkovska, V, Zhu, X, Zhu, Z, Zhukov, V, Zonneveld, JB, Zou, Q, Zucchelli, S, Zuliani, D, Zunica, G, Belyaev, I [0000-0002-7458-7030], and Apollo - University of Cambridge Repository
Subjects: Hadron-Hadron Scattering, Regular Article - Experimental Physics, Flavour Physics, B Physics, Branching fraction
Abstract: The multihadron decays $$ {\Lambda}_b^0 $$ Λ b 0 → D+pπ−π− and $$ {\Lambda}_b^0 $$ Λ b 0 → D*+pπ−π− are observed in data corresponding to an integrated luminosity of 3 fb−1, collected in proton-proton collisions at centre-of-mass energies of 7 and 8 TeV by the LHCb detector. Using the decay $$ {\Lambda}_b^0 $$ Λ b 0 → $$ {\Lambda}_c^{+} $$ Λ c + π+π−π− as a normalisation channel, the ratio of branching fractions is measured to be$$ \frac{\mathcal{B}\left({\Lambda}_b^0\to {D}^{+}p{\pi}^{-}{\pi}^{-}\right)}{\mathcal{B}\left({\Lambda}_b^0\to {\Lambda}_c^0{\pi}^{+}{\pi}^{-}{\pi}^{-}\right)}\times \frac{\mathcal{B}\left({D}^{+}\to {K}^{-}{\pi}^{+}{\pi}^{+}\right)}{\mathcal{B}\left({\Lambda}_c^0\to {pK}^{-}{\pi}^{-}\right)}=\left(5.35\pm 0.21\pm 0.16\right)\%, $$ B Λ b 0 → D + p π − π − B Λ b 0 → Λ c 0 π + π − π − × B D + → K − π + π + B Λ c 0 → pK − π − = 5.35 ± 0.21 ± 0.16 % , where the first uncertainty is statistical and the second systematic. The ratio of branching fractions for the $$ {\Lambda}_b^0 $$ Λ b 0 → D*+pπ−π− and $$ {\Lambda}_b^0 $$ Λ b 0 → D+pπ−π− decays is found to be$$ \frac{\mathcal{B}\left({\Lambda}_b^0\to {D}^{\ast +}p{\pi}^{-}{\pi}^{-}\right)}{\mathcal{B}\left({\Lambda}_b^0\to {D}^{+}p{\pi}^{-}{\pi}^{-}\right)}\times \left(\mathcal{B}\left({D}^{\ast +}\to {D}^{+}{\pi}^0\right)+\mathcal{B}\left({D}^{\ast +}\to {D}^{+}\gamma \right)\right)=\left(61.3\pm 4.3\pm 4.0\right)\%. $$ B Λ b 0 → D ∗ + p π − π − B Λ b 0 → D + p π − π − × B D ∗ + → D + π 0 + B D ∗ + → D + γ = 61.3 ± 4.3 ± 4.0 % .
Published: 2022

49. Effects of Microabrasion Prior to In-office Bleaching on Hydrogen Peroxide Permeability, Color Change, and Enamel Morphology

Author: AD Loguercio, LJC Vargas, MW Favoreto, HF Andrade, CP F Borges, A Dávila-Sánchez, A Reis, and CP Mora
Subjects: General Dentistry
Abstract: SUMMARY Purpose: This study evaluated hydrogen peroxide (HP) diffusion within the pulp chamber, as well as color change and the surface morphology of teeth subjected to various microabrasion (MA) protocols associated or not with in-office (IO) bleaching. Methods: Forty sound premolars were randomly divided into the following four groups (n=10): no treatment (NC); IO bleaching only; IO immediately after MA (IMA), and IO seven days after MA (7MA). After treatments, the HP concentration (μg/mL) within the pulp chamber was determined using ultraviolet-visible (UV-Vis) spectrophotometry. The color change (ΔE*) was evaluated using the digital spectrophotometer before and 1 week after bleaching. The surface morphology was evaluated by scanning electron microscope (SEM). Data from each test were submitted to one-way ANOVA and Tukey tests (α=0.05). Results: All experimental groups exhibited higher HP concentrations compared to the NC group (p
Published: 2021

50. Attitudes towards animals and belief in animal mind among first-year veterinary students before and after an introductory animal welfare course

Author: MW Jorgensen, Suzanne T. Millman, Jared A. Danielson, Anna K. Johnson, Jesse Robbins, and Rebecca L. Parsons
Subjects: Medical education, General Veterinary, Animal welfare, Animal Science and Zoology, Psychology, General Biochemistry, Genetics and Molecular Biology
Abstract: Veterinarians are increasingly looked to for guidance on matters relating to animal welfare, yet little is known about US veterinary students’ attitudes and beliefs about animals. In 2019, we surveyed all first-year veterinary students at a major US veterinary college (n = 123) before and after taking a required one-credit introductory animal welfare course. Attitudes were measured using the Pests, Pets and Profit (PPP) scale and belief in animal mind (BAM) was measured using anad hocmeasure adapted from previous work. Pre- and post-course comparisons indicated the introductory animal welfare course had no immediate effect on veterinary students’ attitudes or BAM. Veterinary students’ attitudes were most positive for animals considered pets, followed by pests and those used for profit. Students believed most species possess a wide variety of mental capacities, including many secondary emotions often considered uniquely human (eg guilt, embarrassment, jealousy). Sociodemographic variables consistently associated with more positive attitudes towards animals were: female gender, vegetarianism and liberal political ideology. Preferring a career involving large or food animal practice was consistently associated with less positive attitudes towards animals. Belief in animal mind explained 3% of the variation in attitude scores, whereas sociodemographic variables explained 49% of variation in attitude scores. Female gender, vegetarianism and preferring small (vs large or food animal practice) were all associated with greater BAM scores. Understanding veterinary student attitudes towards animals and beliefs about the mental capacities of animals is important when evaluating a veterinarian's ability to adhere to their oath.
Published: 2021

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