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The fundamental moment of prosthetic rehabilitation is the "temporary". Although the meaning of the term diminishes its importance, the provisional has fundamental biological, aesthetic and functional functions. The oral cavity must maintain an adequate level of oral hygiene to carry out this delicate phase in the best possible way; a result achieved only with the collaboration of the prosthetic dentist with the hygienist and the patient, as if they were a biological system in motion. The different methods of hygiene are effective in maintaining a good level of oral health; but they could, if too aggressive, affect the prosthetic restoration. Our objective in vitro is to understand, after applying a known bacterial load, which hygiene method is the most effective in removing bacterial biofilm but at the same time is less aggressive towards resinous material.

Several conditions as trauma, cancer surgical resection, fractures, congenital malformations and periodontitis could bring alveolar bone defects. To avoid more invasive and less predictable regenerative procedures, Stem cells of different origins as pluripotent Embryonic Stem Cells (ESCs), undifferentiated multipotent Mesenchymal Stem Cells (MSCs) and Induced Pluripotent Stem Cells (iPSCs) were proposed as possible alternative. IPSCs have potential for proliferation and differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm and mesoderm. According with their ability to involve in several cells type, Induced Pluripotent Stem Cells (iPSCs) could be proposed as alternative in regeneration either of mineralized tooth components or supporting tissue. The aim of this brief review is to describe clinical applications of Induced Pluripotent Stem Cells (iPSCs) in oral bone regeneration to employ their use in tissue regeneration in dentistry.

The Pamela apparatus will allow precise measurements of cosmic rays in Low Earth Orbit, mainly focusing on the antiparticles component. The apparatus is now ready for flight, and the launch is foreseen during June 2006. The paper briefly reports the status of the experiment, and the performances of the various components as measured before the launch.

YODA++ is a proposal for a semi-automated data handling and analysis system for the PAMELA space experiment. The core of the routines have been developed to process a stream of raw data downlinked from the Resurs DK1 satellite (housing PAMELA) to the ground station in Moscow. Raw data consist of scientific data and are complemented by housekeeping information. Housekeeping information will be analyzed within a short time from download (1 h) in order to monitor the status of the experiment and to foreseen the mission acquisition planning. A prototype for the data visualization will run on an APACHE TOMCAT web application server, providing an off-line analysis tool using a browser and part of code for the system maintenance. Data retrieving development is in production phase, while a GUI interface for human friendly monitoring is on preliminary phase as well as a JavaServerPages/JavaServerFaces (JSP/JSF) web application facility. On a longer timescale (1–3 h from download) scientific data are analyzed. The data storage core will be a mix of CERNs ROOT files structure and MySQL as a relational database. YODA++ is currently being used in the integration and testing on ground of PAMELA data. 2005 Published by Elsevier Ltd on behalf of COSPAR.

YODA is a semi-automated data handling and analysis system for the PAMELA space experiment. The core of the routines have been developed to process a stream of raw data downlinked from the Resurs DK1 satellite (housing PAMELA) to the ground station in Moscow. Raw data consist of scientific data and engineering information. Housekeeping information are analyzed in a short time from download ( ≃ hours ) in order to monitor the status of the experiment and for the mission planning. A prototype for the data visualization runs on an APACHE TOMCAT web application server, providing an off-line analysis tool using a browser and part of code for the system maintenance. A quicklook system with GUI interface is used for operator monitoring and fast macrocommand issuing. On a longer timescale scientific data are analyzed, calibrations performed and the database adjourned. The data storage core is composed of CERN's ROOT files structure and MySQL as a relational database. YODA++ is currently being used in the integration and testing of ground PAMELA data.

The Sirad experiment aims to measure with great precision the cosmic ray radiation environment on the outside of the International Space Station. The detector, composed of a stack of 32 silicon detectors arranged in X–Y pattern and surmounted by a scintillator system, is capable of detecting nuclei from protons to Iron in the energy range between ≃ 30 MeV / n and ≃ 5 GeV / n .