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Additional file 2: Figure S2. Distribution of methylation by the genotypes of mQTL SNPs in Table 1.

Additional file 3: Figure S3. Sensitivity analysis by subgroup analysis within NY fetal samples, NY adult samples and TX samples.

Supplemental Material, sj-docx-1-cpc-10.1177_10556656211010060 for Birth Defect Co-Occurrence Patterns Among Infants With Cleft Lip and/or Palate by Maria Luisa Navarro Sanchez, Renata H. Benjamin, Laura E. Mitchell, Peter H. Langlois, Mark A. Canfield, Michael D. Swartz, Angela E. Scheuerle, Daryl A. Scott, Hope Northrup, Christian P. Schaaf, Joseph W. Ray, Scott D. McLean, Han Chen, Philip J. Lupo and A.J. Agopian in The Cleft Palate-Craniofacial Journal

Additional file 5: Figure S5. Two-sample MR for causal effect from mQTL to CHD through CpG.

Additional file 6: Figure S6. Sample QC. A. Median intensities for methylated channels vs unmethylated channels. No bad quality sample was identified. B. Distribution of methylation beta values across samples. One sample (internal ID: NY07) showed abnormal distribution. C. Principal components of Epigenomic profiles. Red color: fetal heart samples; Green color: adult heart samples; Black color: ages unknown. One sample (NY07) was removed from the analysis.

Additional file 1: Figure S1 . Distribution of modeling fitting statistics evaluating genetic-epigenetic association. Left: Volcano plot of coefficient estimates. Right: model goodness-of-fit R2.

Additional file 4: Figure S4. Distribution of posterior probabilities (PP0 – PP4) from colocalization analysis with two GWAS phases and five eQTL heart tissues.

The Inaugural Symposium on Childhood Cancer Health Disparities was held in Houston, Texas, on November 2, 2016. The symposium was attended by 109 scientists and clinicians from diverse disciplinary backgrounds with interests in pediatric cancer disparities and focused on reviewing our current knowledge of disparities in cancer risk and outcomes for select childhood cancers. Following a full day of topical sessions, everyone participated in a brainstorming session to develop a working strategy for the continued expansion of research in this area. This meeting was designed to serve as a springboard for examination of childhood cancer disparities from a more unified and systematic approach and to enhance awareness of this area of need.