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El cáncer en la cavidad nasal y senos paranasales en niños es un problema serio en la población pediátrica principalmente por la inespecificidad de los síntomas que lleva a que pasen años o meses antes de la sospecha de una patología neoplásica, es por esto que se realiza este articulo con el objetivo de presentar la casuística de los tumores de nariz y senos paranasales recogida durante 5 años, en un hospital pediátrico de tercer nivel en la cuidad de Bogotá y se revisan la características imagenológicas para el diagnóstico de estos con algunos casos clínicos como ejemplo.

This work was partially supported by the Spanish Ministry of Science and Technology through the projects TIN2016-80920-R and PID2019-105396RB-I00, the Regional Government of Andalusia through the project A-TIC-458-UGR18 (DeepL-ISCO) within the Andalucia ERDF2014-20 Operational Programme, and the University of Malaga through the I Plan Propio de Investigacion., The use of unmanned aerial vehicles with multiple onboard sensors has grown significantly in tasks involving terrain coverage such as environmental and civil monitoring, disaster management, and forest fire fighting. Many of these tasks require a quick and early response, which makes maximizing the land covered from the flight path a challenging objective, especially when the area to bemonitored is irregular, large and includesmany blind spots. Accordingly, state-of-the-art total viewshed algorithms can be of great help to analyze large areas and find new paths providing maximum visibility. This article shows how the total viewshed computation is a valuable tool for generating paths that provide maximum visibility during a flight. We introduce a new heuristic called visibility-based path planning (VPP) that offers a different solution to the path planning problem. VPP identifies the hidden areas of the target territory to generate a path that provides the highest visual coverage. Simulation results show that VPP can cover up to 98.7% of theMontes deMalaga Natural Park and 94.5% of the Sierra de las Nieves National Park, both located within the province of Malaga (Spain) and chosen as regions of interest. In addition, a real flight test confirmed the high visibility achieved using VPP. Our methodology and analysis can be easily applied to enhance monitoring in other large outdoor areas., Spanish Government TIN2016-80920-R PID2019-105396RB-I00, Regional Government of Andalusia within the Andalucia ERDF2014-20 Operational Programme A-TIC-458-UGR18, University of Malaga through the I Plan Propio de Investigacion

espanolEl objetivo del estudio es desarrollar una metodologia de mejora para un proceso de produccion de arneses automotrices mediante la implementacion de un sistema de monitoreo electronico por codigo de barras, que permita obtener la trazabilidad de los productos procesados e identificar el origen, o causa raiz de los problemas de calidad. La metodologia consta de un diagnostico previo del area, el desarrollo y pruebas del programa, la implementacion del sistema dentro del area, asi como la capacitacion del personal involucrado. Se encontraron los principales defectos del area de inyeccion de espuma, y con ayuda del sistema de trazabilidad se logro identificar las causas raiz de los mismos, por lo que se tomaron acciones especificas. Despues de tres meses de implementacion se redujo en 15% el porcentaje del principal defecto encontrado. EnglishThe objective of this study is to develop a methodology for improving an automotive harness manufacturing process through the implementation of an electronic bar code monitoring system that allows obtaining the traceability of the processed products and identifying the origin of the quality problems. The methodology consists of an initial diagnosis of the area, the development and testing of the program, and the implementation of the system within the area, as well as the training of the personnel involved. The main defects of the area of foam injection were found, and with the help of the traceability system it was possible to identify the root causes of them, for which specific actions were taken. After three months of implementation the percentage was reduced by 15% of the main defect found.

Latent fingerprint identification is one of the most essential identification procedures in criminal investigations. Addressing this task is challenging as (i) it requires analyzing massive databases in reasonable periods and (ii) it is commonly solved by combining different methods with very complex datadependencies, which make fully exploiting heterogeneous CPU-GPU systems very complex. Most efforts in this context focus on improving the accuracy of the approaches and neglect reducing the processing time. Indeed, the most accurate approach was designed for one single thread. This work introduces ALFI (Asynchronous processing for Latent Fingerprint Identification), the fastest methodology for latent fingerprint identification maintaining high accuracy. ALFI fully exploits all the resources of CPU-GPU systems using asynchronous processing and fine-coarse parallelism for analyzing massive databases. Our approach reduces idle times in processing and fully exploits the inherent parallelism of comparing latent fingerprints to fingerprint impressions. We analyzed the performance of ALFI on Linux and Windows operating systems using the well-known NIST/FVC databases. Experimental results reveal that ALFI is in average 22x faster than the state-of-the-art algorithm, reaching a value of 44.7x for the best-studied case., Spanish Government TIN2016-80920-R, University of Malaga through the U-Smart-Drive project, I Plan Propio de Investigacion, Postdoctoral Fellowship of the Research Foundation of Flanders (FWO) 170303/12X1619N, ISAC Marylou Ingram Scholar, Spanish Government RYC-2015-18136

This study evaluated the effects of vitamin E (Vit E) and selenium (Se) supplementation on mRNA abundance of antioxidant, immune response, and tight junction genes, as well as taxonomic and functional profiles of ileal microbiota of broilers exposed to daily 4-h elevated temperature during d 28 to 35. A total of 640-day-old Cobb male broiler chicks were randomly allocated to 32 floor pens in a 2 x 2 factorial arrangement that included ambient temperature (thermoneutral [TN] or heat stress [HS]) and dietary treatments (basal diet or Vit E + Se). Vit E and organic Se were added to the basal diet at the rate of 250 mg/kg and 1 mg/kg, respectively. Liver and jejunum tissue samples were taken on d 27 (1 bird/pen), d 28 and d 35 (2 birds/pen) from birds for qPCR analysis. Data were subjected to a 2-way ANOVA using the GLM procedure of JMP. Ileal contents were taken on d 27 and d 35 for microbial profiling. Microbiota data were analyzed in QIIME 2 and significance between treatments identified linear discriminant analysis effect size (LEfSe, P < 0.05). Dietary Vit E/Se significantly downregulated the mRNA levels of HSPs in liver and jejunal tissues of the HS-challenged birds both on d 28 and d 35. Moreover, mRNA abundance of TLR2, INF alpha, IFN gamma, IL-1 beta, IL-10, and iNOS in the liver were significantly downregulated in birds fed the Vit E/Se diet on d 35. However, dietary treatment had no significant impact on oxidative stress, immunity, and gut integrity related genes analyzed in jejunal tissues on d 28 and d 35, except downregulation of IFN gamma on d 35 (P = 0.052). LEfSe analysis revealed that Lachnospiraceae FE2018 and Ruminococcaceae NK4A214 groups was enriched in the Vit E/Se birds on d 35. Moreover, PICRUSt analysis predicted significant functional differences among the treatment groups. In conclusion, dietary supplementation of Vit E/Se mitigated the negative effects of HS potentially via improving antioxidant status, regulating cytokine responses and modifying ileal microbiota and its function. USDA-NIFA Hatch funds; Virginia Agricultural Experiment Station, Virginia Tech Published version This work was supported, in part, by USDA-NIFA Hatch funds to the Virginia Agricultural Experiment Station, Virginia Tech.

There is growing awareness that variability in the nutritional quality of Ca sources has significant effects on gastrointestinal pH, P and amino acid digestibility, exogenous enzyme efficacy and the microbial population in the gastrointestinal tract of broilers. In this regard, the interest in moving toward a digestible Ca system is gaining traction and the apparent ileal digestibility (AID) or standardized ileal digestibility (SID) coefficients for Ca in ingredients, such as limestone (n = 55), dicalcium phosphate (DCP; n = 21), meat and bone meal (MBM; n = 20), monocalcium phosphate (MCP; n = 12), and plant-based ingredients are available. The aim of this review was to compile the literature evaluating Ca digestibility of feed ingredients for broilers, highlight factors that may influence the digestibility coefficients, and suggest recommendations to move toward a digestible Ca system. There were 11 papers published between 1974 and 2019 focused on the evaluation of Ca digestibility of feed ingredients for broilers. The average ileal Ca digestibility coefficient for limestone was 0.53, DCP was 0.42, MCP was 0.35 and MBM was 0.46. There were no differences in the AID or SID Ca digestibility coefficients within ingredient. The ileal Ca digestibility coefficient for limestone increased (quadratic, P 1:1 or to 16 h for diets with a Ca:NPP ratio

This study evaluated the relationship between salt-soluble protein (SSP) of maize and the apparent ileal digestibility (AID) of complete diets in response to exogenous α-amylase supplementation in broiler chickens. Samples of 12 maize batches originating from the mid-north and northeast of China were analyzed for SSP. Six of the 12 sources of maize with a wide variation of SSP (from 21.1 % to >50 %) were selected. Six maize-soybean meal basal diets were formulated, including each source of maize with or without the addition of α-amylase (Ronozyme® HiStarch; DSM Nutritional Products). A total of 960 day-old male Arbor Acres Plus broiler chickens were randomly allocated to 12 treatments with 8 replicates per treatment in wired cages and fed experimental diets in 2 phases (d 1−14; d 15−28). At d 28, 4 birds selected from each cage were euthanized for evaluation of apparent ileal digestibility (AID) of starch and energy. The addition of α-amylase reduced the feed conversion ratio (FCR) of chickens from 1 to 28 d (1.407 vs. 1.426) compared to the basal diets across maize batches, particularly from 1 to 7 d (1.049 vs. 1.078). An interaction between maize batch and α-amylase supplementation on FCR was detected only at 7 d, when the batch with the lowest SSP exhibited the greatest response to α-amylase. Neither a main effect of α-amylase nor an interaction with maize batch on AID of starch were detected (P > 0.05). Nonetheless, α-amylase supplementation increased ileal digestible energy (IDE) from 12.21 to 12.50 MJ/kg dry matter across maize batches. These increments were mainly driven by the maize batch with the lowest SSP. α-amylase supplementation reduced the variability of IDE from a coefficient variance (CV)=5.2 % to a CV=0.7 % across maize batches. Interestingly, there was a strong negative correlation (r

Predetermined motion time systems (PMTS) are one of various techniques to determine the time to execute a repetitive task, generally used to obtain labor minute costing, set piece-rates, wage-rates and/or incentives in labor intensive industries. One of the most popular PMTS is MODAPTS, a method that divides work in two basic elements: Body part being used, and effort involved to calculate the time needed to complete a task without a chronometer. Kinect is a motion sensor developed to detect human position and movement using several hardware, most notably a depth sensor, a color camera, and a microphone array that provide full body 3D motion capture. A computer software for the establishment of time standards is presented, this software gathers data from Microsoft’s motion analysis technology and associates it to time values using the MODAPTS technique. In order to validate the software tool, results of a wiring harness manufacturing process are presented.

SummaryA study was conducted to evaluate productive performance in laying hens fed diets with reduced nutrient density based on the nutritional contribution of a Buttiauxella phytase in laying-hen diets from 21-57 weeks of age. A commercial laying hen diet was offered ad libitum to the 480 ISA Brown laying hens from 18-21 weeks of age. From 21 weeks onwards, the hens received one of four dietary treatments: a positive control (PC) diet, a down specified diet (DS1) + phytase at 300 FTU/kg, a second down-specified diet (DS2) + phytase at 600 FTU/kg and a third test diet formulated as per DS1 + phytase at 1,200 FTU/kg feed. The PC was formulated based on ISA breeder recommendations. DS1 was formulated with reduction of 0.149% available P, 0.134% Ca, 55 kcal/kg AME, 0.33% CP, digestible amino acids (up to 0.015%) and 0.013% Na based on the contribution of Buttiauxella phytase at 300 FTU/kg. DS2 was formulated with reduction of 0.177% available P, 0.159% Ca, 60 kcal/kg AME, 0.61% CP, digestible amino acids (up to 0.028%) and 0.02% Na based on the contribution of Buttiauxella phytase at 600 FTU/kg. Every dietary treatment was fed to 12 cages containing 10 hens each. The trial treatments did not include a full, DS negative control, as ethical considerations regarding birds' welfare when feeding such diets over such an extended period of time did not permit this. No significant differences were seen in hen-day egg production, feed intake, egg weight, feed to egg mass ratio, shell, yolk or albumen proportion, unsaleable eggs or shell breaking strength in laying hens fed the PC diet or the DS diets with added phytase. Yolk colour increased significantly with phytase supplementation. Supplementing the DS1 diet with 300 FTU and the DS2 diet with 600 FTU resulted in non-significant differences in tibia ash, Ca and P, compared to the PC diet. The data from this study indicated that applying the nutrient contributions for Buttiauxella phytase at 300 and 600 FTU/kg maintained the egg production, BW and egg quality parameters compared to PC. The best economic efficiency value during the whole experimental period was recorded with phytase at 600 FTU/kg when full matrix values are used. When commercial diets are formulated based on ISA breeder recommendations, lowering diet nutrient density while supplementing with phytase reduced the overall diet cost, which should contribute to the profitability of egg production.

Recently, companies have become more interested about well-being and satisfaction of human resources. There is an increased awareness that conditions on the marketplace such as high variety products, demand fluctuations and the high service levels required by customers make it necessary to develop methods and models to measure and predict human performance. As Lean Manufacturing is a popular method used at companies in order to foster productivity and innovation in the industrial environment, we proposed the application of the Ergonomic Value Stream Mapping, a novel tool that aims to improve ergonomic conditions while productive performance indicators are also in focus. This work aims to provide academics and practitioners with a novel tool capable to satisfy current needs in manufacturing environments, regarding cognitive ergonomics assurance at workplaces. The implementation of ErgoVSM on its cognitive modality is an effort for acknowledging the significance of assessing health risks within each workstation at companies.

La herramienta de simulacion se utiliza para realizar representaciones de sistemas productivos y estudiar el flujo de proceso de estos sistemas complejos, sin embargo no existe un esquema metodologico estandarizado para la realizacion de dichos estudios. En este estudio se plantea una propuesta metodologica para la construccion de modelos de simulacion de flujo de aereas productivas dentro de organizaciones manufactureras. La metodologia propone el uso del paquete de simulacion ProModel y una de sus herramientas denominada Stat:Fit. Como resultado final de la investigacion se obtuvo una metodologia compuesta por 9 etapas principales creada para localizar los cuellos de botella dentro de un proceso y fungir como una herramienta de evaluacion y toma de decisiones acerca de la implementacion de propuestas de mejora en cualquier sistema manufacturero y se aplico dicha metodologia para realizar un diagnostico de flujo en el area de carrocerias dentro de la planta de estampado y ensamble de Ford Motor Company ubicada en la ciudad de Hermosillo, Sonora, Mexico. Como resultado de esta investigaci on se obtuvo 1 propuesta de mejora para eliminar el cuello de botella del area de carrocerias y alcanzar el flujo solicitado por la compania sometida a escrutinio, logrando un incremento de 7.88% de unidades producidas respecto al estado inicial del sistema.

Con el fin de conocer el índice de infección por Chlamydia rachomatis, Gardnerella vaginalis y otros gérmenes sexualmente transmisibles en un grupo de gestantes. Se estudiaron 135 mujeres del primer, segundo y tercer trimestre de gestación atendidas en el Hospital de Maternidad Rafael Calvo. Mediante estudios combinados de laboratorio, que incluyeron exámenes directos, cultivos bacteriológicos y técnicas de inmunoensayo, se identificaron los microorganismos infectantes en flujo vaginal, secreción endocervical suero de 83% de los pacientes. Se encontró que el 15,5%, 9,6%, 8,5%, 40%, 8,8% y 0,7% de las gestantes tuvieron infección genital por C. trachomatis, G. vaginalis, T. vaginalis, Candida sp., Streptococcus By N. gonorrhoeae, respectivamente; ninguna paciente fue reactiva para marcador de infección activa por citomegalovirus. La cervicitis y el aborto, como antecedentes, fueron las patologías asociadas más frecuentemente halladas; la ruptura temprana de membranas, tambi6n se presentó en algunas de las pacientes. La significativa proporción de gestantes con infección por bacterias que causan complicaciones en el embarazo, amerita su estudio en el diagnóstico de rutina de la consulta prenatal del Hospital de Maternidad Rafael Calvo.