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1. Additional file 1 of Results of salvage therapy with mini-hyper-CVD and inotuzumab ozogamicin with or without blinatumomab in pre-B acute lymphoblastic leukemia

Author

Kantarjian, Hagop, Haddad, Fadi G., Jain, Nitin, Sasaki, Koji, Short, Nicholas J., Loghavi, Sanam, Kanagal-Shamanna, Rashmi, Jorgensen, Jeffrey, Khouri, Issa, Kebriaei, Partow, Alvarado, Yesid, Kadia, Tapan, Paul, Shilpa, Garcia-Manero, Guillermo, Dabaja, Bouthaina, Yilmaz, Musa, Jacob, Jovitta, Garris, Rebecca, O’Brien, Susan, Ravandi, Farhad, and Jabbour, Elias

Abstract

Additional file 1: Fig. S1. Visual schematic of the A original study design and B modified study design. Fig. S2. Consort diagram. Table S1. Best overall response by salvage status. Fig. S3. Overall survival by treatment modality in Salvage 1. Table S2. Characteristics and treatments of patients who did not undergo allogeneic stem cell transplantation and remained alive and disease free. Fig. S4. Overall survival by TP53 mutation status. Fig. S5. Overall survival by cytogenetic risk. Table S3. Univariate and multivariate analysis for overall survival. Table S4. Characteristics and outcome of patients with hepatic sinusoidal obstruction syndrome.

Published
2023
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2. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

Author

Khoury, Joseph D, Solary, Eric, Abla, Oussama, Akkari, Yassmine, Alaggio, Rita, Apperley, Jane F, Bejar, Rafael, Berti, Emilio, Busque, Lambert, Chan, John KC, Chen, Weina, Chen, Xueyan, Chng, Wee-Joo, Choi, John K, Colmenero, Isabel, Coupland, Sarah E, Cross, Nicholas CP, De Jong, Daphne, Elghetany, M Tarek, Takahashi, Emiko, Emile, Jean-Francois, Ferry, Judith, Fogelstrand, Linda, Fontenay, Michaela, Germing, Ulrich, Gujral, Sumeet, Haferlach, Torsten, Harrison, Claire, Hodge, Jennelle C, Hu, Shimin, Jansen, Joop H, Kanagal-Shamanna, Rashmi, Kantarjian, Hagop M, Kratz, Christian P, Li, Xiao-Qiu, Lim, Megan S, Loeb, Keith, Loghavi, Sanam, Marcogliese, Andrea, Meshinchi, Soheil, Michaels, Phillip, Naresh, Kikkeri N, Natkunam, Yasodha, Nejati, Reza, Ott, German, Padron, Eric, Patel, Keyur P, Patkar, Nikhil, Picarsic, Jennifer, Platzbecker, Uwe, Roberts, Irene, Schuh, Anna, Sewell, William, Siebert, Reiner, Tembhare, Prashant, Tyner, Jeffrey, Verstovsek, Srdan, Wang, Wei, Wood, Brent, Xiao, Wenbin, Yeung, Cecilia, and Hochhaus, Andreas

Subjects
Detection, screening and diagnosis, Hematologic Neoplasms, Human Genome, Clinical Sciences, Oncology and Carcinogenesis, Immunology, Genetics, Humans, World Health Organization, Histiocytosis, 4.1 Discovery and preclinical testing of markers and technologies
Abstract

The upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ systems within a single relational database. This paper summarizes the new WHO classification scheme for myeloid and histiocytic/dendritic neoplasms and provides an overview of the principles and rationale underpinning changes from the prior edition. The definition and diagnosis of disease types continues to be based on multiple clinicopathologic parameters, but with refinement of diagnostic criteria and emphasis on therapeutically and/or prognostically actionable biomarkers. While a genetic basis for defining diseases is sought where possible, the classification strives to keep practical worldwide applicability in perspective. The result is an enhanced, contemporary, evidence-based classification of myeloid and histiocytic/dendritic neoplasms, rooted in molecular biology and an organizational structure that permits future scalability as new discoveries continue to inexorably inform future editions.

Published
2022

3. Publisher Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

Author

Morita, Kiyomi, Wang, Feng, Jahn, Katharina, Hu, Tianyuan, Tanaka, Tomoyuki, Sasaki, Yuya, Kuipers, Jack, Loghavi, Sanam, Wang, Sa A., Yan, Yuanqing, Furudate, Ken, Matthews, Jairo, Little, Latasha, Gumbs, Curtis, Zhang, Jianhua, Song, Xingzhi, Thompson, Erika, Patel, Keyur P., Bueso-Ramos, Carlos E., DiNardo, Courtney D., Ravandi, Farhad, Jabbour, Elias, Andreeff, Michael, Cortes, Jorge, Bhalla, Kapil, Garcia-Manero, Guillermo, Kantarjian, Hagop, Konopleva, Marina, Nakada, Daisuke, Navin, Nicholas, Beerenwinkel, Niko, Futreal, P. Andrew, and Takahashi, Koichi

Subjects
Multidisciplinary, Tumour heterogeneity, Science, Cancer genomics, General Physics and Astronomy, lcsh:Q, General Chemistry, lcsh:Science, Publisher Correction, Acute myeloid leukaemia, General Biochemistry, Genetics and Molecular Biology
Abstract

A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-19902-7

Published
2020

4. Additional file 1 of Outcomes with sequential FLT3-inhibitor-based therapies in patients with AML

Author

Yilmaz, Musa, Alfayez, Mansour, DiNardo, Courtney D., Borthakur, Gautam, Kadia, Tapan M., Konopleva, Marina Y., Loghavi, Sanam, Kanagal-Shamanna, Rashmi, Keyur P. Patel, Jabbour, Elias J., Garcia-Manero, Guillermo, Pemmaraju, Naveen, Pierce, Sherry A., Ghayas, Issa, Short, Nicholas J., Montalban-Bravo, Guillermo, Takahashi, Koichi, Assi, Rita, Alotaibi, Ahmad S., Ohanian, Maro, Andreeff, Michael, Cortes, Jorge E., Hagop M. Kantarjian, Ravandi, Farhad, and Naval G. Daver

Abstract

Additional file 1. Manuscript Supplementary Information.

Published
2020
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