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Concrete with manufactured sand (MSC) requires adequate compressive properties, which may be caused by stone powder. This present study investigated the effect of different stone powder content (0%...

The grey correlation theory and multiple regression method are used to reveal macro performance degradation rules of road concrete under loading and freeze-thaw and drying-wetting cycles; then the correlation between mesoscopic pore structure and residual strength and antifreezing index of concrete is analyzed. Under the freeze-thaw and drying-wetting cycles with 50% loading level, the pore structure parameters that influence concrete strength show the following sequence: fractal dimension > most probable pore size > porosity > less harmful pore. The correlation between strength and pore parameters can be represented with multiple nonlinear equations. A negative correlation is shown between strength and fractal dimension and most probable pore size. Conversely, a positive correlation is shown between strength, porosity, and less harmful pore. Under the freeze-thaw and drying-wetting cycles with 80% loading level, the pore structure parameters that influence concrete strength show another sequence: fractal dimension > porosity > less harmful pore > most probable pore size. The correlation between antifreezing index and pore parameters should be described with multiple linear equations. The relative dynamic elastic modulus shows a positive correlation to most probable pore size, pore surface area, and porosity but a negative correlation to less harmful pore and pore spacing coefficient.

The destructive process of mouse MS-2 fibrosarcoma induced by photodynamic therapy (PDT) with liposome-administered Zn(II)-phthalocyanine (ZnPc) was studied by electron microscopy. Pronounced ultrastructural changes characteristic of apoptosis were observed for several tumour cells, including early occurrence of condensation and margination of chromatin, disappearance of nuclear pores, karyopyknosis, karyorrhexis, protuberance formation at the cell surface and cell fragmentation. The findings indicate that apoptosis was involved in the process of tumour cell death induced by ZnPc-PDT. The detailed mechanism and pathways controlling this phenomenon need to be elucidated further.