1. Bicuspid Aortic Valve Anatomy and Relationship With Devices: The BAVARD Multicenter Registry
- Author
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Tchetche, Didier, de Biase, Chiara, van Gils, Lennart, Parma, Radoslaw, Ochala, Andrzej, Lefevre, Thierry, Hovasse, Thomas, De Backer, Ole, Sondergaard, Lars, Bleiziffer, Sabine, Lange, Rudiger, Kornowski, Ran, Landes, Uri, Norgaard, Bjarne Linde, Biasco, Luigi, Philippart, Raphaël, Molina-Martin de Nicolas, Javier, Mylotte, Darren, Lemee, Caroline, Dumonteil, Nicolas, and Van Mieghem, Nicolas M
- Subjects
Aged, 80 and over ,Male ,Time Factors ,Heart Valve Diseases ,Aortic Valve Stenosis ,Prosthesis Design ,Risk Assessment ,Europe ,Transcatheter Aortic Valve Replacement ,Treatment Outcome ,Bicuspid Aortic Valve Disease ,Risk Factors ,Aortic Valve ,Heart Valve Prosthesis ,Multidetector Computed Tomography ,cardiovascular system ,Humans ,Female ,Registries ,Israel ,Aged ,Retrospective Studies - Abstract
BACKGROUND: Sizing for transcatheter aortic valve implantation in bicuspid aortic valves (BAV) remains controversial.METHODS AND RESULTS: The aim of the BAVARD (Bicuspid Aortic Valve Anatomy and Relationship With Devices) retrospective registry is to capture the sizing ratios used for transcatheter aortic valve implantation in BAV and analyze the second-generation prostheses geometry postimplantation. About 101 patients with BAV along with available pre- and post-transcatheter aortic valve implantation multidetector computed tomography were compared with 88 tricuspid aortic valves (TAV) patients. Preprocedural multidetector computed tomography diagnosed type 0 and type 1 BAV in, respectively, 12.9% and 86.1 % of BAV. At baseline, the ellipticity index was similar between BAV and TAV patients: 1.2±0.1 versus 1.2±0.1, P=0.09. The mean annular oversizing was, respectively, 1.14±0.04 and 1.04±0.04, PCONCLUSIONS: Second-generation prostheses similarly reshape the aortic annulus in TAV and BAV. Prostheses keep consistent diameters from distal edge to 12 mm in TAV and BAV. Prosthesis underexpansion is constantly observed in BAV. Annular-based sizing is accurate in BAV with minimal oversizing. The intercommissural distance, 4 mm above the annulus, could be integrated in gray zones.CLINICAL TRIAL REGISTRATION: URL: https://www.clinicaltrials.gov . Unique identifier: NCT03495050.
- Published
- 2019