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Additional file 5: Figure S3. Forest plot of factors associated with OS (A) and PFS (B) in PSM cohort treated with HAIC 1d versus HAIC 2d. PSM, propensity score matching.

Additional file 2: Table S1. Treatment administration. Table S2. Univariate and multivariate analysis of overall survival and progression-free survival. Table S3. Univariate and multivariate analysis of overall survival and progression-free survival in the PSM cohort. Table S4. Intrahepatic tumor response. Table S5. Baseline characteristics and tumor response within patients performing ELISA detection.

Additional file 1. Methods. The details of ELISA.

Additional file 4: Figure S2. Kaplan-Meier curves of overall survival in BCLC stage C patients receiving HAIC alone (A), HAIC + TKIs (B) and HAIC + TKIs + ICIs (C) in PSM cohort. Kaplan-Meier curves of progression-free survival in BCLC stage C patients receiving HAIC alone (D), HAIC + TKIs (E) and HAIC + TKIs + ICIs (F) in PSM cohort. CI, confidence interval; HR. hazard ratio; PSM, propensity score matching.

Additional file 3: Figure S1. Kaplan-Meier curves of overall survival in BCLC stage C patients receiving HAIC alone (A), HAIC + TKIs (B) and HAIC + TKIs + ICIs (C). Kaplan-Meier curves of progression-free survival in BCLC stage C patients receiving HAIC alone (D), HAIC + TKIs (E) and HAIC + TKIs + ICIs (F). CI, confidence interval; HR. hazard ratio.

Supplemental material, sj-docx-1-tct-10.1177_15330338221117389 for Hepatic Arterial Infusion of Oxaliplatin, Fluorouracil, and Leucovorin Versus Sorafenib for Hepatocellular Carcinoma Refractory to Transarterial Chemoembolization: Retrospective Subgroup Analysis of 2 Prospective Trials by YeXing Huang, LiHong Zhang, MinKe He, ZhiCheng Lai, XiaoYun Bu, DongSheng Wen, QiJiong Li, Li Xu, Wei Wei, YaoJun Zhang, ZhongGuo Zhou, MinShan Chen, RongPing Guo, Ming Shi and Anna Kan in Technology in Cancer Research & Treatment