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Oral squamous cell carcinoma (OSCC), the most frequent head and neck cancer, has a high potential for metastasis. MiR-126 plays an important role in the tumorigenesis of many tumors; however, there were little studies in OSCC. The purpose of our study was to explore how miR-126 and ADAM9 worked on migration and invasion in OSCC.The quantitative Real Time-Polymerase Chain Reaction (qRT-PCR) was applied to detect the mRNA level of miR-126 and ADAM9. The transwell assay was utilized to calculate the migratory and invasive capacities in the OSCC cells. The luciferase report assay was utilized to verify that ADAM9 was a direct target of miR-126.MicroR-126 was downregulated in OSCC tissues and cell lines SCC25 and HSC3. ADAM9 was predicted to be a direct target of miR-126 and was upregulated in the OSCC cells. In addition, miR-126 suppressed the migratory and invasive ability via mediating the expression of ADAM9 by directly targeting its mRNA 3'-noncoding region (UTR), whose partial functions was reversed by ADAM9.MiR-126 inhibited the migratory and invasive capacities of OSCC by directly targeting the 3'-UTR of ADAM9 mRNA. It is suggested that miR-126/ADAM9 axis may play an essential role in inhibiting the abilities of migration and invasion in oral squamous cell carcinoma cells.

Quasielastic scattering of $^{6}\mathrm{He}$ on a $^{12}\mathrm{C}$ target was measured at 82.3 MeV/nucleon. Special care was taken to treat the background subtraction at very small angles. The measured differential cross-sections show a large enhancement at small angles relative to the Rutherford cross-section, similar to those observed at lower energies for the scattering of halo nuclei. The overall structure of the cross-section is reasonably reproduced by the optical model calculations. The inelastic channels which populate two low-lying excited states of $^{12}\mathrm{C}$ target nucleus were included in the framework of the coupled channel analysis. Further systematic theoretical analysis is encouraged.

The first spectroscopic study for the beta decay of N-21 is carried out based on beta-n, beta-gamma, and beta-n-gamma coincidence measurements. The neutron-rich N-21 nuclei are produced by the fragmentation of the E/A=68.8 MeV Mg-26 primary beam on a thick Be-9 target and are implanted into a thin plastic scintillator that also plays the role of beta detector. The time of flight of the emitted neutrons following the beta decay are measured by the surrounding neutron sphere and neutron wall arrays. In addition, four clover germanium detectors are used to detect the beta-delayed gamma rays. Thirteen new beta-delayed neutron groups are observed with a total branching ratio of 90.5 +/- 4.2%. The half-life for the beta decay of N-21 is determined to be 82.9 +/- 7.5 ms. The level scheme of O-21 is deduced up to about 9 MeV excitation energy. The experimental results for the beta decay of N-21 are compared to the shell-model calculations.

A new transition is reported in the beta-delayed neutron decay of {sup 18}N. The observed neutron energy is 3.78{+-}0.05 MeV with a branching ratio of 0.05{+-}0.03%, which corresponds to an excitation energy of 12.05{+-}0.05 MeV in the daughter nucleus {sup 18}O. The log ft value of this transition is 5.24{+-}0.3, which, together with the previously reported electron scattering data, determines the J{sup {pi}} value of this level to be 1{sup -}. The experimental data are compared to the shell model calculations in different model spaces.

Breakup reactions of the double borromean nucleus 8He were measured at 82.3 MeV/u on CH2 and C targets. The coincident detection of two decaying neutrons and the high performance for neutron cross talk rejection are realized in this experiment. The relative energy spectrum for 8He was reconstructed with good statistics. The spectrum exhibits a structure of two resonant peaks, one at an excitation energy of about 3.0 and the other at about 4.14 MeV, respectively. Substantially larger cross section for the first resonance is observed in comparison to the results reported previously.