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This study evaluated whether the lactic acid bacteriaLactococcus lactissubsp.cremorisstrain FC (FC) could ameliorate host defenses and cognitive ability and extend the lifespan ofCaenorhabditis elegans, a model of senescence. The lifespan and resistance to physical, chemical, and biological stressors were compared betweenC. elegansfed FC and those fedEscherichia coliOP50 (OP), an international standard food forC. elegans. Living FC successfully extended the health span, enhanced host defense, and ameliorated the cognitive ability of the nematodes; even the exopolysaccharides (EPSes) of FC could extend the lifespan ofC. elegans. The chemotaxis index, which was used to evaluate the senescence of sensory neurons, tended to decrease with aging; however, it was more stable in worms fed FC and was significantly higher than that of the control worms at 7 days of age. The worms fed FC were tolerant toSalmonella entericaserovar Enteritidis orStaphylococcus aureusinfection and had better survival than the control worms fed OP. FC showed beneficial effects inC. elegans daf-16andpmk-1mutants, but not inskn-1mutants. Since SKN-1 is theC. elegansortholog of Nrf2, we measured the transcription of heme oxygenase-1 (HO-1), which is regulated by Nrf2, in murine macrophages and found that HO-1 mRNA expression was increased >5 times by inoculation with either FC cells or heat-killed bacteria with EPSes. Thus, both FC and the EPSes can affect longevityviathe SKN-1/Nrf2 pathway in both nematodes and mammalian cells.IMPORTANCEAgeing is one of our greatest challenges. The World Health Organization proposed the concept of “Active Ageing” might encourage people to continue to work according to their capacities and preferences as they grow old and would prevent or delay disabilities and chronic diseases that are costly to both individuals and the society, considering that disease prevention is more economical than treatment. Probiotic bacteria such as lactobacilli are living microorganisms that exert beneficial effects on human health when ingested in sufficient amounts and can promote longevity. The significance of this study is that it revealed the anti-senescence and various beneficial effects of the probiotic representative bacteriumLactococcus lactissubsp.cremorisstrain FC and its exopolysaccharides in the nematodeCaenorhabditis elegans.

6459 LNCS Sponsors: Game Research for Training and Entertainment (GATE) Conference code: 82783

A new velocity measurement system was developed and applied for the fullscale ship wake measurement. In this system, time history of space coordinates of a tracer is measured by three TV cameras, a video system, an image processor and a personal computer

Dalam kehidupan masyarakat seni sudah menjadi salah satu ciri khas yang tumbuh dan berkembang ditengah-tengah kehidupan masyarakat untuk mempertahankan sebuah kebudayaan Oleh karena itu diperlukan menumbuh kembangkan budayamembentukkomunitas.Permasalahan yang diangkat dalam skripsi ini adalah bagaimanakah analisis ritme dan melodi musik Calempong (lagu tingkah 9) di Kecamatan Bangkinang Kota Kabupaten Kampar Provinsi Riau. Penelitian ini bertujuan untuk mengetahui bentuk musik Calempong (lagu Tingkah 9) di Kecamatan Bangkinang Kota Kabupaten Kampar Provinsi Riau.Teori yang digunakanteori dan metode dalam etnomusikologi yaitu teori BrunoNettle (1964), dan teori ilmu bentuk musikyaitu teori Prier-Edmund Karl SJ(1996) dan Prier-Edmund Karl SJ(2004).Metodologi penelitian dalam penelitian adalah kualitatif interaktif, sedangkan teknik pengambilan data digunakan teknik observasi, dokumentasi, dan wawancara. Hasil penelitian diperoleh berdasarkan data deskriptif.Populasi pada penelitian ini yaitu musisi senior di Kecamatan Bangkinang Kota yang berjumlah 5 orang.Dalam penelitian ini peneliti menggunankan sampel pada penelitian ini menggunakan sampel purposive sample karena penulis hanya mengambil sampel diantara populasi.Metode ini bertujuan untuk mengetahui bentuk musik Calempong (lagu Tingkah 9) di Kecamatan Bangkinang Kota Kabupaten Kampar Provinsi Riau.Hasil penelitian dalam penelitian ini menunjukkan bahwa, ada lima hasil penelitian yaitu,1) Interval nada pada instrumen Calempong dan Gong, 2) Sistem notasi musik Calemponglagu Tingkah 9, 3)Gerak melodi lagu Tingkah 9, 4) Frase Melodi lagu Tingkah 9, 5)Pola ritem pada lagu tingkah 9, 6) Struktur komposisi lagu Tingkah 9 dan tempo lagu Tingkah 9. Kata Kunci : Analisi Musik Calempong ( Lagu Tingkah 9 ).