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Additional file 1.

Additional file 1: Table S1. Adjuvant treatments according to HER2 status within hormone receptor-positive and triple-negative breast cancer.

Additional file 4: Figure S2. Forest plot with hazard ratio showing BCSS according to HER2 IHC score in hormone receptor-positive breast cancer (A) and in triple-negative breast cancer (B).

Additional file 1: Supplementary information file. Fig. S1. MS and MS/MS spectra of authentic compounds of colistin. Fig. S2. MS and MS/MS spectra of colistin metabolites. Fig. S3. Comparison of MS and MS/MS fragmentation spectra between metabolite 3 produced by strain Col1 (a) and the chemically synthesized compound of cyclic peptide (b). Fig. S4. Growth and colistin-degrading activity of S. maltophilia strains Col1 (a), Col2 (b), and Col3 (c). Fig. S5. Colistin exposure protection to A. baumannii provided by Cdp-producing S. maltophilia strains. Fig. S6. Phylogeny of Cdp and its orthologous proteins representing colistin-degrading activity and colistin exposure protection. Table S1. Oligonucleotide primers used in this study.

Additional file 2: Figure S1. A Plasma clozapine concentration 10 days after clozapine pellet injection. Placebo-injected age-matched mice were used as controls (Student t test, ** p

Additional file 1: Supplementary information file. Figures S1. Correlations of ARG density with microbiological, genetic, physicochemical, geographic, and socio-economic parameters. Figure S2. Proportions of losses and gains of ARGs and OTUs between river samples according to geographic distance. Figure S3. Relative abundances of mobile genetic elements (MGEs) in the metagenome contigs of Han River. Figure S4. Co-occurrence of ARGs and MGEs in metagenome contigs. Figure S5. Horizontal gene transfer networks of ARGs inferred from pathogen genomes and river metagenomes. Figure S6. Comparison of ARG compositions between river and human gut metagenomes. Table S1. Sample metadata. Table S2. Representative fecal OTUs selected from the OTU table of the Earth Microbiome Project.

Additional file 1. Raw data of the tested parameters in wild-type.

This study evaluated the feasibility of recovering and recycling nitrogen (N) and phosphorus (P) from livestock excreta as struvite ( $MgNH_4PO_4{\cdot}6H_2O$ ) in South Korea. Our experimental results showed that struvite precipitation was a very effective way to recover N and P from livestock ex...

A 59-year-old man presented with recent onset jaundice. Initial laboratory and radiologic findings suggested autoimmune pancreatitis (AIP) with consequent obstructive jaundice. All serologic markers for AIP were, however, normal. To confirm the histologic finding of AIP and exclude the possibility of cancer at the thickened segment of common bile duct, cholangioscopic examination was performed and bile duct cancer was observed. The resected specimen showed typical features of AIP throughout the entire pancreas and early carcinomatous change on a background of abundant IgG4-positive cells in the common bile duct. Although chronic biliary inflammation and cholestasis are among bile duct cancer risk factors, the cause-and-effect relationship between sclerosing cholangitis and bile duct cancer needs to be determined by further study, as between AIP and pancreatic cancer. Importantly, histologic exclusion of malignancy is another essential step in the diagnosis of AIP and sclerosing cholangitis as malignancy may coexist in bile duct as well as in the pancreas.