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Additional file 1: Fig. S1. LSD1 is induced in a cellular model of ALS (N2a cell line). A, LSD1 immunoreactivity (red) was increased in the nucleus of mSOD1 (G85R) N2a cell line. The nucleus was counterstained with DAPI (blue). B, The densitometry analysis shows that LSD1 was significantly increased in G85R N2a cells. The number of cell counting: 35 cells/group. C, Western blot analysis shows that LSD1 protein level was highly induced in mSOD1 (G85R) N2a cell line compared to normal and WT-SOD1 overexpression cell lines. D, Densitometry analysis indicated a significant increase of LSD1 protein level in mSOD1 (G85R) N2a cells. Significantly different at *p < 0.05, ** p < 0.01, and ***p < 0.001. Fig. S2. Antioxidant modulates oxidative stress-induced LSD1-H3K4me2 pathway in a cell line model of ALS. A, A scheme illustrating procedure of cell experiment. B, Western blot analysis showed decrease of LSD1 and elevation of H3K4me2 by antioxidant (deferoxamine: DFO) in hydrogen peroxide (H2O2)-treated NSC-34/mSDO1 cells. C, Densitometry analysis of LSD1 and H3K4m2 levels from Western blot analysis (originated from B). D, Western blot analysis showed the LSD1 and H3K4me2 level maintained by DFO in H2O2-treated NSC-34/WT-SDO1 cells. E, Densitometry analysis of LSD1 and H3K4m2 levels from Western blot analysis (originated from D). F, Western blot analysis confirmed that DFO elevated the level of H3K4me2 in H2O2-treated NSC-34 motor neuronal cells.G, Densitometry analysis of LSD1 and H3K4m2 levels from Western blot analysis (originated from F). LSD1 and H3K4me2 were normalized to actin and histone H3 (H3), respectively. Significantly different at *p < 0.05 and **p < 0.01.

It is very important to develop a web-based education program to promote sexual and reproductive health (SRH) of immigrant women. This scoping review reviews the literature on the web-based education program for SRH promotion of immigrant women and intends to provide basic data for more advanced program development in the future. In this review, we will consider a web-based SRH education program for adult immigrant women in the community. We will also focus on the evaluation of the characteristics of the developed program, strategies, and outcomes. In order to show more forward-looking results, we will add data extraction according to the MISP standard and Kirkpatric level. The result present in a table, and summarize them in a narrative form. It is expected to provide useful information for the web-based educational programs to meet the various areas of MISP and to develop various program evaluation methods.

본 연구는 도시재생-복지관 협력사업의 참여경험을 바탕으로 주민들이 공동체적 주체성을 형성하는 과정과 다양한 주체의 상호작용을 탐색하여 ‘도시재생기반의 주민조직화 사업’에 대한 의미를 연구하였다. 질적연구방법에 따라 주민, 실천가를 심층면접 하여 분석한 현장연구이다. 분석결과, 도시재생 기반의 주민조직화 사업을 통해 주민들은 공동 과업의 성공경험을 공유하며 집단정체성을 형성하고 삶터에서 자생적 안전망의 기틀을 마련하는 것으로 나타났다. 이를 통해 본 사업은 ‘지역공동체복원’이라는 대안적 도시정책과정을 주민 친화적으로 추동시키는 주요 전략임을 확인했다. 연구 결과를 기반으로 복지관은 도시재생의 협력자로서 지역신뢰기반구축과 주민옹호에 집중해야 하며 도시재생의 주요한 실행 주체로서 고려되어야 함을 제언했다.

Even though norm-based filter pruning methods are widely accepted, it is questionable whether the "smaller-norm-less-important" criterion is optimal in determining filters to prune. Especially when we can keep only a small fraction of the original filters, it is more crucial to choose the filters that can best represent the whole filters regardless of norm values. Our novel pruning method entitled "REPrune" addresses this problem by selecting representative filters via clustering. By selecting one filter from a cluster of similar filters and avoiding selecting adjacent large filters, REPrune can achieve a better compression rate with similar accuracy. Our method also recovers the accuracy more rapidly and requires a smaller shift of filters during fine-tuning. Empirically, REPrune reduces more than 49% FLOPs, with 0.53% accuracy gain on ResNet-110 for CIFAR-10. Also, REPrune reduces more than 41.8% FLOPs with 1.67% Top-1 validation loss on ResNet-18 for ImageNet., Comment: Under Review at ECCV 2020