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Diabetes mellitus (DM) remains a concern globally and particularly in Saudi Arabia, where its prevalence is continuously increasing among the Saudi population. DM is known to increase the risk of cardiovascular disease (CVD), which can progress significantly if DM is poorly controlled.Determine the prevalence of cardiovascular events among patients with type 2 diabetes (T2DM) in the west region of Saudi Arabia, and additionally the use of antidiabetic agents with cardiovascular benefits (ADc) in T2DM patients with cardiovascular events (CVEs).A retrospective cohort study was conducted among all patients with T2DM who presented to the diabetic center of Prince Mansour Military Hospital (PMMH), Taif city, between the 1st of January and 30th of June 2021. Data extracted from patient medical records included demographics, home medications, medications used to treat T2DM, lab results, and ECG data. Descriptive statistics were used to analyze and compare the results. The study was approved by the Research and Ethics Committee of Medical Services General Directorate, Armed Forces Hospitals, Taif region.A total of 349 patients with T2DM were recruited and included in the final analysis. Of this study population, 132 patients had experienced at least one cardiovascular event while 54 were considered to be at risk of future cardiovascular events due to having risk factors for cardiovascular diseases above and beyond the presence of diabetes. A subgroup analysis was conducted to examine HbA1c% among all groups; interestingly, all were similar, withThe prevalence of CVEs among T2DM patients in Saudi Arabia is very close to the global prevalence, but ADcs are underutilized in this population. Tighter glycemic control is warranted to help rein in and reduce the CVE incidence among patients with T2DM.

Yousef E Alsaedi,1 Asim A Almalki,2 Rakan D Alqurashi,2 Rami S Altwairqi,3 Daifallah M Almalki,3 Khalid M Alshehri,3 Abdullah A Alamri,4 Khaled A Alswat5 1Public Health Department, Madinah Health Cluster, Madinah, Saudi Arabia; 2School of Medicine, Taif University, Taif, Saudi Arabia; 3Diabetes and Endocrine Specialist Center, Prince Mansour Military Hospital, Taif, Saudi Arabia; 4Endocrinology Department, Alhada Armed Forces Hospital, Taif, Saudi Arabia; 5Department of Medicine, School of Medicine, Taif University, Taif, Saudi ArabiaCorrespondence: Yousef E Alsaedi, Public Health Department, Madinah Health Cluster, P.O. Box 8592, Madinah, 42391, Saudi Arabia, Tel +966597181795, Email dr.y.alsa3di@gmail.comBackground: Diabetes mellitus type II (T2D) is a chronic condition that requires significant change in the family behavior and is associated with psychosocial conflicts for both patients and their family environment. The aim of this study is to assess burnout among relatives caring for patients with T2D.Methods: This cross-sectional study with random sampling was conducted on 501 caregivers of patients with T2D between April and September 2021 at Prince Mansour armed forces hospital in Taif city, Saudi Arabia. Data collection tool was a modified version of the caregiver stress self-assessment questionnaire. Data analysis was then carried out using t-test and chi-square test (SPSS v20).Results: The mean patient age was 64.4+12.0 years, female predominant with longstanding T2D. Metformin was the most prescribed T2D medication. The caregivers’ mean age was 34.9+12.4 years, male predominant, and around 45% of them report low level of education and income; 63.9% of the caregivers report little to no stress. Compared with caregivers with mild/moderate stress and moderate/severe stress, caregivers with little to no stress were more likely to be younger in age (P < 0.001), male (P = 0.464), single (P = 0.035), patient’s offspring (P = 0.490), caring for T2D patients with younger age (P = 0.058) and shorter T2D duration (P = 0.074), patients who were less likely to use a wheelchair (P = 0.008), patients who were less likely to be prescribed a complex insulin regimen and with better glycemic control parameters (both P > 0.05), and patients with higher HDL level (P = 0.037).Conclusion: There were no correlations between the caregivers’ levels of stress and the T2D patients’ HbA1c levels. There was a significant positive correlation between a caregiver’s stress score and the caregiver’s age. Future studies are needed to assess other caregivers’ parameters and their relation to metabolic control of T2D patients.Keywords: diabetes, burnout, caregiver

Post inflammatory hyperpigmentation (PIH) can affect people of all skin colours, but it is more common in people of colour, such as African Americans, Hispanics/Latinos, Asians, Native Americans, Pacific Islanders, and those of Middle Eastern descent. There is no distinction between men and women. In darker-skinned acne sufferers, the prevalence of PIH might reach 65 percent. Many studies have demonstrated that topical retinoids, especially in darker skin types, can be beneficial in treating PIH associated with acne. However, Hydroquinone is still a go-to treatment for melasma and hyperpigmentation, and it's commonly referred to as the "gold standard." triple combination fixed treatment has also become a common intervention, with evidence showing that the combination is more successful than hydroquinone monotherapy. In this review article we will be looking at PIH etiology, epidemiology, different treatment options as well as the effectiveness of each medication.

Background: Obesity-related morbidity continues to increase in Saudi Arabia, especially among school students, who constitute a vulnerable population since they can be highly influenced by the western culture and rapid globalization. Aim of Study: To examine the relationship between obesity and negative emotional states among male secondary school students. Methodology: This was a cross-sectional study conducted among male secondary school students in Abha City, Saudi Arabia during the academic year 2019-2020. A multistage cluster sampling technique was followed by the researchers, in order to recruit participants. The standardized Arabic version of Depression Anxiety Stress Scale (DASS-21) was used by the researchers for determining prevalence and levels of depression, anxiety and stress symptoms among participants. Results: Three hundred and ninety eight students participated in the study. Their mean age (±SD) was 16.98±0.93 years. Overweight and obesity was present among 44.2% and 38.4% of participants respectively. The overall prevalence rates for symptoms of depression, anxiety and stress among participants were 57%, 64.6% and 39.4%, respectively. There were statistically significant associations between obesity and symptoms of depression, anxiety and stress (p

Peripheral neuropathy is a common diabetic complication. It is linked to poor glycaemic control and longer duration of diabetes. We explored the association between HbA1c and neuropathy risk considering the duration of diabetes in a sample of Saudi diabetic patients.We conducted a monofilament test on 343 diabetic patients referred to our specialist diabetology centre in Saudi Arabia. We utilized a multiple generalized logistic regression model with a binary outcome related to neuropathy complications.We found that over four out of every five patients have peripheral neuropathy. The interaction between HbA1c and duration was significant (estimate = -0.02802,The shorter the duration of diabetes, the more positive the relationship between HbA1c and peripheral neuropathy. In patients living for over 40 years with diabetes, HbA1c was higher among those who did not have peripheral neuropathy. It could be argued that this is an artefact of survival as poorer glycaemic control will likely result in higher mortality in earlier years of the diabetes career.