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Newborn ungulates depend on the timely supply of colostrum containing sufficient immunoglobulins to obtain passive immunity against disease. Brix refractometry enables a rapid on-farm estimation of colostrum quality and has been intensively studied in bovines. However, the suitability of Brix refractometers for assessing colostrum quality in goats and ewes has been scarcely evaluated. The present study compared bovine, caprine, and ovine colostrum quality estimation using an optical Brix refractometer. In addition, between-species variations in the relationships between Brix values and colostrum constituents (IgG, fat, protein, and lactose) and the accuracy of Brix refractometry at different cutoff values were evaluated by a receiver operating characteristic curve analysis. We measured the Brix value and contents of IgG, fat, protein, and lactose in 324 colostrum samples (108 cows, 116 does, and 100 ewes). Thresholds for classification of good colostrum quality (as determined by ELISA) were set at 50 mg IgG/mL in cows and 20 mg/mL in does and ewes. Bovine colostrum showed the greatest IgG concentrations compared with caprine and ovine colostrum. Fat and protein content was higher in sheep colostrum compared with the other species, whereas the highest lactose concentrations were detected in goat colostrum. Brix values ranged from 11.4 to 34.6% (22.1 ± 4.2%; mean ± standard deviation), 15.4 to 40.0% (28.5 ± 6.8%), and 8.8 to 39.8% (21.6 ± 5.3%) in bovine, ovine, and caprine colostrum, respectively. In all 3 species, Brix was highly correlated with IgG and protein concentrations (cows, r = 0.83 and 0.98; goats, r = 0.83 and 0.89; sheep, r = 0.75 and 0.87). Optimal cutoff points for greatest accuracy of Brix measurements were 19.3% Brix in cows [with 87.1% sensitivity (Se) and 100% specificity (Sp)], 20.7% Brix in does (with 53.5% Se and 100% Sp), and 26.5% Brix in ewes (with 75% Se and 91.3% Sp). In conclusion, Brix refractometry is an acceptable tool for on-farm estimations of colostrum quality in does and ewes despite distinct between-species variations in colostrum composition.

We report on a new case of duplication of the proximal part of the long arm of chromosome 21. The proposita presents normal mental development, no trisomy 21 manifestations; on the contrary, she had a few monosomy 21-like stigmata. She gave birth to a severely malformed infant with a pattern of malformations suggesting a partial 21-monosomy syndrome, but with a 46,XY normal karyotype in his peripheral blood lymphocytes. The findings are explained in the following way: the infant probably had originally a 47,XY, + 21q – karyotype like his mother. Post zygotic nondisjunctional events produced a prevalent 46,XY,21q – line responsible for the severe malformations and the normal 46,XY line found in his blood lymphocytes.

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Integrating a thermopile with a low power operational amplifier is an effective and cost-efficient approach to obtain a high performance compact Terahertz power detector. Here we present the development of such an integrated detector, including the fundamental building blocks, the final realization and related characterization. The responsivity and bandwidth of the detector are measured in a standard THz CW setup consisting of a closed cycle helium cryostat and a Quantum Cascade Laser (QCL). The predicted results are compared with measured data, showing a good agreement. Advantages of existing Golay cell THz detectors in both sensitivity and NEP figure vanish, in practical use, due to the enormous increment in dynamic range provided by the linear operation of the thermopile up to 100 mW of incident power while offering a NEP below 1nW/sqrt(Hz) and a -3dB bandwidth of 6,8 Hz., Comment: 6 pages, 9 pictures, distilled with AFPL Ghostscript 7.04

A method for stabilization of flail chest is described. A row of pericostal chromic catgut sutures is placed from the pleural surface using a probe as ligature carrier.

Neben den mesenterialen Gefasen kommt der Peritonealfliissigkeit eine entscheidende Rolle in der Ernahrung der Darmwand zu. Der freie Kontakt mit der Peritonealfliissigkeit erh6ht die Ischamietoleranz der Darmwand um 100%.