1. Endothelial Cell Loss in Corneal Grafts From Donors Who Sustained Gunshot Wound to the Head or Airbag Deployment in a Motor Vehicle Accident
- Author
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Palioura, Sotiria Vingopoulos, Filippos Likht, Nikita Piedra, Cristissa M. Fout-Caraza, Elizabeth Dubovy, Sander R. Karp, Carol L.
- Subjects
surgical procedures, operative ,genetic structures - Abstract
PURPOSE: To compare the endothelial cell density (ECD) and quality of corneal grafts from young donors who sustained airbag deployment in motor vehicle accidents (MVA) or gunshot wounds (GSW) to the head with grafts from donors of similar age who died of other causes. METHODS: This is a retrospective comparative series of 65 corneal grafts from 33 young donors (mean age, 29.60 ± 8.95 yrs), with the cause of death either MVA with airbag deployment (n = 7), GSW to the head (n = 14), or other nontrauma-related cause (n = 12). Donor characteristics, graft quality on slit-lamp examination, ECD, and areas of endothelial cell loss on specular microscopy were compared between the groups. RESULTS: Donor age, graft quality on slit-lamp examination, and death-to-preservation time were similar between the groups. Statistically significant differences in focal areas of endothelial cell loss were found in the MVA- and GSW-derived grafts compared with the nontrauma-related grafts (85.7% vs. 0%, P value 0.0002 and 92.5% vs. 0%, P value
- Published
- 2020