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Preregistration of analyses related to HCPs’ attitudes to Covid-19 mandates (JITSUVAX WP1)

Preregistration of a data collection related to a study on vaccine confidence among healthcare professionals. Five countries participate in the study: France, UK, Germany, Portugal, and Finland. The present preregistration concerns the data collection carried out in Finland.

This is a pre-registration of the hypotheses and method prior to data collection.

Additional file 4: Supplementary Table 4. Multicentre studies on COVID-19 in patients with haematologic malignancies reported during 2020.

Additional file 1: Supplementary Table 1. Partnership from National and International Scientific Society.

Additional file 2: Supplementary Table 2. List of participating institutions.

Additional file 3: Supplementary Table 3. Demographic and clinical characteristics of enrolled patients depending on the COVID-19 severity.

Previous research on how stereotypes affect perceptions of intimate partner violence and domestic homicide has found that violence committed by men is perceived as more severe and judged more harshly than violence committed by women. The present mock jury study investigated how perpetrator sex (male or female), crime type (familicide or filicide), and relatedness between perpetrator and child victims (biological or step) affect laypeople’s perceptions of the appropriate consequence of the crime, the reason for the offence, responsibility of the perpetrator, the likelihood of certain background factors being present, and the risk of future violence. One hundred sixty-seven university students read eight fictive descriptions of cases of multiple-victim domestic homicides, in which the sex of the perpetrator, the crime type, and the relatedness between the perpetrator and the child victims were manipulated. We found that participants recommended equally severe punishments to and placed the same amount of responsibility on male and female offenders. Female offenders were, however, regarded as mentally ill to a larger extent and perceived more likely to have been victims of domestic violence compared to male offenders. Male offenders, on the other hand, were seen as more likely to have committed domestic violence in the past, having been unemployed, have substance abuse, hold aggressive attitudes, and commit violent acts in the future. Participants also perceived offenders killing biological children as more mentally ill than offenders killing stepchildren. The present study extends the literature on the possible effect of stereotypes on decision making in psychiatric and judicial contexts.

QR ADPKD Additional Questions 20140205 Eng.pdf â Self-administered questionnaire â Questionnaire administered to patients. (PDF 16Â kb)

QR ADPKD CRF 20140331 Final v1.1.pdf – Case report form (CRF) – Questionnaire used to collect data from patients’ medical charts. (PDF 624 kb)

Increasing the use of locally produced protein feeds in ruminant production systems in northern Europe would be a valuable development. Hemp (Cannabis sativa L.) can be cultivated at high latitudes and cold-pressing the seeds to extract the oil produces a residue, hempseed cake (HC), with a high protein content. The overall aim of the studies presented in this thesis was to investigate the possibilities of using HC as a protein feed for ruminants. The in vitro gas production technique was developed further in order to estimate rumen protein degradation; the effective protein degradation (EPD) of HC determined by this method was low (0.33). When calculated from in situ crude protein (CP) disappearance, HC had a high EPD value (0.71-0.84) and a low in vitro intestinal digestibility (0.18-0.31) for the rumen undegradable protein (RUP). Moist heat treatment could be used to shift the site of CP digestion from the rumen to the small intestine. The highest temperature considered, 130°C, was associated with the largest amount of RUP and rumen undegraded amino acids with the highest intestinal digestibility. A high proportion of the neutral detergent fibre in HC was indigestible (0.85), which contributed to a low calculated metabolisable energy value (9.5 MJ/kg dry matter). Increasing the proportion of HC (0, 143, 233 or 318 g/kg dry matter) in the diet of dairy cows produced effects on the yields of milk, energy corrected milk and milk protein, fat and lactose that could be described by quadratic functions; the highest production was achieved by cows fed the diet containing 143 g HC/kg dry matter. There were linear decreases in the concentration of milk fat and protein and CP efficiency (milk protein/CP intake), and a linear increase in milk urea, with increasing proportions of HC. Supplementing barley-based diets with peas or rapeseed cake improved the growth performance of lambs, but inclusion of HC resulted in an average daily gain similar to that achieved with the control diet containing no protein supplement. The results from the studies underlying this thesis indicate that the nutritional value of HC will limit its use as a protein feed for ruminants.

En omfattande studie för att jämföra ekologisk odling och mjölkproduktion med konventionell, genomfördes på Öjebyns försöksstation, Institutionen för norrländsk jordbruksvetenskap, SLU, under åren 1990-2001. Resultaten från Öjebynprojektet visar på mycket goda ekologiska produktionsresultat. Det råder dock tvivel om forskningsresultaten kan omsättas på kommersiella gårdar. Syftet med den här studien är att jämföra resultaten från den ekologiska produktionen i Öjebynprojektet med kommersiella jordbrukares resultat och på så sätt finna de ”flaskhalsar” och svårigheter som lantbrukare ställs inför vid ekologisk mjölkproduktion i norra Sverige. Sex ekologiska gårdar i norra Sverige deltog i dokumentationsprojektet som pågick under fyra år, 2003-2006. Gårdarna hade i genomsnitt 37 kor och en odlad areal på 78 ha. Under projektet samlades gårdsdata rörande besättningsresultat, utfodring, tillväxt på ungdjur, skördenivåer och vallarnas botaniska sammansättning. Även markkarteringar, växtnäringsbalanser, foderstatskontroller och foderanalyser har dokumenterats. Väderstatistik hämtades från SMHI. En enkel kalkyl upprättades för att jämföra det ekonomiska resultatet i den ekologiska vallodlingen mellan dokumentationsprojektet och Öjebynprojektet. Lantbrukarna fick också svara på ett antal frågor om framtiden som ekologiska producenter. Den genomsnittliga avkastningen på vall I-III var 4250 kg ts/ha. Skördenivåerna på äldre vallar var lägre, i genomsnitt 3085 kg ts/ha. Insåningsgrödans medelavkastning va 3187 kg ts/ha. Avkastningarna var betydligt lägre än vad som uppmättes i den ekologiska växtodlingen under Öjebynprojektet. Andelen baljväxter i vallarna sjönk med ökad vallålder, genomsnittet låg på 24 procent. Ogräsandelen var i medeltal 16 procent. De ekologiska vallarna i Öjebynprojektet hade en högre baljväxtandel och en lägre andel ogräs. Växtnäringsbalanserna visar att gårdarna i genomsnitt hade ett överskott av näringsämnen på 77 kg N/ha, 4 kg P/ha och 14 kg K/ha. Detta överskott var högre än vad som observerades för det ekologiska produktionssystemet i Öjebynprojektet. Medelavkastningen låg på 8845 kg ECM/ko/år vilket var högre än den genomsnittliga ekologiska mjölkavkastningen under Öjebynprojektet. Genomförda foderstatskontroller på gårdarna visar att den utfodrade mängden grovfoder var större än uppgifterna i IndividRAM. Tillväxten på ungdjuren var i genomsnitt 590 g/dag under stallperioden och 648 g/dag under betesperioden. Kalkylen för beräkning av priset på ensilage visar att den högre avkastningen på Öjebyns ekologiska vallar ledde till en lägre produktionskostnad, 0,67 kr/kg TS jämfört med 0,93 kr/kg TS för projektgårdarna. Resultaten från detta dokumentationsprojekt visar att det finns en relativt stor förbättringspotential i växtodlingen på de studerade gårdarna. Den högre andelen ogräs och den lägre andelen klöver har troligen bidragit till de betydligt lägre avkastningsnivåerna på projektgårdarnas vallar, jämfört med Öjebynprojektets ekologiska vallar. Den högre ogräsandelen kan vara kopplad till val av insåningsgröda, vilken har skiljt sig åt mellan Öjebynprojektet och de studerade gårdarna. En intensivare vallodling där en växtföljd med kortliggande vallar tillämpas förbättrar chanserna att öka hektarskörden och på så sätt producera ett billigare grovfoder.

The formation of organs during embryonic development is calledorganogenesis. This process is regulated by the genes residing in the genome.Thousands of genes are likely to be involved, but there are increasing evidence thatmost organs develop through similar processes performed by conserved networks ofgene products from the same multi-gene families.Platelet-derived growth factor-A (PDGF-A) is a classical growth factor thatexerts its function via a receptor tyrosine kinase, PDGF receptor-á (PDGFR-á). Micedeficient for PDGF-A and PDGFR-á have been analysed in order to elucidate thefunction of PDGF-A in vivo. Deletion of either gene leads to perturbed developmentof several organ systems.In the central nervous system, PDGF-A is critical for the proliferation andspreading of oligodendrocyte progenitors. Loss of PDGF-A leads to defectiveoligodendrogenesis and hypomyelination.In the lung, PDGF-A is critical for multiplication and spreading ofmesenchymal alveolar smooth muscle cell progenitors along the branching bronchialtree. Loss of PDGF-A leads to loss of alveolar smooth muscle cells resulting in a lungdefect reminiscent of lung emphysema.In the skin, PDGF-A is proposed to promote proliferation of a subset ofPDGFR-á positive mesenchymal cells. These cells are subsequently recruited tobecome dermal fibroblasts and the mesenchymal components of the hair follicle: thedermal papilla and the dermal sheath. Lack of PDGF-A leads to fewer cells at theselocations, causing malformed hair follicles, thinner hair and failure to enter the secondhair cycle.A similar role is suggested for PDGF-A in the intestine. PDGF-A promotesproliferation of a subset of PDGFR-á positive mesenchymal progenitor cells that areinvolved in villus formation. At the onset of villus formation, these cells form clusters(called villus clusters) that remain localised at the tip of the growing villus. Our dataimplicate that the villus cluster is instrumental in villus morphogenesis. In the absenceof either PDGF-A or PDGFR-á , fewer villi are formed and those generated areabnormal in size and shape.In summary, we suggest that PDGF-A is a component in one of the conservedgene product networks, where the general principle for PDGF-A is to promoteproliferation (and possibly spreading at some locations) of progenitor cells thatsubsequently differentiate into cell types with important functions in organogenesis.In the lung, skin and hair follicles, and the gastrointestinal villus, the PDGF-A dependent cells are important in epithelial folding.

Supplemental Material, Table_S1 for Familicide: A Systematic Literature Review by Linda C. Karlsson, Jan Antfolk, Hanna Putkonen, Sabine Amon, João da Silva Guerreiro, Vivienne de Vogel, Sandra Flynn, and Ghitta Weizmann-Henelius in Trauma, Violence, & Abuse

Syftet med detta rundabordssamtal är att utbyta erfarenheter och diskutera hur olika stöd till doktoranders lärande samverkar under forskarutbildningens gång. Vilka pedagogiska utmaningar finns i att möta doktoranderna som individer i sitt avhandlingsprojekt men också i den större kontexten bestående av forskningsmiljön, disciplinen och doktorandkollektivet?

Additional file 1. Questionnaire in English

Supplemental Material, Table_S2_Cases for Familicide: A Systematic Literature Review by Linda C. Karlsson, Jan Antfolk, Hanna Putkonen, Sabine Amon, João da Silva Guerreiro, Vivienne de Vogel, Sandra Flynn, and Ghitta Weizmann-Henelius in Trauma, Violence, & Abuse

Supplemental Material, Table_S1 for Familicide: A Systematic Literature Review by Linda C. Karlsson, Jan Antfolk, Hanna Putkonen, Sabine Amon, João da Silva Guerreiro, Vivienne de Vogel, Sandra Flynn, and Ghitta Weizmann-Henelius in Trauma, Violence, & Abuse

Supplemental Material, Table_S1 for Familicide: A Systematic Literature Review by Linda C. Karlsson, Jan Antfolk, Hanna Putkonen, Sabine Amon, João da Silva Guerreiro, Vivienne de Vogel, Sandra Flynn, and Ghitta Weizmann-Henelius in Trauma, Violence, & Abuse

Additional file 1. Questionnaire in English

Supplemental Material, Table_S2_Cases for Familicide: A Systematic Literature Review by Linda C. Karlsson, Jan Antfolk, Hanna Putkonen, Sabine Amon, João da Silva Guerreiro, Vivienne de Vogel, Sandra Flynn, and Ghitta Weizmann-Henelius in Trauma, Violence, & Abuse

Supplemental Material, Table_S2_Cases for Familicide: A Systematic Literature Review by Linda C. Karlsson, Jan Antfolk, Hanna Putkonen, Sabine Amon, João da Silva Guerreiro, Vivienne de Vogel, Sandra Flynn, and Ghitta Weizmann-Henelius in Trauma, Violence, & Abuse