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Supplemental material, sj-pdf-1-ajs-10.1177_03635465231152899 for The Associations Between Quadriceps Tendon Graft Thickness and Isokinetic Performance by Michael I. Letter, Rosalia L. Parrino, Will Adams, Zachary Ripic, Michael G. Baraga, Lee D. Kaplan, Tanner Harrah, Julien Tremblay, Dylan Luxenburg, Joseph Conti and Joseph F. Signorile in The American Journal of Sports Medicine

Additional file 3: Figure S3. Interactome of proteins significantly up-regulated in TI or TIC conditions. All secreted proteins appeared interconnected at least through one association (except PIGF when present) and the K-means clustering networks demonstrated elevated protein-protein interaction (PPI) enrichment (p-value 0.7 indicating that the proteins used are at least partially biologically connected. (A) In TI-induced IFP-MSC spheroids all subpopulation cohorts revealed overall similar biological processes. Crude TI-induced cohort showed higher involvement in all tested biological processes except positive regulation of cell population proliferation and angiogenesis, which showed significantly higher involvement in TI-induced CD146POS cohort (5.5% and 16.5% higher respectively) (Supplementary Figure 2A, left radar graph). (B) In TIC-induced IFP-MSC spheroids, Crude cohort showed higher involvement in 4 out of 7 biological processes tested. Compared to TI induction, TIC induction significantly decreased the angiogenesis biological process involvement in crude cohort (from 14 to 0%) and significantly increased its involvement in CD146POS cohort (from 30.7 to 41.7%) (A and B) Overall, in both TI- and TIC-induced IFP-MSC spheroids, CD146POS cohort showed significantly stronger protein involvement in 4 out of 8 KEGG reactome pathways (MAPK, PI3K-Akt, Ras, and Rap1 signaling pathways) compared to other cohorts.

Additional file 2: Figure S2. Tables show the number of proteins significantly different between the three different cohorts (Crude, CD146POS, CD146NEG) upon TI or TIC induction compared to non-induced cultures.

Additional file 1: Figure S1. Molecular evaluation of IFP-MSC. (A) CD146 protein expression levels were significantly (*p

Additional file 4: Table S1. Transcripts and primers.

Additional file 5: Table S2. Human mesenchymal stem cell qPCR array plate genes and their classification.

Supplemental Material, DS_10.1177_0363546520919989 for The Effect of Thursday Night Games on In-Game Injury Rates in the National Football League by Jose R. Perez, Jonathan Burke, Abdul K. Zalikha, Dhanur Damodar, Joseph S. Geller, Andrew N.L. Buskard, Lee D. Kaplan and Michael G. Baraga in The American Journal of Sports Medicine

Supplemental material, DS_10.1177_0363546520917699 for CD10/Neprilysin Enrichment in Infrapatellar Fat Pad–Derived Mesenchymal Stem Cells Under Regulatory-Compliant Conditions: Implications for Efficient Synovitis and Fat Pad Fibrosis Reversal by Dimitrios Kouroupis, Annie C. Bowles, Thomas M. Best, Lee D. Kaplan and Diego Correa in The American Journal of Sports Medicine