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Entrepreneurship is one of the growing trends, and studies are focusing on it generally. However, this study is mainly focused on women’s entrepreneurship. This study intends to measure the impact of work-family interference, socio-cultural support, access to finance entrepreneurial skills, and legal constraints on women’s entrepreneurial involvement through the mediation of self-leadership in the hospitality and tourism sector. This study has chosen a quantitative approach, collecting data through surveys. The snowball sampling method was used for data collection from women of Pakistan, and data was analyzed through the PLS-SEM method. The result of the present study affirms that work-family interference, social and cultural support, and entrepreneurial skills are significantly associated with women’s entrepreneurial involvement other than access to finance and legal constraints. Moreover, self-leadership significantly mediates between (work-family interference, socio-cultural support, and access to finance) and women’s entrepreneurial involvement except for entrepreneurial skills and legal constraints. The present study’s findings affirm that formal or informal institutions influence women’s entrepreneurial involvement. This study may help women entrepreneurs understand the factors and policymakers to make policies for women entrepreneurs in the hospitality sector.

DOI 10.17605/OSF.IO/JSUYB

Tuberculosis is one of the most important communicable diseases worldwide. Its Antituberculosis therapy (ATT) has multiple side effects, out of which ATT induced hepatitis is important one, as it can force the Physicians to modify the treatment. Objective: To determine the frequency of first line Anti Tuberculosis drugs induced hepatotoxicity during intensive phase of treatment. Subject and Methods: This was a descriptive case series study conducted at multicenter during July 2018 to December 2018. In this study, 150 patients of either gender with age range of 15 to 60 years were selected by non-probability consecutive sampling after fulfilling the inclusion and exclusion criteria. They were started on category 1 of ATT. They were then followed for two months for the development of ATT induced hepatitis, which was monitored with the help of clinical symptoms and liver enzymes. Results: In present study, there were total 150 cases out of which 80 were male and 70 females with mean age of 34.28± 15.28 years. There were 115 cases suffering from PTB and 35 from EPTB. ATT induced hepatotoxicity was found in 17 out of 150 patients (11.33%). Among these 17 hepatotoxic patients 10 were males and 7 were females (p=0.63). ATT induced hepatitis was more seen in cases of PTB where it occurred in 15 cases (p= 0.14) and among the PTB, the highest was seen in far advanced TB (47.8%), which was statistically significant (p = 0.026). Highest incidence of hepatotoxicity (22.5%) was found in age group of 49 to 60 years, which was statistically significant (p= 0.036). Majority (13 out of 17) developed it within first 30 days. Conclusion: ATT induced hepatitis is a common side effect. About one in every nine case develops it. Old age and Pulmonary disease, especially far advance disease is associated with higher risk of hepatotoxicity. Key Words: Tuberculosis, Hepatitis, First line ATT.