5 results on '"Jiao, Yanan"'
Search Results
2. The effect of Chaihu-shugan-san on cytotoxicity induction and PDGF gene expression in cervical cancer cell line HeLa in the presence of paclitaxel +cisplatin
- Author
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Zhu Ling, Jiao Yanan, Guan Yanliang, and Xue Jianfang
- Subjects
Time Factors ,Paclitaxel ,Cell Survival ,Uterine Cervical Neoplasms ,Antineoplastic Agents ,Metastasis ,HeLa ,chemistry.chemical_compound ,Gene expression ,medicine ,Humans ,Cytotoxicity ,Cisplatin ,Platelet-Derived Growth Factor ,biology ,Dose-Response Relationship, Drug ,Chemistry ,Plant Extracts ,Reverse Transcriptase Polymerase Chain Reaction ,Cancer ,General Medicine ,biology.organism_classification ,medicine.disease ,Gene Expression Regulation, Neoplastic ,biology.protein ,Cancer research ,Female ,Platelet-derived growth factor receptor ,medicine.drug ,Drugs, Chinese Herbal ,HeLa Cells - Abstract
Chaihu-shugan-san, as a traditional Chinese herbal formula, is composed of seven different herbs. This medicine can treat cancer due to its antioxidant compounds. In this study, the effect of Chaihu-shugan-san was considered on cytotoxicity induction and PDGF gene expression in cervical cancer cell line HeLa at different concentrations and at different times, by the MTT method. Paclitaxel + cisplatin were used as a control in this study. The expression of the PDGF gene was quantitatively evaluated in treated cells by real-time PCR, and a generalized linear model was used to evaluate the effect of the medicine, and Duncan's multiple range tests were used to evaluate the data. The results of the MTT test showed that Chaihu-shugan-san had antitumor properties in different concentrations, but there was a significant difference between this medicine and paclitaxel +cisplatin. Also, examination of gene expression showed that this medicine reduced the expression of the PDGF gene in the HeLa cancer cell line (P ? 0.04). Therefore, Chaihu-shugan-san could be suggested as an effective factor in preventing the growth of cervical cancer cells and controlling angiogenic factors that play an important role in the metastasis of cancerous tumors.
- Published
- 2021
3. Electronic nose sensors data feature mining: a synergetic strategy for the classification of beer
- Author
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Gong Furong, Hong Men, Jingjing Liu, Jiao Yanan, and Yan Shi
- Subjects
Electronic nose ,Computer science ,business.industry ,General Chemical Engineering ,010401 analytical chemistry ,Feature extraction ,General Engineering ,Pattern recognition ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Field (computer science) ,0104 chemical sciences ,Analytical Chemistry ,Support vector machine ,Set (abstract data type) ,Feature (computer vision) ,Pattern recognition (psychology) ,Artificial intelligence ,0210 nano-technology ,business ,Projection (set theory) - Abstract
The effective feature mining method is one of the key problems in the field of pattern recognition. Moreover, the lack of efficient feature extraction and selection methods has limited the application and development of electronic nose (e-nose) technology. In this study, a synergetic strategy for e-nose sensors data feature mining was proposed in combination with Support Vector Machine (SVM) to determine the beer olfactory information. First, twenty time-domain features and twenty frequency-domain features of e-nose sensors data were extracted to represent the olfactory characteristics of beer. Second, forty features were sorted with variable importance in projection (VIP) scores and forty subsets of multi-features with the best VIP score were generated. Finally, the classification models were established based on SVM, and the best parameter c and g of SVM models was calculated by Genetic Algorithm (GA). Furthermore, the classification performance of each class was evaluated by efficiency value (EFF) in different feature sets. The result indicates that GA-SVM model achieves good classification performance based on the #27 feature set with 81.67% and 96.67% in calibration set and testing set, respectively, and the EFF value is also the highest compared with other feature sets. In conclusion, it indicated that the analytical method can be used as a reliable tool for accurate identification of beer olfactory information.
- Published
- 2018
4. Odor Fingerprint Analysis Using Feature Mining Method Based on Olfactory Sensory Evaluation
- Author
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Yan Shi, Jingjing Liu, Gong Furong, Hong Men, Hairui Fang, Yizhou Chen, and Jiao Yanan
- Subjects
intelligent nose ,Computer science ,Sensory system ,feature mining method ,02 engineering and technology ,frequency domain ,lcsh:Chemical technology ,01 natural sciences ,Biochemistry ,Article ,Analytical Chemistry ,Probabilistic neural network ,Fingerprint ,Chinese liquor ,0202 electrical engineering, electronic engineering, information engineering ,Animals ,Humans ,lcsh:TP1-1185 ,Electrical and Electronic Engineering ,Instrumentation ,olfactory sensory evaluation ,Principal Component Analysis ,business.industry ,time domain ,010401 analytical chemistry ,Pattern recognition ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Random forest ,Odor ,Feature (computer vision) ,Alcohols ,Odorants ,Principal component analysis ,020201 artificial intelligence & image processing ,Neural Networks, Computer ,Artificial intelligence ,odor fingerprint analysis ,business - Abstract
In this paper, we aim to use odor fingerprint analysis to identify and detect various odors. We obtained the olfactory sensory evaluation of eight different brands of Chinese liquor by a lab-developed intelligent nose. From the respective combination of the time domain and frequency domain, we extract features to reflect the samples comprehensively. However, the extracted feature combined time domain and frequency domain will bring redundant information that affects performance. Therefore, we proposed data by Principal Component Analysis (PCA) and Variable Importance Projection (VIP) to delete redundant information to construct a more precise odor fingerprint. Then, Random Forest (RF) and Probabilistic Neural Network (PNN) were built based on the above. Results showed that the VIP-based models achieved better classification performance than PCA-based models. In addition, the peak performance (92.5%) of the VIP-RF model had a higher classification rate than the VIP-PNN model (90%). In conclusion, odor fingerprint analysis using a feature mining method based on the olfactory sensory evaluation can be applied to monitor product quality in the actual process of industrialization.
- Published
- 2018
5. Efficiency measurement of China commercial banks with comprehensive evaluation methodology
- Author
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Xie Limei and Jiao Yanan
- Subjects
Competition (economics) ,Hardware_MEMORYSTRUCTURES ,Actuarial science ,Economic indicator ,Evaluation methods ,Data envelopment analysis ,Resource management ,Business ,China ,Industrial organization - Abstract
Following the agreement on WTO, more and more foreign commercial banks have debuted into China bank industry since 2007. Currently, the domestic commercial banks in China will face especially more challenge and competition in their running. Efficiency of commercial banks is the main factor on reflecting the competition capability of banks. The comprehensive evaluation method, denoted as Data Envelopment Analysis, was applied to efficiency measurement of China commercial banks in this paper. By using the comprehensive evaluation results, the measurements for enhancing the efficiency of China commercial banks were drawn.
- Published
- 2010
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