Search

Objective: To study the effect of sal ammoniac extract on the treatment of liver cancer and analyze its possibility of replacing absolute ethanol. Methods: Sixty Kunming mice (5-6 weeks old, 18-22g in weight, male and female in half) were selected and inoculated with 0.1 ml of 1:4 ascitic diluent from mouse liver cancer H22 under the axilla of the right limb. After tumor formation, they were randomly divided into 3 groups with 20 mice in each group. Normal saline (NS), sal ammoniac extract (N), and absolute ethanol (E) were injected into the tumor once a day for four times. The death, tumor weight, tumor inhibition rate, lactate dehydrogenase (LDH), and succinate dehydrogenase (SDH) expression of the mice in each group were analyzed. Results: In the course of treatment, 3 mice died in the normal saline group, 2 mice died in the sal ammoniac treatment group, and 7 mice died in the absolute ethanol group. The tumor weight of the normal saline group, sal ammoniac treatment group, and absolute ethanol group were 1.88 ± 0.26, 1.41 ± 0.49, and 1.51 ± 0.46, respectively. The tumor inhibition rates were 0%, 31.0%, and 21.6%, respectively. Comparing the sal ammoniac treatment group and the normal saline group, t = 3.5133, p = 0.0013; comparing the absolute ethanol group and the normal saline group, t = 2.7926, p = 0.0093. The expression of LDH was 81 ± 10, 51 ± 11, and 32 ± 9 in the normal saline group, sal ammoniac treatment group, and absolute ethanol group, respectively, while the expression of SDH was 80 ± 10, 51 ± 10, and 51 ± 12 in the normal saline group, sal ammoniac treatment group, and absolute ethanol group, respectively. Comparing the LDH of the sal ammoniac treatment group with that of the saline group, t = 8.4264, p = 0.0000; comparing the absolute ethanol group and normal saline group, t = 13.8763, p = 0.0000. Comparing the SDH of the sal ammoniac treatment group with that of the normal saline group, t = 8.1455, p = 0.0000; comparing the absolute ethanol group with the normal saline group, t = 7.2197, p = 0.0000. Conclusion: The traditional Chinese antitumor medicine, sal ammoniac and its main effective components have good antitumor effect, which can be further popularized and applied in clinical practice.

The Coronavirus Disease 2019 (COVID-19) pandemic has increased the public health burden and brought profound disaster to humans. For the particularity of the COVID-19 medical images with blurred boundaries, low contrast and different infection sites, some researchers have improved the accuracy by adding more complexity. Also, they overlook the complexity of lesions, which hinder their ability to capture the relationship between segmentation sites and the background, as well as the edge contours and global context. However, increasing the computational complexity, parameters and inference speed is unfavorable for model transfer from laboratory to clinic. A perfect segmentation network needs to balance the above three factors completely. To solve the above issues, this paper propose a symmetric automatic segmentation framework named MS-DCANet. We introduce Tokenized MLP block, a novel attention scheme that use a shift-window mechanism to conditionally fuse local and global features to get more continuous boundaries and spatial positioning capabilities. It has greater understanding of irregular lesions contours. MS-DCANet also uses several Dual Channel blocks and a Res-ASPP block to improve the ability to recognize small targets. On multi-modality COVID-19 tasks, MS-DCANet achieved state-of-the-art performance compared with other baselines. It can well trade off the accuracy and complexity. To prove the strong generalization ability of our proposed model, we apply it to other tasks (ISIC 2018 and BAA) and achieve satisfactory results., Comment: 21pages,13 figures,9 tables

Comunicación expuesta online en el CYGNSS Science Team Summer Meeting celebrado del 27 al 29 de julio de 2021

Land surface temperature and emissivity separation (TES) is a key problem in thermal infrared (TIR) remote sensing. Along with the development of civil applications, increasing numbers of man-made low-emissivity materials can be found around our living environment. In addition, the characteristics and variation in properties of those materials should also be concerned. However, there are still few TES methods for low-emissivity materials reported in the literature. This paper addresses the performance of the automatic retrieval of temperature and emissivity using spectral smoothness (ARTEMISS) method proposed by Borel (2008) for the retrieval of temperature and emissivity from hyperspectral TIR data for low-emissivity materials. The results show that those modeling errors are less than 0.11 K for temperature and 0.3% for emissivity as shown in the ARTEMISS algorithm if atmospheric parameters and the mean emissivity of material spectra are known. A sensitivity analysis has been performed, and the results show that the retrieval accuracy will be degraded with the increase of instrument noises, the errors of the atmospheric parameters, and the coarser spectral resolution. ARTEMISS can give a reasonable estimation of the temperature and emissivity for high- and low-emissivity materials; however, the performance of the algorithm is more seriously influenced by the atmospheric compensation than by the instrument noises. Our results show that the errors of temperature and emissivity become approximately three times than that when the instrument spectral properties are $1{\text{ cm}}^{-1}$ of sampling interval and $2{\text{ cm}}^{-1}$ of FWHM, and $4{\text{ cm}}^{-1}$ of sampling interval and $8{\text{ cm}}^{-1}$ of FWHM, respectively.

This paper presents a noise removal method based on a semi-adaptive threshold in anisotropic diffusion filter to get better detail information protection and stronger noise suppressing ability. In this model, a method of local difference value is applied to distinguish corrupted pixels and noise-free pixels, and parts of the corrupted pixels are replaced by the pixels which have been pre-denoised through a Gaussian filter. Then an anisotropic diffusion model with a semi-adaptive threshold in diffusion coefficient function is applied to get a restored image. In order to implement the semi-adaptive threshold for each diffusion, the gradient value of the corrupted pixels is introduced in the threshold, which results in more diffusion in smooth areas and less diffusion in boundary regions. Compared with the traditional anisotropic diffusion models, the experimental results show that the proposed method can improve the PSNR by 30% and SSIM by 5%. The filtered images and experimental data indicate that the proposed method performs efficiently in both edge preservation and noise removing. A new anisotropic diffusion filter based on a semi-adaptive threshold is proposed.A novel method with local difference value is applied to extract corrupted pixels.The improved method performs well in both edge preservation and noise removing.

The rapid urbanization is giving changes to China's appearance. Urban areas, for their own sake, are encroach- ing on lands and villages. The traditional villages are open to exploitation for the development of tourism. They are se- verely destroyed and the buildings significantly altered for more economic benefits. The traditional culture has been lost; instead, modern villages are constructed. People have no idea about that the preservation of traditional villages can actu- ally bring more benefits. The villages can be found in the specific environment and space, and traditional culture in these villages. The well preserved landscape of the villages lays foundation and is the prerequisite for their development. Among the 4,000 ancient towns in Sichuan Province in China, more than 1,000 of them are historically important and de- serve preservation. This paper will study Shangli Town, a traditional one in the low hilly western areas in Sichuan, focus on the relation between its physical form and its traditional culture, and try to understand the deep structure which forms the featured landscape of the traditional village, so as to preserve the landscape features of the traditional villages and re- vitalize them in a real sense. basin. There are over 4,000 ancient towns in Sichuan (2), and over 1,400 with historical value have remained, most of which are located in the hilly areas. The terrain rises and falls, and is largely related to the river water system. The farm town in the hilly area, compared with those in the plain, is more closely related to natural landscapes. It has become a landscape for there are different views from different dis- tances. Shangli Town in Yaan City in Sichuan is located at the border of Yaan, Lushan, Mingshan, and Qionglai. It is a remote town which keeps the productive, social, and cultural form of an agrarian society. Plans to protect its landscape features were made in the 1980s; therefore, it has been well preserved and is a typical hill-featured town. This paper is aimed to analyze its natural environment, buildings, and cul- tural landscape, make comprehensive understanding and exploration of the value of its landscape, and bring forward proposals to realize the sustainable development of the tradi- tional villages in the hilly area in Sichuan which strive to maintain their landscape features and historical culture dur- ing the urbanization in China. This article content has no conflict of interest

Old town is like living fossil which has accumulated rich historical connotations; the one carrying the history of a region’s political, economic, cultural and ecological changes as well as the formative art created by collective labors and wisdoms of generations. The preservation of ancient Chinese dwellings and old towns began late; many historical architectures and traditional country fairs are forcibly removed during the transformation of old cities and towns, thus ancient towns with their original historical looks are becoming less and less. In comparison, the preservation and development of old western towns started earlier than China; with rich experience, they offer good examples for China, especially the successful developing way: eco-tourism. By comparing the preservation and development of traditional Chinese towns’ landscape features to that of western ones, this paper points out that the future development of old towns rely on proper handling of the relation between preserving and the feasibility of renewing, so as to maintain the landscape features of old towns in the course of sustainable development. Key words: Traditional Changzhen, landscape environment, sustainable development, preservation.

European eel (Anguilla anguilla) is a crucial economic fish that has been plagued by Aeromonas hydrophila infections for many years. Vaccines that are cross-protective against multiple serotypes could provide an effective control against A. hydrophila-mediated diseases. The outer membrane proteins (OMPs) are highly immunogenic and capable of eliciting protective immune responses. This study reports the identification of a novel 46 kD maltoporin that is a conserved protective antigen for different serotypes of A. hydrophila. First, this study purified OMPs from the strains of A. hydrophila B10, B11, B12, B15, B19, and B20. Western blot analysis revealed that the 46 kD maltoporin of B11 could be strongly reacted with all the specific European eel antisera against the above OMPs from different serotypes A. hydrophila. Cloning and sequencing of the maltoporin revealed that it contains an open reading frame (ORF) of 1281 nucleotides encoding 426 amino acids. Further sequence alignment analysis using the NCBI Conserved Domain Database (CDD) along with performing three-dimensional structure analysis showed that this protein belongs to maltoporin family. Three different study groups of European eels were intraperitoneal injected with one of the following conditions: phosphate-buffered saline (PBS group), formaline-killed-whole-cell (FKC) of A. hydrophila (FKC group) or with the recombinant maltoporin (OMP group) to analyze the immunogenicity of the recombinant maltoporin purified by nickel chelate affinity chromatography. On 14, 21, 28 and 42 days post-vaccination respectively, proliferation of the whole blood cells, titers of specific antibody, and lysozyme activities of experimental eels were detected. On 28d post-vaccination, eels from the three groups were challenged by intraperitoneal injection with five different live strains of A. hydrophila (B10, B11, B15, B19, and B20). The results showed that the proliferation of whole blood cells in the OMP group was significantly enhanced on 14d and the serum antibody titers of vaccinated European eels in FKC and OMP group were significantly increased on 28d and 42d. Lysozyme activities in serum were significantly up-regulated in FKC and OMP groups on 21d. The relative percent survival (RPS) of OMP group challenged by A. hydrophila B10, B11, and B20 was 75%, 62.5%, and 88%. This was higher than the corresponding RPS of FKC group with 50%, 37.5%, and 66%, respectively. The RPS was up to 100% in both OMP and FKC group when challenged by A. hydrophila B15 and B19. These results indicate that the 46 kD maltoporin is an effective potent vaccine candidate against different serotypes of A. hydrophila.

One of the crucial issue in image quality enhancement is the fidelity issue. There are three fidelity issues to must be studied. The 1st fidelity issue can be called that the information entropy of the enhanced image can not be increase. The 2nd fidelity issue can be called that the constituents of the enhanced image can not be increased. The 3rd fidelity issue can be called that the color relation of the enhanced image can not be changed. MSRCR will be used as an example of an image enhancement method based on the retinex series method. As an example, the three fidelity brought by multi-scale retinex with color restoration (MSRCR), which is one of series methods based on retinex, will be studied in this paper. The study will point out that the MSRCR will result in the three obvious distortions above mentioned.

To meet the requirement of real-time processing, an image stitching method based on memory space conversion is proposed. In this method, two banks in a DDR2 SDRAM are used for storing image data alternately to realize the image stitching with image translation and rotation in hardware. The store addresses of two images are calculated based on the given stitching parameters and Bresenham algorithm. This algorithm results in smaller calculation and lower implementation cost. An arbiter scheme is proposed to meet the strict timing requirements of memory writing and reading. To ensure the timing synchronization of visual information from two image sensors, a judge module is used to determine which image should be stored first. Finally the systematic circuit simulation is conducted and the simulation results are compared with the mathematical model. Experimental results show that the proposed method not only avoids the multiplication, but also reduces the addition by 93.75%. It can improve the computation efficiency and decrease the complexity of hardware circuit on the basis of guaranteeing the image quality.