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Supplementary Material 1

This scoping review aims to summarize the existing evidence on Bojungikki-tang for cancer, especially focusing on immunological effects and safety.

본 연구는 최근 급증하는 10대 미혼모 문제를 사회복지적 관점에서 질적 분석 방법을 통하여 연구하여 그 대안을 제시하고자 하는 목적에서 시작하였다. 이 목적을 달성하기 위하여 출산 후 1년 이내의 자녀를 양육하고 있으며, 원가족의 도움을 받지 않고 분리하여 생활하고 있는 3명을 연구 대상자로 하였다. 연구 참여자 선정은 눈덩이 표집법을 사용하여 참여자들로부터 소개받는 형식을 취하였다. 참여자의 인터뷰 기간은 2018년 6월부터 10일까지이며, 1인당 2-3회의 면담을 하였다. 면담이 필요할 때는 추가로 전화면담을 하였다. 면담시간은 1시간 30분에서 2시간이었다. 면담결과 50개의 의미단위, 14개의 하위범주, 4개의 범주로 분석되었다. 면담결과를 바탕으로 미혼모도 살아갈 수 있는 다양한 가족형태를 인정하고 국가에서는 미혼모를 위한 지원책 즉, 사회적·경제적 프로그램과 양육프로그램 지원이 필요함을 제시하였다

As a result of their close similarities to the inorganic mineral components of human bone, hydroxyapatite nanoparticles (n-HAp) are widely used in biomedical applications and for the elaboration of biocompatible scaffold drug delivery systems for bone tissue engineering. In this context, a new efficient and economic procedure was used for the consolidation of n-HAp in the presence of various

Additional file 2: Table S1. Diagnostic criteria of MEN1 *[2]

Additional file 1: Supplementary Fig. 1. (A) Pedigree chart of the patient. The index patient and his son carry the same MEN1 gene mutation. (B) DNA sequencing shows a heterozygous missense mutation in exon 3 (p.Val215Met).

As a result of their close similarities to the inorganic mineral components of human bone, hydroxyapatite nanoparticles (n-HAp) are widely used in biomedical applications and for the elaboration of biocompatible scaffold drug delivery systems for bone tissue engineering. In this context, a new efficient and economic procedure was used for the consolidation of n-HAp in the presence of various Nigella sativa (NS) fractions at a near-room temperature. The research conducted in the present study focuses on the physicochemical properties of loaded n-HAp 3D scaffolds by NS fractions and the in vitro antibacterial activity against Gram-negative (Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 27853), and Gram-positive (Staphylococcus aureus ATCC 29213, Enterococcus faecalis ATCC 700603) bacteria. In order to better understand the effect of the inserted fractions on the HAp molecular structure, the elaborated samples were subject to Fourier transform infrared (FTIR) and X-ray diffraction (XRD) spectroscopic analyses. In addition, the morphological investigation by scanning electron microscope (SEM) of the loaded n-HAp 3D scaffolds demonstrated the presence of a porous structure, which is generally required in stimulating bone regeneration. Furthermore, the fabricated 3D composites exhibited significant antibacterial activity against all tested bacteria. Indeed, MIC values ranging from 5 mg/mL to 20 mg/mL were found for the HAp-Ethanol fraction (HAp-Et) and HAp-Hexane fraction (HAp-Hex), while the HAp-Aqueous fraction (HAp-Aq) and HAp-Methanol fraction (HAp-Me) showed values between 20 mg/mL and 30 mg/mL on the different strains. These results suggest that the HAp-NS scaffolds were effective as a drug delivery system and have very promising applications in bone tissue engineering.

Additional file 1: Table S1. Baseline characteristics of AML patients.

Additional file 3: Table S3. Univariate analysis for AML patients.

Additional file 4: Figure S1. The expression of CD45dim population on bone marrow cells in the study.

Additional file 2: Table S2. Patient characteristics.

Supplemental material, Supplementary_Information_20190124 for Radotinib inhibits mitosis entry in acute myeloid leukemia cells via suppression of Aurora kinase A expression by Sook-Kyoung Heo, Eui-Kyu Noh, Yoo Kyung Jeong, Lan Jeong Ju, Jun Young Sung, Ho-Min Yu, Jaekyung Cheon, SuJin Koh, Young Joo Min, Yunsuk Choi and Jae-Cheol Jo in Tumor Biology

Supplemental material, DS1_JVDI_10.1177_1040638719832071 for Evaluation of a human glycated hemoglobin test in canine diabetes mellitus by Na-Yon Kim, Jaehoon An, Jae-Kyung Jeong, Sumin Ji, Sung-Hyun Hwang, Hong-Seok Lee, Myung-Chul Kim, Hyun-Wook Kim, Sungho Won and Yongbaek Kim in Journal of Veterinary Diagnostic Investigation

Silicon dioxide particles are used as an important inorganic material because of its high melting point, rigidity, thermal stability, and unusual mechanical properties [1]. Thus, it presents a wide range of applications such as supercapacitor, batteries, transistor, sensors, and electronic thin film substrates [2–5]. The quality of these products is highly dependent on the size and its distribution [6]. Various methods have been reported for the preparation of the silica particles, including plasma synthesis [7], chemical vapor deposition [8], sol-gel processing [9, 10], chemical precipitation [11], micro emulsion processing [12], combustion synthesis [13, 14], hydrothermal technique, and pressurized carbonation [15]. We used a new method for preparation of silicon dioxide particles by spin coating. Spin coating is a procedure used to apply uniform thin films onto flat substrates. It has been used for several decades for the application of thin film. A typical process involves depositing a small puddle of a fluid resin onto the center of a substrate and then spinning the substrate

Table S1. Clinical characteristics of subjects according to subclinical carotid atherosclerosis and UKPDS risk engine score. Table S2. Changes in treatment patterns after knowledge of subclinical carotid atherosclerosis results according to UKPDS risk engine score. (DOCX 33Â kb)