6 results on '"Jarle Jakobsen"'
Search Results
2. Early detection of prostate cancer in firefighters: a register-based study of prognostic factors and survival
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Kristina Kjærheim, Sophie D. Fosså, Marit B. Veierød, Jarle Jakobsen, Bato Hammarstrom, and Tom Kristian Grimsrud
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Male ,medicine.medical_specialty ,Population ,urologic and male genital diseases ,Lower risk ,Occupational safety and health ,Prostate cancer ,Internal medicine ,medicine ,Humans ,Age of Onset ,Occupations ,education ,Early Detection of Cancer ,education.field_of_study ,Performance status ,Norway ,business.industry ,Incidence (epidemiology) ,Public Health, Environmental and Occupational Health ,Prostatic Neoplasms ,Prostate-Specific Antigen ,Prognosis ,medicine.disease ,Cancer registry ,Military personnel ,Firefighters ,business - Abstract
ObjectivesTo examine age at diagnosis, prognostic factors and survival of prostate cancer (PCa) in Norwegian firefighters and three other occupations undergoing occupational health check-ups, and comparing with PCa cases in the general population.MethodsAll PCa cases diagnosed in 1960–2017 were extracted from the Cancer Registry of Norway. Firefighters, military employees, pilots and police officers were identified through occupational data from Statistics Norway. Age at diagnosis, clinical stage, prostate-specific antigen (PSA), Gleason score, performance status and overall survival and PCa-specific survival in cases in these occupations were compared with cases in the general population.ResultsFirefighters were significantly younger at PCa diagnosis than cases in the general population in 1960–1993 (mean difference: 2.1 years) and 2007–2017 (mean difference: 4.3 years). At diagnosis, firefighters had significantly lower PSA values, Gleason scores and performance status scores than the general population. Firefighters diagnosed in 2007–2017 had lower risk of all-cause death than the general population (crude HR 0.71 (0.53–0.95)). No difference remained after adjusting for age at diagnosis (HR 1.03 (0.77–1.37)). Firefighters were older at diagnosis in 1994–2006 (mean difference: 3.0 years), but showed no other significant differences in age at diagnosis, PSA values, Gleason scores or performance status compared with military employees, pilots and police officers.ConclusionsYounger age and better prognostic factors at PCa diagnosis among firefighters and other occupations with requirements for health check-ups than cases in the general population may indicate an increased diagnostic intensity, likely contributing to elevated PCa incidence in such occupations.
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- 2021
3. Work Conditions and Practices in Norwegian Fire Departments From 1950 Until Today: A Survey on Factors Potentially Influencing Carcinogen Exposure
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Raymond Olsen, Jarle Jakobsen, Tom Kristian Grimsrud, Ronnie Babigumira, Cecilie Rosting, Marie Danielsen, Marit B. Veierød, and Kristina Kjærheim
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Population ,Firefighting ,Norwegian ,chemistry.chemical_compound ,Environmental health ,Medicine ,Safety, Risk, Reliability and Quality ,education ,Cancer ,Flammable liquid ,education.field_of_study ,Chemical Health and Safety ,business.industry ,lcsh:Public aspects of medicine ,Public Health, Environmental and Occupational Health ,lcsh:RA1-1270 ,Occupational exposure ,language.human_language ,Increased risk ,Work (electrical) ,chemistry ,Firefighters ,language ,Original Article ,business ,Safety Research - Abstract
Background Meta-analyses have shown firefighters to be at an increased risk of several cancer types. Occupational carcinogen exposure may explain these increased risks. This study aims to describe Norwegian fire departments' work conditions from 1950 until today, focusing on factors relevant for potential occupational carcinogen exposure. Methods With the help of a reference group, we developed a questionnaire on topics related to occupational exposure to carcinogens for the period 1950–2018. Selected Norwegian fire departments provided department-specific responses. Results Sixteen departments, providing fire services for 48% of the Norwegian population as of 2019 and mainly consisting of professional firefighters, responded to our questionnaire. The introduction of synthetic firefighting foams, more regular live fire training, the introduction of chemical diving, and a higher number of diesel-driven fire service vehicles were identified as changes thought to increase exposure to occupational carcinogens. Changes thought to decrease exposure included the switch from negative to positive pressure self-contained breathing apparatuses, the use of self-contained breathing apparatuses during all phases of firefighting, the use of ventilating fans during firefighting, increased attention to flammable materials used during live fire training, increased attention to handling and cleaning of turnout gear and other equipment, and installment of exhaust removal systems in apparatus bays. Conclusion Norwegian fire departments' work conditions have seen several changes since 1950, and this could influence firefighters' occupational carcinogen exposure. A peak of carcinogen exposure may have occurred in the 1970s and 1980s before recent changes have reduced exposure.
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- 2020
4. Comparison of cancer incidence and mortality in the Norwegian Fire Departments Cohort, 1960-2018
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Niki Marjerrison, Jarle Jakobsen, Paul A Demers, Tom K Grimsrud, Johnni Hansen, Jan Ivar Martinsen, Karl-Christian Nordby, Marit B Veierød, and Kristina Kjærheim
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Public Health, Environmental and Occupational Health - Abstract
ObjectivesElevated risk of cancer at several sites has been reported among firefighters, although with mixed findings. The purpose of this study was to calculate standardised incidence ratios (SIRs) and standardised mortality ratios (SMRs) for cancer and compare them to assess whether use of the different measures could be a source of inconsistencies in findings.MethodsThe Norwegian Fire Departments Cohort, comprising 4295 male employees who worked at 15 fire departments across Norway, was linked to health outcome registries for the period 1960–2018. SIRs and SMRs were derived using national reference rates.ResultsOverall, we observed elevated incidence of colon cancer (SIR, 95% CI 1.27, 1.01 to 1.58), mesothelioma (2.59, 1.12 to 5.11), prostate cancer (1.18, 1.03 to 1.34) and all sites combined (1.15, 1.08 to 1.23). Smaller, non-significant elevations were found for mortality of colon cancer (SMR, 95% CI 1.20, 0.84 to 1.67) and mesothelioma (1.66, 0.34 to 4.86), while SMR for prostate cancer was at unity. Potential errors were observed in some of the mortality data, notably for mesothelioma cases. Among those who died of cancer, 3.7% (n=14) did not have a prior diagnosis of malignancy at the same site group.ConclusionsAssessment of incidence or mortality did not greatly influence the interpretation of results. The most prominent differences in SIR and SMR appeared to be due to inconsistencies between sites of cancer diagnosis and cause of death. The difference in SIR and SMR for prostate cancer suggested a detection bias from differential screening practices.
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- 2022
5. Cancer incidence in sites potentially related to occupational exposures: 58 years of follow-up of firefighters in the Norwegian Fire Departments Cohort
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Niki Marjerrison, Jarle Jakobsen, Tom K Grimsrud, Johnni Hansen, Jan Ivar Martinsen, Karl-Christian Nordby, Marit B Veierød, and Kristina Kjærheim
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Male ,Mesothelioma ,Occupational Diseases ,Firefighters ,Incidence ,Neoplasms ,Occupational Exposure ,Public Health, Environmental and Occupational Health ,Humans ,Follow-Up Studies - Abstract
Objectives Firefighters are exposed to a variety of known and suspected carcinogens through their work. However, the association with cancer risk has limited evidence. We examined cancer incidence among firefighters in the newly established Norwegian Fire Departments Cohort restricted to sites with established associations with carcinogens encountered during firefighting. This included sites within the respiratory, urinary, and lympho-hematopoietic systems, and the skin and all sites combined. Methods Male firefighters (N=3881) in the cohort were linked to the Cancer Registry of Norway for incident cancer cases occurring during the period 1960–2018. We calculated standardized incidence ratios (SIR) with rates for the national male population as reference, and stratified SIR analyses by period of first employment, duration of employment, and time since first employment. Results Elevated risk was seen for all sites combined (SIR 1.15, 95% confidence interval 1.07–1.23). Elevated risk of urinary tract cancer was observed among firefighters who began working before 1950, and with observation ≥40 years since first employment. Risk of mesothelioma and laryngeal cancer were elevated with ≥40 years since first employment and with ≥30 years employment duration. Conclusions The observed associations between firefighting and urinary tract cancer, laryngeal cancer, and mesothelioma have been observed in some studies previously, and our results suggest the observed elevated risks are related to carcinogenic occupational exposures. Differences in risk by period of employment potentially reflect changes in exposures from improved quality and use of personal protective equipment.
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- 2022
6. O-392 Early detection of prostate cancer in firefighters – a register-based study of prognostic factors and survival
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Jarle Jakobsen, Marit B Veierød, Kristina Kjaerheim, Tom K Grimsrud, Sophie Dorothea Fosså, and Bato Hammarström
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- 2021
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