1. The Hip of Children with Congenital Zika Syndrome: A Prospective Observational Study
- Author
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Jakeline Oliveira da, Fonseca, Renata Artimos de Oliveira, Vianna, Fabiana Rabe, Carvalho, Luis Guillermo Coca, Velarde, Solange Artimos, de Oliveira, Claudete Aparecida Araújo, Cardoso, and Vinícius Schott, Gameiro
- Subjects
Pediatrics, Perinatology and Child Health - Abstract
To assess the clinical and radiographic characteristics of hip joint deformities in children with congenital Zika syndrome (CZS), and the evolution of hip joint deformities in affected infants for the first three years of life.This prospective observational study evaluated orthopedic clinical examinations performed every 3 months to assess hip flexion and extension, lateral and medial rotation, abduction and adduction, as well as lower limb muscle length and tone. The biannual radiograph comprised anteroposterior panoramic pelvic radiographs with the lower limbs in extension. Percentage of migration was used as a radiographic study tool to measure and evaluate linear hip displacement.From November 2018 to March 2020, we followed 30 children with CZS, of which 15 (50%) had normal pelvic radiographs on admission; five (33.3%) developed hip displacement by the second radiograph exam. During follow up radiographic examinations, 20/30 (66.7%) children were diagnosed with hip displacement and/or dislocation of at least one side, and 10/30 (33.3%) remained normal. Among 30 affected patients, 13 (43.3%) had hip displacement on the right side and 9 (30%) on the left side. Logistic regression analysis revealed that spasticity (p=0.0033; OR=15.9) and ophthalmologic abnormalities (p=0.0163; OR=16.9) were associated with hip dislocation during follow up.Pelvic radiographic follow up for all children with CZS will complement physical examination, diagnosis, and monitoring for hip joint deformities.
- Published
- 2023
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