Search

Your search keyword '"Jégu, M."' showing total 5 results
Start Over Author "Jégu, M." Language undetermined
5 results on '"Jégu, M."'

2. Les Hommes et le Milieu

Author

Frédéric Meunier, Hélène Pagezy, Philippe Keith, Jégu, M., Eco-Anthropologie et Ethnobiologie (EAE), Muséum national d'Histoire naturelle (MNHN)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Biodiversité et dynamique des populations aquatiques, Biologie des organismes marins et écosystèmes (BOME), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Muséum national d'Histoire naturelle (MNHN), F.J. Meunier, Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Muséum national d'Histoire naturelle (MNHN)

Subjects
[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropology

3. [Breast and ovarian cancer due to BRCA1&2 hereditary cancer predisposition syndrome and reproduction: literature review]

Author

Jégu M, Some Der A, Morcel K, Abadie C, Xavier FRITEL, and Levêque J

Subjects
Male, Ovarian Neoplasms, Reproduction, Genes, BRCA2, Genes, BRCA1, Breast Neoplasms, Syndrome, Breast Feeding, Fertility, Pregnancy, Mutation, Humans, Female, Genetic Predisposition to Disease
Abstract

Germline mutations BRCA12 are responsible in women for breast and ovarian cancers that commonly occur at a young age: as such, there are strong interactions between the oncological risks and the events of reproductive life, pregnancy, breastfeeding, and management of infertility.A review of the international literature from the PubMed database was conducted, and recommendations of French health agencies were exposed. Published studies are case-control and cohort studies in the majority, with a low level of evidence.Pregnancy and lactation have no effect on breast and ovaries or even decreases the risk. The sex ratio among patients carrying the mutation is in favor of girls. It is not observed more infertility in patients carrying a mutation despite a strong suspicion of premature ovarian failure, and infertility treatments do not increase breast and ovarian risk. There are ethical debates concerning the place of pre-natal diagnosis: both experts and concerned patients recommend a case-by-case analysis of the requests.

Catalog

Books, media, physical & digital resources
See catalog results