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Your search keyword '"Ishikawa, Kazuki"' showing total 3 results
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3 results on '"Ishikawa, Kazuki"'

1. Additional file 1 of Organs-at-risk dose constraints in head and neck intensity-modulated radiation therapy using a dataset from a multi-institutional clinical trial (JCOG1015A1)

Author

Inada, Masahiro, Nishimura, Yasumasa, Ishikura, Satoshi, Ishikawa, Kazuki, Murakami, Naoya, Kodaira, Takeshi, Ito, Yoshinori, Tsuchiya, Kazuhiko, Murakami, Yuji, Saito, Junichi, Akimoto, Tetsuo, Nakata, Kensei, Yoshimura, Michio, Teshima, Teruki, Toshiyasu, Takashi, Ota, Yosuke, Minemura, Toshiyuki, Shimizu, Hidetoshi, and Hiraoka, Masahiro

Abstract

Additional file 1. Table S1. Results of receiver operator characteristic analysis in each late toxicity.

Published
2022
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3. Isolation and identification of berberine and berberrubine metabolites by berberine-utilizing bacterium Rhodococcus sp. strain BD7100

Author

Ishikawa, Kazuki, Takeda, Hisashi, Daigo Wakana, Sato, Fumihiko, and Hosoe, Tomoo

Abstract

Based on the finding of a novel berberine (BBR)-utilizing bacterium, Rhodococcus sp. strain BD7100, we investigated the degradation of BBR and its analog berberrubine (BRU). Resting cells of BD7100 demethylenated BBR and BRU, yielding benzeneacetic acid analogs. Isolation of benzeneacetic acid analogs suggested that BD7100 degraded the isoquinoline ring of the protoberberine skeleton. This work represents the first report of cleavage of protoberberine skeleton by a microorganism. BBR-utilizing bacterium, Rhodococcus sp. BD7100 demethylenated BBR and BRU, yielding benzeneacetic acid analogs in which their protoberberine skeletons were cleaved.

Published
2016
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