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2. Epilepsy in children and adolescents with type 1 diabetes: The course and diagnosis features

Author

Koltunov Ie, E. E. Petryaykina, I. O. Schederkina, and I. G. Rybkina

Subjects
musculoskeletal diseases, Autoimmune disease, Heterogeneous group, business.industry, medicine.disease, Lesion, Epilepsy, Chronic hyperglycemia, Diabetes mellitus, Pediatrics, Perinatology and Child Health, Immunology, medicine, Endocrine system, medicine.symptom, business
Abstract

Diabetes mellitus type 1 (DM1) is an etiologically heterogeneous group of metabolic diseases characterized by chronic hyperglycemia. This autoimmune disease develops in people genetically predisposed to it. DM1 can combine with other autoimmune diseases, with lesion of both endocrine and not endocrine tissues. The coexistence of these diseases may indicate a genetic predisposition to this combination, but may be a coincidence. With endocrine diseases, seizures can be the result of neuroinflammatory, autoimmune and metabolic disorders. The article discusses problems of DM1 and epilepsy combination in children, features of epilepsy course, its forms and tactics of management of patients with the combination of these diseases.

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