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Supplemental material, sj-docx-1-npx-10.1177_1934578X221074526 for Extensive Phytochemical Assessment of Dendrobium fimbriatum Hook (Orchidaceae) by Quentin Favre-Godal, Jane Hubert, Alexis Kotland, Delphine Garnier, Camille Beaugendre, Lorène Gourguillon, Aurelie Urbain, Sonia Lordel-Madeleine and Patrick Choisy in Natural Product Communications

Supplemental material, sj-docx-1-npx-10.1177_1934578X221074526 for Extensive Phytochemical Assessment of Dendrobium fimbriatum Hook (Orchidaceae) by Quentin Favre-Godal, Jane Hubert, Alexis Kotland, Delphine Garnier, Camille Beaugendre, Lorène Gourguillon, Aurelie Urbain, Sonia Lordel-Madeleine and Patrick Choisy in Natural Product Communications

Supplemental material, Supplementary material, for Investigation of Antioxidant and Elastase Inhibitory Activities of Geum urbanum Aerial Parts, Chemical Characterization of Extracts Guided by Chemical and Biological Assays by Marie Schmitt, Abdulmagid Alabdul Magid, Jean-Marc Nuzillard, Jane Hubert, Nicolas Etique, Laurent Duca and Laurence Voutquenne-Nazabadioko in Natural Product Communications

A new phorbol-type diterpene ester, 4,20-dideoxy-4α-phorbol-12β-acetate-13α-isobutyrate, in addition to 11 known compounds were isolated from the latex and roots of Euphorbia clementei Boiss. Structure elucidation was performed by comprehensive 1D and 2D NMR analyses (1H and 13C NMR, COSY, ROESY, HSQC and HMBC experiments), mass spectrometry (HR-ESI-MS) and by comparison with literature data. The inhibitory activity of all isolated compounds was evaluated against promyelocytic leukemia HL60 and human erythromyeloblastoid leukemia K562 cell lines and seven of these compounds exhibited a weak cytotoxicity with IC50 values ranging from 40 to 97 μM.

A new phorbol-type diterpene ester, 4,20-dideoxy-4α-phorbol-12β-acetate-13α-isobutyrate, in addition to 11 known compounds were isolated from the latex and roots of Euphorbia clementei Boiss. Structure elucidation was performed by comprehensive 1D and 2D NMR analyses (1H and 13C NMR, COSY, ROESY, HSQC and HMBC experiments), mass spectrometry (HR-ESI-MS) and by comparison with literature data. The inhibitory activity of all isolated compounds was evaluated against promyelocytic leukemia HL60 and human erythromyeloblastoid leukemia K562 cell lines and seven of these compounds exhibited a weak cytotoxicity with IC50 values ranging from 40 to 97 μM.