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1. Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension

Author

Paul Muntner, Anastasios Kollias, Paul L. Padfield, Jonathan Mant, George S. Stergiou, Juan Eugenio Ochoa, Richard J McManus, Martino F Pengo, Thomas Mengden, James E. Sharman, Satoshi Hoshide, Geoff Head, G. Mancia, Stefano Omboni, A. de la Sierra, Cristina Giannattasio, Anastasia S. Mihailidou, William B. White, Agustin J. Ramirez, Kazuomi Kario, Paolo Palatini, Angeliki Ntineri, Michael A. Weber, Ji-Guang Wang, Kei Asayama, Eoin O'Brien, Rajiv Agarwal, Y. Imai, R. Asmar, José A. Octavio, Nicolas Postel-Vinay, Martin G. Myers, Grzegorz Bilo, Jirar Topouchian, Efstathios Manios, Camilla Torlasco, Andrew Shennan, Gianfranco Parati, Egle Silva, Paul K. Whelton, Y. Li, Philippe Gosse, Takayoshi Ohkubo, Dario Pellegrini, Teemu J. Niiranen, Michel Burnier, Parati, G, Stergiou, G, Bilo, G, Kollias, A, Pengo, M, Ochoa, J, Agarwal, R, Asayama, K, Asmar, R, Burnier, M, De La Sierra, A, Giannattasio, C, Gosse, P, Head, G, Hoshide, S, Imai, Y, Kario, K, Li, Y, Manios, E, Mant, J, Mcmanus, R, Mengden, T, Mihailidou, A, Muntner, P, Myers, M, Niiranen, T, Ntineri, A, O'Brien, E, Octavio, J, Ohkubo, T, Omboni, S, Padfield, P, Palatini, P, Pellegrini, D, Postel-Vinay, N, Ramirez, A, Sharman, J, Shennan, A, Silva, E, Topouchian, J, Torlasco, C, Wang, J, Weber, M, Whelton, P, White, W, and Mancia, G

Subjects
cardiovascular risk, CHRONIC KIDNEY-DISEASE, 2019-20 coronavirus outbreak, hypertension, Coronavirus disease 2019 (COVID-19), blood pressure measurement, Physiology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), MEDLINE, ORTHOSTATIC HYPOTENSION, TARGET-ORGAN DAMAGE, Blood Pressure, MEDICAL INSTRUMENTATION/EUROPEAN SOCIETY, cardiovascular disease, SELF-MEASUREMENT, Internal Medicine, medicine, Humans, prevention and control, Blood pressure monitoring, Hypertension diagnosis, Societies, Medical, Science & Technology, business.industry, Blood Pressure Determination, Blood Pressure Monitoring, Ambulatory, medicine.disease, WHITE-COAT HYPERTENSION, home blood pressure monitoring, PROGNOSTIC VALUE, Blood pressure, Peripheral Vascular Disease, MEASURING DEVICES, Hypertension, Cardiovascular System & Cardiology, Position paper, Medical emergency, FOLLOW-UP, Cardiology and Cardiovascular Medicine, business, Life Sciences & Biomedicine, OUTCOME-DRIVEN THRESHOLDS, blood pressure monitorign, home, methodology
Abstract

The present paper provides an update of previous recommendations on Home Blood Pressure Monitoring from the European Society of Hypertension (ESH) Working Group on Blood Pressure Monitoring and Cardiovascular Variability sequentially published in years 2000, 2008 and 2010. This update has taken into account new evidence in this field, including a recent statement by the American Heart association, as well as technological developments, which have occurred over the past 20 years. The present document has been developed by the same ESH Working Group with inputs from an international team of experts, and has been endorsed by the ESH. ispartof: JOURNAL OF HYPERTENSION vol:39 issue:9 pages:1742-1767 ispartof: location:Netherlands status: published

Published
2021

2. Efficacy of olmesartan/amlodipine combination therapy in reducing ambulatory blood pressure in moderate-to-severe hypertensive patients not controlled by amlodipine alone

Author

Grzegorz Bilo, Winfried Koch, Satoshi Hoshide, Gianfranco Parati, Bilo, G, Koch, W, Hoshide, S, and Parati, G

Subjects
Adult, Male, medicine.medical_specialty, Ambulatory blood pressure, Combination therapy, Physiology, Tetrazoles, Blood Pressure, macromolecular substances, Pharmacology, law.invention, Pharmacotherapy, Randomized controlled trial, Double-Blind Method, law, Internal medicine, Internal Medicine, medicine, Olmesartan, Humans, Amlodipine, Antihypertensive Agents, Aged, business.industry, Imidazoles, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Blood Pressure Monitoring, Ambulatory, Middle Aged, ambulatory blood pressure monitoring, Blood pressure, Treatment Outcome, Ambulatory, Hypertension, Retreatment, Cardiology, Drug Therapy, Combination, Female, Cardiology and Cardiovascular Medicine, business, medicine.drug
Abstract

This previously unpublished, preplanned analysis investigated the efficacy of the olmesartan/amlodipine combination at different doses on 24-h blood pressure (BP) control, as well as assessed trough estimation of trough-to-peak ratio (TPR) and smoothness index (SI). Ambulatory BP monitoring was performed in patients with moderate-to-severe hypertension whose BP was inadequately controlled after 8 weeks' treatment with amlodipine 5 mg. Patients were randomized to continue with amlodipine 5 mg or to receive olmesartan/amlodipine 10/5, 20/5 or 40/5 mg for 8 weeks (Period II). Patients not achieving BP control were uptitrated to a more powerful regimen for another 8 weeks (Period III). During Period II, each olmesartan/amlodipine combination reduced 24-h systolic and diastolic BP (SBP/DBP), as well as morning and early morning SBP/DBP, significantly more than amlodipine 5 mg (P0.001 for all). TPRs were higher in each olmesartan/amlodipine group than with amlodipine 5 mg, and SI values showed dose-related increases; olmesartan/amlodipine 40/5 mg produced a significantly higher SI for SBP and DBP (1.55 and 1.33, respectively) than amlodipine 5 mg (0.96 and 0.77, respectively, P0.0001 for each). During Period III, uptitrated patients showed further BP reductions, which were largest in those on olmesartan/amlodipine 40/10 mg. SI values increased in uptitrated patients and were highest with olmesartan/amlodipine 40/10 mg (SBP 1.62/DBP 1.41). The olmesartan/amlodipine combination effectively reduces BP over 24 h, including the morning hours, in a dose-related manner. Compared with amlodipine alone, the olmesartan/amlodipine combination has a better 24-h coverage (TPR) and a dose-related improvement in BP lowering homogeneity (SI).

Published
2013

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