1. NIDA's Clinical Trials Network: an opportunity for HIV research in community substance abuse treatment programs
- Author
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Tross, Susan, Campbell, Aimee NC, Calsyn, Donald A, Metsch, Lisa R, Sorensen, James L, Shoptaw, Steven, Haynes, Louise, Woody, George E, Malow, Robert M, Brown, Lawrence S, Feaster, Daniel J, Booth, Robert E, Mandler, Raul N, Masson, Carmen, Holmes, Beverly W, Colfax, Grant, Brooks, Audrey J, Hien, Denise A, Schackman, Bruce R, Korthuis, P Todd, Miele, Gloria M, and Clinical Trials Network HIV Special Interest Group
- Subjects
Clinical Trials Network ,Comparative Effectiveness Research ,Substance-Related Disorders ,Clinical Trials and Supportive Activities ,HIV Infections ,Substance Misuse ,Clinical Research ,Behavioral and Social Science ,substance abuse ,Humans ,Psychology ,Community Health Services ,Cooperative Behavior ,health care economics and organizations ,effectiveness research ,Clinical Trials as Topic ,National Institute on Drug Abuse (U.S.) ,Prevention ,virus diseases ,United States ,Brain Disorders ,Infectious Diseases ,Good Health and Well Being ,Research Design ,Public Health and Health Services ,HIV/AIDS ,National Institute on Drug Abuse ,Patient Safety ,Drug Abuse (NIDA only) ,Clinical Trials Network HIV Special Interest Group - Abstract
Background/objectivesHIV continues to be a significant problem among substance users and their sexual partners in the United States. The National Drug Abuse Treatment Clinical Trials Network (CTN) offers a national platform for effectiveness trials of HIV interventions in community substance abuse treatment programs. This article presents the HIV activities of the CTN during its first 10 years.ResultsWhile emphasizing CTN HIV protocols, this article reviews the (1) HIV context for this work; (2) the collaborative process among providers, researchers, and National Institute on Drug Abuse CTN staff, on which CTN HIV work was based; (3) results of CTN HIV protocols and HIV secondary analyses in CTN non-HIV protocols; and (4) implications for future HIV intervention effectiveness research in community substance abuse treatment programs.Conclusion/significanceWhile the feasibility of engaging frontline providers in this research is highlighted, the limitations of small to medium effect sizes and weak adoption and sustainability in everyday practice are also discussed.
- Published
- 2011