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We present the first results of the Fermilab Muon g-2 Experiment for the positive muon magnetic anomaly $a_\mu \equiv (g_\mu-2)/2$. The anomaly is determined from the precision measurements of two angular frequencies. Intensity variation of high-energy positrons from muon decays directly encodes the difference frequency $\omega_a$ between the spin-precession and cyclotron frequencies for polarized muons in a magnetic storage ring. The storage ring magnetic field is measured using nuclear magnetic resonance probes calibrated in terms of the equivalent proton spin precession frequency ${\tilde{\omega}'^{}_p}$ in a spherical water sample at 34.7$^{\circ}$C. The ratio $\omega_a / {\tilde{\omega}'^{}_p}$, together with known fundamental constants, determines $a_\mu({\rm FNAL}) = 116\,592\,040(54)\times 10^{-11}$ (0.46\,ppm). The result is 3.3 standard deviations greater than the standard model prediction and is in excellent agreement with the previous Brookhaven National Laboratory (BNL) E821 measurement. After combination with previous measurements of both $\mu^+$ and $\mu^-$, the new experimental average of $a_\mu({\rm Exp}) = 116\,592\,061(41)\times 10^{-11}$ (0.35\,ppm) increases the tension between experiment and theory to 4.2 standard deviations, Comment: 10 pages; 4 figures

Total least squares (TLS) is an effective method for solving linear equations with the situations, when noise is not just in observation matrices but also in mapping matrices. Moreover, the Tikhonov regularization is widely used in plenty of ill-posed problems. In this paper, we extend the regularized total least squares (RTLS) method from the matrix form due to Golub, Hansen and O'Leary, to the tensor form proposing the tensor regularized total least squares (TR-TLS) method for solving ill-conditioned tensor systems of equations. Properties and algorithms about the solution of the TR-TLS problem, which might be similar to those of the RTLS, are also presented and proved. Based on this method, some applications in image and video deblurring are explored. Numerical examples illustrate the TR-TLS, compared with the existing methods.

High processing efficiency and low environmental pollution have been recognized as important goals of sustainable electrical discharge machining (EDM). This paper proposed a sustainable and efficient EDM method called rotating short arc milling. In order to improve the processing efficiency and reduce pollutant emissions, the principles of this method to achieve high material removal rate (MRR), low tool electrode wear rate (TEWR) and environmentally friendly dielectric are described separately. The rotating short arcs generated by the compound field can improve the machining efficiency. The action of the magnetic field and the internal high-pressure dielectric can quickly remove the debris avoiding irregular discharge, thereby improving the machining quality. Due to the attraction effect of the magnetic field on the debris, several debris adhere to the processing end of the tool electrode to form a protective layer and participates in the processing as a part of the tool electrode, which can reduce the tool electrode wear. Tap water is used as the working fluid to reduce pollutants generated during processing. Then, a series of experiments are conducted to study the influence of process parameters on the processing of GH4169 superalloy. The results show that the machining voltage, machining depth and magnetic field strength are the three most important factors that affect the efficiency and sustainability of rotating short arc milling. Furthermore, the optimal process parameters are obtained by using gray relational analysis method to optimize the machining process in terms of high efficiency and environmental protection.

Die Geschichte der Ethnologie beginnt für viele erst ab 1860 mit Adolf Bastian in Deutschland und E.B. Tylor in England oder ab 1887 mit Franz Boas in den USA. So kann man es in den Lehrbüchern lesen: Die Wurzeln der Ethnologie liegen im 19. Jahrhundert; in Deutschland fängt die Ethnologie mit Bastian an. Ähnlich wird die Genese der Anthropologie oft mit dem Wirken von Rudolf Virchow in Berlin verbunden. Meine Recherchen haben jedoch ergeben, dass beide Disziplinen bereits im 18. Jahrhundert entstanden sind, und zwar als parallele Entwicklungen in unterschiedlichen Wissensbereichen. Im Vortrag werde ich hierauf Bezug nehmen und zeigen, dass die Ethnographie 1732-1747 im Rahmen der Erforschung Sibiriens von dem Historiker G.F. Müller als eine beschreibende und vergleichende Studie aller Völker hervortrat; dass die Ethnologie 1771-1775 von A.L. Schlözer in Göttingen als eine allgemeine Völkerkunde eingeführt und 1781-1783 von A.F. Kollár in Wien als ethnologia definiert wurde; und dass die Anthropologie als eine "Naturgeschichte des Menschen" durch Linné in den Jahren 1735-1758, durch Buffon von 1749 bis 1777 und durch Blumenbach in den Jahren 1775-1795 herausgebildet wurde. Diese Entwicklungen kann man bis zur Gründung der BGAEU im Jahr 1869 gut nachvollziehen

© 2017 Elsevier Ltd A type of sandwich-type and mesoporous CoS-based coaxial nanocables with conductive CNT backbone core, well-confined CoS nanoparticle interlayer and conformal carbon coating shell (denoted as CNT@CoS@C) are developed through a bottom-up method and investigated as potential anode materials for sodium/lithium ion storage. The rationally constructed architecture successively achieves the integration of one-dimensional conducting networks, ultrafine active nanoparticles, well-developed mesoporosity and sophisticated surface modification via a layer-by-layer assembly strategy, thus upholding good structural/interfacial robustness and enhanced charge-transfer reaction kinetics. As a result, the CNT@CoS@C coaxial nanocables exhibit a high reversible capacity of 494 mAh g −1 , stable cycling with more than 318 mAh g −1 at 500 mA g −1 over 500 cycles (corresponding to 74% capacity retention with 0.05% decay rate per cycle) and impressive rate capability (278 mAh g −1 at 5000 mA g −1 ) for sodium ion batteries (SIBs) and excellent electrochemical performance for lithium ion batteries (LIBs) (1010 mAh g −1 during 200 cycles with no capacity loss and 467 mAh g −1 at 5000 mA g −1 ). In addition, the electrochemical experimental results and simulated calculations suggest that the CoS-based active species possesses better electrochemical properties in term of reaction reversibility and structural stability than its Co 3 O 4 -based counterpart with similar morphological features.

© The Royal Society of Chemistry 2017. A dragon fruit-like nanostructure consisting of CoS2nanoparticles and co-doped carbon polyhedron is effectively prepared through adjusting the pyrolysis processes of a Co-based zeolitic imidazolate framework (ZIF-67) precursor and subsequent heating sulfidation treatment. It was revealed that ultrafine CoS2nanoparticles with an average particle size of 8 nm are uniformly dispersed and completely encapsulated in the N/S-doped carbon matrix. Such a multifunctional architecture achieves the integration of the favorite traits of ultrafine active nanoparticles and heteroatom-doped carbon matrix, thus giving rise to much improved electron transfer and ion transport, and upholding the structural integrity of the electrode and electrode/electrolyte interface. As an anode for sodium-ion batteries (SIBs), the as-prepared CoS2/C polyhedron electrodes exhibit high reversible capacity and good cycling stability. For example, a reversible specific capacity of 563 mA h g-1and a capacity retention rate of 90% with a remaining capacity of 510 mA h g-1are obtained after 100 cycles at 100 mA g-1. In addition, a superior fast charge-discharge capability is also demonstrated with reversible specific capacities of 307 and 288 mA h g-1at large current densities of 1500 and 2000 mA g-1, respectively. These impressive results indicate that the ZIF-derived synthetic strategy is highly adaptable to design dragon fruit-like nanostructure consisting of metal compounds/carbon nanomaterials with potential applications in high performance electrochemical energy storage devices and other environmental technology fields.

On the island of Ameland (The Netherlands), natural gas has been ex- tracted from a dune and salt marsh natural area since 1986. This has caused a soil subsidence of c. 1-25 cm, which can be used as a model to infer effects of future sea level rise. The aims of our study were (a) to relate the changes in the vegetation, and more specifically, in plant diversity, during the extraction period to soil subsidence and weather fluctuations, and (b) to use these relations to predict future changes due to the combination of ongoing soil subsidence and climate change. We characterised climate change as increases in mean sea level, storm frequency and net precipitation. Simultaneous observations were made of vegetation composition, elevation, soil chemistry, net precipitation, groundwater level, and flooding frequency over the period 1986-2001. By using multiple regression the changes in the vegetation could be decomposed into (1) an oscillatory component due to fluctuations in net precip- itation, (2) an oscillatory component due to incidental flooding, (3) a monotonous component due to soil subsidence, and (4) a monotonous component not related to any measured variable but probably due to eutrophication. The changes were generally small during the observation period, but the regression model predicts large changes by the year 2100 that are almost exclusively due to sea level rise. However, although sea level rise is expected to cause a loss of species, this does not necessarily lead to a loss of conservancy value.

Fibulin-3 gene has been identified as an antagonist of angiogenesis. We investigated the protein expression and promoter methylation status of fibulin-3 gene in colorectal cancer (CRC) and analyzed its correlation with clinicopathological factors. The study population enrolled 85 paired CRC specimens and adjacent normal tissues, as well as 32 cases of colorectal adenoma. Genomic DNA was extracted from paraffin-embedded samples using manual microdissection. Methylation-specific polymerase chain reaction (MSP) was used to determine the promoter methylation status and fibulin-3 gene expression was detected by immunohistochemistry. The results showed that, downregulation or silence of fibulin-3 protein was found in 57.6% (49/85) of CRC tissues, which was significantly higher than that of adjacent normal tissues (28.2%, 24/85) and colorectal adenoma (34.4%, 11/32) (P

Natural wild-type strains of Bacillus subtilis are extensively used in agriculture as biocontrol agents for plants. This study examined two antagonist B. subtilis strains, KB-1111 and KB-1122, and the results illustrated that KB-1122 was a more potent inhibitor of the indicator pathogen than KB- 1111. Thus, to investigate the intrinsic differences between the two antagonist strains under normal culture conditions, samples of KB-1111 and KB-1122 were analyzed using MALDI-TOF-MS. The main differences were related to 20 abundant intracellular and 17 extracellular proteins. When searching the NCBI database, a number of the differentially expressed proteins were identified, including 11 cellular proteins and 10 secretory proteins. Among these proteins, class III stress-response-related ATPase, aconitate hydratase, alpha-amylase precursor, and a secretory protein, endo-1, 4-beta-glucanase, were differentially expressed by the two strains. These results are useful to comprehend the intrinsic differences between the antagonism of KB-1111 and KB-1122.

Objectives Item response theory was used to test the scalability of the Behavioral Dyscontrol Scale (BDS). The BDS assesses the control of voluntary movement, working memory and self-monitoring. Construct validity of the BDS was examined with confirmatory factor analysis. Methods The BDS was administered to 693 consecutive, community-dwelling visitors of a psychogeriatric day unit (424 women and 269 men between the ages of 50 and 94). Unidimensionality of the BDS was determined using Mokken's scalogram analysis. The BDS total score was correlated with other measures of executive function (Expanded Mental Control Test, category fluency, and alternating graphical sequences) and with episodic memory tests of orientation and delayed picture recognition in order to test a model of distinct latent constructs of executive functioning and episodic memory. Results Loevinger's scalability coefficient H was 0.58 for the complete item set of the BDS. Subjects can be ordered on the latent dimension of executive ability. The first eight items of the BDS (deleting the insight rating) satisfy the assumption of non-intersecting item characteristic curves (double monotonicity) which means that they comprise a Guttman-ordered scale (H = 0.60). The BDS and three independent measures of executive control strongly correlated with a latent construct of executive functioning (convergent validity). However, discriminant relations with a nonexecutive construct (recognition memory and orientation) could not be demonstrated. Conclusions The BDS satisfies criteria for scalability according to item response theory. Its construct validity as an executive-specific measure is as yet unclear. Copyright © 2004 John Wiley & Sons, Ltd.

Objectives The study was designed to evaluate the effectiveness of the combination of chemonucleolysis and psoas compartment block (PCB) for the treatment of lumbar disc herniations (LDHs) and to explore the role of PCB in managing postoperative pain of collagenase injection. Methods Two groups of patients (N = 192) were treated in different ways, respectively. Group A (N = 95) was treated with chemonucleolysis only (the injection of oxygen–ozone combined with collagenase into the lumbar disc and the epidural space); group B (N = 97) was treated with chemonucleolysis and PCB. After the treatment, the patients were followed-up, and the therapeutic effect was assessed at 1 week, 1 month, 3 months, and 6 months by the relative pain reduction, visual analog scale (VAS) pain scores, and the Oswestry Disability Index (ODI) scores. Results In group A, treatment success rate was 64.2% (61 of 95), 82.1% (78 of 95), 84.2% (80 of 95), and 86.3% (82 of 95) at 1 week, 1 month, 3 months, and 6 months, respectively. In group B, treatment success rate was 86.5% (84 of 97), 89.6% (87 of 97), 93.8% (91 of 97), and 91.7% (89 of 97) at 1 week, 1 month, 3 months, and 6 months, respectively. There was statistically significant difference in outcome between two groups at 1 week, but there were no statistically significant difference in outcome between two groups at 1 month, 3 months, and 6 months. VAS scores and ODI were significantly decreased in both group A and group B, when compared with the baseline values in the same group at all points of follow-up. Group B produced a significant reduction in the VAS scores and ODI when compared with group A at: 1-week, 1-month, 3-month, 6-month follow-up. Conclusions Computer tomography (CT)-guided chemonucleolysis combined with PCB leads to rapid pain relief, fewer postoperative pain of collagenase injection happen, and should be regarded as a useful treatment for the management of LDH.

Chris Ballard, Jeroen A. Overweel, Topics relating to Netherlands New Guinea in Ternate Residency memoranda of transfer and other assorted documents. Leiden: DSALCUL, Jakarta: IRIS, 1995, x + 146 pp. [Irian Jaya Source Materials 13.] - Timothy P. Barnard, Daniel Perret, Sejarah Johor-Riau-Lingga sehingga 1914; Sebuah esei bibliografi. Kuala Lumpur: Kementerian Kebudayaan, Kesenian dan Pelancongan Malaysia/École Francaise d’Extrême Orient, 1998, 460 pp. - Peter Boomgaard, Om Prakash, European commercial enterprise in pre-colonial India. Cambridge: Cambridge University Press, 1998, xviii + 377 pp. [The New Cambridge History of India II-5.] - U.T. Bosma, Oliver Kortendick, Drei Schwestern und ihre Kinder; Rekonstruktion von Familiengeschichte und Identitätstransmission bei Indischen Nerlanders mit Hilfe computerunterstützter Inhaltsanalyse. Canterbury: Centre for Social Anthropology and Computing, University of Kent at Canterbury, 1996, viii + 218 pp. [Centre for Social Anthropology and Computing Monograph 12.] - Freek Colombijn, Thomas Psota, Waldgeister und Reisseelen; Die Revitalisierung von Ritualen zur Erhaltung der komplementären Produktion in SüdwestSumatra. Berlin: Reimer, 1996, 203 + 15 pp. [Berner Sumatraforschungen.] - Christine Dobbin, Ann Maxwell Hill, Merchants and migrants; Ethnicity and trade among Yunannese Chinese in Southeast Asia. New Haven: Yale University Southeast Asia Studies, 1998, vii + 178 pp. [Yale Southeast Asia Studies Monograph 47.] - Aone van Engelenhoven, Peter Bellwood, The Austronesians; Historical and comparative perspectives. Canberra: Department of Anthropology, Research School of Pacific and Asian Studies, Australian National University, 1995, viii + 359 pp., James J. Fox, Darrell Tryon (eds.) - Aone van Engelenhoven, Wyn D. Laidig, Descriptive studies of languages in Maluku, Part II. Jakarta: Badan Penyelenggara Seri NUSA and Universitas Katolik Indonesia Atma Jaya, 1995, xii + 112 pp. [NUSA Linguistic Studies of Indonesian and Other Languages in Indonesia 38.] - Ch. F. van Fraassen, R.Z. Leirissa, Halmahera Timur dan Raja Jailolo; Pergolakan sekitar Laut Seram awal abad 19. Jakarta: Balai Pustaka, 1996, xiv + 256 pp. - Frances Gouda, Denys Lombard, Rêver l’Asie; Exotisme et littérature coloniale aux Indes, an Indochine et en Insulinde. Paris: Éditions de l’École des Hautes Études en Sciences Sociales, 1993, 486 pp., Catherine Champion, Henri Chambert-Loir (eds.) - Hans Hägerdal, Timothy Lindsey, The romance of K’tut Tantri and Indonesia; Texts and scripts, history and identity. Kuala Lumpur: Oxford University Press, 1997, xix + 362 + 24 pp. - Renee Hagesteijn, Ina E. Slamet-Velsink, Emerging hierarchies; Processes of stratification and early state formation in the Indonesian archipelago: prehistory and the ethnographic present. Leiden: KITLV Press, 1995, ix + 279 pp. [VKI 166.] - David Henley, Victor T. King, Environmental challenges in South-East Asia. Richmond: Curzon Press, 1998, xviii + 410 pp. [Nordic Institute of Asian Studies, Man and Nature in Asia Series 2.] - C. de Jonge, Ton Otto, Cultural dynamics of religious change in Oceania. Leiden: KITLV Press, 1997, viii + 144 pp. [VKI 176.], Ad Boorsboom (eds.) - C. de Jonge, Chris Sugden, Seeking the Asian face of Jesus; A critical and comparative study of the practice and theology of Christian social witness in Indonesia and India between 1974 and 1996. Oxford: Regnum, 1997, xix + 496 pp. - John N. Miksic, Roy E. Jordaan, In praise of Prambanan; Dutch essays on the Loro Jonggrang temple complex. Leiden: KITLV Press, 1996, xii + 259 pp. [Translation Series 26.] - Marije Plomp, Ann Kumar, Illuminations; The writing traditions of Indonesia; Featuring manuscripts from the National Library of Indonesia. Jakarta: The Lontar Foundation, New York: Weatherhill, 1996., John H. McGlynn (eds.) - Susan de Roode, Eveline Ferretti, Cutting across the lands; An annotated bibliography on natural resource management and community development in Indonesia, the Philippines and Malaysia. Ithaca, New York: Cornell University Southeast Asia Program, 1997, 329 pp. [Southeast Asia Program Series 16.] - M.J.C. Schouten, Monika Schlicher, Portugal in Ost-Timor; Eine kritische Untersuchung zur portugiesischen Kolonialgeschichte in Ost-Timor, 1850 bis 1912. Hamburg: Abera-Verlag, 1996, 347 pp. - Karel Steenbrink, Leo Dubbeldam, Values and value education. The Hague: Centre for the Study of Education in Developing Countries (CESO), 1995, 183 pp. [CESO Paperback 25.] - Pamela J. Stewart, Michael Houseman, Naven or the other self; A relational approach to ritual action. Leiden: Brill, 1998, xvi + 325 pp., Carlo Severi (eds.) - Han F. Vermeulen, Pieter ter Keurs, The language of things; Studies in ethnocommunication; In honour of Professor Adrian A. Gerbrands. Leiden: Rijksmuseum voor Volkenkunde, 1990, 208 pp. [Mededelingen van het Rijksmuseum voor Volkenkunde 25.], Dirk Smidt (eds.)

All 224 consecutive new patients who were admitted in 1982 through 1985 to the day care department of a skilled-care psychogeriatric nursing home were followed longitudinally until death. Dementia was diagnosed in 95.1% of the 133 women and 91 men. Their mean age at admission was 78.7 years (SD = 7.4). Every 12 months after their initial attendance the patients' status was recorded and coded as living in the community, institutionalized or dead. At one year after initial attendance 99 (44.2%) patients still resided in the community, 94 (42.0%) were admitted to a nursing home or (psychiatric) hospital and 31 (13.8%) had died. At five years only nine (4.0%) patients resided in the community, 65 (29.0%) were in long-term institutional care and 150 (67.0%) had died. Age, gender, socioeconomic status or living alone did not contribute to first-year outcome, but severity of cognitive impairment was associated with an increased risk of becoming institutionalized. Using logistic regression analysis, a model of three variables, living at home, needing help from caregiving children, and high ratings of dependency, assigned 61.4% of 176 subjects correctly as institutionalized versus residing in the community.

Wild species in the Triticeae tribe are very valuable resources for agronomic improvement in cereal crop species. Intergeneric hybrids were produced between several barley cultivars and perennial species in the genera Elymus , Thinopyrum , and Pseudoroegneria . Caryopsis formation and subsequent plantlet regeneration from embryo culture were variable depending on the hybrid combinations. Chromosome numbers and hybrid identity were confirmed by GISH analysis on the somatic cells of the hybrids. While the hybrids showed very robust vegetative growth and exceeded the parental spikes in size, their floral morphologies resembled that of the wild species. Meiotic chromosome analysis revealed that the bivalent formation frequency per cell ranged from 0.06 in Hordeum vulgare ‘Betzes’ × Elymus curvatus to 3.0 in Elymus humidus × H. vulgare ‘Manley’. By GISH analysis on the meiocytes of the hybrid E. humidus × ‘Manley’, the frequency of autosyndetic bivalents exceeded the allosyndetic bivalent formation, which gave an insight into the genome constitution of E. humidus as an autoallohexploid species. Regardless of the low allosyndetic chromosome pairing between barley and E. humidus, this combination may be useful for further input, since E. humidus is known to carry many valuable genes for biotic and abiotic stress tolerance.

To evaluate the efficacy and safty of the humanized anti-epidermal factor receptor monoclonal antibody h-R3 in combination with radiotherapy for locoregionally advanced nasopharyngeal carcinoma.Totally, 137 patients from 7 medical center around China were randomly divided into combined therapy group or control group. There was no difference in Karnofsky performance score between two groups. All patients in both groups received radical conventionally fractionated radiotherapy to the total dose of D(T) 70-76 Gy. For the combined therapy group, h-R3 was added at a dose of 100 mg i.v. weekly for 8 weeks started at the beginning of radiotherapy.Of the 137 eligilbe patients, 70 were in the combined therapy group treated by h-R3 plus radiotherapy and 67 in the control group by radiotherapy alone. The intent-to-treat (ITT) population consisted of 130 patients, while the per-protocol (PP) population was composed of 126 patients. The efficacy was assessed respectively at three point of time: the end of treatment, the 5th- and 17th-week after treatment. The complete response (CR) of the combined therapy group was significantly higher than that of the control group in both ITT and PP (ITT: 65.63%, 87.50%, 90.63% versus 27.27%, 42.42%, 51.52%; PP: 67.21%, 90.16%, 93.44% versus 27.69%, 43.08%, 52.31%; P0.05, respectively). The most common h-R3-related adverse reactions were fever (4.3%), hypotension (2.9%), nausea (1.4%), dizziness (2.9%) and rash (1.4%), which could be reversible if treated properly. Radiotherapy combined with 100 mg h-R3 i. v. weekly was tolerable and did not aggravate the side effects of radiation. The quality of life in the combined therapy group was comparable to that in the control group.This phase 1 multicenter clinical trial shows that h-R3 in combination with radiotherapy is effective and well-tolerated for the treatment of locoregionally advanced nasopharyngeal carcinoma.

Two methods for calculating the power density input to structures excited by turbulent flow were developed and used to predict the average response of the structure. The input power density was calculated using the cross-spectral density of the random fluctuating pressure loading on the structure. The energy response of structures excited by distributed loading was obtained using the energy flow analysis method. Both methods for calculating the input power density and the method for calculating the energy density response were verified for beams and plates using classical modal analysis.

SUMMARY This case study reports the profile of preserved and impaired capacities in a left-handed patient suffering from primary degenerative dementia of unknown aetiology. She was remarkable because her relatively preserved object naming and semantic categorization abilities contrasted with severe deficits in speech fluency, oral reading, inability to execute spoken and written commands, and severely impaired auditory-verbal short-term memory. Her reading disorder could be characterized as a disturbance of assembled phonology. She had great difficulty reading pronounceable nonwords, but she could correctly read irregular words. She showed effects of word imageability or concreteness (more than word frequency). She also showed effects of part-of-speech, where nouns and adjectives were read more easily than inflected verbs. She had difficulty reading function words. The syntactic category effects could be proven (by hierarchical log-linear analysis) not to be an artefact of imageability differences between verbs, adjectives and nouns. In reading aloud she made visual and morphological errors, but no semantic errors. This interesting pattern of preserved semantic information and disrupted phonological processing is unusual in dementia and contrasts with the severe dysnomia of patients with surface dyslexia who are able to read by the indirect, assembly-of-phonology route and show better reading of nonwords than irregular words. Her reading by a direct visual-semantic route appeared to be associated with relatively intact object naming, concrete word reading, and irregular word reading, This selective impairment of phonological reading in the context of partly preserved semantic abilities was interpreted as confirmation of the dissociability of language functions in primary degenerative dementia.

Rocks and constituent minerals of the Meguma Group from southeastern Nova Scotia were analyzed for gold. By far the highest levels (4311 ng/g = ppb, whole rocks (1.0 ppb) and other minerals (

Based on developments within cognitive psychology, this paper reviews the concepts of experience and of methodology. Cognitive psychology has brought back the old Kantian theme that our ways of cognizing or perceiving the human world (environment) are permeated by our ways of thinking or conceptualizing (about it). The conceptual relativity of experience implies that experience - the touchstone of empirical science - is to some extent not independent of the researcher. This conclusion calls for the construction of a generalized or relativized methodology and epistemology. To that aim, the conventional view on methodology, according to which it outhnes methods to acquire knowledge, is abandoned and an alternative view is adopted which outlines methods for clarifying confusion and for eliminating ignorance. The relativized methodology is based not on a theory of knowledge but on a particular anepistemology , a theory of ignorance and confusion.

A series of analytical and experimental studies have been conducted at the Paul Scherrer Institut (PSI) to investigate particulate flows inside a model containment consisting of a differentially heated cubical cavity (DHC). Lately, LES simulations were performed using the finite volume ANSYS Fluent CFD code at Rayleigh number 109. After initial confrontation of the predicted fluid field against experimental data, it was concluded that important physical phenomena had not been accounted for in the original pre-test simulations. Namely, radiation and wall conduction in the test section were not negligible and contributed to producing a fluid field that departed in significant ways from that obtained assuming idealized boundary conditions. We show hereafter that the LES predictions with realistic boundary conditions, including radiation and conduction, are in good overall agreement with the experimental mean velocity and temperature fields. In particular, we show that radiation increases turbulence, which in turn increases mixing and reduces the thermal stratification in the cavity. We also find that the velocity rms peaks near the vertical walls are well captured with the realistic boundary conditions (typically within 30%), in contrast to the previous ideal simulations which miss these peaks by a factor 3 to 4