1. Angiotensin receptors in GtoPdb v.2023.1
- Author
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Patrick Vanderheyden, Thomas Unger, Hamiyet Unal, Kalyan Tirupula, Pieter B. M. W. M. Timmermans, Walter G. Thomas, Jacqueline Kemp, Sadashiva Karnik, Tadashi Inagami, Ahsan Husain, László Hunyady, Mastgugu Horiuchi, Theodore L. Goodfriend, Emanuel Escher, Satoru Eguchi, Khuraijam Dhanachandra Singh, Marc De Gasparo, Kevin J. Catt, Kenneth E. Bernstein, and Wayne Alexander
- Subjects
General Medicine ,General Chemistry - Abstract
The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotensin receptors [63, 155]), which have around 30% sequence similarity. The decapeptide angiotensin I, the octapeptide angiotensin II and the heptapeptide angiotensin III are endogenous ligands. losartan, candesartan, olmesartan, telmisartan, etc. are clinically used AT1 receptor blockers.
- Published
- 2023