1. Initial Clinical Experiences With Novel Diagonal ECLS System in Pediatric Cardiac Patients
- Author
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Haydin Sertac, Guzeltas Alper, Altin H. Firat, Ayyildiz Pelin, Onan I. Selen, Ozturk Erkut, Kasar Taner, Cine Nihat, Yildiz Okan, and Erkan Halime
- Subjects
endocrine system ,medicine.medical_specialty ,medicine.medical_treatment ,0206 medical engineering ,Biomedical Engineering ,Medicine (miscellaneous) ,Bioengineering ,02 engineering and technology ,030204 cardiovascular system & hematology ,Extracorporeal ,Biomaterials ,03 medical and health sciences ,0302 clinical medicine ,Statistical significance ,Hospital discharge ,medicine ,Extracorporeal membrane oxygenation ,Weaning ,Complication rate ,business.industry ,General Medicine ,020601 biomedical engineering ,Cardiac surgery ,Surgery ,Life support ,business - Abstract
Extracorporeal life support (ECLS) provides mechanical support following cardiac surgery when respiratory or cardiac failure occurs. The aim of this study was to analyze the safety and feasibility of the Medos Deltastream diagonal pump (DP3) ECLS system in pediatric cardiac patients. We described the technical considerations and risk factors related to the survival outcomes in 102 pediatric cardiac patients who received ECLS support between March 2011 and April 2016. We switched from the DP2 system, which was used for the initial 25 patients, to the DP3 system after November 2012. The DP3 was then used in a consecutive series of 77 patients (4.5% of all pediatric patients who underwent congenital heart surgery during the same time period). The patients' median age was 90 days (range: 2 days-12 years), while their median weight was 4 kg (range: 2.1-40 kg). Fifty four patients (70%) were weaned off ECLS, while 28 patients (36.3%) were successfully discharged from the hospital by means of the DP3 system. The median ECLS duration for survivors was 8.2 days (range: 4-14.5 days). The ECLS indications, durations, and initiation times had no statistical significance in terms of survival. Renal, hemorrhagic, and neurologic complications were all associated with decreased hospital discharge rates (P = 0.003, P = 0.045, and P
- Published
- 2017