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Additional file 1: Table S1. Primers sequence of genes for RT-qPCR.

Additional file 3: Table S3. RT-qPCR analysis of selected genes.

Additional file 4: Table S4. Specific growth rates of mutants in the presence of 0 (control), 3, 5, 10 and 15 mM of p-CA.

Additional file 1: Figure S1 Growth kinetics of strains W3110, WG, WGM, WGMC, and WHIC. Glucose concentration (triangles), biomass concentration (squares) and acetate concentration (diamonds).

Additional file 3: Supplementary table 1 Primers used in this study.

Response surfaces and contour plots for all fluxes. Description: Response surfaces and contour plots for all reactions detailed on the metabolic network for initial exponential, mid exponential and mid stationary fermentation stages. (PDF 25,629 kb)

Strains, plasmids and oligonucleotides used on this work, AR36 poxB− figures. Description: Table for all plasmids and oligonucleotides used. AR36 ΔpoxB strain construction. Fermentation profiles for AR36 ΔpoxB and AR36 on highly concentrated substrate media. (PDF 215 kb)

Model and validation data, parameters and statistical values. Description: Parameters and statistical value tables for physiological models. Response surface parameters and statistical values for the polynomial approximation. Response surface prediction validation data. Response surface critical points calculations. Dynamic Flux models parameters and statistics. (PDF 186 kb)