Search

Your search keyword '"Girardi F."' showing total 17 results
Start Over Author "Girardi F." Language undetermined
17 results on '"Girardi F."'

1. Survival after neoadjuvant therapy with trastuzumab-lapatinib and chemotherapy in patients with HER2-positive early breast cancer: a meta-analysis of randomized trials

Author

Guarneri, V, Griguolo, G, Miglietta, F, Conte, P F, Dieci, M V, and Girardi, F

Subjects
neoadjuvant treatment, Receptor, ErbB-2, Breast Neoplasms, Lapatinib, Trastuzumab, Hormones, Neoadjuvant Therapy, meta-analysis, Antineoplastic Combined Chemotherapy Protocols, Humans, Female, Neoplasm Recurrence, Local, HER2-positive breast cancer, HER2-positive breast cancer, neoadjuvant treatment, lapatinib, trastuzumab, meta-analysis, Randomized Controlled Trials as Topic
Abstract

Studies testing the addition of lapatinib to neoadjuvant trastuzumab + chemotherapy reported an increase in pathologic complete response (pCR), with, nevertheless, discordant results in terms of survival, mainly due to suboptimal power. We here leverage the meta-analytic approach to resolve these inconsistencies.We conducted a meta-analysis of randomized phase II/III studies testing lapatinib + trastuzumab in combination with neoadjuvant chemotherapy for human epidermal growth factor receptor (HER2)-positive early breast cancer (BC). Recurrence-free survival (RFS) and overall survival (OS) were adopted as survival endpoints. Pooled hazard ratios (HR) were obtained for the effect of lapatinib + trastuzumab versus trastuzumab, pCR versus no-pCR in the whole study populations and pCR versus no-pCR according to hormone receptor status.Four phase II/III randomized trials were included in the meta-analysis (CALGB 40601, Cher-LOB, NSABP-B41, NeoALTTO) for an overall population of 1410 patients receiving neoadjuvant chemotherapy in association with either trastuzumab, lapatinib or their combination. RFS was significantly improved with dual HER2 blockade as compared to trastuzumab [HR 0.62, 95% confidence interval (CI) 0.46-0.85]. Dual blockade also led to significantly improved OS (HR 0.65, 95% CI 0.43-0.98). For all treatments combined, patients achieving pCR had better RFS and OS than those with residual disease (HR 0.45, 95% CI 0.34-0.60, and HR 0.32, 95% CI 0.22-0.48, for RFS and OS, respectively). In patients with hormone receptor-negative tumors, pCR was associated with 65% and 73% relative reduction of risk of relapse and death, respectively. Patients with hormone receptor-positive tumors also experienced improved RFS if they achieved pCR; however, the benefit was smaller than that in hormone receptor-negative disease.Findings from this meta-analysis further validate the role of pCR as a strong predictor of outcome in patients with HER2-positive BC, especially in hormone receptor-negative disease. Moreover, we provide robust evidence that dual blockade with lapatinib + trastuzumab in combination with neoadjuvant chemotherapy prolongs OS, suggesting that the role of lapatinib could be reconsidered in the early setting.

Published
2021

2. Global surveillance of survival from intrinsic brain tumours diagnosed during 2000-2014: trends by age and histology

Author

Girardi, F, Allemani, C, and Coleman, MP

Abstract

This thesis provides a comprehensive examination of world-wide variation in population-based survival from brain tumours in children and adults, by histology. It comprises five chapters in the form of research papers. Population-based cancer survival estimates are key to assessing the overall effectiveness of a health care system in managing cancer. The third cycle of the CONCORD programme for the global surveillance of cancer survival (CONCORD-3), which included data for more than 37.5 million cancer patients diagnosed during 2000-2014, highlighted substantial world-wide disparities in survival for all brain tumours combined, in both children and adults. Survival comparisons for all brain tumours combined, however, are potentially confounded by international variation in histology distribution and the clinical heterogeneity of the various tumour subtypes. Robust comparisons of brain tumour survival require clinically relevant data by histology because histology is the main outcome predictor. Granular survival estimates by histology are therefore warranted. The first and second chapters, two systematic reviews, appraise the geographical coverage and methodology of studies of brain tumour survival by histology. The first chapter focusses on children, while the second centres on adolescents and young adults. Adolescents and young adults are a transitional age group for which the strategy for presenting epidemiological data by histology is still debated. These reviews show that very little is known about brain tumour survival by histology beyond Europe and North America, and that differences in study design may indeed hamper robust comparisons. The two systematic reviews inform the scope of the third chapter, in which distinct histology groupings for children and adults are defined. The groupings for children represent an enhanced version of the International Classification of Childhood Cancer (third edition), while those for adults are designed to produce clinically meaningful categories. These groupings schemes form the basis for an examination of the global variation in the histology distribution of brain tumours and for an account of some of the key quality indicators for cancer registration. 7 The histology distribution of brain tumours varied widely world-wide (2000- 2014). In children, the proportion of low-grade astrocytic tumours ranged from less than 10% to more than 30%. In adults, the proportion of glioblastoma varied between 9% and 69%. International comparisons were made difficult by wide differences in the proportion of tumours of unspecified histology, which accounted for up to 52% of diagnoses in children and up to 65% in adults. These histology groupings are then used to produce up-to-date analyses of global trends in brain tumour survival by histology, for children (chapter 4) and adults (chapter 5), using individual records from CONCORD-3 for 610,710 patients diagnosed with a brain tumour during 2000-2014 in 60 countries. Many of these countries have never previously been included in studies of brain tumour survival by histology. The studies deploy the same protocol for data collection, quality control and statistical methods for all the data sets. Brain tumour survival in children and adults were examined in two separate analyses. Five-year net survival for low-grade astrocytoma in children was in the range 84-100%, while it varied between 47% and 86% for medulloblastoma. In adults, survival from glioblastoma improved substantially after 2005 in most countries, mainly in the short term (up to two years from diagnosis). The increase in two-year survival between 2000-2004 and 2010-2014 was more remarkable for adults aged 40-70 years than for younger patients (15-39 years). Trends for 2000-2014 were upward for the 40-70 age group, while they were somewhat flat for the 15-39 age group. To our knowledge, this is the largest study of population-based survival from brain tumours by histology. The geographical breadth, the methodology for data collection and analysis, and the proposed histology groupings are expected to set a benchmark for future global comparisons.

Published
2021
Full Text
View/download PDF

3. First-line antiretroviral therapy with efavirenz plus tenofovir disiproxil fumarate/emtricitabine or rilpivirine plus tenofovir disiproxil fumarate/emtricitabine: a durability comparison

Author

Taramasso, L., Biagio, Di, Maggiolo, A., Tavelli, F., Lo Caputo, A., Bonora, S., Zaccarelli, S., Caramello, M., Costantini, P., Viscoli, A., D'Arminio, Monforte, Cozzi-Lepri, A., Andreoni, A., Angarano, M., Antinori, G., Castelli, A., Cauda, F., Perri, Di, Galli, G., Iardino, M., Ippolito, R., Lazzarin, G., Perno, A., C. F., Von, Schloesser, Viale, F., Castagna, P., Ceccherini-Silberstein, A., Girardi, F., Mussini, E., Puoti, C., Ammassari, M., Balotta, A., Bandera, C., Bonfanti, A, Borderi, P., Calcagno, M., Calza, A., Capobianchi, L., Cingolani, M. R., Cinque, A., Luca, De, Gianotti, A., Gori, N., Guaraldi, A., Lapadula, G., Lichtner, G., Madeddu, M., Marchetti, G., Marcotullio, G., Monno, S., Nozza, L., Quiros, Roldan, Rossotti, E., Rusconi, R., Santoro, S., Saracino, M. M., Fanti, A., Galli, I., Lorenzini, L, Rodano, P., Shanyinde, A., Carletti, M., Carrara, F., Caro, Di, Graziano, S., Petrone, F., Prota, G, Quartu, S., Truffa, S., Giacometti, A., Valeriani, C., Santoro, C., Suardi, C., Donati, V., Verucchi, G., Minardi, C., Quirino, T., Abeli, C., Manconi, P. E., Piano, P., Cacopardo, B., Celesia, B., Vecchiet, J., Falasca, K., Sighinolfi, L., Segala, D., Mazzotta, F., Vichi, F., Cassola, G., Alessandrini, A., Bobbio, N., Mazzarello, G., Mastroianni, C., Belvisi, V., Caramma, I., Chiodera, A., Castelli, A. P., Rizzardini, G., Ridolfo, A. L., Piolini, R., Salpietro, S., Carenzi, L., Moioli, M. C., Tincati, C., Puzzolante, C., Abrescia, N., Chirianni, A., Borgia, G., Di Martino, F., Maddaloni, L., Gentile, I., Orlando, R., Baldelli, F., Francisci, D., Parruti, G., Ursini, T., Magnani, G., Ursitti, M. A., Vullo, V., Cristaudo, A., Baldin, G., Cicalini, S., Gallo, L., Nicastri, E., Acinapura, R., Capozzi, M., Libertone, R., Savinelli, S., Latini, A., Cecchetto, M., Viviani, F., Mura, M. S., Rossetti, B., Orofino, G. C., Sciandra, M., Bassetti, M., Londero, A., Pellizzer, G., Manfrin, V., Taramasso, L, Di Biagio, A, Maggiolo, F, Tavelli, A, Lo Caputo, S, Bonora, S., Zaccarelli, M, Caramello, P, Costantini, A, Viscoli, C., d'Arminio Monforte, A, Cozzi-Lepri, A, on behalf of the Italian Cohort NaiveAntiretrovirals (ICONA) Foundation Study, Group, Castagna, A, Taramasso, L., Di Biagio, A., Maggiolo, F., Tavelli, A., Lo Caputo, S., Zaccarelli, M., Caramello, P., Costantini, A., d'Arminio Monforte, A., Cozzi-Lepri, A., Andreoni, M., Angarano, G., Antinori, A., Castelli, F., Cauda, R., Di Perri, G., Galli, M., Iardino, R., Ippolito, G., Lazzarin, A., Perno, C.F., von Schloesser, F., Viale, P., Castagna, A., Ceccherini-Silberstein, F., Girardi, E., Mussini, C., Puoti, M., Ammassari, A., Balotta, C., Bandera, A., Bonfanti, P., Borderi, M., Calcagno, A., Calza, L., Capobianchi, M.R., Cingolani, A., Cinque, P., De Luca, A., Gianotti, N., Gori, A., Guaraldi, G., Lapadula, G., Lichtner, M., Madeddu, G., Marchetti, G., Marcotullio, S., Monno, L., Nozza, S., Quiros Roldan, E., Rossotti, R., Rusconi, S., Santoro, M.M., Saracino, A., Fanti, I., Galli, L., Lorenzini, P., Rodano, A., Shanyinde, M., Carletti, F., Carrara, S., Di Caro, A., Graziano, S., Petrone, F., Prota, G., Quartu, S., Truffa, S., Giacometti, A., Valeriani, C., Santoro, C., Suardi, C., Donati, V., Verucchi, G., Minardi, C., Quirino, T., Abeli, C., Manconi, P.E., Piano, P., Cacopardo, B., Celesia, B., Vecchiet, J., Falasca, K., Sighinolfi, L., Segala, D., Mazzotta, F., Vichi, F., Cassola, G., Alessandrini, A., Bobbio, N., Mazzarello, G., Mastroianni, C., Belvisi, V., Caramma, I., Chiodera, A., Castelli, A.P., Rizzardini, G., Ridolfo, A.L., Piolini, R., Salpietro, S., Carenzi, L., Moioli, M.C., Tincati, C., Puzzolante, C., Abrescia, N., Chirianni, A., Borgia, G., Di Martino, F., Maddaloni, L., Gentile, I., Orlando, R., Baldelli, F., Francisci, D., Parruti, G., Ursini, T., Magnani, G., Ursitti, M.A., Vullo, V., Cristaudo, A., Baldin, G., Cicalini, S., Gallo, L., Nicastri, E., Acinapura, R., Capozzi, M., Libertone, R., Savinelli, S., Latini, A., Cecchetto, M., Viviani, F., Mura, M.S., Rossetti, B., Orofino, G.C., Sciandra, M., Bassetti, M., Londero, A., Pellizzer, G., Manfrin, V., Bonora, S, Viscoli, C, Andreoni, M, Angarano, G, Antinori, A, Castelli, F, Cauda, R, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Perno, C, von Schloesser, F, Viale, P, Ceccherini-Silberstein, F, Girardi, E, Mussini, C, Puoti, M, Ammassari, A, Balotta, C, Bandera, A, Bonfanti, P, Borderi, M, Calcagno, A, Calza, L, Capobianchi, M, Cingolani, A, Cinque, P, De Luca, A, Gianotti, N, Gori, A, Guaraldi, G, Lapadula, G, Lichtner, M, Madeddu, G, Marchetti, G, Marcotullio, S, Monno, L, Nozza, S, Quiros Roldan, E, Rossotti, R, Rusconi, S, Santoro, M, Saracino, A, Fanti, I, Galli, L, Lorenzini, P, Rodano, A, Shanyinde, M, Carletti, F, Carrara, S, Di Caro, A, Graziano, S, Petrone, F, Prota, G, Quartu, S, Truffa, S, Giacometti, A, Valeriani, C, Santoro, C, Suardi, C, Donati, V, Verucchi, G, Minardi, C, Quirino, T, Abeli, C, Manconi, P, Piano, P, Cacopardo, B, Celesia, B, Vecchiet, J, Falasca, K, Sighinolfi, L, Segala, D, Mazzotta, F, Vichi, F, Cassola, G, Alessandrini, A, Bobbio, N, Mazzarello, G, Mastroianni, C, Belvisi, V, Caramma, I, Chiodera, A, Castelli, A, Rizzardini, G, Ridolfo, A, Piolini, R, Salpietro, S, Carenzi, L, Moioli, M, Tincati, C, Puzzolante, C, Abrescia, N, Chirianni, A, Borgia, G, Di Martino, F, Maddaloni, L, Gentile, I, Orlando, R, Baldelli, F, Francisci, D, Parruti, G, Ursini, T, Magnani, G, Ursitti, M, Vullo, V, Cristaudo, A, Baldin, G, Cicalini, S, Gallo, L, Nicastri, E, Acinapura, R, Capozzi, M, Libertone, R, Savinelli, S, Latini, A, Cecchetto, M, Viviani, F, Mura, M, Rossetti, B, Orofino, G, Sciandra, M, Bassetti, M, Londero, A, Pellizzer, G, Manfrin, V, Perno, C. F., Capobianchi, M. R., Santoro, M. M., Manconi, P. E., Castelli, A. P., Ridolfo, A. L., Moioli, M. C., Ursitti, M. A., Mura, M. S., and Orofino, G. C.

Subjects
0301 basic medicine, medicine.medical_specialty, Efavirenz, combination antiretroviral therapy, durability, efavirenz, naïve, rilpivirine, Health Policy, Infectious Diseases, Pharmacology (medical), Infectious Disease, Emtricitabine, Gastroenterology, NO, 03 medical and health sciences, chemistry.chemical_compound, Interquartile range, Internal medicine, medicine, business.industry, 030112 virology, Confidence interval, Discontinuation, naive, Regimen, chemistry, combination antiretroviral therapy, durability, efavirenz, naïve, rilpivirine, Rilpivirine, business, Viral load, medicine.drug
Abstract

Objectives: The aim of this study was to compare the durabilities of efavirenz (EFV) and rilpivirine (RPV) in combination with tenofovir/emtricitabine (TDF/FTC) in first-line regimens. Methods: A multicentre prospective and observational study was carried out. We included all patients participating in the Italian Cohort Naive Antiretrovirals (ICONA) Foundation Study who started first-line combination antiretroviral therapy (cART) with TDF/FTC in combination with RPV or EFV, with a baseline viral load < 100 000 HIV-1 RNA copies/mL. Survival analyses using Kaplan–Meier (KM) curves and Cox regression with time-fixed covariates at baseline were employed. Results: Overall, 1490 ART-naïve patients were included in the study, of whom 704 were initiating their first cART with EFV and 786 with RPV. Patients treated with EFV, compared with those on RPV, were older [median 36 (interquartile range (IQR) 30–43) years vs. 33 (IQR 27–39) years, respectively; P < 0.001], were more frequently at Centers for Disease Control and Prevention (CDC) stage C (3.1% vs. 1.4%, respectively; P = 0.024), and had a lower median baseline CD4 count [340 (IQR 257–421) cells/μL vs. 447 (IQR 347–580) cells/μL, respectively; P < 0.001] and a higher median viral load [4.38 (IQR 3.92–4.74) log10 copies/mL vs. 4.23 (IQR 3.81–4.59) log10 copies/mL, respectively], (P = 0.004). A total of 343 patients discontinued at least one drug of those included in the first cART regimen, more often EFV (26%) than RPV (13%), by 2 years (P < 0.0001). After adjustment, patients treated with EFV were more likely to discontinue at least one drug for any cause [relative hazard (RH) 4.09; 95% confidence interval (CI) 2.89–5.80], for toxicity (RH 2.23; 95% CI 1.05–4.73) for intolerance (RH 5.17; 95% CI 2.66–10.07) and for proactive switch (RH 10.96; 95% CI 3.17–37.87) than those starting RPV. Conclusions: In our nonrandomized comparison, RPV was better tolerated, less toxic and showed longer durability than EFV, without a significant difference in rates of discontinuation because of failures.

Published
2018

4. Sardinia Radio Telescope observations of Abell 194

Author

F. Govoni, M. Murgia, V. Vacca, F. Loi, M. Girardi, F. Gastaldello, G. Giovannini, L. Feretti, R. Paladino, E. Carretti, R. Concu, A. Melis, S. Poppi, G. Valente, G. Bernardi, A. Bonafede, W. Boschin, M. Brienza, T. E. Clarke, S. Colafrancesco, F. de Gasperin, D. Eckert, T. A. Enßlin, C. Ferrari, L. Gregorini, M. Johnston-Hollitt, H. Junklewitz, E. Orrù, P. Parma, R. Perley, M. Rossetti, G. B Ta

Published
2017
Full Text
View/download PDF

7. Ricerche Sperimentali Sull'effetto Anticellulare di Alcune Associazioni di Antimitotici su Elementi Proliferanti in Vitro

Author

Musolino G, Girardi F, Tortarolo E, and Lenti G

Subjects
Drug, Deacetylcolchicine, Cancer Research, Oncology, Chemistry, media_common.quotation_subject, Cytostatic agents, Cytotoxic T cell, General Medicine, Pharmacology, Experimental research, In vitro, media_common
Abstract

The action of some associations of cytostatic agents on « in vitro » embryonic cells are studied: chloramine, deacetylcolchicine and 6-mercapto-purine added with hydrocortisone, and 6-mercapto-purine plus chloramine. The effective doses of each drug were always remarkably lower than those wich were found to have the minimal action in previous researches. It is so demonstrated that this association potentiates the activity of the single drugs. The enhancement varies as for the type and intensity in the different experimented associations. The possibility of a therapeutical application of the cytotoxic combinations is discussed.

Published
1957

12. Alcohol-addiction inpatient: Characteristics of patients and rehabilitation program | La residenzialità alcologica ospedaliera: Caratteristiche dei pazienti e dei percorsi terapeutici/riabilitativi

Author

Antonella Zambon, Pinto, S. P. S., Agostini, D., Aliotta, F., Biondini, F., Bizzi, P., Cerizza, G., Dattola, A., Forghieri, M., Giorgi, I., Girardi, F., Hinnenthal, I. M., Sodano, A. J., Liberto, L., Majolino, E., Mioni, D., Movalli, M., Pedretti, L., Propato, A., Spolaor, G., Vizzuso, P., Zucchi, G., and Vittadini, G.

13. Unmasking the prevalence of amyloid cardiomyopathy in the real world: results from Phase 2 of the AC-TIVE study, an Italian nationwide survey

Author

Marco Merlo, Linda Pagura, Aldostefano Porcari, Matteo Cameli, Giuseppe Vergaro, Beatrice Musumeci, Elena Biagini, Marco Canepa, Lia Crotti, Massimo Imazio, Cinzia Forleo, Francesco Cappelli, Federico Perfetto, Stefano Favale, Gianluca Di Bella, Franca Dore, Francesca Girardi, Daniela Tomasoni, Rita Pavasini, Valeria Rella, Giuseppe Palmiero, Martina Caiazza, Maria Cristina Carella, Andrea Igoren Guaricci, Giovanna Branzi, Angelo Giuseppe Caponetti, Giulia Saturi, Giovanni La Malfa, Andrea Carlo Merlo, Alessandro Andreis, Francesco Bruno, Francesca Longo, Maddalena Rossi, Guerino Giuseppe Varrà, Riccardo Saro, Luca Di Ienno, Giuseppe De Carli, Elisa Giacomin, Chiara Arzilli, Giuseppe Limongelli, Camillo Autore, Iacopo Olivotto, Luigi Badano, Gianfranco Parati, Stefano Perlini, Marco Metra, Michele Emdin, Claudio Rapezzi, Gianfranco Sinagra, Merlo, Marco, Pagura, Linda, Porcari, Aldostefano, Cameli, Matteo, Vergaro, Giuseppe, Musumeci, Beatrice, Biagini, Elena, Canepa, Marco, Crotti, Lia, Imazio, Massimo, Forleo, Cinzia, Cappelli, Francesco, Perfetto, Federico, Favale, Stefano, Di Bella, Gianluca, Dore, Franca, Girardi, Francesca, Tomasoni, Daniela, Pavasini, Rita, Rella, Valeria, Palmiero, Giuseppe, Caiazza, Martina, Carella, Maria Cristina, Igoren Guaricci, Andrea, Branzi, Giovanna, Caponetti, Angelo Giuseppe, Saturi, Giulia, La Malfa, Giovanni, Merlo, Andrea Carlo, Andreis, Alessandro, Bruno, Francesco, Longo, Francesca, Rossi, Maddalena, Varrà, Guerino Giuseppe, Saro, Riccardo, Di Ienno, Luca, De Carli, Giuseppe, Giacomin, Elisa, Arzilli, Chiara, Limongelli, Giuseppe, Autore, Camillo, Olivotto, Iacopo, Badano, Luigi, Parati, Gianfranco, Perlini, Stefano, Metra, Marco, Emdin, Michele, Rapezzi, Claudio, Sinagra, Gianfranco, Merlo, M, Pagura, L, Porcari, A, Cameli, M, Vergaro, G, Musumeci, B, Biagini, E, Canepa, M, Crotti, L, Imazio, M, Forleo, C, Cappelli, F, Perfetto, F, Favale, S, Di Bella, G, Dore, F, Girardi, F, Tomasoni, D, Pavasini, R, Rella, V, Palmiero, G, Caiazza, M, Carella, M, Igoren Guaricci, A, Branzi, G, Caponetti, A, Saturi, G, La Malfa, G, Merlo, A, Andreis, A, Bruno, F, Longo, F, Rossi, M, Varra, G, Saro, R, Di Ienno, L, De Carli, G, Giacomin, E, Arzilli, C, Limongelli, G, Autore, C, Olivotto, I, Badano, L, Parati, G, Perlini, S, Metra, M, Emdin, M, Rapezzi, C, Sinagra, G, and Michele, Emdin

Subjects
Amyloid cardiomyopathy, Echocardiography, Epidemiology, Light chain amyloidosis, Red flags, Transthyretin amyloidosis, Heart Failure, Left, Stroke Volume, Amyloidosis, Middle Aged, Ventricular Function, Left, Humans, Prevalence, Prospective Studies, Cardiomyopathies, Ventricular Function, Light chain amyloidosi, Red flag, Cardiology and Cardiovascular Medicine
Abstract

Aim: To investigate the prevalence of amyloid cardiomyopathy (AC) and the diagnostic accuracy of echocardiographic red flags of AC among consecutive adult patients undergoing transthoracic echocardiogram for reason other than AC in 13 Italian institutions. Methods and results: This is an Italian prospective multicentre study, involving a clinical and instrumental work-up to assess AC prevalence among patients ≥55 years old with an echocardiogram suggestive of AC (i.e. at least one echocardiographic red flag of AC in hypertrophic, non-dilated left ventricles with preserved ejection fraction). The study was registered at ClinicalTrials.gov (NCT04738266). Overall, 381 patients with an echocardiogram suggestive of AC were identified among a cohort of 5315 screened subjects, and 217 patients completed the investigations. A final diagnosis of AC was made in 62 patients with an estimated prevalence of 29% (95% confidence interval 23%–35%). Transthyretin-related AC (ATTR-AC) was diagnosed in 51 and light chain-related AC (AL-AC) in 11 patients. Either apical sparing or a combination of ≥2 other echocardiographic red flags, excluding interatrial septum thickness, provided a diagnostic accuracy >70%. Conclusion: In a cohort of consecutive adults with echocardiographic findings suggestive of AC and preserved left ventricular ejection fraction, the prevalence of AC (either ATTR or AL) was 29%. Easily available echocardiographic red flags, when combined together, demonstrated good diagnostic accuracy.

Published
2022

14. Impact of Overlithiation and Al doping on the battery performance of Li-rich layered oxide materials

Author

A. Celeste, F. Girardi, L. Gigli, V. Pellegrini, L. Silvestri, S. Brutti, Celeste, A., Girardi, F., Gigli, L., Pellegrini, V., Silvestri, L., and Brutti, S.

Subjects
General Chemical Engineering, Synchrotron techniques, Raman spectroscopy, Electrochemistry, Lithium-rich layered oxides, Doping, Li-ion batteries, Lithium-rich layered oxides, Li-ion batteries, Synchrotron techniques, Doping, Raman spectroscopy, synchrotron techniques, doping
Abstract

Lithium rich layered oxides (LRLOs) are one of the best alternatives for the next generation positive electrodes materials for Li-ion batteries. However, LRLOs suffer a remarkable voltage decay upon cycling that prevents stable and prolonged electrochemical performances and contains large quantities of cobalt in the transition metal blend. Here, we demonstrate the performance in batteries of a series of innovative materials with general formula Li1.2+xMn0.54Ni0.13Co0.13-x-yAlyO2 (where 0.03≤x ≤ 0.08 and 0.03≤y ≤ 0.05) capable to supply large reversible specific capacities (around 200 mAh g−1), stable cycling performance with reduced voltage decay. This communication sheds light on the interplay between structural and electronic disorder induced by Al/Li co-doping in LRLO and the corresponding functional properties in batteries. The impact of substitution of cobalt by Li and Al co-doping on the structural and morphological properties has been examined by Synchrotron X-ray diffraction (XRD), microwave plasma atomic emission spectrometer (MP-AES) and scanning electron microscopy (SEM). Furthermore, to better understand the structure-function interplay of these over-lithiated materials, ex situ analyses are here reported coupling Synchrotron X-Ray diffraction and Raman Spectroscopy. Based on the obtained results, we proved that coupling the over-lithiation with the aluminum doping, is an effective strategy to reduce the cobalt content into the LRLOs structure maintaining high electrochemical performance. Beside the values of specific capacities obtained in lithium cells, these materials exhibit excellent capacity retention and voltage retention, in particular for the material with the smallest content of cobalt, i.e. Li1.28Mn0.54Ni0.13Co0.02Al0.03O2. Furthermore, thanks to the ex-situ analysis of the latter, we explained the structural evolution of the sample upon cycling that showed the formation of a secondary trigonal phase and the occurrence of limited local distortions of layered structure.

Published
2022

15. Prevalence of Polysubstance Abuse and Dual Diagnosis in Patients Admitted to Alcohol Rehabilitation Units for Alcohol-Related Problems in Italy: Changes in 15 Years

Author

Cristina Airoldi, G Cerizza, L Pedretti, G Spolaor, A Dattola, G Vittadini, P Bizzi, P Ranaletti, D Agostini, Antonella Zambon, M Cibin, M Movalli, L Liberto, A Jaretti Sodano, F Girardi, Ines Giorgi, F Aliotta, M Forghieri, G Zucchi, Giovanni Corrao, E Majolino, F Biondini, D Mioni, A Marmora, P Vizzuso, I M Hinnenthal, Zambon, A, Airoldi, C, Corrao, G, Cibin, M, Agostini, D, Aliotta, F, Movalli, M, Biondini, F, Bizzi, P, Zucchi, G, Cerizza, G, Dattola, A, Marmora, A, Vittadini, G, Girardi, F, Liberto, L, Hinnenthal, I, Sodano, A, Vizzuso, P, Majolino, E, Mioni, D, Pedretti, L, Ranaletti, P, Forghieri, M, Spolaor, G, and Giorgi, I

Subjects
Adult, Male, medicine.medical_specialty, Pediatrics, Adolescent, Substance-Related Disorders, medicine.medical_treatment, 030508 substance abuse, Alcohol abuse, Logistic regression, Young Adult, 03 medical and health sciences, Patient Admission, 0302 clinical medicine, Prevalence, medicine, Humans, Prospective Studies, 030212 general & internal medicine, Psychiatry, MED/01 - STATISTICA MEDICA, Aged, Aged, 80 and over, Rehabilitation, business.industry, Mental Disorders, Alcohol dependence, General Medicine, Odds ratio, Middle Aged, Substance Abuse Treatment Center, Substance-Related Disorder, medicine.disease, Confidence interval, Alcoholism, Prospective Studie, Italy, Diagnosis, Dual (Psychiatry), Polysubstance dependence, Mental Disorder, Dual diagnosis, Female, Substance Abuse Treatment Centers, 0305 other medical science, business, Human
Abstract

Aims: Alcohol abuse has long been known as a disease with social and economic burden to society. Given the complex nature of alcohol treatment, it is worthwhile to examine the change over time of patients admitted to residential alcohol abuse rehabilitation units. Methods: The data were collected from two Italian projects on alcoholics performed in the mid- 1990s (ASSALT) and in 2009 (CORRAL), respectively. Categorical variables were considered in terms of absolute and relative frequencies. Comparisons of relative frequencies between groups were assessed by means of Fisher's exact test. Mixed logistic regression models were fitted to CORRAL data to identify the predictors of the probability of being a polysubstance abuser or having a dual diagnosis. The association estimates were reported as adjusted odds ratios and relative 95% confidence intervals. Results: Compared to the mid-1990s, in 2009 patients were older (P = 0.0003), with a higher level of education (P = 0.0204), with fewer comorbidities (liver disease except cirrhosis, P < 0.0001; polyneuropathy, P = 0.0001), more frequently polysubstance abusers (P < 0.0001), affected by dual diagnosis (P < 0.0001). In 2009, the probability of being a polysubstance abuser was higher in younger and in patients with dual psychiatric diagnosis. Female gender and polysubstance abuse were positively associated to the probability of being affected by dual psychiatric diagnosis. Conclusions: The increment of patients admitted to residential programs for alcohol dependence with polysubstance abuse and/or dual psychiatric diagnoses suggests the need to pay more attention to both psychological/psychiatric interventions and internal medicine/physical rehabilitation. Short summary: The results of this study suggest that further research is needed to identify the best treatment strategy that is safe and effective for the new population of alcoholics.

Published
2017

16. Neotropical xenarthrans: a data set of occurrence of xenarthran species in the Neotropics

Author

Guilherme Braga Ferreira, Javier de la Maza, Sandra M. C. Cavalcanti, Samir Gonçalves Rolim, Diana Letícia Kruger Pacheco Carvalho, Juan L. Peña-Mondragón, Jessica Castro-Prieto, Maria Luisa S. P. Jorge, Carlos De Angelo, Micheli Ribeiro Luiz, Daniel H. Thornton, Jesús A. Iglesias, Arthur Francisco Araújo Fernandes, Jonas Sponchiado, Juliani Bruna Zanoni, Lucas Lacerda Toth Quintilham, Thadeu Sobral-Souza, Daniel da Silva Ferraz, Rayana Diniz da Silva, Agustin Manuel Abba, María Eugenia Iezzi, Andreas Kindel, Flávia Regina Miranda, Gabriel Ivan Boaglio, Pamella Gusmão de Goés Brennand, Maurício Eduardo Graipel, Paula Alves Condé, Paulina Arroyo-Gerala, Rogério Cunha de Paula, Sebastián Andrés Costa, Natasha Moraes de Albuquerque, Teresa Cristina Anacleto, Erich Fischer, Adriano Garcia Chiarello, Fernando M. Contreras-Moreno, Roan McNab, André Luis Regolin, Zoila Vega Guarderas, Francesca Belem Lopes Palmeira, Rodrigo de Almeida Nobre, Marcia Maria de Assis Jardim, Diego Queirolo, Erika Castro, Luciano Carramaschi de Alagão Querido, Freddy Pérez-Garduza, Gabriel Favero Massocato, Karine Galisteo Diemer Lopes, Beatriz Fernandes Lima Luciano, Bruno Rodrigo de Albuquerque França, Enrique González, Giordano Ciocheti, Agustin Paviolo, Eleonore Z. F. Setz, Victor Gasperotto Krepschi, Felipe Martello, Juan Pablo Arrabal, Paulo de Tarso Zuquim Antas, Daiane Buscariol, Frederico Gemesio Lemos, Joana Zorzal Nodari, Cristiano Trapé Trinca, Fernanda Santos, Valéria da Cunha Tavares, Luis Renato Rezende Bernardo, Maria Angélica Barbosa Beccato, Juliana F. Ribeiro, Marina Ochoa Favarini, Alexine Keuroghlian, Cesar Rojano, Márcio Leite de Oliveira, Laura K. Honda, Lilian Elaine Rampim, Paloma Marques Santos, Nicolás Cantero, Helena Alves do Prado, Miriam Lucia Lages Perilli, Whaldener Endo, Diego Varela, Mauricio M. Núñez-Regueiro, Ernesto B.Viveiros de Castro, Fábio de Barros, Sebastián A. Ballari, Andreia Magro Moraes, Scarlat Dalva Ferreira, Lerrane de Fatima Cunha, William James Loughry, Ana Cecilia Ochoa, Alexandra Cravino Mol, Milton José de Paula, Igor Pfeifer Coelho, Samuel Eurich Betkowski, Erika de la Peña-Cuéllar, Milene Alves-Eigenheer, Evelyn Beatriz Brítez, Benoit de Thoisy, María Alicia de la Colina, Fabiana Lopes Rocha, Bibiana Gómez-Valencia, Cecília Licarião Luna, Hugo Fernandes-Ferreira, Gustavo Gonsioroski, Jeffrey J. Thompson, Deborah Faria, Izar Aximoff, Katyucha Von Kossel de Andrade Silva, Pierre-Cyril Renaud, Raone Beltrão-Mendes, Carlos Henrique Salvador, Alexandre Casagrande Faustino, Pedro Volkmer de Castilho, Paula Koeler Lira, Natalia Fraguas Versiani, Ricardo Sampaio, Santiago Carvalho, Marina Zanin, Geruza Leal Melo, Anne Karoline de Oliveira, Paulo Afonso Hartmann, Leonardo Carreira Trevelin, Marianela Velilla, Ana Raíssa Cunha Costa, Luiz Flamarion B. Oliveira, Patrício Adriano da Rocha, Carla Danielle de Melo-Soares, Dênis A. Sana, Danielle de Oliveira Moreira, Nivaldo Peroni, Carolina Depolito Melo, Marina Furlan Giubbina, José Julio de Toledo, Fredy Ramírez Pinto, Julio Chacón Pacheco, Javier Hinojosa, Pablo Gerardo Fernández Santiago, Maximiliano Augusto Benedetti, Vinícius Santana Orsini, Patrícia Gonçalves Guedes, Elisandra de Almeida Chiquito, Fabiane Girardi, Douglas de Matos Dias, Layla Reis de Andrade, Soledad de Bustos, Maria João Ramos Pereira, Wellington Hannibal, Mariana Bueno Landis, Juliano André Bogoni, Gindomar Gomes Santana, Eloisa Neves Mendonça, Miguel Coutinho Moretta Monteiro, Andre Monnerat Lanna, Isadora Beraldi Esperandio, Francys E. da Veiga da Costa, Sérgio Lucena Mendes, Wesley Dáttilo, Juan M. Campos Krauer, Sebastián Cirignoli, Fernando Gonçalves, Caryne Braga, Helena Godoy Bergallo, Ariane Teixeira Bertoldi, J. Antonio de la Torre, Luciana Souza Araújo, Paulo Marinho, Carla Cristina Gestich, Magnus Machado Severo, Ludmilla Oliveira Ribeiro, Juliane Pereira-Ribeiro, Jairo José Zocche, Mariana B. Nagy-Reis, Fernanda Zimmermann Teixeira, Fábio D. Mazim, Fernando Ferreira de Pinho, Leandro Perez Godoy, André Valle Nunes, Mozart C. Freitas-Junior, André Luiz Ferreira da Silva, Bruno Leles, Flávio Kulaif Ubaid, Fernando Pedroni, Vilmar Picinatto Filho, Sofia Marques Silva, Allison L. Devlin, Denise Lidoro de Mattia, William Douglas de Carvalho, Juan A. Martínez-Lanfranco, Marcela Alvares Oliveira, Bruna Silva Santos, Jorge Ferreira Lima Neto, Fernando Lima, Emiliano Guijosa-Guadarrama, Amadeo Sánchez, Juan I. Reppucci, Sixto Fernández Ramirez, Simonne Chinem, Ana Yoko Ykeuti Meiga, Vinicius A. G. Bastazini, Omar Correia Neto, Gabriel Lima Aguiar, Camila Cantagallo, Luiz H. Varzinczak, Italo Mourthe, Yamil Edgardo Di Blanco, Lydia Möcklinghoff, Bruna Gomes Oliveira, Stefani Gabrieli Age, Gabriel Preuss, Pryscilla Moura Lombardi, José Maurício Barbanti Duarte, Nicholas Gengler, Paul François Colas-Rosas, Paula Gonzalez Ciccia, Fernanda Guedes da Silva, Claudia Zukeran Kanda, Marcelo Hideki Yamane, Marina Lima da Silva, Gustavo Alvez da Costa Toledo, Cintia Gisele Tellaeche, Guilherme Cavicchioli, Larissa Oliveira Gonçalves, Juliana Silveira dos Santos, Alessandra Bertassoni, Newton Mota Filho, Nila Rássia Costa Gontijo, Maria Augusta Andrade da Silva, Guillermo E. Gil, Cyntia Cavalcante Santos, Alexandre Camargo Martensen, Anelise Montanarin, Barbara Zimbres, Anna Carolina Figueiredo de Albuquerque, Frédéric Delsuc, Mircea Mihart Hidalgo, Fernando R. Tortato, Breno Campelo Lima, Ana Cristina Mendes de Oliveira, Rodolfo Assis Magalhães, Eduardo Marques Santos, Ezequiel Pedó, Danianderson Rodrigues Carvalho, Marcelo Cervini, Antonio M. Mangione, Nereyda Falconi, Jose Roberto de Matos, Roberta Montanheiro Paolino, Mauricio Neves Godoi, Rodrigo Costa Araújo, Tayana Godim, Itiberê P. Bernardi, Daniel M. Casali, Alberto Gonzalez Gallina, Flávia P. Tirelli, Carlos Henrique de Freitas, Marcelo Juliano Rabelo Oliveira, Viviana B. Rojas Bonzi, Fernando A. Perini, Catalina Sánchez-Lalinde, Daniela Rodrigues Vasconcellos, Katia Maria Paschoaletto Micchi de Barros Ferraz, Juarez Carlos Brito Pezzuti, Julia Camara Assis, João Gabriel Ribeiro Giovanelli, Lucía Martínez Retta, Renata Twardowsky Ramalho Bonikowski, Rubem A.P. Dornas, Igor Kintopp Ribeiro, Alvaro García-Olaechea, Ricardo Sartorello, Camila Clozato Lara, Marcos Adriano Tortato, Clinton N. Jenkins, Anderson Feijó, Andrew J. Noss, Roque Lázaro de Gaspari Júnior, Alberto Yanosky, Gabriela Teixeira Duarte, Yaribeth Bravata de la Cruz, Erica Vanessa Maggiorini, Robson Odeli Espíndola Hack, Marcos de Souza Fialho, Noé U. de la Sancha, Camila Silveira Lima, Ricardo S. Bovendorp, Cláudia Bueno de Campos, Fernando Gaspari, Marcelo de Assumpção Pereira da Silva, Alexandre Reis Percequillo, Mauro Galetti, Manoel dos Santos-Filho, Filipe Pereira Rego Santos, Alexandre Martins Costa Lopes, Lucas Neves Perillo, Cindy M. Hurtado, Paula Akkawi, Lilian Bonjorne, Rony García Anleu, Julia Martinez Pardo, Anamélia de Souza Jesus, Ramon Lima Silva, Kena Ferrari Moreira da Silva, Franco L. Souza, Maria Santina de Castro Morini, Arnaud Leonard Jean Desbiez, Caroline Leuchtenberger, João Alves de Oliveira, Ailin Gatica, Luiza Neves Guimarães, Alan N. Costa, Gustavo Gabirele Gaspari, Colleen McDonough, Marcela Figuerêdo Duarte Moraes, Erick Francisco Aguiar, Átilla Colombo Ferreguetti, Denison José Henz, Adryelle Francisca de Souza Moreira, Eduardo G. Carrano, Cristina Jaques da Cunha, Edson Fiedler de Abreu-Júnior, Mariana Sampaio Xavier, Gabriel Selbach Hofmann, Ana Cristyna Reis Lacerda, Ricardo Corassa Arrais, Viviane Maria Guedes Layme, Paulo Ribeiro, Rodrigo Lima Massara, Francisco Grotta-Neto, Jéssica Caroline de Faria Falcão, Gustavo A. Marás, Milton Cezar Ribeiro, Elizandra de Matos Cardoso, Antonio Rossano Mendes Pontes, Armando Muniz Calouro, Tatiane Campos Trigo, Adriana Bocchiglieri, Bernardo Brandão Niebuhr, Otávio Santi Ribeiro, Wilson Roberto Spironello, Emiliano Esterci Ramalho, Ângela Camila Deffaci, Santiago Escobar, Rodrigo Raúl León Pérez, Akyllan Zoppi Medeiro, Ricardo Miranda Braga, Hugo Cabral, Maíra Benchimol, Sean Keuroghlian-Eaton, Juan Carlos Rudolf, Nina Attias, Felipe Moreli Fantacini, Jardel Brandão Seibert, Laura K. Marsh, Sérgio Bazilio, Laís dos Santos Everton, Fernando Cesar Cascelli de Azevedo, Marcelo Passamani, Liana Mara Mendes de Sena, Mario Henrique Alves, Franciane Almeida da Silva, Vinícius Peron de Oliveira Gasparotto, Karl-L. Schuchmann, Ana Carolina Srbek-Araujo, Emerson M. Vieira, Felipe Pedrosa, Clarissa Alves da Rosa, Ricardo Machado, Júlia Beduschi, Júlia Emi de Faria Oshima, Luiz Gustavo R. Oliveira-Santos, Henrique Villas Boas Concone, Alexandre Vogliotti, Leonardo Henrique da Silva, Débora Regina Yogui, Manuela Vieira dos Santos, Carlos Candia-Gallardo, Rafael Souza Cruz Alves, Marcelo Magioli, Adriano Pereira Paglia, Murillo Prado da Silva, Pablo Rodrigues Gonçalves, Marina Rivero, Jose Luis Cartes, Lívia de Almeida Rodrigues, Mayara Guimarães Beltrão, Felipe Bortolotto Peters, Jéssica Helena Mangueira Dias, Josué Santos Almeida, Robert L. Wallace, Ludmila Hufnagel, Daiane Cristina Carreira, Danielle D. Brown, Rogério Grassetto Teixeira da Cunha, Jorge José Cherem, Helio Secco, Pablo G. Perovic, Daniele Barcelos, Ubiratan Piovezan, Caetano Troncoso Oliveira, Elvira D'Bastiani, André Hirsch, Ana Maria de Oliveira Paschoal, Marina Xavier da Silva, Valeria Towns, Edgar Federico Rivadeneira, Marinêz Isaac Marques, Ronaldo Gonçalves Morato, Roxane Schaub, Marcus Vinícius Vieira, Ednaldo Cândido Rocha, Shirley Seixas Pereira Silva, Ingridi Camboim Franceschi, Rodrigo Ayala, Mariana Guenther, Fernando Carvalho, Paula Modenesi Ferreira, John Polisar, Rafael Reyna Hurtado, Burton K. Lim, Alejandro Jesus, Andressa Gatti, Agnis Cristiane de Souza, Pedro Henrique de Faria Peres, Luziene Conceição de Sousa, Gabriela S Oliveira, Alex Bager, Ana Kellen Nogueira Campelo, Marcell Soares Pinheiro, Carlos Eduardo Lustosa Esbérard, Marília A. S. Barros, Marcos Dums, Gabrielle Beca, Daniella Leal Ramos, Bruno Augusto Torres Parahyba Campos, Flavia Caruso, Marcelo Gordo, Diana Friedeberg, Fernanda Delborgo Abra, Luana Marina de Castro Mendonça, Carlos Benhur Kasper, Silvia Benito Santamaría, Fabio de Oliveira Roque, Cinthya Chiva dos Santos, Guilherme Mourão, José Fernando Moreira Ramírez, Rita de Cassia Bianchi, Mario S. Di Bitetti, Nacho Villar, Fernando C. Passos, Flávio Henrique Guimarães Rodrigues, Herbert Duarte, Sabrina Laurito, João Paulo Pandini Favoretti, Paula Cruz, Olivier Pays, Diego Astúa, Pedro Cordeiro Estrela, Saulo Ramos Lima, Cecília Bueno, Tadeu Gomes de Oliveira, Alessandro Rocha, Tainah Cruz Moreira, Laury Cullen, Lucas Lobo Barbosa, Carlos A. Peres, William Bercê, Sara Cortez, Raissa Danielle Praxedes Grangeiro, Rafael Hoogesteijn, Thiago Bernardes Maccarini, María José Andrade-Núñez, Carlos Eduardo Fragoso, Alex Augusto Abreu Bovo, Lucas Leuzinger, Nilton C. Cáceres, Luiz Henrique Medeiros Borges, Joceleia G. Koenemann, Nielson Pasqualotto, Rugieri Juárez, Graziele Oliveira Batista, Micaela Camino, Kathrin Burs, Andrezza Bellotto Nobre, Elildo A.R. Carvalho, Nathália Fernandes Canassa, Donald P. Eaton, Carlos Rodrigo Brocardo, Bráulio A. Santos, Fernanda Cavalcanti de Azevedo, Nicole da Rosa Oliveira, Thiago Ferreira Rodrigues, Verónica Andrea Quiroga, Bernardo Papi, André Luis Moura Botelho, Hugo Fernando del Castillo Cordero, Rosane Vieira Marques, Hugo Reis Medeiros, Gastón Andrés Fernandez Giné, Natalia Mariana Denkiewicz, Vinicius Rodrigues Tonetti, Rafael de Souza Laurindo, Paula Fabiana Pinheiro, Larissa L. Bailey, Martin Roberto Del Valle Alvarez, Ezequiel Vanderhoeven, Vinicius Alberici, Cynthia Elisa Widmer, Claudia Regina Silva, Leonardo Sartorello, Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UR226, Marcos Santos P., Bocchiglieri A., Garcia Chiarello A., Pereira Paglia A., Moreira A., Souza A.C., Abba A.M., Gatica A., Zoppi Medeiro A., Costa A.N., Gonzalez Gallina A., Yanosky A., Jesus A., Bertassoni A., Rocha A., Abreu Bovo A.A., Bager A., Cravino Mol Alexandra, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Ecología y Ciencias Ambientales., Camargo Martensen A., Casagrande Faustino A., Martins Costa Lopes A., Reis Percequillo A., Vogliotti A., Keuroghlian A., Colina M.A., Devlin A., García-Olaechea A., Sánchez A., Srbek-Araujo A.C., Ochoa A.C., Mendes Oliveira A.C., Reis Lacerda A.C., Nogueira Campelo A.N., Oliveira Paschoal A.M., Cunha Costa A.R., Ykeuti Meiga A.Y., Souza Jesus A., Feijó A., Hirsch A., Ferreira da Silva A.F., Moura Botelho A.L., Regolin A.L., Monnerat Lanna A., Valle Nunes A., Kindel A., Magro Moraes A., Gatti A., Noss A., Bellotto Nobre A., Montanarin A., Deffaci A.C., Figueiredo de Albuquerque A.C., Oliveira A.K., Mangione A.M., Rossano Mendes Pontes A., Teixeira Bertoldi A., Muniz Calouro A., Desbiez A., Fernandes A., Colombo Ferreguetti A., Andrade da Silva M.A., Zimbres B., Fernandes Lima Luciano B., Thoisy B., Niebuhr B.B., Papi B., Gómez-Valencia B., Santos B., Campelo Lima B., Gomes Oliveira B., Silva Santos B., Torres Parahyba Campos B.A., Leles B., Albuquerque França B.R., Lim B., Troncoso Oliveira C., Cantagallo C., Clozato Lara C., Silveira Lima C., Gestich C.C., Melo-Soares C.D., Peres C., Benhur Kasper C., Candia-Gallardo C., Angelo C., Fragoso C.E., Freitas C.H., Salvador C.H., Brocardo C.R., Depolito Melo C., Leuchtenberger C., Braga C., Sánchez-Lalinde C., Bueno C., Licarião Luna C., Rojano C., Hurtado C.M., Santos C.C., Tellaeche C., Rosa C., Bueno de Campos C., Silva C.R., Zukeran Kanda C., Jenkins N., McDonough C., Trapé Trinca C., Jaques da Cunha C., Widmer C.E., Santos C., Buscariol D., Carreira D.C., Rodrigues Carvalho D., Silva Ferraz D., Casali D., Thornton D., Rodrigues Vasconcellos D., Barcelos D., Brown D., Leal Ramos D., Oliveira Moreira D., Yogui D.R., Faria D., Sana D.A., Lidoro de Mattia D., Henz D.J., Friedeberg D., Kruger Pacheco Carvalho D.L., Astúa D., Queirolo D., Varela D., Eaton D., Matos Dias D., Rivadeneira E.F., Rocha E.C., Abreu-Júnior E.F., Carrano E., Marques Santos E., Freire Setz E.Z., Alves Ribeiro Carvalho E., Almeida Chiquito E., Matos Cardoso E., Neves Mendonça E., D’Bastiani E., Vieira E., Ramalho E.E., Guijosa-Guadarrama E., González E., Maggiorini E.V., Fischer E., Aguiar E.F., Castro E.P., Peña-Cuéllar E., Viveiros de Castro E., Brítez E.B., Vanderhoeven E.A., Pedó E., Lopes Rocha F., Girardi F., Oliveira Roque F., Dias Mazim F., Monteiro de Barros F., Martello F., Moreli Fantacini F., Pedrosa F., Bortolotto Peters F., Delborgo Abra F., Cavalcanti de Azevedo F., Silva Santos F., Guedes da Silva F., Zimmermann Teixeira F., Araujo Perini F., Passos F., Carvalho F., Cascelli de Azevedo F.C., Ferreira de Pinho F., Gonçalves, Lima F., Contreras-Moreno F., Pedroni F., Tortato F.R., Pereira Rego Santos F., Caruso F., Pereira Tirelli F., Miranda F.R., Guimarães Rodrigues F.H., Kulaif Ubaid F., Lopes Palmeira F.B., Almeida da Silva F., Grotta-Neto F., Souza F.L., Costa F.E., Pérez-Garduza F., Delsuc F., Lemos F.G., Ramirez Pinto F., Boaglio G.I., Fávero Massocato G., Preuss G., Selbach Hofmann G., Lima Aguiar G., Schuck Oliveira G., Teixeira Duarte G., Beca G., Fernandez Giné G.A., Oliveira Batista G., Gil G.E., Gonsioroski G., Secco H., Reis Medeiros H., Pfeifer Coelho I., Camboim Franceschi I., Bernardi I., Torre J.A., Zocche J.J., Seibert J.B., Faria Falcão J.C., Mangueira Dias J.H., Zorzal Nodari J., Alves Oliveira J., Ribeiro Giovanelli J.G., Pandini Favoretti J.P., Polisar J., Sponchiado J., Cherem J.J., Moreira Ramírez J.F., Toledo J.J., Barbanti Duarte J.M., Matos J.R., Arrabal J.R., Faria Oshima J.E., Fernandes Ribeiro J., Bogoni J.A., Chacón Pacheco J.A., Schuchmann K., Ferraz K., Santos Everton L., Bailey L., Oliveira Gonçalves L., Cullen L., Reis de Andrade L., Carreira Trevelin L., Bonjorne L., Almeida Rodrigues L., Leuzinger L., Neves Perillo L., Souza Araújo L., Hufnagel L., Oliveira Ribeiro L., Rezende Bernardo L.R., Rodrigues Oliveira-Santos L.G., Varzinczak L.H., Medeiros Borges L.H., Neves Guimarães L.H., Möcklinghoff L., Alvares Oliveira M., Magioli M., Assis Jardim M.M., Leite de Oliveira M., Tortato M.A., Dums M., Iezzi M.E., Ramos Pereira M.J., Jorge M.J., Castro Morini M.S., Bueno Landis M., Sampaio Xavier M., Barros M., Lima da Silva M., Rivero M., Zanin M., Marques I.M., Alves M.H., Di Bitetti M., Alvarez M., Graipel M.E., Neves Godoi M., Benedetti M.A., Guimarães Beltrão M., Coutinho Moretta Monteiro M., Paula M.J., Lages Perilli M.L., Prado da Silva M., Villar N., Moraes De Albuquerque N., Canassa N., Mota Filho N., Rosa Oliveira N., Pasqualotto N., Cáceres N.C., Attias N., Ochoa Favarini M., Santi Ribeiro O., Rodrigues Gonçalves P., Rocha P.A., Alves Condé P., Akkawi P., Koeler Lira P., Cruz P., Modenesi Ferreira P., Arroyo-Gerala P., Hartmann P.A., Tarso Zuquim Antas P., Marinho P.H., Faria Peres P.H., Peña-Mondragón J.L., Moura Lombardi P., Souza Laurindo R., Souza Cruz Alves R., Praxedes Grangeiro R.D., Lima Silva R., Beltrão-Mendes R., Twardowsky Ramalho Bonikowski R., Reppucci J., Corassa Arrais R., Sampaio R., Sartorello R., Siqueira Bovendorp R., McNab R., Espíndola Hack R.O., Assis Magalhães R., Costa Araújo R., Almeida Nobre R., León Pérez R.R., Lima Massara R., Cunha de Paula R., García Anleu R., Vieira Marques R., Dornas R., Gonçalves Rolim S., Cavalcanti S., Ramos Lima S., Ballari S., Santamaría S.B., Marques Silva S., Age S.G., Godim T., Sobral-Souza T., Bernardes Maccarini T., Ferreira Rodrigues T., Piovezan U., Cunha Tavares V., Quiroga V.A., Gasperotto Krepschi V., Picinatto Filho V., Galvão Bastazini V.A., Oliveira Gasparotto V.P., Santana Orsini V., Guedes Layme V.M., Hannibal W., Dáttilo W., Carvalho W.D., Loughry W.J., Di Blanco Y.E., Núñez-Regueiro M., Furlan Giubbina M., Passamani M., Carramaschi de Alagão Querido L., Alvez da Costa Toledo G., Kintopp Ribeiro I., Quintilham L., Bustos S., Maza J., Ferreira Lima Neto J., Von Kossel de Andrade Silva K., Sartorello L., Rampim L.E., Marás G., Camino M., Freitas-Junior M.C., Perovic P.G., Montanheiro Paolino R., Ferreira S.D., Towns V., Beraldi Esperandio I., Aximoff A., Beduschi J., Guenther M., Cassia Bianchi R., Keuroghlian-Eaton K., Lucena Mendes S., Fatima Cunha L., Cirignoli S., Ciocheti G., Alves do Prado H., Fernandes-Ferreira F., Mendes de Sena L.M., Hideki Yamane M., Brennand P., Silva R.D., Escobar S., Endo W., Reyna Hurtado R., Costa Gontijo R., Marsh L., Machado Severo M., Martinez Pardo J., Costa S.A., Leal Melo G., Gomes Santana G., Miranda Mourão G., Gaspari G.G., Duarte H., Cabral H., Silva L.H., Mendonça L., Barbosa L.L., Vieira dos Santos M., Figuerêdo Duarte Moraes M., Gordo M., Fraguas Versiani N., Cantero N., Pays O., Gonçalves Guedes P., Colas-Rosas P.F., Ribeiro P., Renaud P.C., Hoogesteijn R.J., Ayala R., Grassetto Teixeira da Cunha R., Schaub R., Laurito S., Eurich Betkowski S., Cortez S., Pereira Silva S.S., Gomes de Oliveira T., Spironello W.R., Gengler N., Mihart Hidalgo M., Juárez R., Iglesias J., Anacleto T.C., Souza Fialho M., Cavicchioli G., Barbosa Beccato M.A., Silva M., Correia Neto O., Galisteo Diemer Lopes K., Perez Godoy L., Ribeiro Luiz M., Rojas Bonzi V., Braga Ferreira G., Rabelo Oliveira M.J., Hinojosa J., Barbosa de Oliveira L.F., Nagy-Reis M.B., Fernández Ramirez S., Villas Boas Concone H., Mourthe I., Martínez-Lanfranco J., Zanoni J.B., Cruz Moreira T., Vega Guarderas Z., Bazilio S., Cervini M., Soares Pinheiro M., Gonçalves Morato R., Peroni N., Campos Trigo T., Bomfim Machado R., Gaspari F., Koenemann J., Rudolf J.C., Benchimol M., Vieira M.V., Martínez Retta L., Fernández Santiago P.G., Gonzalez Ciccia P., Cordeiro Estrela P., Carvalho S., Lustosa Esbérard C.E., Bravata-de la Cruz Y., Castro-Prieto J., Miranda Braga R., Cartes J.L., Andrade-Núñez M.J., Denkiewicz N.M., Falconi N., Brito Pezzuti J.C., Castillo Cordero H.E., Conceição de Sousa L., Gaspari Júnior R.L., Santos-Filho M., Almeida J.S., Thompson J., Silveira dos Santos J., Pereira-Ribeiro J., Burs K., Ferrari Moreira da Silva K., Velilla M., Xavier da Silva M., Sancha N., Pinheiro P.F., Volkmer de Castilho P., Bercê W., Camara Assis J., Rodrigues Tonetti V., Alves-Eigenhee M., Chinem S., Honda L., Godoy Bergallo H., Alberici V., Wallace R., Campos Krauer J.M., Ribeiro M.C., and Galetti M.

Subjects
0106 biological sciences, NEOTROPICAL REGION, biodiversity hotspot, xenarthra, habitat loss, Pilosa, HABITAT LOSS, Forest fragmentation, XENARTHRA, 010603 evolutionary biology, 01 natural sciences, purl.org/becyt/ford/1 [https], PILOSA, Ciencias Biológicas, Cingulata, neotropical mammals, purl.org/becyt/ford/1.6 [https], NEOTROPICAL MAMMALS, ComputingMilieux_MISCELLANEOUS, Ecology, Evolution, Behavior and Systematics, forest fragmentation, BIODIVERSITY HOTSPOT, pilosa, biology, Ecology, 010604 marine biology & hydrobiology, Xenarthra, FOREST FRAGMENTATION, Ecología, biology.organism_classification, Biodiversity hotspot, Data set, Geography, Habitat destruction, cingulata, neotropical region, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, CINGULATA, CIENCIAS NATURALES Y EXACTAS
Abstract

Xenarthrans -anteaters, sloths, and armadillos- have essential functions for ecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosystem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts with domestic dogs, these species have been threatened locally, regionally, or even across their full distribution ranges. The Neotropics harbor 21 species of armadillos, 10 anteaters, and 6 sloths. Our data set includes the families Chlamyphoridae (13), Dasypodidae (7), Myrmecophagidae (3), Bradypodidae (4), and Megalonychidae (2). We have no occurrence data on Dasypus pilosus (Dasypodidae). Regarding Cyclopedidae, until recently, only one species was recognized, but new genetic studies have revealed that the group is represented by seven species. In this data paper, we compiled a total of 42,528 records of 31 species, represented by occurrence and quantitative data, totaling 24,847 unique georeferenced records. The geographic range is from the southern United States, Mexico, and Caribbean countries at the northern portion of the Neotropics, to the austral distribution in Argentina, Paraguay, Chile, and Uruguay. Regarding anteaters, Myrmecophaga tridactyla has the most records (n = 5,941), and Cyclopes sp. Have the fewest (n = 240). The armadillo species with the most data is Dasypus novemcinctus (n = 11,588), and the fewest data are recorded for Calyptophractus retusus (n = 33). With regard to sloth species, Bradypus variegatus has the most records (n = 962), and Bradypus pygmaeus has the fewest (n = 12). Our main objective with Neotropical Xenarthrans is to make occurrence and quantitative data available to facilitate more ecological research, particularly if we integrate the xenarthran data with other data sets of Neotropical Series that will become. Fil: Marques Santos, Paloma. Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas; Brasil Fil: Bocchiglieri, Adriana. Universidade Federal de Sergipe; Brasil Fil: Garcia Chiarello, Adriano. Universidade de Sao Paulo; Brasil Fil: Pereira Paglia, Adriano. Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas; Brasil Fil: Moreira, Adryelle. Amplo Engenharia e Gestão de Projetos ; Brasil Fil: Abba, Agustin Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; Argentina Fil: Paviolo, Agustin Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Universidad Nacional de Misiones. Instituto de Biología Subtropical; Argentina Fil: Gatica, Ailin. Universidad Nacional de San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina Fil: Ochoa, Ana Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina Fil: de Angelo, Carlos Daniel. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente.; Argentina Fil: Tellaeche, Cintia Gisele. Universidad Nacional de Jujuy. Facultad de Ciencias Agrarias. Centro de Estudios Ambientales Territoriales y Sociales; Argentina. Universidad Nacional de Jujuy. Instituto de Ecorregiones Andinas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Ecorregiones Andinas; Argentina Fil: Varela, Diego Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú; Argentina Fil: Vanderhoeven, Ezequiel Andres. Ministerio de Salud. Instituto Nacional de Medicina Tropical; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Caruso, María Flavia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Administración de Parques Nacionales. Delegación Regional del Noroeste; Argentina Fil: Arrabal, Juan Pablo. Secretaria de Gobierno de Salud. Instituto Nacional de Medicina Tropical - Sede Puerto Iguazú Misiones; Argentina. Centro de Investigaciones del Bosque Atlántico; Argentina Fil: Iezzi, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú; Argentina Fil: Di Bitetti, Mario Santiago. Centro de Investigaciones del Bosque Atlántico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú; Argentina Fil: Cruz, Paula Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú; Argentina. Centro de Investigaciones del Bosque Atlántico; Argentina Fil: Reppucci, Juan Ignacio. Administración de Parques Nacionales. Delegación Regional del Noroeste; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Benito Santamaria, Silvia. Centro de Investigaciones del Bosque Atlántico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú; Argentina Fil: Quiroga, Verónica Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Diversidad y Ecología Animal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Diversidad y Ecología Animal; Argentina Fil: Di Blanco, Yamil Edgardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú; Argentina Fil: Marás, Gustavo Arnaldo. Administración de Parques Nacionales. Delegación Regional del Noroeste; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Camino, Micaela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Centro de Ecología Aplicada del Litoral. Universidad Nacional del Nordeste. Centro de Ecología Aplicada del Litoral; Argentina Fil: Perovic, Pablo Gastón. Administración de Parques Nacionales. Delegación Regional del Noroeste; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Martínez Pardo, Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú; Argentina Fil: Costa, Sebastián Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Puerto Iguazú; Argentina Fil: Pinheiro, Fabiana. Universidade Federal do Rio Grande do Sul; Brasil Fil: Volkmer de Castilho, Pedro. Universidade Federal de Santa Catarina; Brasil Fil: Bercê, William. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil Fil: Camara Assis, Julia. Universidade Estadual Paulista Julio de Mesquita Filho. Faculdade de Engenharia.; Brasil Fil: Rodrigues Tonetti, Vinicius. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil Fil: Alves Eigenheer, Milene. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil Fil: Chinem, Simonne. Universidade de Sao Paulo; Brasil Fil: Honda, Laura K.. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil Fil: Bergallo, Helena de Godoy. Universidade do Estado de Rio do Janeiro; Brasil Fil: Alberici, Vinicius. Universidade de Sao Paulo; Brasil Fil: Wallace, Robert. Wildlife Conservation Society; Estados Unidos Fil: Ribeiro, Milton Cezar. Universidade de Sao Paulo; Brasil Fil: Galetti, Mauro. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil

Published
2019

17. A Study on Texture and Acoustic Properties of Cold Laid Microsurfacings

Author

Cesare Sangiorgi, Fabrizio Girardi, Claudio Lantieri, Gabriele Bitelli, Federico Irali, Sangiorgi C., Bitelli G., Lantieri C., Irali F., and Girardi F.

Subjects
Petroleum engineering, Waste management, Acoustic properties, RUBBER ASPHALT, Thin layer, MICROSURFACINGS, Bituminous microsurfacing, Surface finish, COLD SLURRY, ACOUSTIC SURFACE, Cracking, Skid (automobile), Slurry, Species evenness, Environmental science, General Materials Science, Crumb rubber, Texture, 3D Laser scanner, 3d laser scanner
Abstract

Slurry microsurfacing is an economical maintenance intervention that provides effective skid resistance and surface evenness in a thin layer, thus improving the road safety. Researchers aimed to develop an innovative application of slurry seal, capable of gathering in a single material some technical solutions for various functional and environmental aspects. The purposes of this intervention are: restoring skid resistance, sealing surface cracking, reducing tire/pavement noise, adding crumb rubber from tires as a recycling material and reducing atmospheric emissions using the cold technique. A 3D laser scanner device has been used to evaluate the surface texture and analyze the roughness parameters.

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results