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Triplet supercurrents in multilayer ferromagnetic Josephson junctions with misaligned magnetization can penetrate thicker ferromagnetic barriers compared to the singlet component. Although the static properties of these junctions have been extensively studied, the dynamic characteristics remain largely unexplored. Here we report a comprehensive electrodynamic characterization of multilayer ferromagnetic Josephson junctions composed of Co and Ho. By measuring the temperature-dependent current-voltage characteristics and the switching current distributions down to 0.3 K, we show that phase dynamics of junctions with triplet supercurrents exhibits long (in terms of proximity) junction behavior and moderately damped dynamics with renormalized capacitance and resistance. This unconventional behavior possibly provides a different way to dynamically detect triplets. Our results show new theoretical models are required to fully understand the phase dynamics of triplet Josephson junctions for applications in superconducting spintronics., DM, RC, FT would like to thank NANOCOHYBRI project (Cost Action CA 16218). NB acknowledges funding from the British Council through UKIERI programme and Loughborough University. MGB acknowledges funding from EPSRC Programme Grant EP/N017242/1.

High critical temperature superconductors (HTS) based devices can have impact in the study of the phase dynamics of Josephson junctions (JJs) thanks to the wide range of junction parameters they offer and to their unconventional properties. Measurements of current-voltage characteristics and of switching current distributions constitute a direct way to classify different regimes of the phase dynamics and of the transport, also in nontrivial case of the moderately damped regime (MDR). MDR is going to be more and more common in JJs with advances in nanopatterning superconductors and synthesizing novel hybrid systems. Distinctive signatures of macroscopic quantum tunneling and of thermal activation in presence of different tunable levels of dissipation have been detected in YBCO grain boundary JJs. Experimental data are supported by Monte Carlo simulations of the phase dynamics, in a wide range of temperatures and dissipation levels. This allows us to quantify dissipation in the MDR and partially reconstruct a phase diagram as guideline for a wide range of moderately damped systems. (C) 2014 Elsevier B.V. All rights reserved.

Recent findings by G.Pepe et al. (Appl.Phys.Lett.89, 2770, 2001) have given new insights over the dynamics of Josephson junctions subject to electronic pulse injection. These experiments can be considered important steps toward the study of non-equilibrium effects involved in junctions under very fast (e.g. laser induced) pumping signals. In the governing equations (sine-Gordon or coupled sine-Gordon depending on the system) pulse operation enters via Josephson current distribution or via bias current distribution. By means of numerical simulations here we study the dependence of the switching to resistive state on fast local depression of Josephson current. Next, using simulated electronic pulse train we show how the flip-flop operating mode found in G.Pepe et al. is a common feature of single or stacked Josephson systems without regard for the pulse waveform or the presence of the gap structure in the I-V characteristics. The effect of the length and of the magnetic field is also discussed.

Galanin released into the hypophysial portal circulation in the hypothalamus may function as a hypophysiotropic factor regulating the anterior pituitary function or it may function as a neurotransmitter/neuromodulator acting at synaptic sites regulating neuronal activity of many neurons in the brain. Catecholamines (adrenaline, noradrenaline, and dopamine) primarily regulate anterior pituitary functions indirectly via innervating hypophysiotropic neurons. The aim of the present studies was to explore with double-label immunocytochemistry if, as in rodents, catecholamines interact with galanin in the human diencephalon. Due to the long post-mortem period and subsequent lack of optimal preservation of the cell membranes in the brain, electron microscopy could not be employed to show the presence of catecholaminergic-immunoreactive synapses on galanin-immunoreactive neurons. Therefore, we used light microscopic immunocytochemistry and high-magnification microscopy with oil immersion to identify putative juxtapositions between catecholamines and galanin-utilizing antisera against key enzymes of catecholamine synthesis (tyrosine hydroxylase (TH), representing all three catecholamines; dopamine-beta-hydroxylase (DBH), representing noradrenaline; and phenylethanolamine-N-methyltransferase (PNMT), representing adrenaline) and galanin. Our studies show that among the three catecholamines, dopamine is the most abundant and the vast majority of catecholaminergic contacts on galanin-immunoreactive neurons is dopaminergic. The number of DBH-immunoreactive contacts is less and the number of PNMT-immunopositive contacts is negligible. Among the hypothalamic regions, the periventricular region above the infundibulum (infundibular or arcuate nucleus) contained the largest number of contacts. These en passant-type intimate associations between catecholamine- and galanin-immunoreactive neuronal elements may be functional synapses and may provide the morphological basis for the catecholamine-mediated galanin release.

The behavior of a Josephson system under pulsed operation is of utmost importance for developing reliable digital devices working at very high clock frequencies. Information about effect of thermal noise over pulsed operation is also useful to design errors free devices. Recent experiments in a system of two stacked junctions show that pulses applied to the first junction (injector) of the stack drive the Josephson biased second junction (detector) in the resistive state. The experiment was interpreted as pulsed-assisted escape toward resistive state as a consequence of an excitation of large non-linear oscillations in the detector junction that, with the contribution of thermal noise, drives out the junction from the zero voltage state. Moreover, an unstability of the resistive state toward the zero voltage state under the same pulsed operation was also noted. By means of a systematic numerical approach to the problem, we present a study of the pulsed-assisted escape using the framework of the thermal escape theory for the direct transition from zero voltage state to resistive state. We study the single junction case and a stacked configuration as examples of different systems showing pulsed-assisted escape. (C) 2002 Elsevier Science B.V. All rights reserved.

Stress is considered to be a major factor in the regulation of growth. Psychosocial dwarfism, characterized with short stature, delayed puberty, and depression, is typically preceded by psychological harassment or stressful environment. It has been observed that stress suppresses GH secretion, possibly via the attenuation of GHRH secretion. However, the exact mechanism of the impact of stress on growth has not been elucidated yet.Our previous studies revealed intimate associations between neuropeptide Y (NPY)-immunoreactive (IR) axonal varicosities and GHRH-IR perikarya in the human hypothalamus. Because NPY is considered to be a stress molecule, NPY-GHRH juxtapositions may represent an important factor of stress-suppressed GHRH release. In addition to NPY, catecholamines are among the major markers of stress. Thus, in the present study, we examined the putative juxtapositions between the catecholaminergic tyrosine hydroxylase (TH)-/dopamine-β-hydroxylase-/phenylethanolamine N-methyltransferase-IR and GHRH-IR neural elements in the human hypothalamus. To reveal these juxtapositions, double-label immunohistochemistry was used.Our findings revealed that the majority of the GHRH-IR perikarya formed intimate associations with TH-IR fiber varicosities. The majority of these juxtapositions were found in the infundibular nucleus/median eminence.The lack of phenylethanolamine N-methyltransferase-GHRH associations and the small number of dopamine-β-hydroxylase-GHRH juxtapositions suggest that the vast majority of the observed TH-GHRH juxtapositions represent dopaminergic associations. The density of the abutting TH-IR fibers on the surface of the GHRH perikarya suggests that these juxtapositions may be functional synapses, and thus, in addition to NPY, catecholamines may regulate GHRH secretion via direct synaptic mechanisms.

Neuropeptide Y (NPY) is a 36 amino acid peptide, which among others, plays a pivotal role in stress response. Although previous studies confirmed that NPY release is increased by stress in several species, the exact mechanism of the stress-induced NPY release has not been elucidated yet. In the present study, we examined, with morphological means, the possibility that catecholamines directly influence NPY release in the human hypothalamus. Since the use of electron microscopic techniques is virtually impossible in immunostained human samples due to the long post mortem time, double-label immunohistochemistry was utilised in order to reveal the putative catecholaminergic-NPY associations. The present study is the first to demonstrate juxtapositions between the catecholaminergic, tyrosine hydroxylase (TH)/dopamine-beta hydroxylase (DBH)-immunoreactive (IR) and NPY-IR neural elements in the human hypothalamus. These en passant type associations are most numerous in the infundibular and periventricular areas of the human diencephalon. Here, NPY-IR neurons often form several contacts with catecholaminergic fibre varicosities, without any observable gaps between the contacting elements, suggesting that these juxtapositions may represent functional synapses. The lack of phenylethanolamine N-methyltransferase (PNMT)-NPY juxtapositions and the relatively few observed DBH-NPY associations suggest that the vast majority of the observed TH-NPY juxtapositions represent dopaminergic synapses. Since catecholamines are known to be the crucial components of the stress response, the presence of direct, catecholaminergic (primarily dopaminergic)-NPY-IR synapses may explain the increased NPY release during stress. The released NPY in turn is believed to play an active role in the responses that are directed to maintain the homeostasis during stressful conditions.

Previous studies have demonstrated that catecholaminergic, tyrosine hydroxylase (TH)-immunoreactive (IR) perikarya and fibers are widely distributed in the human hypothalamus. Since TH is the key and rate-limiting enzyme for catecholaminergic synthesis, these IR neurons may represent dopaminergic, noradrenergic or adrenergic neural elements. However, the distribution and morphology of these neurotransmitter systems in the human hypothalamus is not entirely known. Since the different catecholaminergic systems can be detected by identifying the neurons containing the specific key enzymes of catecholaminergic synthesis, in the present study we mapped the catecholaminergic elements in the human hypothalamus using immunohistochemistry against the catecholaminergic enzymes, TH, dopamine beta-hydroxylase (DBH) and phenylethanolamine-N-methyltransferase (PNMT). Only a few, PNMT-IR, adrenergic neuronal elements were found mainly in the infundibulum and the periventricular zone. DBH-IR structures were more widely distributed in the human hypothalamus occupying chiefly the infundibulum/infundibular nucleus, periventricular area, supraoptic and paraventricular nuclei. Dopaminergic elements were detected by utilizing double label immunohistochemistry. First, the DBH-IR elements were visualized; then the TH-IR structures, that lack DBH, were detected with a different chromogen. In our study, we conclude that all of the catecholaminergic perikarya and the majority of the catecholaminergic fibers represent dopaminergic neurons in the human hypothalamus. Due to the extremely small number of PNMT-IR, adrenergic structures in the human hypothalamus, the DBH-IR fibers represent almost exclusively noradrenergic neuronal processes. These findings suggest that the juxtapositions between the TH-IR and numerous peptidergic systems revealed by previous reports indicate mostly dopaminergic synapses.

We have observed energy level quantization in an all high critical temperature superconductor d-wave Josephson junction. From the measurements we have also extracted the quality factor Q of the junction which is of the order of 40. These results indicate that the role of dissipation mechanisms in high temperature superconductors has to be revised, and may also have consequences for the class of solid state “quiet” quantum bit with longer coherence time.

We have measured the energy level separation from the ground state to the first excited state in a high critical temperature superconductor d-wave Josephson junction. We observe that the bias current dependence of the energy level separation is strongly affected by the large shunt capacitance and inductance of the junction electrodes. In order to describe the effect of a shunt capacitance and shunt inductance on the junction dynamics we derive the equation of motion of the total system. In general such a circuit displays two resonance frequencies corresponding to two different energy scales. We discuss various limits for the values of the shunt inductor and capacitor.

We report on the latest developments in the study of transport properties of YBa2Cu3O7-delta (YBCO)-based grain boundary (GB) biepitaxial Josephson junctions. We have successfully extended the fabrication process, originally developed for (110) oriented SrTiO3 substrates, to (110) oriented LaAlO3 substrates in view of microwave applications. We will report, also, on the observation of conductance fluctuations, we believe related to the coherent diffusion of quasi-particles across the GB. These results, together with the recent observation of macroscopic quantum tunneling and energy level quantization in these junctions, could help cast some light on the mechanism involved in transport across grain boundaries and in revising the role and the effect of quasi particles in d-wave transport.

The predominant d-wave pairing symmetry in high temperature superconductors leads to an unconventional current - phase relation in Josephson junctions. This circumstance may induce new effects in the dynamics of dc SQUIDs. In this contribution we report on the measurements of the dependence of the SQUID Josephson current on the external magnetic field taken at very low temperatures, down to 20 mK. Different grain boundaries have been fabricated by using the biepitaxial and the bicrystal technique. Some of the effects which are induced by a nonsinusoidal current - phase relation can be clearly identified in the dynamics of the SQUIDs. The experimental data are also compared with theoretical simulations taking into account the inductance of the loop. The data show that, in specific conditions, a non-negligible inductance of the loop can induce effects similar to an unconventional current - phase relation, with a pronounced second harmonic sin( 2 phi) term. This fact has to be taken into account when designing d- wave SQUIDs for quantum circuitry.

We describe the main ideas and some experimental outcomes of two experiments, both aimed to study quantum tunneling effects in high-T-C structures. In the first experiment, macroscopic quantum tunneling is demonstrated in grain boundary YBaCuO Josephson junctions revealing dissipation levels lower than expected and opening novel perspectives for quantum circuitry. In the second, the low temperature dissipation is dominated by quantum tunneling of individual Pearl vortices in ultra-thin CaBaCuO systems characterized by extremely long Pearl lengths. (c) 2006 Elsevier B.V. All rights reserved.

One of the stimulating area of superconductors investigations lies in the achieved and potential applications as radiation detectors. Results concerning annular Josephson junctions in this context are discussed. Fundamental aspects, mainly related to the fluxon dynamics in such structures, are discussed in detail. The results confirm the importance of the precious sharing of technological requests with fundamental physical implications. Peculiar results are reported dealing with new resonances occurring on these Josephson junctions of annular configuration.

The presence of spontaneous currents in unconventional Josephson junctions gives rise to the possibility of using zero magnetic field magnetization states in an unconventional loop as qubit states in a Josephson quantum computing device. However, the advantage of zero field may be insufficient to overcome the problems arising in the design and fabrication of low-noise, low-dissipation, reproducible devices. On the other hand, low-T/sub c/ "flux" devices suffer the same problems though their perspectives are more promising. The solution could be an increase in the device complexity, but with the gain of an effective advantage on the external noise rejection of the system during quantum evolution. Using advanced fabrication techniques it is now possible to build Josephson junction arrays made of superconducting unconventional loops. On this basis, a new qubit device can be designed as a ring array of unconventional loops. From a theoretical point of view this device is analogous to an annular Josephson junction, but with a "built in" natural degeneracy. For their topological and energetical properties, such arrays could be excellent devices for the qubit circuitry usable as the basic building blocks for quantum computing devices. In this work, we show how some of the principles of qubit design could be implemented in such devices.

The magnetic behaviour of multiply connected superconductors (MCS) can be described by analysing the simplest loop structures containing Josephson junctions: conventional loops with all conventional Josephson junctions and π-loops with an odd subset of π-junctions. The latter are unconventional Josephson junctions in which the coupling has the reversed sign and appears in the ceramic materials as a consequence of d-pairing. Among MCS, the magnetic behaviour of large β two-dimensional Josephson junction arrays (JJA) is based on the single loop behaviour. Solving full mutual inductance Josephson junction square array equations with and without π-loops shows that the mutual inductance coupling influences the distribution of π/conventional loops without substantially altering their single loop magnetization. The JJA mean magnetic behaviour in a low field can be recovered using a simple energy approach based on the single loop solutions avoiding the solution of the array equations. Also, we draw some consequences on the behaviour of more complex MCS as high-Tc ceramics and their observed paramagnetic susceptibilities (paramagnetic Meissner effect).

LTC Josephson junction arrays (JJA) have recently gained interest as a model for the study of magnetization in superconductor materials. The presence of paramagnetic Meissner effect in such devices when field-cooled makes them an excellent candidate to discriminate between the different explanations given for such phenomenon. On the other hand, the understanding of the JJA physics is not simple due to the interplay between the non-linear behaviour of Josephson devices and the mutual induction effects in large JJA. The use of a SQUID microscope (SSM) to catch the magnetic image of the array is a distinctive feature of the experiment. So a study of SQUID read-out based on the actual JJA magnetic behaviour is needed in order to have a correct picture of what is going on. In this paper, using a simple way to reconstruct the complex array far-field viewed by the SQUID, we study how the flux read-out is dependent on array resolution, distance, tilting and noise for the typical situations in which arrays are found. This paper was presented at the 8th International Superconductive Electronics Conference, Osaka, Japan, 19–22 June 2001

We demonstrate that a large area Josephson junction oscillating in the fluxon oscillator mode can be synchronized to other large junctions and simultaneously pump, by emitted radiation, a small area junction. We study the synchronization of the oscillations of the long junctions as a function of relevant experimental parameters such as bias current and stripline coupling characteristics. Experimental results obtained on coupled series arrays of Josephson junctions designed on the basis of our calculations are presented. We have fabricated coupled arrays containing each up to 1500 junctions in order to estimate the usefulness of our calculations for voltage standard devices.

Two-dimensional (2D) Josephson Junctions arrays have been studied largely in the overdamped case. Only recently some experimental, numerical and theoretical results have been obtained in the underdamped case. The nature of dynamical states of an array when placed in a magnetic field is again not fully explained and only approximate (linear) models have been proposed. On the other hand, the comprehension of such dynamics is of great importance for understanding the behavior of such arrays. In this work, we study numerically some of the dynamical states in 2D arrays using a full inductance matrix in the array equations. The results show that the response of the array to the magnetic field is governed at large by the parameter /spl beta//sub L/. Moreover we study the underlying dynamics which is dominated by so-called checkerboard solutions. The properties of such arrays are investigated in view of applications.

We study classical resonant activation (CRA) for a Josephson junction embedded in a shell circuit consisting of one capacitive and one inductive element. The low dissipation quality factor of this device is calculated analytically at the fundamental frequency for two different models of the shell circuit. From our numerical results it emerges that CRA and energy level quantization (ELQ) are distinct processes that can be distinguished in measurements on Josephson devices at low temperatures. CRA at subharmonic frequencies is a highly nonlinear process very different from the corresponding quantum multiphoton process. These results are relevant for the interpretation of a recent experiment on ELQ in high-temperature superconductors Josephson junctions.

A locally phase-shifted Sine–Gordon model well accounts for the phenomenology of unconventional Josephson junctions. The phase dynamics shows resonant modes similar to Fiske modes that appear both in the presence and in the absence of the external magnetic field in standard junctions. In the latter case, they are also in competition with zero field propagation of Sine–Gordon solitons, i.e., fluxons, which give rise to the so-called zero field steps in the current–voltage (I–V) of the junction. We numerically study the I–V characteristics and the resonances magnetic field patterns for some different faceting configurations, in various dissipative regimes, as a function of temperature. The simulated dynamics of the phase is analyzed for lower-order resonances. We give evidence of a nontrivial dynamics due to the interaction of propagating fluxons with localized semifluxons. Numerical results are compared with experimental outcomes obtained on high-quality high-Tc grain boundary YBCO junctions.

We have measured the rate of escape out of the zero-voltage state in Josephson tunnel junctions as a function of the applied magnetic field. A marked difference is found in the behaviour of long and small junctions. In all cases, the statistical distribution of the switching currents can be described using a Kramers model for the escape process, where the barrier to be overcome is the Josephson barrier and the activation energy is due to an effective temperature T/sub e/. For small junctions T/sub e/ coincides, as expected, with the thermodynamic temperature, regardless of the applied magnetic field. For long junctions instead it is found that the escape temperature depends markedly on the magnetic field and on the junction geometry (inline or overlap), suggesting a close relationship with the magnetic field distribution inside the junction.

We report on the study of the phase dynamics of high-critical-temperature superconductor Josephson junctions. We realized YBa${}_{2}$Cu${}_{3}$O${}_{7\ensuremath{-}x}$ grain boundary biepitaxial junctions in the submicron scale using low-loss substrates and analyzed their dissipation by comparing the transport measurements with Monte Carlo simulations. The behavior of the junctions can be fitted using a model based on two quality factors, which results in a frequency-dependent damping. Moreover, our devices can be designed to have Josephson energy of the order of the Coulomb energy. In this unusual energy range, phase delocalization strongly influences the device's dynamics, promoting the transition to a quantum phase diffusion regime. We study the signatures of such a transition by combining the outcomes of Monte Carlo simulations with the analysis of the device's parameters, the critical current, and the temperature behavior of the low-voltage resistance ${R}_{0}$.

The moderately damped regime in a Josephson junction (JJ) is quite common in devices characterized by low critical currents and therefore by low Josephson energies. Measurements of switching current distribution (SCD) are a direct way of discriminating the phase dynamics also in the nontrivial case of moderate damping, which is going to be more and more common with advances in nanopatterning superconductors and in materials science finalized to build hybrid systems. We report on measurements of SCDs, both in thermal and quantum regime, on moderately damped YBaCuO grain boundary biepitaxial JJs. A direct transition from phase diffusion regime to macroscopic quantum tunnelling occurs at about 130 mK. The crossover to the quantum regime is tuned by the magnetic field and phase dynamics is described by a fully consistent set of junction parameters derived through numerical simulations.

The moderately damped regime (MDR) in a Josephson junction (JJ) is quite distinct from the well-known case of underdamped systems and quite common in devices characterized by low critical currents. Measurements of switching current distribution (SCD) are a direct way of discriminating the phase dynamics and the transport also in nontrivial cases of moderate damping. MDR is going to be more and more common with advances in nanopatterning superconductors and in materials science finalized to build hybrid devices. We report on measurements of SCDs, both in the thermal and quantum regime, on moderately damped NbN/MgO/NbN JJs. A transition from the Thermal Activation (TA) regime to Macroscopic Quantum Tunnelling (MQT) occurs at about 90 mK, while above 1.6 K a phase diffusive dynamics is clearly observed. The combined analysis of these regimes through numerical simulations allowed us to extract the fundamental parameters, which completely characterize the phase dynamics of such moderately damped JJs.

International audience; Experiments on very small bubbles showed that classical Gibbs-Laplace theory on surface tension cannot be applied when the dimension of the interface becomes comparable with bubble radi[1]. On the other hand the pressure jump across the interface is from a experimental point of view the most suitable quantity to be measured in order to know surface tension and determine its dependence on curvature. Therefore Laplace formula needs to be generalized to the case of very small bubbles. The theory of second gradient fluids (Germain cf.[2]) accounts the effects of high density gradients (occurring in fluid interface) on fluid pressure. In [3] it is shown that second gradient theory allows the determination of the simplest consistent generalization of Laplace formula and an equivalent bubble theory in which surface tension and radius of a bubble are determined in terms of the density spatial field. This paper complements the quoted results analyzing them numerically. We find that our model: i) predicts the existence of a (minimal) nucleation radius, i.e. a radius which is a minimum possible for the equilibrium of a small bubble; ii) permits, through the new Laplace formula, to evaluate the dependence of surface tension on curvature with results very similar to actual experiments; iii) allows the determination of the range of validity of classical Laplace formula and a theoretical prediction on the departure of experimental data from it.

We report on the occurrence of multiple hopping and retrapping of a Brownian particle in a tilted washboard potential. The escape dynamic has been studied experimentally by measuring the switching current distributions as a function of temperature in a moderately damped NbN/MgO/NbN Josephson junction. At low temperatures the second moment of the distribution increases in agreement with calculations based on Kramers thermal activation regime. After a turn-over temperature T*, the shape of the distributions starts changing and width decreases with temperature. We analyze the data through fit of the switching probability and Monte Carlo simulations and we find a good agreement with a model based on a multiple retrapping process.

High quality epitaxial NbN/MgO/NbN Josephson junctions have been realized with MgO barriers up to a thickness of d = 1 nm. The junction properties coherently scale with the size of barrier, and low critical current densities down to 3 A/cm(2) have been achieved for larger barriers. In this limit, junctions exhibit macroscopic quantum phenomena for temperatures lower than 90 mK. Measurements and junction parameters support the notion of a possible use of these devices for multiphoton quantum experiments, taking advantage of the fast non equilibrium electron-phonon relaxation times of NbN. (C) 2011 American Institute of Physics. [doi:10.1063/1.3624471]

Calculations using the particle-map perturbative approach predict that fluxons in long Josephson junctions can exhibit chaotic motion when the junction is driven by an external microwave signal, applied to the junction via magnetic field boundary conditions. The chaotic state is reached through a Feigenbaum-like cascade in the fluxon times of flight across the junction, with increasing signal amplitudes. In the present work the existence of such chaotic dynamics is demonstrated via numerical integration of the full perturbed sine-Gordon partial differential equation (PDE) model of the junction. The salient characteristics of the PDE dynamics are compared with the results obtained from the perturbative map approach. The resulting PDE chaos appears to be strictly low-dimensional: fluxons retain their shape without loss of spatial coherence, but their temporal motion is chaotic.

We have investigated the static and dynamic properties of long YBa2Cu3O7-delta 0-pi Josephson junctions and compared them with those of conventional 0 junctions. Scanning SQUID microscope imaging has revealed the presence of a semifluxon at the phase discontinuity point in 0-pi Josephson junctions. Zero field steps have been detected in the current-voltage characteristics of all junctions. Comparison with simulation allows us to attribute these steps to fluxons traveling in the junction for conventional 0 junctions and to fluxon-semifluxon interactions in the case of 0-pi Josephson junctions.

Galanin and neuropeptide Y (NPY) are among the most abundant neuropeptides in the hypothalamus. The role of NPY and galanin in the regulation of the secretory activity of the anterior pituitary has been well established. In addition, the two peptides interact with a number of neurons synthesizing the releasing and inhibiting hormones and a large number of other neuropeptides. The aim of the present studies was to explore if, as in rodents, NPY innervates galanin-immunoreactive (IR) neurons in the human diencephalon. Due to the long post mortem period and subsequent lack of optimal preservation of the cell membranes in the brain, electron microscopy could not be employed to show the presence of NPY-IR synapses on galanin-IR neurons. Therefore, we used light microscopic double label immunocytochemistry and high magnification microscopy with oil immersion to identify putative juxtapositions between NPY and galanin. Our studies show that similarly to rats, numerous NPY-IR nerve terminals surrounded galanin-IR neurons in the human hypothalamus. Among the hypothalamic regions, the infundibulum (infundibular or arcuate nucleus) contained the largest number of galanin-IR neurons heavily surrounded with NPY-IR nerve terminals. These en passant-type intimate associations between NPY-IR and galanin-IR neuronal elements may be functional synapses and may provide the morphological basis for the NPY-mediated galanin release. Consequently, NPY-galanin communication may mediate effects of NPY on neuronal systems innervated by galanin, and therefore may play a pivotal role in the regulation of reproduction, growth, energy and metabolism.

Series-biased arrays of long Josephson junction fluxon oscillators can be phase locked by mutual coupling to a high-Q, linear distributed resonator. A simplified model of such a device, consisting of junctions described by the particle-map perturbation theory approach which are capacitively coupled to a lumped, linear tank circuit, reproduce the essential experimental observations at a very low computational cost. A more sophisticated model, consisting of partial differential equation descriptions of the junctions, again mutually coupled to a linear tank, substantially confirm the predictions of the simplified model. In the particle-map model, the locking range in junction bias current increases linearly with the coupling capacitance; in the partial differential equation (p.d.e.) model, this holds up to a certain maximum value of the capacitance, after which a saturation of the locking range is observed. In both models, for a given spread of junction lengths, the existence of a minimum value of the capacitance for locking to a tank with a given resonant frequency is evidenced. Journal of Applied Physics is copyrighted by The American Institute of Physics.

We have investigated the static and dynamic properties of long YBa2Cu3O(7-delta) 0-pi Josephson junctions and compared them with those of conventional 0 junctions. Scanning SQUID microscope imaging has revealed the presence of a semifluxon at the phase discontinuity point in 0-pi Josephson junctions. Zero field steps have been detected in the current-voltage characteristics of all junctions. Comparison with simulation allows us to attribute these steps to fluxons traveling in the junction for conventional 0 junctions and to fluxon-semifluxon interactions in the case of 0-pi Josephson junctions.

Chaotic dynamics in a model of a long Josephson junction (LJJ) is studied via standard techniques of non-linear maps. A characterization of chaos in such objects in terms of Lyapunov exponents and Poincare sections is given. Finally the occurrence of chaos in map dynamics is compared with preliminary results of full numerical integration of the perturbed sine-Gordon equation (PSGE).

The influence of surface-resistance dissipation on phase locking of fluxon oscillations in long Josephson junctions of in-line geometry subjected to microwave fields which interact with the fluxon at the junction boundaries is studied by the perturbation- theory map approach and by full integration of the pde model of the junction.

In highly hysteretic long Josephson junctions irradiated with microwaves the rf-induced current steps can cross the zero-current axis. The quantized voltage states arise from the phase locking of fluxon oscillations, which in rf-driven junctions can occur even with negative current bias. This phenomenon is interesting both for nonlinear dynamics and for application to the Josephson voltage standard.

The status of advancement of the VIRGO Project is presented: the first-generation results from the Pisa seismic noise super attenuator give an upper limit to the noise transfer function of 2 × 10 −8 at 10 Hz. The upper limit to the absolute noise of the 400 kg test mass at 10 Hz has been measured to be 1.5 × 10 −13 m/√Hz. The scheme and the related problems of the VIRGO interferometer, which is supposed to work down to 10 Hz, are also presented. At the 3rd Pisa Meeting in 1986 we presented the idea of what could be a very efficient seismic noise reduction system able to give a sensitivity h ∼ 10 −25 at 10 Hz, in a 3 km interferometer for 1 year integration time. Now we have two new facts to present: the first is that the attenuation has been built, is working in Pisa, and shows remarkable characteristics. The second is the Italian-French interferometer VIRGO [1,2], a 3 km long antenna for low and high frequency (10–1000 Hz) gravitational wave (GW) detection. These two items will be presented in this article.

We study the vortex-vortex and vortex-antivortex interaction in arrays of Josephson junction particularly addressing the effect of mutual induction in the intermediate screening ranges (betaa = 0.5). The modifications of the barrier energy for the displacement of a vortex in presence of a second vortex (antivortex), or more vortices (antivortices), are derived in an "adiabatic" approach. To this end, we have developed a fast explicit algorithm, which permits to retrieve the phases and the magnetization of the array in a reasonable time and with little memory occupation for relatively large arrays [e.g. o(100 times 100)]. This new model is able to catch the essential characters of the more complex "fully mutual coupling" model. We provide also some indications on the relation between energy barriers and the observation of vortex quantum tunneling phenomena in Josephson arrays and related systems as high-TC films.

We have modeled flux quanta propagation in two-dimensional square arrays of small Josephson junctions when the motion is hampered by the presence of an effective barrier due to the superconducting loops. The energy barriers have been estimated simulating the effect of thermal fluctuations and evaluating the barrier via the Arrhenius factor. The results have been compared with a much simpler semianalytic method, showing that the method is able to give an acceptable estimate. The strength of the fluxon-(anti)fluxon interaction as a function of the loop inductance and the distance between the excitations has been also evaluated. It is reported that the presence of a finite inductance substantially affects the interaction potential, and the contributions due to mutual inductances are found to further change the behavior of the interaction.

By introducing a concept of thermal expansion (TE) of a Josephson junction as an elastic response to an effective stress field, we studied (both analytically and numerically) the temperature and magnetic field dependences of the TE coefficient $\ensuremath{\alpha}$ in a single small junction and in a square array. In particular, we found that in addition to field oscillations due to Fraunhofer-type dependence of the critical current, $\ensuremath{\alpha}$ of a small single junction also exhibits strong flux driven temperature oscillations near ${T}_{C}$. We also numerically simulated stress-induced response of a closed loop with finite self-inductance (a prototype of an array) and found that $\ensuremath{\alpha}$ of a $5\ifmmode\times\else\texttimes\fi{}5$ array may still exhibit temperature oscillations provided the applied magnetic field is strong enough to compensate for the screening-induced effects.

The escape rate from the zero voltage state in a superconducting Josephson junction (JJ) is determined by the temperature, but it saturates at low temperature due to macroscopic quantum tunneling (MQT). Complications due to $d$-wave symmetry in a high temperature superconductor, like low energy quasiparticles and an unconventional current-phase relation, may influence the escape rate. We report, for the first time to our knowledge, the observation of MQT in a ${\mathrm{Y}\mathrm{B}\mathrm{a}}_{2}{\mathrm{C}\mathrm{u}}_{3}{\mathrm{O}}_{7\ensuremath{-}\ensuremath{\delta}}$ grain boundary biepitaxial JJ. This proves that dissipation can be significantly reduced by a proper junction configuration, which is of significance for quantum coherence.

The escape rate from the zero voltage state in a superconducting Josephson junction (JJ) is determined by the temperature, but it saturates at low temperature due to macroscopic quantum tunneling (MQT). Complications due to d-wave symmetry in a high temperature superconductor, like low energy quasiparticles and an unconventional current-phase relation, may influence the escape rate. We report, for the first time to our knowledge, the observation of MQT in a YBa(2)Cu(3)O(7-delta) grain boundary biepitaxial JJ. This proves that dissipation can be significantly reduced by a proper junction configuration, which is of significance for quantum coherence.

By irradiating with a single ultrafast laser pulse a superconducting electrode of a Josephson junction it is possible to drive the quasiparticles (qp's) distribution strongly out of equilibrium. The behavior of the Josephson device can, thus, be modified on a fast time scale, shorter than the qp's relaxation time. This could be very useful, in that it allows fast control of Josephson charge qubits and, in general, of all Josephson devices. If the energy released to the top layer contact $S1$ of the junction is of the order of $\sim \mu J$, the coherence is not degradated, because the perturbation is very fast. Within the framework of the quasiclassical Keldysh Green's function theory, we find that the order parameter of $S1$ decreases. We study the perturbed dynamics of the junction, when the current bias is close to the critical current, by integrating numerically its classical equation of motion. The optical ultrafast pulse can produce switchings of the junction from the Josephson state to the voltage state. The switches can be controlled by tuning the laser light intensity and the pulse duration of the Josephson junction., Comment: 17 pages, 5 figures

Recent experiments on high-temperature superconductors show paramagnetic behavior localized at grain boundaries (GB). This paramagnetism can be attributed to the presence unconventional d-wave induced $\pi$-junctions. By modeling the GB as an array of $\pi$ and conventional Josephson junction we determine the conditions of the occurrence of the paramagnetic behavior., Comment: 4 pages, 4 figures, submitted to Phys. Rev. Lett