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Possibilities of various diagnostic methods for biliary hypertension detection in chronic pancreatitis were analyzed. Biliary hypertension was revealed in 163 (31%) patients, suffering chronic pancreatitis. The laboratory investigations data, ultrasonographic investigation, computer tomography, endoscopic retrograde cholangiopancreatography, magnet-resonance cholangiopancreatography, intraoperative measurement of the biliary ducts width, intraoperative measurement of biliary pressure were applied for diagnosis. Endoscopic retrograde cholangiopancreatography, magnet-resonance cholangiopancreatography and intraoperative measurement of biliary pressure are considered the most sensitive methods for chronic pancreatitis diagnosis.

Objective. To estimate the results of performance of extended pancreatic resection in treatment of patients, suffering pancreatic tumors. Маterials and methods. In 2010 – 2016 yrs 545 patients were operated for pancreatic adenocarcinoma, distal pancreatic resection was performed in 127 (23.3%) of them, pancreaticoduodenal resection (PDR) – in 402 (73.8%), total pancreatectomy – in 16 (2.9%). Extended pancreatic resection was performed in 121 (22.2%) patients, including PDR – in 65 (53.7%), pancreatic distal resection – in 46 (38%), pancreatectomy – in 10 (8.3%). Results. Complications have had occurred in 167 (39.4%) patients after standard pancreatic resection and in 51 (42.1%) – after the extended one (c2 = 0.29, p = 0.58). Lethality was 2.6% (14 patients died), of them 5 (4.1%) – after extended pancreatic resection, 9 (2.1%) – a standard one (c2 = 1.52, p = 0.22). Survival median and the general five–year survival indices are nontrustworthy lesser in patients after extended pancreatic resection than after a standard one – 21 mo and 26% and 28 mo and 29% (c2 = 0.15, p = 0.69), accordingly. Conclusion. Lethality, morbidity rate, remote results after extended pancreatic resection are comparable with those after its standard resection.

Experience of surgical treatment of 241 patients with malignant tumor of duodenal major papilla in 1992-2005 yrs was analyzed. In 95 patients the treatment was conducted in two stages, the first of which have had included biliary decompression. There were analyzed 18 potential risk factors for postoperative complications occurrence. Preoperative biliary decompression conduction have had constituted one of the risk factors for postoperative complications occurrence. There were proposed strict recommendations concerning preoperative biliary decompression conduction in patients with malignant tumor of duodenal major papilla.

Results of treatment of 39 patients, to whom pancreatoduodenal resection was performed for periampullar zone tumour, were analyzed. Anemia, revealed before the operation, had constituted the factor, which trustworthily increased the postoperative complications occurrence risk. Therapeutic course, using recombinant erythropoietins, was conducted for correction of anemia in 7 patients. This had promoted the hemoglobin level raising, the risk of postoperative complications occurrence lowering, but did not influence the intraoperative blood loss severity and perioperative hemotransfusion volume.