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1. Additional file 1 of Dynamics of disease characteristics and clinical management of critically ill COVID-19 patients over the time course of the pandemic: an analysis of the prospective, international, multicentre RISC-19-ICU registry

Author

Wendel-Garcia, Pedro David, Moser, André, Jeitziner, Marie-Madlen, Aguirre-Bermeo, Hernán, Arias-Sanchez, Pedro, Apolo, Janina, Roche-Campo, Ferran, Franch-Llasat, Diego, Kleger, Gian-Reto, Schrag, Claudia, Pietsch, Urs, Filipovic, Miodrag, David, Sascha, Stahl, Klaus, Bouaoud, Souad, Ouyahia, Amel, Fodor, Patricia, Locher, Pascal, Siegemund, Martin, Zellweger, Nuria, Cereghetti, Sara, Schott, Peter, Gangitano, Gianfilippo, Wu, Maddalena Alessandra, Alfaro-Farias, Mario, Vizmanos-Lamotte, Gerardo, Ksouri, Hatem, Gehring, Nadine, Rezoagli, Emanuele, Turrini, Fabrizio, Lozano-Gómez, Herminia, Carsetti, Andrea, Rodríguez-García, Raquel, Yuen, Bernd, Weber, Anja Baltussen, Castro, Pedro, Escos-Orta, Jesus Oscar, Dullenkopf, Alexander, Martín-Delgado, Maria C., Aslanidis, Theodoros, Perez, Marie-Helene, Hillgaertner, Frank, Ceruti, Samuele, Franchitti Laurent, Marilene, Marrel, Julien, Colombo, Riccardo, Laube, Marcus, Fogagnolo, Alberto, Studhalter, Michael, Wengenmayer, Tobias, Gamberini, Emiliano, Buerkle, Christian, Buehler, Philipp K., Keiser, Stefanie, Elhadi, Muhammed, Montomoli, Jonathan, Guerci, Philippe, Fumeaux, Thierry, Schuepbach, Reto A., Jakob, Stephan M., Que, Yok-Ai, and Hilty, Matthias Peter

Subjects
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, ComputingMilieux_COMPUTERSANDEDUCATION, Data_FILES, ComputerApplications_COMPUTERSINOTHERSYSTEMS
Abstract

Additional file 1. Online Supplementary Material.

Published
2022
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2. Additional file 1 of Implications of early respiratory support strategies on disease progression in critical COVID-19: a matched subanalysis of the prospective RISC-19-ICU cohort

Author

Garcia, Pedro D. Wendel, Aguirre-Bermeo, Hernán, Buehler, Philipp K., Alfaro-Farias, Mario, Yuen, Bernd, David, Sascha, Tschoellitsch, Thomas, Wengenmayer, Tobias, Korsos, Anita, Fogagnolo, Alberto, Gian-Reto Kleger, Wu, Maddalena A., Colombo, Riccardo, Turrini, Fabrizio, Potalivo, Antonella, Rezoagli, Emanuele, Rodríguez-García, Raquel, Castro, Pedro, Lander-Azcona, Arantxa, Martín-Delgado, Maria C., Lozano-Gómez, Herminia, Ensner, Rolf, Michot, Marc P., Gehring, Nadine, Schott, Peter, Siegemund, Martin, Merki, Lukas, Wiegand, Jan, Jeitziner, Marie M., Laube, Marcus, Salomon, Petra, Hillgaertner, Frank, Dullenkopf, Alexander, Ksouri, Hatem, Cereghetti, Sara, Grazioli, Serge, Bürkle, Christian, Marrel, Julien, Fleisch, Isabelle, Marie-Helene Perez, Weber, Anja Baltussen, Ceruti, Samuele, Marquardt, Katharina, Hübner, Tobias, Redecker, Hermann, Studhalter, Michael, Stephan, Michael, Selz, Daniela, Pietsch, Urs, Ristic, Anette, Heise, Antje, Bentrup, Friederike Meyer Zu, Laurent, Marilene Franchitti, Fodor, Patricia, Gaspert, Tomislav, Haberthuer, Christoph, Colak, Elif, Heuberger, Dorothea M., Fumeaux, Thierry, Montomoli, Jonathan, Guerci, Philippe, Schuepbach, Reto A., Hilty, Matthias P., and Roche-Campo, Ferran

Abstract

Additional file 1. e-Appendix 1: Specifications on the RISC-19-ICU registry structure and data collection. e-Appendix 2: Missing data handling. e-Table 1: Overall “unmatched” baseline characteristics on Day 0. e-Figure 1: “Love Plot” presenting Standardized Mean Differences between the unmatched and matchedcohort. e-Table 2: Demographics, characteristics at ICU admission, progression of respiratory support and outcome; stratified by survivor status. e-Table 3: Progression of respiratory support stratified by respiratory support strategy at ICU admission. e-Figure 2: Temporal relationship between the period of admission to the intensive care unit and the use of respiratory support strategies or mortality rate. e-Figure 3: Kaplan Meier curves for intensive care unit mortality stratified by the period of admission to the intensive care unit. e-Table 4: Demographics, characteristics at ICU admission, progression of respiratory support and outcome for patients never requiring intubation and invasive mechanical ventilation. e-Figure 4: C-Reactive Protein stratified by respiratory support strategy on Day 0 over the first week of ICU stay. e-Table 5: Mixed Effect Model of C-Reactive Protein stratified by respiratory support strategy on Day 0 over the first week of ICU stay. e-Figure 5: Multivariable adjusted COX regression model for the incidence of intubation. e-Figure 6: Multivariable adjusted COX regression model for overall ICU mortality. e-Figure 7: Multivariable adjusted COX regression model for ICU mortality (intubated patients only). e-Figure 8: Multivariable adjusted COX regression model for ICU discharge (intubated patients only). e-Table 6: Prognostic Model for the identification of patients with lower ICU mortality risk after a failed HFNC or NIV trial. e-Figure 9: Nomogram, Receiver Operating Curves and stratified Kaplan Meier curve for a prognostic model identifying patients with lower ICU mortality risk after a failed HFNC or NIV trial. e-Table 7: Area Under the Receiver Operating Curves (AUROCs) for the Prognostic Score versus classic severity scores.

Published
2021
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