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Comparison of cation/anion Associations using Piper plots and principal component analysis

Background: Surgical or percutaneous occlusion of the left atrial appendage (LAA) is increasingly used for thromboembolic protection in atrial fibrillation. Incomplete LAA closure may increase risk of thrombosis and thromboembolism, and therefore approaches to address residual communications are needed. Objective: To analyze the technique of closing an incompletely occluded LAA and subsequent patient outcomes. Methods: We performed a retrospective analysis of 5 consecutive patients who presented for completion of LAA closure. Results: Four patients were male, mean age 75, average CHA2DS2-VASc score 5.4, and four had prior surgical LAA ligation. One patient had previously had a WATCHMAN device placed for whom a 3D printed model was created from preprocedural imaging data to guide Amplatzer occluder device selection for closure. The residual LAA communication maximal diameter averaged 6.2 mm (range 5-8mm). In 4 of 5 cases, an ablation catheter was used to enter the LAA. The residual LAA communication was closed with either an Amplatzer occluder (n=3) or a WATCHMAN device (n=2). No procedural complications occurred, and no residual leak remained afterwards. No neurologic events occurred during follow up (average 603 days, range 155-1177 days). Anticoagulation or dual antiplatelet therapy was stopped following a transesophageal echo (TEE) ³ 6 weeks after the procedure demonstrated no residual communication in 4 of 5 patients, and after 20 weeks in the fifth patient without a follow up TEE. Conclusion: Large residual LAA communications after LAA occlusion attempts can be successfully and safely closed percutaneously using either Amplatzer occluder devices or WATCHMAN devices.

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POLAR 2018 - XXXV SCAR Meetings and SCAR/IASC Open Science Conference, 19-23 June 2018, Davos, Switzerland, Climate warming affects the development and distribution of sea ice south of the Polar Front around Antarctica and its associated ecosystems, but at present the evidence of feedbacks on climate through ecosystem-derived changes in the atmosphere is sparse. The PEGASO cruise visited the Antarctic region of the South Orkney Islands at the northern edge of the Weddell Sea, and the Subantarctic region of the South Georgia Island, in summer 2015. Each region was studied intensively in lagrangian mode over a few days and diel cycles. Oceanic measurements of plankton abundance, diversity, activity and physiology, plus organic matter characteristics, organic volatile compounds (dimethylsulfide, isoprene, halomethanes) and nutrient concentrations, were compared with simultaneous atmospheric measurements of aerosol numbers, size and composition. Samples of surface seawater and melted sea ice were bubbled in an aerosol-generation tank and the characteristics of the sprayed aerosol were monitored. This integrated study allowed to link phytoplankton bloom stages and the emission of aerosol-forming particulate and gaseous substances. For instance, we observed that the microbiota of sea ice and sea ice-influenced ocean are a previously unknown significant source of atmospheric organic nitrogen, including low molecular weight alkyl-amines. Given the keystone role of nitrogen, sulfur, carbon and iodine compounds in aerosol formation, growth and neutralization, our findings call for greater chemical and source diversity in the modeling efforts linking the marine ecosystem to aerosol-mediated climate effects in the Southern Ocean

POLAR 2018 - XXXV SCAR Meetings and SCAR/IASC Open Science Conference, 19-23 June 2018, Davos, Switzerland.-- 1 page, Climate warming affects the development and distribution of sea ice around Antarctica and its associated ecosystems, but at present the evidence of feedbacks on climate through ecosystem-derived changes in the atmosphere is sparse. The PEGASO cruise visited the Antarctic region of the South Orkney Islands at the northern edge of the Weddell Sea, and the Subantarctic region of the South Georgia Island, in summer 2015. Each region was studied intensively in lagrangian mode over a few days and diel cycles. Oceanic measurements of plankton abundance, diversity, activity and physiology, plus organic matter characteristics, aerosol-forming organic volatile compounds (dimethylsulfide, methylamines, isoprene, halomethanes) and nutrient concentrations, were compared with simultaneous atmospheric measurements of aerosol numbers, size and composition. Samples of surface seawater and melted sea ice were bubbled in an aerosol-generation tank and the characteristics of the sprayed aerosol were monitored. This integrated study allowed to link phytoplankton bloom stages and the emission of aerosol-forming particulate and gaseous substances. Our findings call for greater chemical and source diversity in the modeling efforts linking the marine ecosystem to aerosol-mediated climate effects in the Southern Ocean

2018 Ocean Sciences Meeting, 11-16 February, in Portland, Oregon, Climate warming affects the development and distribution of sea ice south of the Polar Front around Antarctica and its associated ecosystems, but at present the evidence of feedbacks on climate through ecosystem-derived changes in the atmosphere is sparse. The PEGASO cruise visited the Antarctic region of the South Orkney Islands at the northern edge of the Weddell Sea, and the Subantarctic region of the South Georgia Island, in summer 2015. Each region was studied intensively in lagrangian mode over a few days and diel cycles. Oceanic measurements of plankton abundance, diversity, activity and physiology, plus organic matter characteristics, organic volatile compounds (dimethylsulfide, isoprene, halomethanes) and nutrient concentrations, were compared with simultaneous atmospheric measurements of aerosol numbers, size and composition. Samples of surface seawater and melted sea ice were bubbled in an aerosol-generation tank and the characteristics of the sprayed aerosol were monitored. This integrated study allowed to link phytoplankton bloom stages and the emission of aerosol-forming particulate and gaseous substances. For instance, we observed that the microbiota of sea ice and sea ice-influenced ocean are a previously unknown significant source of atmospheric organic nitrogen, including low molecular weight alkyl-amines. Given the keystone role of nitrogen, sulfur, carbon and iodine compounds in aerosol formation, growth and neutralization, our findings call for greater chemical and source diversity in the modeling efforts linking the marine ecosystem to aerosol-mediated climate effects in the Southern Ocean

4th Interlab Meeting, 22-23 May 2017, Banyuls-sur-Mer, France, Marine viruses, together with other planktonic microorganisms, play an important role on the marine ecosystem functioning, and their activity can contribute on the marine aerosol composition. During the interdisciplinary PEGASO expedition, we visit four contrasting areas of the Southern Ocean (Antarctic and sub-antarctic), with high (South Giorgia Island) to low degree (Orkney Islands) of microplanktonic biomass and activity and derived secondary compounds concentration. In this study we aimed to (I) describe different viral community abundance and structures (distribution and diversity) among four contrasted areas; (II) relate them with their main hosts (bacteria and phytoplankton) as well as with physicochemical variables and (III) uncover their relation with metabolic secondary compounds generated by marine microbiological activity, which in turn, can be related with the marine aerosol composition