1. Additional file 1 of Clinical implications with tolvaptan on monitored bioimpedance-defined fluid status in patients with cirrhotic ascites: an observational study
- Author
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Shiba, Shunsuke, Po-Sung Chu, Nakamoto, Nobuhiro, Yamataka, Karin, Nobuhito Taniki, Ojiro, Keisuke, Yamaguchi, Akihiro, Morikawa, Rei, Yoshida, Aya, Ikura, Akihiko, Ebinuma, Hirotoshi, Hidetsugu Saito, and Kanai, Takanori
- Abstract
Additional file 1 Figure S1 Inclusion flow of the study subjects. Figure S2 Study schema for tolvaptan administration and the serial monitoring of body compartments and biochemical studies. Figure S3 Serial monitoring of estimated glomerular filtration rate and total bilirubin of the study subjects after add-on tolvaptan at low doses. Figure S4 The resistance-reactance path graphs for responders (panel A) and non-responders (panel B) pre and post add-on tolvaptan at frequency of 50 kHz. Figure S5 Kaplan–Meier analysis for long-term survival as stratified by bioimpedance-defined intracellular water response to add-on tolvaptan in cases without advanced hepatocellular carcinoma. Table S1 Pretreatment clinical characteristics regarding hepatocellular carcinoma and portal hypertension of the study subjects Table S2 Comparison between areas under the receiver operating characteristic curve of clinical parameters for differentiation between responders and non-responders. Table S3 Models of multivariate analysis for predicting the rapid decrease of ICWBIA.
- Published
- 2020
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