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8,663 results on '"Dc"'

1. Inhalant Abuse: Your Child at Risk! Asian Language Initiative.

Author: Office of National Drug Control Policy, Washington, DC.
Abstract: This brochure is aimed at helping Asian American and Pacific Islander adults communicate with young people about the consequences of inhalant abuse. The booklet addresses the issue of preventing youth substance abuse as part of balancing traditional values with American culture. Also explained are symptoms of inhalant use, common names and, most importantly, how to protect kids. Lists of regional and national resources are provided. The publication is presented in Vietnamese, Korean, Cambodian, and Chinese. (GCP)
Published: 2002

2. An olivine cumulate outcrop on the floor of Jezero crater, Mars

Author: Liu, Y, Tice, MM, Schmidt, ME, Treiman, AH, Kizovski, TV, Hurowitz, JA, Allwood, AC, Henneke, J, Pedersen, DAK, VanBommel, SJ, Jones, MWM, Knight, AL, Orenstein, BJ, Clark, BC, Elam, WT, Heirwegh, CM, Barber, T, Beegle, LW, Benzerara, K, Bernard, S, Beyssac, O, Bosak, T, Brown, AJ, Cardarelli, EL, Catling, DC, Christian, Cloutis, EA, Cohen, BA, Davidoff, S, Fairén, AG, Farley, KA, Flannery, DT, Galvin, A, Grotzinger, JP, Gupta, S, Hall, J, Herd, CDK, Hickman-Lewis, K, Hodyss, RP, Horgan, BHN, Johnson, Jørgensen, JL, Kah, LC, Maki, JN, Mandon, L, Mangold, N, McCubbin, FM, McLennan, SM, Moore, K, Nachon, M, Nemere, P, Nothdurft, LD, Núñez, JI, O'Neil, L, Quantin-Nataf, CM, Sautter, V, Shuster, DL, Siebach, KL, Simon, JI, Sinclair, KP, Stack, KM, Steele, A, Tarnas, JD, Tosca, NJ, Uckert, K, Udry, A, Wade, LA, Weiss, BP, Wiens, RC, Williford, KH, Zorzano, M-P, Mangold, Nicolas, Cosmochimie [IMPMC] (IMPMC_COSMO), Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Planétologie et Géosciences [UMR_C 6112] (LPG), Université d'Angers (UA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Laboratoire de Géologie de Lyon - Terre, Planètes, Environnement (LGL-TPE), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut national des sciences de l'Univers (INSU - CNRS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), Liu, Y [0000-0003-0308-0942], Tice, MM [0000-0003-2560-1702], Schmidt, ME [0000-0003-4793-7899], Treiman, AH [0000-0002-8073-2839], Kizovski, TV [0000-0001-8188-9769], Hurowitz, JA [0000-0002-5857-8652], Henneke, J [0000-0002-3195-7417], Pedersen, DAK [0000-0001-7182-8567], VanBommel, SJ [0000-0002-6565-0827], Jones, MWM [0000-0002-0720-8715], Knight, AL [0000-0001-6832-8190], Orenstein, BJ [0000-0002-6586-4227], Clark, BC [0000-0002-5546-8757], Beegle, LW [0000-0002-4944-4353], Benzerara, K [0000-0002-0553-0137], Bernard, S [0000-0001-5576-7020], Beyssac, O [0000-0001-8879-4762], Bosak, T [0000-0001-5179-5323], Brown, AJ [0000-0002-9352-6989], Cardarelli, EL [0000-0001-5451-2309], Catling, DC [0000-0001-5646-120X], Christian, JR [0000-0003-4646-2852], Cloutis, EA [0000-0001-7301-0929], Cohen, BA [0000-0001-5896-5903], Davidoff, S [0000-0002-4417-7268], Fairén, AG [0000-0002-2938-6010], Flannery, DT [0000-0001-8982-496X], Grotzinger, JP [0000-0001-9324-1257], Gupta, S [0000-0001-6415-1332], Hall, J [0000-0003-0884-3777], Herd, CDK [0000-0001-5210-4002], Hickman-Lewis, K [0000-0001-8014-233X], Hodyss, RP [0000-0002-6523-3660], Horgan, BHN [0000-0001-6314-9724], Johnson, JR [0000-0002-5586-4901], Jørgensen, JL [0000-0002-0343-239X], Kah, LC [0000-0001-7172-2033], Maki, JN [0000-0002-7887-0343], Mandon, L [0000-0002-9310-0742], Mangold, N [0000-0002-0022-0631], McCubbin, FM [0000-0002-2101-4431], McLennan, SM [0000-0003-4259-7178], Nachon, M [0000-0003-0417-7076], Nothdurft, LD [0000-0001-9646-9070], Núñez, JI [0000-0003-0930-6674], O'Neil, L [0000-0003-1555-8229], Quantin-Nataf, CM [0000-0002-8313-8595], Shuster, DL [0000-0003-2507-9977], Siebach, KL [0000-0002-6628-6297], Simon, JI [0000-0002-3969-8958], Sinclair, KP [0000-0001-6261-4591], Stack, KM [0000-0003-3444-6695], Steele, A [0000-0001-9643-2841], Tarnas, JD [0000-0002-6256-0826], Tosca, NJ [0000-0003-4415-4231], Uckert, K [0000-0002-0859-5526], Udry, A [0000-0002-0074-8110], Wade, LA [0000-0001-8254-8181], Weiss, BP [0000-0003-3113-3415], Wiens, RC [0000-0002-3409-7344], Zorzano, M-P [0000-0002-4492-9650], and Apollo - University of Cambridge Repository
Subjects: [SDU.STU.PL]Sciences of the Universe [physics]/Earth Sciences/Planetology, Multidisciplinary, 5101 Astronomical Sciences, 37 Earth Sciences, 3705 Geology, 5109 Space Sciences, [SDU.STU.PL] Sciences of the Universe [physics]/Earth Sciences/Planetology, 51 Physical Sciences, 3703 Geochemistry
Abstract: International audience; The geological units on the floor of Jezero crater, Mars, are part of a wider regional stratigraphy of olivine-rich rocks, which extends well beyond the crater. We investigate the petrology of olivine and carbonate-bearing rocks of the Séítah formation in the floor of Jezero. Using multispectral images and x-ray fluorescence data, acquired by the Perseverance rover, we performed a petrographic analysis of the Bastide and Brac outcrops within this unit. We find that these outcrops are composed of igneous rock, moderately altered by aqueous fluid. The igneous rocks are mainly made of coarse-grained olivine, similar to some Martian meteorites. We interpret them as an olivine cumulate, formed by settling and enrichment of olivine through multi-stage cooling of a thick magma body.
Published: 2022
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3. Dobro Dosli U Sjedinjene Drzave. Prirucnik za Izbjeglice. (Welcome to the United States. A Guidebook for Refugees).

Author: Center for Applied Linguistics, Washington, DC. Refugee Service Center.
Abstract: This guidebook provides Bosnian, Croatian, and Serbian refugees being resettled in the United States with general information about what they will encounter and the services they can receive in their first months in the country. The book is distributed to overseas processing agencies, refugees overseas who have been approved for U.S. admission, and service providers. Refugees are advised that most Americans value self-reliance and individual responsibility, but that in general people respect those who ask questions about the new culture they are entering. All refugees are assigned to a relocation agency as they arrive in the United States, and housing is made available for the first month. The following topics are addressed: (1) pre-arrival processing; (2) the role of the resettlement agency; (3) community services; (4) housing; (5) transportation; (6) employment; (7) education; (8) health; (9) managing your money; (10) rights and responsibilities of refugees; and (11) cultural adjustment. Among the topics discussed is that of the American educational system, both for children and adults. A general outline of the public school system includes a discussion of the American tradition of public participation in education. A map of the United States is included. (SLD)
Published: 1996

4. PHARMACOGNOSTIC AND PHARMACOLOGICAL PROPERTIES OF GAMBHARI FRUIT (GMELINA ARBOREA ROXB.): A REVIEW

Author: Radhika Kumiya, DC Singh, GM Kavya, and Kiran Vashisht
Subjects: Drug Discovery, Pharmaceutical Science
Abstract: Gmelina arborea Roxb. is one of the famous medicinal plants of the family Lamiaceae, which different Ayurvedic physicians widely prescribed as a drug of choice for treating many diseases. This drug is commonly named “Kashmarya” and is one of the popular medicinal plants mentioned in all classical textbooks of Ayurveda. It is also known as “Gambhari” because of its fast-growing property, and it is a widely propagated and cultivated tree that grows throughout India. In the Dashamoola groups of herbs, Gambhari (Gmelina arborea Roxb) is one of the components. In Ayurvedic classical textbooks, different plant parts, like roots, fruit, leaf, flower, and bark, can be used medicinally. The edible fruits of Gambhari bear rejuvenating, brain tonic and aphrodisiac qualities. The leaf of Gambhari has been mentioned in the diseases like vrana (wounds) and Kushtha (Skin diseases). The classical part of the plant Gambhari is the root. The present article provides insight into the literature review of the Gambhari fruit. The current manuscript compiles extensive information about Gambhari (Gmelina arborea Roxb.) fruit which is well-mentioned in most Ayurvedic classics textbooks like Brihatrayee, Laghutree and Nighantu.
Published: 2023
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5. Observation of anti-damping spin–orbit torques generated by in-plane and out-of-plane spin polarizations in MnPd3

Author: Mahendra DC, Ding-Fu Shao, Vincent D.-H. Hou, Arturas Vailionis, P. Quarterman, Ali Habiboglu, M. B. Venuti, Fen Xue, Yen-Lin Huang, Chien-Min Lee, Masashi Miura, Brian Kirby, Chong Bi, Xiang Li, Yong Deng, Shy-Jay Lin, Wilman Tsai, Serena Eley, Wei-Gang Wang, Julie A. Borchers, Evgeny Y. Tsymbal, and Shan X. Wang
Subjects: Mechanics of Materials, Mechanical Engineering, General Materials Science, General Chemistry, Condensed Matter Physics
Published: 2023
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6. Signatures of aerosol-induced decline in evapotranspiration over the Indo-Gangetic Plain during the recent decades

Author: MVS Ramarao, DC Ayantika, R Krishnan, J Sanjay, TP Sabin, M Mujumdar, and KK Singh
Subjects: Atmospheric Science, Geophysics
Abstract: Evapotranspiration (ET) is the primary process of water transfer in the hydrological cycle over land and is linked to water, energy and carbon cycles. While the global hydrological cycle is expected to intensify in a warming climate with enhanced ET and precipitation, the magnitude and spatial distribution of regional scale response of ET to climate change remains uncertain. Here we present an analysis of in-situ observations of ET from 23 stations in India during 1979-2008, which shows that the annual ET has declined by about 9% over the humid sub-regions of the Indo-Gangetic Plain (IGP). Additional analysis from high-resolution climate model simulations and observed climate datasets lend support to the role of aerosol-induced solar-dimming in intensifying ET reductions, in a background of decreasing monsoon precipitation and soil-moisture levels, over the IGP
Published: 2023
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7. Faculty Wellness of a Higher Education Institution in the New Normal Time: Basis for the Personal and Professional Development Program

Author: Cecilia A. Geronimo, Romeo DC. Inasoria, Audie L. Geronimo, Deane Genevive G. Geronimo, and Renalyn C. Esguerra
Subjects: General Engineering, Energy Engineering and Power Technology
Abstract: This study aimed to describe the status of faculty wellness in terms of the eight dimensions of wellness such as emotional, environmental, financial, intellectual, occupational, physical, social, and spiritual. Also, the challenges encountered by the faculty on the eight dimensions of wellness during the new normal time. The mixed methods of research were utilized, the constructed and validated questionnaire were responded by 277 faculty members of the HEI and ten randomly selected faculty members were interviewed. The results reveal that the physical wellness got the rating of occasionally while the other seven wellness got the rating of frequently, which implies that majority of the faculty were frequently practicing or doing the item descriptions of the eight dimensions of wellness. For the challenges encountered, the findings show that the spiritual challenge had a rating of seldom while the other ten challenges got the rating of sometimes, which means that the faculty encountered most of the challenges on the other seven dimensions of wellness, and the ranked first three were physical, occupational, and social. The results of the interview present the faculty’s good and not that good experiences with coping mechanisms during the new normal time. The researchers concluded that the status of the eight dimensions of faculty wellness should always be checked and monitored to maintain a smart, healthy, and responsive faculty. Eight personal and professional development programs were proposed to maintain and enhance the faculty wellness of the faculty in the HEI.
Published: 2023
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8. Search for Higgs boson pair production in association with a vector boson in pp collisions at √s=13TeV with the ATLAS detector

Author: Aad, G, Abbott, B, Abbott, DC, Abeling, K, Abidi, SH, Aboulhorma, A, Abramowicz, H, Abreu, H, Abulaiti, Y, Hoffman, ACA, Acharya, BS, Achkar, B, Bourdarios, CA, Adamczyk, L, Adamek, L, Addepalli, SV, Adelman, J, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agaras, MN, Agarwala, J, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmad, A, Ahmadov, F, Ahmed, WS, Ahuja, S, Ai, X, Aielli, G, Aizenberg, I, Akbiyik, M, Åkesson, TPA, Akimov, AV, Khoury, KA, Alberghi, GL, Albert, J, Albicocco, P, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Ali, S, Aliev, M, Alimonti, G, Alkakhi, W, Allaire, C, Allbrooke, BMM, Allport, PP, Aloisio, A, Alonso, F, Alpigiani, C, Camelia, EA, Estevez, MA, Alviggi, MG, Aly, M, Coutinho, YA, Ambler, A, Amelung, C, Amerl, M, Ames, CG, Amidei, D, Santos, SPAD, Amoroso, S, Amos, KR, Ananiev, V, Anastopoulos, C, Andeen, T, Anders, JK, Andrean, SY, Andreazza, A, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antipov, E, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aoki, T, Pozo, JAA, Aparo, MA, Bella, LA, Appelt, C, Aranzabal, N, Ferraz, VA, Arcangeletti, C, Arce, ATH, Arena, E, Aad, G [0000-0002-6665-4934], Abbott, B [0000-0002-5888-2734], Abbott, DC [0000-0002-7248-3203], Abeling, K [0000-0002-1002-1652], Abidi, SH [0000-0002-8496-9294], Aboulhorma, A [0000-0002-9987-2292], Abramowicz, H [0000-0001-5329-6640], Abreu, H [0000-0002-1599-2896], Abulaiti, Y [0000-0003-0403-3697], Hoffman, ACA [0000-0003-0762-7204], Acharya, BS [0000-0002-8588-9157], Achkar, B [0000-0002-0288-2567], Bourdarios, CA [0000-0002-2634-4958], Adamczyk, L [0000-0002-5859-2075], Adamek, L [0000-0003-1562-3502], Addepalli, SV [0000-0002-2919-6663], Adelman, J [0000-0002-1041-3496], Adiguzel, A [0000-0001-6644-0517], Adorni, S [0000-0003-3620-1149], Adye, T [0000-0003-0627-5059], Affolder, AA [0000-0002-9058-7217], Afik, Y [0000-0001-8102-356X], Agaras, MN [0000-0002-4355-5589], Agarwala, J [0000-0002-4754-7455], Aggarwal, A [0000-0002-1922-2039], Agheorghiesei, C [0000-0003-3695-1847], Aguilar-Saavedra, JA [0000-0002-5475-8920], Ahmad, A [0000-0001-8638-0582], Ahmed, WS [0000-0003-0128-3279], Ahuja, S [0000-0003-4368-9285], Ai, X [0000-0003-3856-2415], Aielli, G [0000-0002-0573-8114], Aizenberg, I [0000-0003-2150-1624], Akbiyik, M [0000-0002-7342-3130], Åkesson, TPA [0000-0003-4141-5408], Akimov, AV [0000-0002-2846-2958], Khoury, KA [0000-0002-0547-8199], Alberghi, GL [0000-0003-2388-987X], Albert, J [0000-0003-0253-2505], Albicocco, P [0000-0001-6430-1038], Alderweireldt, S [0000-0002-8224-7036], Aleksa, M [0000-0002-1936-9217], Aleksandrov, IN [0000-0001-7381-6762], Alexa, C [0000-0003-0922-7669], Alexopoulos, T [0000-0002-8977-279X], Alfonsi, A [0000-0001-7406-4531], Alfonsi, F [0000-0002-0966-0211], Alhroob, M [0000-0001-7569-7111], Ali, B [0000-0001-8653-5556], Ali, S [0000-0001-5216-3133], Aliev, M [0000-0002-9012-3746], Alimonti, G [0000-0002-7128-9046], Alkakhi, W [0000-0001-9355-4245], Allaire, C [0000-0003-4745-538X], Allbrooke, BMM [0000-0002-5738-2471], Allport, PP [0000-0001-7303-2570], Aloisio, A [0000-0002-3883-6693], Alonso, F [0000-0001-9431-8156], Alpigiani, C [0000-0002-7641-5814], Estevez, MA [0000-0002-8181-6532], Alviggi, MG [0000-0003-0026-982X], Aly, M [0000-0003-3043-3715], Coutinho, YA [0000-0002-1798-7230], Ambler, A [0000-0003-2184-3480], Amerl, M [0000-0003-1155-7982], Ames, CG [0000-0002-2126-4246], Amidei, D [0000-0002-6814-0355], Santos, SPAD [0000-0001-7566-6067], Amoroso, S [0000-0001-5450-0447], Amos, KR [0000-0003-1757-5620], Ananiev, V [0000-0003-3649-7621], Anastopoulos, C [0000-0003-1587-5830], Andeen, T [0000-0002-4413-871X], Anders, JK [0000-0002-1846-0262], Andrean, SY [0000-0002-9766-2670], Andreazza, A [0000-0001-5161-5759], Angelidakis, S [0000-0002-8274-6118], Angerami, A [0000-0001-7834-8750], Anisenkov, AV [0000-0002-7201-5936], Annovi, A [0000-0002-4649-4398], Antel, C [0000-0001-9683-0890], Anthony, MT [0000-0002-5270-0143], Antipov, E [0000-0002-6678-7665], Antonelli, M [0000-0002-2293-5726], Antrim, DJA [0000-0001-8084-7786], Anulli, F [0000-0003-2734-130X], Aoki, M [0000-0001-7498-0097], Aoki, T [0000-0002-6618-5170], Pozo, JAA [0000-0001-7401-4331], Aparo, MA [0000-0003-4675-7810], Bella, LA [0000-0003-3942-1702], Appelt, C [0000-0003-1205-6784], Aranzabal, N [0000-0001-9013-2274], Ferraz, VA [0000-0003-1177-7563], Arcangeletti, C [0000-0001-8648-2896], Arce, ATH [0000-0002-7255-0832], Arena, E [0000-0001-5970-8677], and Apollo - University of Cambridge Repository
Subjects: 51 Physical Sciences, 5107 Particle and High Energy Physics
Abstract: This paper reports a search for Higgs boson pair (hh) production in association with a vector boson ($$W\; {\text {o}r}\; Z$$ W o r Z ) using 139 fb$$^{-1}$$ - 1 of proton–proton collision data at $$\sqrt{s}=13\,\text {TeV}$$ s = 13 TeV recorded with the ATLAS detector at the Large Hadron Collider. The search is performed in final states in which the vector boson decays leptonically ($$W\rightarrow \ell \nu ,\, Z\rightarrow \ell \ell ,\nu \nu $$ W → ℓ ν , Z → ℓ ℓ , ν ν with $$\ell =e, \mu $$ ℓ = e , μ ) and the Higgs bosons each decay into a pair of b-quarks. It targets Vhh signals from both non-resonant hh production, present in the Standard Model (SM), and resonant hh production, as predicted in some SM extensions. A 95% confidence-level upper limit of 183 (87) times the SM cross-section is observed (expected) for non-resonant Vhh production when assuming the kinematics are as expected in the SM. Constraints are also placed on Higgs boson coupling modifiers. For the resonant search, upper limits on the production cross-sections are derived for two specific models: one is the production of a vector boson along with a neutral heavy scalar resonance H, in the mass range 260–1000 GeV, that decays into hh, and the other is the production of a heavier neutral pseudoscalar resonance A that decays into a Z boson and H boson, where the A boson mass is 360–800 GeV and the H boson mass is 260–400 GeV. Constraints are also derived in the parameter space of two-Higgs-doublet models.
Published: 2023

9. Constraints on spin-0 dark matter mediators and invisible Higgs decays using ATLAS 13 TeV pp collision data with two top quarks and missing transverse momentum in the final state

Author: Aad, G, Abbott, B, Abbott, DC, Abeling, K, Abidi, SH, Aboulhorma, A, Abramowicz, H, Abreu, H, Abulaiti, Y, Hoffman, ACA, Acharya, BS, Achkar, B, Adam, L, Bourdarios, CA, Adamczyk, L, Adamek, L, Addepalli, SV, Adelman, J, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agaras, MN, Agarwala, J, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmad, A, Ahmadov, F, Ahmed, WS, Ai, X, Aielli, G, Aizenberg, I, Akbiyik, M, Åkesson, TPA, Akimov, AV, Khoury, KA, Alberghi, GL, Albert, J, Albicocco, P, Verzini, MJA, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Ali, S, Aliev, M, Alimonti, G, Allaire, C, Allbrooke, BMM, Allport, PP, Aloisio, A, Alonso, F, Alpigiani, C, Camelia, EA, Estevez, MA, Alviggi, MG, Coutinho, YA, Ambler, A, Amelung, C, Ames, CG, Amidei, D, Santos, SPAD, Amoroso, S, Amos, KR, Amrouche, CS, Ananiev, V, Anastopoulos, C, Andari, N, Andeen, T, Anders, JK, Andrean, SY, Andreazza, A, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antipov, E, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Pozo, JAA, Aparo, MA, Bella, LA, Appelt, C, Aranzabal, N, Ferraz, VA, Arcangeletti, C, Arce, ATH, Arena, E, Arguin, JF, Aad, G [0000-0002-6665-4934], Abbott, B [0000-0002-5888-2734], Abbott, DC [0000-0002-7248-3203], Abeling, K [0000-0002-1002-1652], Abidi, SH [0000-0002-8496-9294], Aboulhorma, A [0000-0002-9987-2292], Abramowicz, H [0000-0001-5329-6640], Abreu, H [0000-0002-1599-2896], Abulaiti, Y [0000-0003-0403-3697], Hoffman, ACA [0000-0003-0762-7204], Acharya, BS [0000-0002-8588-9157], Achkar, B [0000-0002-0288-2567], Adam, L [0000-0001-6005-2812], Bourdarios, CA [0000-0002-2634-4958], Adamczyk, L [0000-0002-5859-2075], Adamek, L [0000-0003-1562-3502], Addepalli, SV [0000-0002-2919-6663], Adelman, J [0000-0002-1041-3496], Adiguzel, A [0000-0001-6644-0517], Adorni, S [0000-0003-3620-1149], Adye, T [0000-0003-0627-5059], Affolder, AA [0000-0002-9058-7217], Afik, Y [0000-0001-8102-356X], Agaras, MN [0000-0002-4355-5589], Agarwala, J [0000-0002-4754-7455], Aggarwal, A [0000-0002-1922-2039], Agheorghiesei, C [0000-0003-3695-1847], Aguilar-Saavedra, JA [0000-0002-5475-8920], Ahmad, A [0000-0001-8638-0582], Ahmed, WS [0000-0003-0128-3279], Ai, X [0000-0003-3856-2415], Aielli, G [0000-0002-0573-8114], Aizenberg, I [0000-0003-2150-1624], Akbiyik, M [0000-0002-7342-3130], Åkesson, TPA [0000-0003-4141-5408], Akimov, AV [0000-0002-2846-2958], Khoury, KA [0000-0002-0547-8199], Alberghi, GL [0000-0003-2388-987X], Albert, J [0000-0003-0253-2505], Albicocco, P [0000-0001-6430-1038], Verzini, MJA [0000-0003-2212-7830], Alderweireldt, S [0000-0002-8224-7036], Aleksa, M [0000-0002-1936-9217], Aleksandrov, IN [0000-0001-7381-6762], Alexa, C [0000-0003-0922-7669], Alexopoulos, T [0000-0002-8977-279X], Alfonsi, A [0000-0001-7406-4531], Alfonsi, F [0000-0002-0966-0211], Alhroob, M [0000-0001-7569-7111], Ali, B [0000-0001-8653-5556], Ali, S [0000-0001-5216-3133], Aliev, M [0000-0002-9012-3746], Alimonti, G [0000-0002-7128-9046], Allaire, C [0000-0003-4745-538X], Allbrooke, BMM [0000-0002-5738-2471], Allport, PP [0000-0001-7303-2570], Aloisio, A [0000-0002-3883-6693], Alonso, F [0000-0001-9431-8156], Alpigiani, C [0000-0002-7641-5814], Estevez, MA [0000-0002-8181-6532], Alviggi, MG [0000-0003-0026-982X], Coutinho, YA [0000-0002-1798-7230], Ambler, A [0000-0003-2184-3480], Ames, CG [0000-0002-2126-4246], Amidei, D [0000-0002-6814-0355], Santos, SPAD [0000-0001-7566-6067], Amoroso, S [0000-0001-5450-0447], Amos, KR [0000-0003-1757-5620], Ananiev, V [0000-0003-3649-7621], Anastopoulos, C [0000-0003-1587-5830], Andari, N [0000-0002-4935-4753], Andeen, T [0000-0002-4413-871X], Anders, JK [0000-0002-1846-0262], Andrean, SY [0000-0002-9766-2670], Andreazza, A [0000-0001-5161-5759], Angelidakis, S [0000-0002-8274-6118], Angerami, A [0000-0001-7834-8750], Anisenkov, AV [0000-0002-7201-5936], Annovi, A [0000-0002-4649-4398], Antel, C [0000-0001-9683-0890], Anthony, MT [0000-0002-5270-0143], Antipov, E [0000-0002-6678-7665], Antonelli, M [0000-0002-2293-5726], Antrim, DJA [0000-0001-8084-7786], Anulli, F [0000-0003-2734-130X], Aoki, M [0000-0001-7498-0097], Pozo, JAA [0000-0001-7401-4331], Aparo, MA [0000-0003-4675-7810], Bella, LA [0000-0003-3942-1702], Appelt, C [0000-0003-1205-6784], Aranzabal, N [0000-0001-9013-2274], Ferraz, VA [0000-0003-1177-7563], Arcangeletti, C [0000-0001-8648-2896], Arce, ATH [0000-0002-7255-0832], Arena, E [0000-0001-5970-8677], Arguin, JF [0000-0003-0229-3858], and Apollo - University of Cambridge Repository
Subjects: 5106 Nuclear and Plasma Physics, 51 Physical Sciences, 5107 Particle and High Energy Physics
Abstract: This paper presents a statistical combination of searches targeting final states with two top quarks and invisible particles, characterised by the presence of zero, one or two leptons, at least one jet originating from a b-quark and missing transverse momentum. The analyses are searches for phenomena beyond the Standard Model consistent with the direct production of dark matter in pp collisions at the LHC, using 139 fb$$^{-\text {1}}$$ - 1 of data collected with the ATLAS detector at a centre-of-mass energy of 13 TeV. The results are interpreted in terms of simplified dark matter models with a spin-0 scalar or pseudoscalar mediator particle. In addition, the results are interpreted in terms of upper limits on the Higgs boson invisible branching ratio, where the Higgs boson is produced according to the Standard Model in association with a pair of top quarks. For scalar (pseudoscalar) dark matter models, with all couplings set to unity, the statistical combination extends the mass range excluded by the best of the individual channels by 50 (25) GeV, excluding mediator masses up to 370 GeV. In addition, the statistical combination improves the expected coupling exclusion reach by 14% (24%), assuming a scalar (pseudoscalar) mediator mass of 10 GeV. An upper limit on the Higgs boson invisible branching ratio of 0.38 ($$\text {0.30}^{+\text {0.13}}_{-\text {0.09}}$$ 0.30 - 0.09 + 0.13 ) is observed (expected) at 95% confidence level.
Published: 2023

10. Effect of Salivary Flow on Bleached Enamel Roughness and Mineral Content: anIn SituandIn VitroStudy

Author: DD Hauss Monteiro, DC Elias, RFO Costa, MFF Carvalho, RC Ferreira, AN Moreira, and CS Magalhães
Subjects: General Dentistry
Abstract: SUMMARYThis study aimed to evaluate the effect of human saliva in vitro and salivary flow in situ on the roughness and mineral content of bleached enamel. Dental specimens were divided into five groups (n=15): not bleached (NB); bleached (35% hydrogen peroxide) and exposed to distilled water (DW); human saliva in vitro (IV); normal salivary flow in situ (NSF); and low salivary flow (LSF) in situ. Enamel roughness (Ra, Rz) and calcium/phosphorus contents were evaluated with laser profilometry and energy-dispersive spectroscopy, respectively, at baseline (T1), after bleaching (T2), and after seven days (T3). Salivary pH and buffer capacity were evaluated with colorimetric strips and salivary calcium and phosphorus with absorbance spectrophotometry. Data were analyzed with non-parametric tests and linear regression (α=0.05). After contact with saliva, Ra and Rz of LSF=DW>IV=NSF=NB was found. For DW and LSF, the roughness of T1
Published: 2023
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11. Malformed individuals of the trilobite Estaingia bilobata from the Cambrian Emu Bay Shale and their palaeobiological implications

Author: Russell DC Bicknell, James D Holmes, Diego C García-Bellido, and John R Paterson
Subjects: Geology
Abstract: Malformed trilobite specimens present important insight into understanding how this extinct arthropod group recovered from developmental or moulting malfunctions, pathologies, and injuries. Previously documented examples of malformed trilobite specimens are often considered in isolation, with few studies reporting on multiple malformations in the same species. Here we report malformed specimens of the ellipsocephaloid trilobite Estaingia bilobata from the Emu Bay Shale Konservat-Lagerstätte (Cambrian Series 2, Stage 4) on Kangaroo Island, South Australia. Ten malformed specimens exhibiting injuries, pathologies, and a range of teratologies are documented. Furthermore, five examples of mangled exoskeletons are presented, indicative of predation on E. bilobata. Considering the position of malformed and normal specimens of E. bilobata in bivariate space, we demonstrate that the majority of malformed specimens cluster among the larger individuals. Such specimens may exemplify larger forms successfully escaping predation attempts, but could equally represent individuals exhibiting old injuries that were made during earlier (smaller) growth stages that have healed through subsequent moulting events. The available evidence from the Emu Bay Shale suggests that this small, extremely abundant trilobite likely played an important role in the structure of the local ecosystem, occupying a low trophic level and being preyed upon by multiple durophagous arthropods. Furthermore, the scarcity of malformed E. bilobata specimens demonstrates how rarely injuries, developmental malfunctions, and pathological infestations occurred within the species.
Published: 2023
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12. A Self-Assessment: Stress and Teaching Health

Author: Reynaldo DC. del Rosario
Subjects: General Medicine
Published: 2023
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13. Antimicrobial activities of nano-emulsion of virgin coconut oil

Author: Widianingrum DC, H Khasanah, L Purnamasari, Krismaputri ME, and Hwang SG
Subjects: General Veterinary
Published: 2023
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14. Estimating North Atlantic right whale prey based on Calanus finmarchicus thresholds

Author: CH Ross, JA Runge, JJ Roberts, DC Brady, B Tupper, and NR Record
Subjects: Ecology, Aquatic Science, Ecology, Evolution, Behavior and Systematics
Abstract: The planktonic copepod Calanus finmarchicus is a fundamental prey resource for the critically endangered North Atlantic right whale Eubalaena glacialis. Incorporation of prey information into E. glacialis decision support tools could improve management. Zooplankton time series are usually analyzed with respect to abundance, but predators such as E. glacialis forage based on whether prey aggregations exceed energetic thresholds. In order to better understand the distribution and dynamics of the high-abundance end of C. finmarchicus on the northeastern US continental shelf, where E. glacialis feed, we modeled the environmental conditions associated with C. finmarchicus densities that exceed nominal feeding thresholds. Threshold values were chosen based on a review of E. glacialis feeding behavior throughout the domain. Following model selection procedures, we used a random forest model with bathymetry, bottom temperature, bottom salinity, day of year, sea surface temperature, sea surface temperature gradient, bathymetric slope, time-integrated chlorophyll, current velocity gradient, and wind covariates. Model performance was highest with thresholds that matched reported E. glacialis feeding thresholds equivalent to 10000 copepods m-2. The high-density aggregations of C. finmarchicus had some different covariate responses compared to previous statistical abundance models, such as a warmer temperature range at both the surface and at depth, as well as a much higher degree of spatial variability. The output data layers of the model are designed to link with E. glacialis models used in US governmental decision support tools. Including this type of foraging information in decision support tools is a step forward in managing this critically endangered species.
Published: 2023
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15. Frailty and Mortality Risk in COPD: A Cohort Study Comparing the Fried Frailty Phenotype and Short Physical Performance Battery

Author: Lisa Jane Brighton, Claire M Nolan, Ruth E Barker, Suhani Patel, Jessica A Walsh, Oliver Polgar, Samantha SC Kon, Wei Gao, Catherine J Evans, Matthew Maddocks, and William DC Man
Subjects: frailty, General Medicine, International Journal of Chronic Obstructive Pulmonary Disease, survival, Respiratory disease, chronic obstructive pulmonary disease
Abstract: Lisa Jane Brighton,1 Claire M Nolan,2,3 Ruth E Barker,2,4,5 Suhani Patel,2,4 Jessica A Walsh,2 Oliver Polgar,2 Samantha SC Kon,2,4,6 Wei Gao,1 Catherine J Evans,1,7 Matthew Maddocks,1 William DC Man2,4,8,9 1Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Kingâs College London, London, UK; 2Harefield Respiratory Research Group, Royal Brompton and Harefield Hospitals, Guyâs and St Thomas NHS Foundation Trust, London, UK; 3Division of Physiotherapy, College of Health, Medicine and Life Sciences, Brunel University London, London, UK; 4National Heart and Lung Institute, Imperial College, London, UK; 5Insight Innovation, Wessex Academic Health Science Network, Southampton, UK; 6Department of Respiratory Medicine, The Hillingdon Hospital NHS Trust, London, UK; 7Brighton General Hospital, Sussex Community NHS Foundation Trust, Brighton, UK; 8Harefield Pulmonary Rehabilitation Unit, Guyâs and St Thomas NHS Foundation Trust, London, UK; 9Faculty of Life Sciences & Medicine, Kingâs College London, London, UKCorrespondence: Lisa Jane Brighton, Cicely Saunders Institute, Bessemer Road, Denmark Hill, London, SE5 9PJ, UK, Tel +44 020 7848 5041, Email lisa.brighton@kcl.ac.ukBackground: Identifying frailty in people with chronic obstructive pulmonary disease (COPD) is deemed important, yet comparative characteristics of the most commonly used frailty measures in COPD are unknown. This study aimed to compare how the Fried Frailty Phenotype (FFP) and Short Physical Performance Battery (SPPB) characterise frailty in people with stable COPD, including prevalence of and overlap in identification of frailty, disease and health characteristics of those identified as living with frailty, and predictive value in relation to survival time.Methods: Cohort study of people with stable COPD attending outpatient clinics. Agreement between frailty classifications was described using Cohenâs Kappa. Disease and health characteristics of frail versus not frail participants were compared using t-, MannâWhitney U and Chi-Square tests. Predictive value for mortality was examined with multivariable Cox regression.Results: Of 714 participants, 421 (59%) were male, mean age 69.9 years (SD 9.7), mean survival time 2270 days (95% CI 2185â 2355). Similar proportions were identified as frail using the FFP (26.2%) and SPPB (23.7%) measures; classifications as frail or not frail matched in 572 (80.1%) cases, showing moderate agreement (Kappa = 0.469, SE = 0.038, p < 0.001). Discrepancies seemed driven by FFP exhaustion and weight loss criteria and the SPPB balance component. People with frailty by either measure had worse exercise capacity, health-related quality of life, breathlessness, depression and dependence in activities of daily living. In multivariable analysis controlling for the Age Dyspnoea Obstruction index, sex, BMI, comorbidities and exercise capacity, both the FFP and SPPB had predictive value in relation to mortality (FFP aHR = 1.31 [95% CI 1.03â 1.66]; SPPB aHR = 1.29 [95% CI 0.99â 1.68]).Conclusion: In stable COPD, both the FFP and SPPB identify similar proportions of people living with/without frailty, the majority with matching classifications. Both measures can identify individuals with multidimensional health challenges and increased mortality risk and provide additional information alongside established prognostic variables.Keywords: respiratory disease, chronic obstructive pulmonary disease, frailty, survival
Published: 2023
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16. Phytoplankton and zooplankton abundance and distribution: a case of Ghodaghodi Lake, Sudurpaschim Province, Nepal

Author: Melina DC, Archana Prasad, Smriti Gurung, Rita Bhatta, Dikshya Regmi, Shrija Tuladhar, and Chhatra Mani Sharma
Subjects: Ecology, Insect Science, Ecology, Evolution, Behavior and Systematics
Abstract: Planktons are the community of pelagic organisms, composed of different groups, which are in suspension in water and hence restricted mobility, often less than that of the water which carries them. The study was carried out during the winter of 2019 to observe the phytoplankton and zooplankton abundance and distribution in Ghodaghodi Lake, Nepal. Temperature, pH, electrical conductivity, dissolved oxygen, Secchi disc transparency, total dissolved solids, and turbidity were analyzed during the study. Collection of plankton samples were made by conical-shaped monofilament nylon plankton net of 90 μm mesh net size from approximately 10 ‐ 12 cm depth from six different sites. A total of 58 individuals of zooplankton were enumerated during the present investigation. The maximum number was counted for Mesocyclops sp (n=18) and minimum for Diaptomus (n=1). The highest zooplanktons were reported from site I (n= 12) and the lowest were reported from site II (n=7). Cladocera was the most dominating zooplankton group. A total of 85 individuals of phytoplankton were enumerated during the present investigation. The maximum number was counted for Spirogyra sp (30) and the minimum for Lamena sp (1). The most leading group of the phytoplankton was Chlorophyceae (30), followed by Cyanophyceae (13), Bacillariophyceae (7) and group Zygnematophyceae (6). Thus, these resources are also favorable for flourishing fish diversity in a lake ecosystem.
Published: 2022
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17. Relationship Between Subchorionic Haematoma and Abdominal Massage in Pregnancy in the Niger Delta Region of Nigeria: A Pilot Study

Author: EK Kiridi, PC Oriji, C Okechukwu, DC Briggs, JU Ugwoegbu, AE Ubom, AO Addah, IJ Abasi, PY Bosrotsi, and AD Adesina
Subjects: Materials Chemistry
Abstract: Background: Abdominal massage (AM) in pregnancy is a common practice in the Niger Delta region of Nigeria. AM may cause events such as subchorionic haematoma (SAH) and increase the risk of miscarriages and adverse maternal and perinatal outcomes. Objective: To determine the relationship between AM and SCH in the Niger Delta region of Nigeria. Methods: A cross-sectional study was conducted from January to June 2022 at the Obstetrics and Radiology Units of four health facilities in Bayelsa State, Nigeria. Consenting eligible pregnant women presenting to the antenatal clinic during the first trimester were consecutively included. An obstetric ultrasound scan was performed transabdominal. Results: Of the 403 women recruited, 241 (59.8%) were aged (20 – 29 years). The mean age was 28.02 ± 5.99 years. The mean body mass index was 23.82±4.60 kg/m2. While 170 (42.2%) had undergone AM in the first trimester of the index pregnancy, 126 (31.3%) had vaginal bleeding, and SCH occurred in 109 (27.0%) women. Women who had AM had 210 (CI: 58 – 878) times the odds of having SCH and 3.3 (CI: 2.14 – 5.15) times the odds of vaginal bleeding than women who did not have AM. Only 2 (1.8%) women with SCH did not have AM. Conclusion: There exists a strong association between the occurrence of SCH among pregnant women who have had AM. More health education is needed for women in the Niger Delta region and Nigeria to eradicate the archaic practice and improve pregnancy outcomes.
Published: 2022
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18. Oscar Celestino Croxatto (1911-1980) y su paso por nuestro Hospital

Author: Juan DC Emery
Published: 2022
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19. Measurement of the total cross section and ρ -parameter from elastic scattering in pp collisions at √s=13 TeV with the ATLAS detector

Author: Aad, G, Abbott, B, Abbott, DC, Abeling, K, Abidi, SH, Aboulhorma, A, Abramowicz, H, Abreu, H, Abulaiti, Y, Abusleme Hoffman, AC, Acharya, BS, Achkar, B, Adam Bourdarios, C, Adamczyk, L, Adamek, L, Addepalli, SV, Adelman, J, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agaras, MN, Agarwala, J, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmad, A, Ahmadov, F, Ahmed, WS, Ahuja, S, Ai, X, Aielli, G, Aizenberg, I, Akbiyik, M, Åkesson, TPA, Akimov, AV, Al Khoury, K, Alberghi, GL, Albert, J, Albicocco, P, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Ali, S, Aliev, M, Alimonti, G, Alkakhi, W, Allaire, C, Allbrooke, BMM, Allport, PP, Aloisio, A, Alonso, F, Alpigiani, C, Alunno Camelia, E, Alvarez Estevez, M, Alviggi, MG, Aly, M, Amaral Coutinho, Y, Ambler, A, Amelung, C, Ames, CG, Amidei, D, Amor Dos Santos, SP, Amoroso, S, Amos, KR, Ananiev, V, Anastopoulos, C, Andeen, T, Anders, JK, Andrean, SY, Andreazza, A, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antipov, E, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aoki, T, Aparisi Pozo, JA, Aparo, MA, Aperio Bella, L, Appelt, C, Aranzabal, N, Araujo Ferraz, V, Arcangeletti, C, Arce, ATH, Arena, E, Arguin, JF, Aad, G [0000-0002-6665-4934], Abbott, B [0000-0002-5888-2734], Abbott, DC [0000-0002-7248-3203], Abeling, K [0000-0002-1002-1652], Abidi, SH [0000-0002-8496-9294], Aboulhorma, A [0000-0002-9987-2292], Abramowicz, H [0000-0001-5329-6640], Abreu, H [0000-0002-1599-2896], Abulaiti, Y [0000-0003-0403-3697], Abusleme Hoffman, AC [0000-0003-0762-7204], Acharya, BS [0000-0002-8588-9157], Achkar, B [0000-0002-0288-2567], Adam Bourdarios, C [0000-0002-2634-4958], Adamczyk, L [0000-0002-5859-2075], Adamek, L [0000-0003-1562-3502], Addepalli, SV [0000-0002-2919-6663], Adelman, J [0000-0002-1041-3496], Adiguzel, A [0000-0001-6644-0517], Adorni, S [0000-0003-3620-1149], Adye, T [0000-0003-0627-5059], Affolder, AA [0000-0002-9058-7217], Afik, Y [0000-0001-8102-356X], Agaras, MN [0000-0002-4355-5589], Agarwala, J [0000-0002-4754-7455], Aggarwal, A [0000-0002-1922-2039], Agheorghiesei, C [0000-0003-3695-1847], Aguilar-Saavedra, JA [0000-0002-5475-8920], Ahmad, A [0000-0001-8638-0582], Ahmed, WS [0000-0003-0128-3279], Ahuja, S [0000-0003-4368-9285], Ai, X [0000-0003-3856-2415], Aielli, G [0000-0002-0573-8114], Aizenberg, I [0000-0003-2150-1624], Akbiyik, M [0000-0002-7342-3130], Åkesson, TPA [0000-0003-4141-5408], Akimov, AV [0000-0002-2846-2958], Al Khoury, K [0000-0002-0547-8199], Alberghi, GL [0000-0003-2388-987X], Albert, J [0000-0003-0253-2505], Albicocco, P [0000-0001-6430-1038], Alderweireldt, S [0000-0002-8224-7036], Aleksa, M [0000-0002-1936-9217], Aleksandrov, IN [0000-0001-7381-6762], Alexa, C [0000-0003-0922-7669], Alexopoulos, T [0000-0002-8977-279X], Alfonsi, A [0000-0001-7406-4531], Alfonsi, F [0000-0002-0966-0211], Alhroob, M [0000-0001-7569-7111], Ali, B [0000-0001-8653-5556], Ali, S [0000-0001-5216-3133], Aliev, M [0000-0002-9012-3746], Alimonti, G [0000-0002-7128-9046], Alkakhi, W [0000-0001-9355-4245], Allaire, C [0000-0003-4745-538X], Allbrooke, BMM [0000-0002-5738-2471], Allport, PP [0000-0001-7303-2570], Aloisio, A [0000-0002-3883-6693], Alonso, F [0000-0001-9431-8156], Alpigiani, C [0000-0002-7641-5814], Alvarez Estevez, M [0000-0002-8181-6532], Alviggi, MG [0000-0003-0026-982X], Aly, M [0000-0003-3043-3715], Amaral Coutinho, Y [0000-0002-1798-7230], Ambler, A [0000-0003-2184-3480], Ames, CG [0000-0002-2126-4246], Amidei, D [0000-0002-6814-0355], Amor Dos Santos, SP [0000-0001-7566-6067], Amoroso, S [0000-0001-5450-0447], Amos, KR [0000-0003-1757-5620], Ananiev, V [0000-0003-3649-7621], Anastopoulos, C [0000-0003-1587-5830], Andeen, T [0000-0002-4413-871X], Anders, JK [0000-0002-1846-0262], Andrean, SY [0000-0002-9766-2670], Andreazza, A [0000-0001-5161-5759], Angelidakis, S [0000-0002-8274-6118], Angerami, A [0000-0001-7834-8750], Anisenkov, AV [0000-0002-7201-5936], Annovi, A [0000-0002-4649-4398], Antel, C [0000-0001-9683-0890], Anthony, MT [0000-0002-5270-0143], Antipov, E [0000-0002-6678-7665], Antonelli, M [0000-0002-2293-5726], Antrim, DJA [0000-0001-8084-7786], Anulli, F [0000-0003-2734-130X], Aoki, M [0000-0001-7498-0097], Aoki, T [0000-0002-6618-5170], Aparisi Pozo, JA [0000-0001-7401-4331], Aparo, MA [0000-0003-4675-7810], Aperio Bella, L [0000-0003-3942-1702], Appelt, C [0000-0003-1205-6784], Aranzabal, N [0000-0001-9013-2274], Araujo Ferraz, V [0000-0003-1177-7563], Arcangeletti, C [0000-0001-8648-2896], Arce, ATH [0000-0002-7255-0832], Arena, E [0000-0001-5970-8677], Arguin, JF [0000-0003-0229-3858], and Apollo - University of Cambridge Repository
Subjects: 51 Physical Sciences, 5107 Particle and High Energy Physics
Abstract: In a special run of the LHC with $$\beta ^{\star } = 2.5$$ β ⋆ = 2.5 km, proton–proton elastic-scattering events were recorded at $$\sqrt{s} = 13$$ s = 13 TeV with an integrated luminosity of $$340~\upmu {\text {b}}^{-1}$$ 340 μ b - 1 using the ALFA subdetector of ATLAS in 2016. The elastic cross section was measured differentially in the Mandelstam t variable in the range from $$-t = 2.5 \cdot 10^{-4}$$ - t = 2.5 · 10 - 4 GeV$$^{2}$$ 2 to $$-t = 0.46$$ - t = 0.46 GeV$$^{2}$$ 2 using 6.9 million elastic-scattering candidates. This paper presents measurements of the total cross section $$\sigma _{\text {tot}}$$ σ tot , parameters of the nuclear slope, and the $$\rho $$ ρ -parameter defined as the ratio of the real part to the imaginary part of the elastic-scattering amplitude in the limit $$t \rightarrow 0$$ t → 0 . These parameters are determined from a fit to the differential elastic cross section using the optical theorem and different parameterizations of the t-dependence. The results for $$\sigma _{\text {tot}}$$ σ tot and $$\rho $$ ρ are $$\begin{aligned} \sigma _{\text {tot}}(pp\rightarrow X) = 104.7 \pm 1.1 \; \text{ mb },\quad \rho = 0.098 \pm 0.011 . \end{aligned}$$ σ tot ( p p → X ) = 104.7 ± 1.1 mb , ρ = 0.098 ± 0.011 . The uncertainty in $$\sigma _{\text {tot}}$$ σ tot is dominated by the luminosity measurement, and in $$\rho $$ ρ by imperfect knowledge of the detector alignment and by modelling of the nuclear amplitude.
Published: 2023

20. Measurement of the nuclear modification factor of b-jets in 5.02 TeV Pb+Pb collisions with the ATLAS detector

Author: Aad, G, Abbott, B, Abbott, DC, Abeling, K, Abidi, SH, Aboulhorma, A, Abramowicz, H, Abreu, H, Abulaiti, Y, Hoffman, ACA, Acharya, BS, Achkar, B, Adam, L, Bourdarios, CA, Adamczyk, L, Adamek, L, Addepalli, SV, Adelman, J, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agaras, MN, Agarwala, J, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmad, A, Ahmadov, F, Ahmed, WS, Ai, X, Aielli, G, Aizenberg, I, Akbiyik, M, Åkesson, TPA, Akimov, AV, Khoury, KA, Alberghi, GL, Albert, J, Albicocco, P, Verzini, MJA, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Ali, S, Aliev, M, Alimonti, G, Allaire, C, Allbrooke, BMM, Allport, PP, Aloisio, A, Alonso, F, Alpigiani, C, Camelia, EA, Estevez, MA, Alviggi, MG, Coutinho, YA, Ambler, A, Amelung, C, Ames, CG, Amidei, D, Santos, SPAD, Amoroso, S, Amos, KR, Amrouche, CS, Ananiev, V, Anastopoulos, C, Andari, N, Andeen, T, Anders, JK, Andrean, SY, Andreazza, A, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antipov, E, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Pozo, JAA, Aparo, MA, Bella, LA, Appelt, C, Aranzabal, N, Ferraz, VA, Arcangeletti, C, Arce, ATH, Arena, E, Arguin, JF, Aad, G [0000-0002-6665-4934], Abbott, B [0000-0002-5888-2734], Abbott, DC [0000-0002-7248-3203], Abeling, K [0000-0002-1002-1652], Abidi, SH [0000-0002-8496-9294], Aboulhorma, A [0000-0002-9987-2292], Abramowicz, H [0000-0001-5329-6640], Abreu, H [0000-0002-1599-2896], Abulaiti, Y [0000-0003-0403-3697], Hoffman, ACA [0000-0003-0762-7204], Acharya, BS [0000-0002-8588-9157], Achkar, B [0000-0002-0288-2567], Adam, L [0000-0001-6005-2812], Bourdarios, CA [0000-0002-2634-4958], Adamczyk, L [0000-0002-5859-2075], Adamek, L [0000-0003-1562-3502], Addepalli, SV [0000-0002-2919-6663], Adelman, J [0000-0002-1041-3496], Adiguzel, A [0000-0001-6644-0517], Adorni, S [0000-0003-3620-1149], Adye, T [0000-0003-0627-5059], Affolder, AA [0000-0002-9058-7217], Afik, Y [0000-0001-8102-356X], Agaras, MN [0000-0002-4355-5589], Agarwala, J [0000-0002-4754-7455], Aggarwal, A [0000-0002-1922-2039], Agheorghiesei, C [0000-0003-3695-1847], Aguilar-Saavedra, JA [0000-0002-5475-8920], Ahmad, A [0000-0001-8638-0582], Ahmed, WS [0000-0003-0128-3279], Ai, X [0000-0003-3856-2415], Aielli, G [0000-0002-0573-8114], Aizenberg, I [0000-0003-2150-1624], Akbiyik, M [0000-0002-7342-3130], Åkesson, TPA [0000-0003-4141-5408], Akimov, AV [0000-0002-2846-2958], Khoury, KA [0000-0002-0547-8199], Alberghi, GL [0000-0003-2388-987X], Albert, J [0000-0003-0253-2505], Albicocco, P [0000-0001-6430-1038], Verzini, MJA [0000-0003-2212-7830], Alderweireldt, S [0000-0002-8224-7036], Aleksa, M [0000-0002-1936-9217], Aleksandrov, IN [0000-0001-7381-6762], Alexa, C [0000-0003-0922-7669], Alexopoulos, T [0000-0002-8977-279X], Alfonsi, A [0000-0001-7406-4531], Alfonsi, F [0000-0002-0966-0211], Alhroob, M [0000-0001-7569-7111], Ali, B [0000-0001-8653-5556], Ali, S [0000-0001-5216-3133], Aliev, M [0000-0002-9012-3746], Alimonti, G [0000-0002-7128-9046], Allaire, C [0000-0003-4745-538X], Allbrooke, BMM [0000-0002-5738-2471], Allport, PP [0000-0001-7303-2570], Aloisio, A [0000-0002-3883-6693], Alonso, F [0000-0001-9431-8156], Alpigiani, C [0000-0002-7641-5814], Estevez, MA [0000-0002-8181-6532], Alviggi, MG [0000-0003-0026-982X], Coutinho, YA [0000-0002-1798-7230], Ambler, A [0000-0003-2184-3480], Ames, CG [0000-0002-2126-4246], Amidei, D [0000-0002-6814-0355], Santos, SPAD [0000-0001-7566-6067], Amoroso, S [0000-0001-5450-0447], Amos, KR [0000-0003-1757-5620], Ananiev, V [0000-0003-3649-7621], Anastopoulos, C [0000-0003-1587-5830], Andari, N [0000-0002-4935-4753], Andeen, T [0000-0002-4413-871X], Anders, JK [0000-0002-1846-0262], Andrean, SY [0000-0002-9766-2670], Andreazza, A [0000-0001-5161-5759], Angelidakis, S [0000-0002-8274-6118], Angerami, A [0000-0001-7834-8750], Anisenkov, AV [0000-0002-7201-5936], Annovi, A [0000-0002-4649-4398], Antel, C [0000-0001-9683-0890], Anthony, MT [0000-0002-5270-0143], Antipov, E [0000-0002-6678-7665], Antonelli, M [0000-0002-2293-5726], Antrim, DJA [0000-0001-8084-7786], Anulli, F [0000-0003-2734-130X], Aoki, M [0000-0001-7498-0097], Pozo, JAA [0000-0001-7401-4331], Aparo, MA [0000-0003-4675-7810], Bella, LA [0000-0003-3942-1702], Appelt, C [0000-0003-1205-6784], Aranzabal, N [0000-0001-9013-2274], Ferraz, VA [0000-0003-1177-7563], Arcangeletti, C [0000-0001-8648-2896], Arce, ATH [0000-0002-7255-0832], Arena, E [0000-0001-5970-8677], Arguin, JF [0000-0003-0229-3858], and Apollo - University of Cambridge Repository
Subjects: Pediatric Research Initiative, 51 Physical Sciences, 5107 Particle and High Energy Physics
Abstract: This paper presents a measurement of b-jet production in Pb+Pb and pp collisions at $$\sqrt{s_{_\text {NN}}}=5.02$$ s NN = 5.02 TeV with the ATLAS detector at the LHC. The measurement uses 260 $$\text {pb}^{-1}$$ pb - 1 of pp collisions collected in 2017 and 1.4 $$\text {nb}^{-1}$$ nb - 1 of Pb+Pb collisions collected in 2018. In both collision systems, jets are reconstructed via the anti-$$k_{t}$$ k t algorithm. The b-jets are identified from a sample of jets containing muons from the semileptonic decay of b-quarks using template fits of the muon momentum relative to the jet axis. In pp collisions, b-jets are reconstructed for radius parameters $$R= 0.2$$ R = 0.2 and $$R= 0.4$$ R = 0.4 , and only $$R= 0.2$$ R = 0.2 jets are used in Pb+Pb collisions. For comparison, inclusive $$R= 0.2$$ R = 0.2 jets are also measured using 1.7 $$\text {nb}^{-1}$$ nb - 1 of Pb+Pb collisions collected in 2018 and the same pp collision data as the b-jet measurement. The nuclear modification factor, $$R_\text {AA}$$ R AA , is calculated for both b-jets and inclusive jets with $$R= 0.2$$ R = 0.2 over the transverse momentum range of 80–290 GeV. The nuclear modification factor for b-jets decreases from peripheral to central collisions. The ratio of the b-jet $$R_\text {AA}$$ R AA to inclusive jet $$R_\text {AA}$$ R AA is also presented and suggests that the $$R_\text {AA}$$ R AA for b-jets is larger than that for inclusive jets in central Pb+Pb collisions. The measurements are compared with theoretical calculations and suggest a role for mass and colour-charge effects in partonic energy loss in heavy-ion collisions.
Published: 2023

21. The JWST Early-release Science Program for Direct Observations of Exoplanetary Systems II: A 1 to 20 μm Spectrum of the Planetary-mass Companion VHS 1256-1257 b

Author: Miles, BE, Biller, BA, Patapis, P, Worthen, K, Rickman, E, Hoch, KKW, Skemer, A, Perrin, MD, Whiteford, N, Chen, CH, Sargent, B, Mukherjee, S, Morley, CV, Moran, SE, Bonnefoy, M, Petrus, S, Carter, AL, Choquet, E, Hinkley, S, Ward-Duong, K, Leisenring, JM, Millar-Blanchaer, MA, Pueyo, L, Ray, S, Sallum, S, Stapelfeldt, KR, Stone, JM, Wang, JJ, Absil, O, Balmer, WO, Boccaletti, A, Bonavita, M, Booth, M, Bowler, BP, Chauvin, G, Christiaens, V, Currie, T, Danielski, C, Fortney, JJ, Girard, JH, Grady, CA, Greenbaum, AZ, Henning, T, Hines, DC, Janson, M, Kalas, P, Kammerer, J, Kennedy, GM, Kenworthy, MA, Kervella, P, Lagage, PO, Lew, BWP, Liu, MC, Macintosh, B, Marino, S, Marley, MS, Marois, C, Matthews, EC, Matthews, BC, Mawet, D, McElwain, MW, Metchev, S, Meyer, MR, Molliere, P, Pantin, E, Quirrenbach, A, Rebollido, I, Ren, BB, Schneider, G, Vasist, M, Wyatt, MC, Zhou, Y, Briesemeister, ZW, Bryan, ML, Calissendorff, P, Cantalloube, F, Cugno, G, De Furio, M, Dupuy, TJ, Factor, SM, Faherty, JK, Fitzgerald, MP, Franson, K, Gonzales, EC, Hood, CE, Howe, AR, Kraus, AL, Kuzuhara, M, Lagrange, AM, Lawson, K, Lazzoni, C, Liu, P, Llop-Sayson, J, Lloyd, JP, Martinez, RA, Mazoyer, J, Quanz, SP, Redai, JA, Samland, M, Schlieder, JE, Miles, BE [0000-0002-5500-4602], Biller, BA [0000-0003-4614-7035], Patapis, P [0000-0001-8718-3732], Worthen, K [0000-0002-5885-5779], Rickman, E [0000-0003-4203-9715], Hoch, KKW [0000-0002-9803-8255], Skemer, A [0000-0001-6098-3924], Perrin, MD [0000-0002-3191-8151], Whiteford, N [0000-0001-8818-1544], Chen, CH [0000-0002-8382-0447], Sargent, B [0000-0001-9855-8261], Mukherjee, S [0000-0003-1622-1302], Morley, CV [0000-0002-4404-0456], Moran, SE [0000-0002-6721-3284], Bonnefoy, M [0000-0001-5579-5339], Petrus, S [0000-0003-0331-3654], Carter, AL [0000-0001-5365-4815], Choquet, E [0000-0002-9173-0740], Hinkley, S [0000-0001-8074-2562], Ward-Duong, K [0000-0002-4479-8291], Leisenring, JM [0000-0002-0834-6140], Millar-Blanchaer, MA [0000-0001-6205-9233], Ray, S [0000-0003-2259-3911], Sallum, S [0000-0001-6871-6775], Stapelfeldt, KR [0000-0002-2805-7338], Stone, JM [0000-0003-0454-3718], Wang, JJ [0000-0003-0774-6502], Absil, O [0000-0002-4006-6237], Balmer, WO [0000-0001-6396-8439], Boccaletti, A [0000-0001-9353-2724], Bonavita, M [0000-0002-7520-8389], Booth, M [0000-0001-8568-6336], Bowler, BP [0000-0003-2649-2288], Chauvin, G [0000-0003-4022-8598], Christiaens, V [0000-0002-0101-8814], Currie, T [0000-0002-7405-3119], Danielski, C [0000-0002-3729-2663], Fortney, JJ [0000-0002-9843-4354], Girard, JH [0000-0001-8627-0404], Greenbaum, AZ [0000-0002-7162-8036], Henning, T [0000-0002-1493-300X], Hines, DC [0000-0003-4653-6161], Janson, M [0000-0001-8345-593X], Kalas, P [0000-0002-6221-5360], Kammerer, J [0000-0003-2769-0438], Kennedy, GM [0000-0001-6831-7547], Kenworthy, MA [0000-0002-7064-8270], Kervella, P [0000-0003-0626-1749], Lew, BWP [0000-0003-1487-6452], Liu, MC [0000-0003-2232-7664], Macintosh, B [0000-0003-1212-7538], Marino, S [0000-0002-5352-2924], Marley, MS [0000-0002-5251-2943], Marois, C [0000-0002-4164-4182], Matthews, EC [0000-0003-0593-1560], Matthews, BC [0000-0003-3017-9577], Mawet, D [0000-0002-8895-4735], McElwain, MW [0000-0003-0241-8956], Metchev, S [0000-0003-3050-8203], Meyer, MR [0000-0003-1227-3084], Molliere, P [0000-0003-4096-7067], Pantin, E [0000-0001-6472-2844], Rebollido, I [0000-0002-4388-6417], Ren, BB [0000-0003-1698-9696], Schneider, G [0000-0002-4511-5966], Vasist, M [0000-0002-4511-3602], Wyatt, MC [0000-0001-9064-5598], Zhou, Y [0000-0003-2969-6040], Briesemeister, ZW [0000-0002-1764-2494], Bryan, ML [0000-0002-6076-5967], Calissendorff, P [0000-0002-5335-0616], Cantalloube, F [0000-0002-3968-3780], Cugno, G [0000-0001-7255-3251], De Furio, M [0000-0003-1863-4960], Dupuy, TJ [0000-0001-9823-1445], Factor, SM [0000-0002-8332-8516], Faherty, JK [0000-0001-6251-0573], Fitzgerald, MP [0000-0002-0176-8973], Franson, K [0000-0003-4557-414X], Gonzales, EC [0000-0003-4636-6676], Hood, CE [0000-0003-1150-7889], Howe, AR [0000-0002-4884-7150], Kraus, AL [0000-0001-9811-568X], Kuzuhara, M [0000-0002-4677-9182], Lawson, K [0000-0002-6964-8732], Lazzoni, C [0000-0001-7819-9003], Liu, P [0000-0001-7047-0874], Llop-Sayson, J [0000-0002-3414-784X], Martinez, RA [0000-0001-6301-896X], Mazoyer, J [0000-0002-9133-3091], Quanz, SP [0000-0003-3829-7412], Redai, JA [0000-0002-4489-3168], Samland, M [0000-0001-9992-4067], Schlieder, JE [0000-0001-5347-7062], and Apollo - University of Cambridge Repository
Subjects: The Solar System, Exoplanets, and Astrobiology, 5109 Space Sciences, 51 Physical Sciences
Abstract: We present the highest fidelity spectrum to date of a planetary-mass object. VHS 1256 b is a M Jup widely separated (∼8″, a = 150 au), young, planetary-mass companion that shares photometric colors and spectroscopic features with the directly imaged exoplanets HR 8799c, d, and e. As an L-to-T transition object, VHS 1256 b exists along the region of the color–magnitude diagram where substellar atmospheres transition from cloudy to clear. We observed VHS 1256 b with JWST's NIRSpec IFU and MIRI MRS modes for coverage from 1 to 20 μm at resolutions of ∼1000–3700. Water, methane, carbon monoxide, carbon dioxide, sodium, and potassium are observed in several portions of the JWST spectrum based on comparisons from template brown dwarf spectra, molecular opacities, and atmospheric models. The spectral shape of VHS 1256 b is influenced by disequilibrium chemistry and clouds. We directly detect silicate clouds, the first such detection reported for a planetary-mass companion.
Published: 2023

22. Preparation and characterization of antibacterial gels of galactomannan/ZnO nanocomposite in carbopol-based matrix using mesquite seeds as the biopolymer source

Author: DC Bouttier-Figueroa, JA García-Valenzuela, M Cota-Leal, RE Robles-Zepeda, and M Sotelo-Lerma
Subjects: Polymers and Plastics
Abstract: Nanocomposite gels are novel materials mainly used in the medical field for the control drug release and distribution. In this study, the effect of the concentration of galactomannan/zinc oxide nanocomposite in a polymeric Carbopol matrix to obtain a functional nanocomposite gel was studied. The swelling, thermogravimetric, rheological, and antibacterial properties against Escherichia coli and Staphylococcus aureus were evaluated. The results indicate that there is a direct effect between the amount of the employed nanocomposite and the properties studied in the gels. In this regard, we present a formulation that demonstrates that the prepared nanocomposite gel has ideal properties to be used in the medical field as an antibacterial agent.
Published: 2022
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23. Improved Constraints on the 21 cm EoR Power Spectrum and the X-Ray Heating of the IGM with HERA Phase I Observations

Author: Abdurashidova, THCZ, Adams, T, Aguirre, JE, Alexander, P, Ali, ZS, Baartman, R, Balfour, Y, Barkana, R, Beardsley, AP, Bernardi, G, Billings, TS, Bowman, JD, Bradley, RF, Breitman, D, Bull, P, Burba, J, Carey, S, Carilli, CL, Cheng, C, Choudhuri, S, DeBoer, DR, De Lera Acedo, E, Dexter, M, Dillon, JS, Ely, J, Ewall-Wice, A, Fagnoni, N, Fialkov, A, Fritz, R, Furlanetto, Gale-Sides, K, Garsden, H, Glendenning, B, Gorce, A, Gorthi, D, Greig, B, Grobbelaar, J, Halday, Z, Hazelton, BJ, Heimersheim, S, Hewitt, JN, Hickish, J, Jacobs, DC, Julius, A, Kern, NS, Kerrigan, J, Kittiwisit, P, Kohn, SA, Kolopanis, M, Lanman, A, La Plante, P, Lewis, D, Liu, A, Loots, A, Ma, YZ, MacMahon, DHE, Malan, L, Malgas, K, Malgas, C, Maree, M, Marero, B, Martinot, ZE, McBride, L, Mesinger, A, Mirocha, J, Molewa, M, Morales, MF, Mosiane, T, Muñoz, JB, Murray, SG, Nagpal, V, Neben, AR, Nikolic, B, Nunhokee, CD, Nuwegeld, H, Parsons, AR, Pascua, R, Patra, N, Pieterse, S, Qin, Y, Razavi-Ghods, N, Robnett, J, Rosie, K, Santos, MG, Sims, P, Singh, S, Smith, C, Swarts, H, Tan, J, Thyagarajan, N, Wilensky, MJ, Williams, PKG, Van Wyngaarden, P, Zheng, H, Aguirre, JE [0000-0002-4810-666X], Barkana, R [0000-0002-1557-693X], Beardsley, AP [0000-0001-9428-8233], Bernardi, G [0000-0002-0916-7443], Bowman, JD [0000-0002-8475-2036], Bradley, RF [0000-0003-1172-8331], Breitman, D [0000-0002-2349-3341], Bull, P [0000-0001-5668-3101], Carilli, CL [0000-0001-6647-3861], Choudhuri, S [0000-0002-2338-935X], DeBoer, DR [0000-0003-3197-2294], de Lera Acedo, E [0000-0001-8530-6989], Dillon, JS [0000-0003-3336-9958], Ewall-Wice, A [0000-0002-0086-7363], Fagnoni, N [0000-0001-5300-3166], Fialkov, A [0000-0002-1369-633X], Furlanetto, SR [0000-0002-0658-1243], Gorce, A [0000-0002-1712-737X], Gorthi, D [0000-0002-0829-167X], Greig, B [0000-0002-4085-2094], Hazelton, BJ [0000-0001-7532-645X], Heimersheim, S [0000-0001-9631-4212], Hewitt, JN [0000-0002-4117-570X], Jacobs, DC [0000-0002-0917-2269], Kern, NS [0000-0002-8211-1892], Kerrigan, J [0000-0002-1876-272X], Kittiwisit, P [0000-0003-0953-313X], Kohn, SA [0000-0001-6744-5328], Kolopanis, M [0000-0002-2950-2974], Lanman, A [0000-0003-2116-3573], La Plante, P [0000-0002-4693-0102], Liu, A [0000-0001-6876-0928], Ma, YZ [0000-0001-8108-0986], Mesinger, A [0000-0003-3374-1772], Mirocha, J [0000-0002-8802-5581], Morales, MF [0000-0001-7694-4030], Muñoz, JB [0000-0002-8984-0465], Murray, SG [0000-0003-3059-3823], Nagpal, V [0000-0001-5909-4433], Neben, AR [0000-0001-7776-7240], Nikolic, B [0000-0001-7168-2705], Nunhokee, CD [0000-0002-5445-6586], Parsons, AR [0000-0002-5400-8097], Pascua, R [0000-0003-0073-5528], Patra, N [0000-0002-9457-1941], Qin, Y [0000-0002-4314-1810], Razavi-Ghods, N [0000-0003-2930-5396], Rosie, K [0000-0003-3611-8804], Santos, MG [0000-0003-3892-3073], Sims, P [0000-0002-2871-0413], Singh, S [0000-0001-7755-902X], Tan, J [0000-0001-6161-7037], Thyagarajan, N [0000-0003-1602-7868], Wilensky, MJ [0000-0001-7716-9312], Williams, PKG [0000-0003-3734-3587], Zheng, H [0000-0001-8267-3425], and Apollo - University of Cambridge Repository
Subjects: Space and Planetary Science, 5101 Astronomical Sciences, Astronomy and Astrophysics, 51 Physical Sciences
Abstract: We report the most sensitive upper limits to date on the 21 cm epoch of reionization power spectrum using 94 nights of observing with Phase I of the Hydrogen Epoch of Reionization Array (HERA). Using similar analysis techniques as in previously reported limits, we find at 95% confidence that Δ2(k = 0.34 h Mpc−1) ≤ 457 mK2 at z = 7.9 and that Δ2(k = 0.36 h Mpc−1) ≤ 3496 mK2 at z = 10.4, an improvement by a factor of 2.1 and 2.6, respectively. These limits are mostly consistent with thermal noise over a wide range of k after our data quality cuts, despite performing a relatively conservative analysis designed to minimize signal loss. Our results are validated with both statistical tests on the data and end-to-end pipeline simulations. We also report updated constraints on the astrophysics of reionization and the cosmic dawn. Using multiple independent modeling and inference techniques previously employed by HERA Collaboration, we find that the intergalactic medium must have been heated above the adiabatic cooling limit at least as early as z = 10.4, ruling out a broad set of so-called “cold reionization” scenarios. If this heating is due to high-mass X-ray binaries during the cosmic dawn, as is generally believed, our result’s 99% credible interval excludes the local relationship between soft X-ray luminosity and star formation and thus requires heating driven by evolved low-metallicity stars.
Published: 2023

24. Measurement of angular and momentum distributions of charged particles within and around jets in Pb+Pb and pp collisions at sNN=5.02 TeV with the ATLAS detector

Author: Aad, G, Abbott, B, Abbott, DC, Abed Abud, A, Abeling, K, Abhayasinghe, DK, Abidi, SH, AbouZeid, OS, Abraham, NL, Abramowicz, H, Abreu, H, Abulaiti, Y, Acharya, BS, Achkar, B, Adachi, S, Adam, L, Adam Bourdarios, C, Adamczyk, L, Adamek, L, Adelman, J, Adersberger, M, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agapopoulou, C, Agaras, MN, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmadov, F, Ahmed, WS, Ai, X, Aielli, G, Akatsuka, S, Åkesson, TPA, Akilli, E, Akimov, AV, Al Khoury, K, Alberghi, GL, Albert, J, Alconada Verzini, MJ, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexandre, D, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Alimonti, G, Alison, J, Alkire, SP, Allaire, C, Allbrooke, BMM, Allen, BW, Allport, PP, Aloisio, A, Alonso, A, Alonso, F, Alpigiani, C, Alshehri, AA, Alvarez Estevez, M, Álvarez Piqueras, D, Alviggi, MG, Amaral Coutinho, Y, Ambler, A, Ambroz, L, Amelung, C, Amidei, D, Amor Dos Santos, SP, Amoroso, S, Amrouche, CS, An, F, Anastopoulos, C, Andari, N, Andeen, T, Anders, CF, Anders, JK, Andreazza, A, Andrei, V, Anelli, CR, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aparisi Pozo, JA, Aperio Bella, L, Arabidze, G, Araque, JP, and Araujo Ferraz, V
Subjects: Particle and Plasma Physics, Molecular, Nuclear, Atomic, Nuclear & Particles Physics
Published: 2023

25. THE CULTURE OF DIGITAL ACADEMIC COMMISSIONS: AN EXPLORATORY RESEARCH

Author: COS, FRANCISCO JR. DC., DIOKNO, JONATHAN P., RESPITO, LOIS RUTH R., ESTERON, HOMMY LAURENCE D., and GONZALES, CHARMAINE J.
Subjects: Education, Academic Services, Covert Observation, Philippines
Abstract: Academic integrity is one of the transmitted values in the education process. However, due to the impact of unstoppable growing technology, accompanied by the effect of the COVID-19 pandemic to education processes, digital paid academic services became popular among students. This study aimed to explore the culture of paid digital academic services using the principles of covert observation utilizing the cyberethnographic design of qualitative research. The culture of paid academic services in Facebook groups was subjected to this study by analyzing the posts in the group pages. The observations are the following: (1) Academic servants are from different spectrums of educational qualifications, (2) services offered vary, (3) requests of potential clients are (a) to prepare common school requirements, (b) proxy to quizzes or performance tasks, (c) partial or full aids to their thesis, and (d) some notable observations. It was also observed that there are scamming schemes in the group. In the digital era, it is difficult to control paid academic services. Thus, ethically acceptable paid academic services must be clearly defined. Teachers and school administrators are advised to devise a policy for their classes/schools relative to pressing concerns of paid digital academic services. &nbsp
Published: 2023
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26. Delphinium yui M. Idrees & Z. Y. Zhang 2023, nom. nov

Author: Zhang, Zhiyong, Idrees, Muhammad, and Dc, D.
Subjects: Tracheophyta, Magnoliopsida, Ranunculales, Delphinium yui, Biodiversity, Delphinium, Plantae, Ranunculaceae, Taxonomy
Abstract: Delphinium yui M. Idrees & Z.Y. Zhang, nom. nov. Replaced name:— Delphinium omeiense W.T. Wang (1979b: 613) var. pubescens W.T. Wang (1979b: 614). Delphinium pubescens (W.T.Wang) W.T.Wang (2020: 137), nom. illeg., non Delphinium pubescens DC. (1805: 641). Type:— CHINA. Sichuan: Muli Country, Woosi, margins of the woods near stream, alt. 2600 m, 19 Aug. 1937 T.T. Yü 14022 (holotype PE-00934974!, isotypes A00109013!, PE-00934975!). Etymology:—The specific epithet “ yui ” is name after Tse-Tsun Yü who collected the type specimen., Published as part of Zhang, Zhiyong, Idrees, Muhammad & Dc, D., 2023, Delphinium yui, a new replacement name for D. pubescens (Ranunculaceae), pp. 217-218 in Phytotaxa 600 (3) on page 217, DOI: 10.11646/phytotaxa.600.3.8, http://zenodo.org/record/8080897, {"references":["462. Wang, W. T. (1979 b) Addenda. In: Anonymous (Ed.) Flora Reipublicae Popularis Sinicae, vol. 27. Science Press, Beijing, pp. 603 - 621. Wang, W. T. & Warnock, M. J. (2001) Delphinium Linnaeus. In: Wu, Z. Y. & Raven, P. H. (eds.) Flora of China, vol. 6 (Caryophyllaceae through Lardizabalaceae). Science Press, Beijing & Missouri Botanical Garden Press, St. Louis, pp. 223 - 274. Wang, W. T. (2020) A revision of the genus Delphinium (Ranunculaceae) of China (II). Guihaia 20 (Suppl.): 1 - 254. Xie, L. (2016) Delphinium L. In: Wei, F. N. (Ed.) Medical Flora of China, vol. 3. Peking University Medical Press, Beijing, pp. 167 - 205. Yin, T., Cai, L. & Ding, Z. (2020) An overview of the chemical constituents from the genus Delphinium reported in the last four decades."]}
Published: 2023
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27. Delphinium yui, a new replacement name for D. pubescens (Ranunculaceae)

Author: Zhang, Zhiyong, Idrees, Muhammad, and Dc, D.
Subjects: Tracheophyta, Magnoliopsida, Ranunculales, Biodiversity, Plantae, Ranunculaceae, Taxonomy
Abstract: Zhang, Zhiyong, Idrees, Muhammad, Dc, D. (2023): Delphinium yui, a new replacement name for D. pubescens (Ranunculaceae). Phytotaxa 600 (3): 217-218, DOI: 10.11646/phytotaxa.600.3.8, URL: http://dx.doi.org/10.11646/phytotaxa.600.3.8
Published: 2023

28. Turmeric Massage Essential Oil Production for Business

Author: GERALDINE DC. CAWAGAS
Abstract: This study discovered that a variety of medical conditions can be managed or overall health can be improved with massage therapy using the product name Curcuma Longa - Turmeric Massage Essential Oil. This study's findings suggest that it may be helpful for fatigue, body pain, and muscle pain. This study used a descriptive survey method that involved survey questionnaires and an informal interview with the respondents. The study's findings show that this product is affordable, suitable for use as massage oil, and effective in the management of muscle discomfort issues. It may also present excellent business and revenue prospects. &nbsp
Published: 2023
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29. A search for new resonances in multiple final states with a high transverse momentum Z boson in √s = 13 TeV pp collisions with the ATLAS detector

Author: Aad, G, Abbott, B, Abbott, DC, Abeling, K, Abidi, SH, Aboulhorma, A, Abramowicz, H, Abreu, H, Abulaiti, Y, Abusleme Hoffman, AC, Acharya, BS, Achkar, B, Adam Bourdarios, C, Adamczyk, L, Adamek, L, Addepalli, SV, Adelman, J, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agaras, MN, Agarwala, J, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmad, A, Ahmadov, F, Ahmed, WS, Ahuja, S, Ai, X, Aielli, G, Aizenberg, I, Akbiyik, M, Åkesson, TPA, Akimov, AV, Al Khoury, K, Alberghi, GL, Albert, J, Albicocco, P, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Ali, S, Aliev, M, Alimonti, G, Alkakhi, W, Allaire, C, Allbrooke, BMM, Allport, PP, Aloisio, A, Alonso, F, Alpigiani, C, Alunno Camelia, E, Alvarez Estevez, M, Alviggi, MG, Aly, M, Amaral Coutinho, Y, Ambler, A, Amelung, C, Amerl, M, Ames, CG, Amidei, D, Amor Dos Santos, SP, Amoroso, S, Amos, KR, Ananiev, V, Anastopoulos, C, Andeen, T, Anders, JK, Andrean, SY, Andreazza, A, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antipov, E, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aoki, T, Aparisi Pozo, JA, Aparo, MA, Aperio Bella, L, Appelt, C, Aranzabal, N, Araujo Ferraz, V, Arcangeletti, C, Arce, ATH, Arena, E, and Apollo - University of Cambridge Repository
Subjects: 5106 Nuclear and Plasma Physics, 51 Physical Sciences, 5107 Particle and High Energy Physics
Abstract: A generic search for resonances is performed with events containing a Z boson with transverse momentum greater than 100 GeV, decaying into e+e− or μ+μ−. The analysed data collected with the ATLAS detector in proton-proton collisions at a centre-of-mass energy of 13 TeV at the Large Hadron Collider correspond to an integrated luminosity of 139 fb−1. Two invariant mass distributions are examined for a localised excess relative to the expected Standard Model background in six independent event categories (and their inclusive sum) to increase the sensitivity. No significant excess is observed. Exclusion limits at 95% confidence level are derived for two cases: a model-independent interpretation of Gaussian-shaped resonances with the mass width between 3% and 10% of the resonance mass, and a specific heavy vector triplet model with the decay mode W′ → ZW →ℓℓqq.
Published: 2023

30. Measurement of the top-quark mass using a leptonic invariant mass in pp collisions at √s = 13 TeV with the ATLAS detector

Author: Aad, G, Abbott, B, Abbott, DC, Abed Abud, A, Abeling, K, Abhayasinghe, DK, Abidi, SH, AbouZeid, OS, Abraham, NL, Abramowicz, H, Abreu, H, Abulaiti, Y, Acharya, BS, Achkar, B, Adachi, S, Adam, L, Adam Bourdarios, C, Adamczyk, L, Adamek, L, Adelman, J, Adersberger, M, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agapopoulou, C, Agaras, MN, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmadov, F, Ahmed, WS, Ai, X, Aielli, G, Akatsuka, S, Åkesson, TPA, Akilli, E, Akimov, AV, Al Khoury, K, Alberghi, GL, Albert, J, Alconada Verzini, MJ, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Aliev, M, Alimonti, G, Allaire, C, Allbrooke, BMM, Allen, BW, Allport, PP, Aloisio, A, Alonso, F, Alpigiani, C, Alshehri, AA, Alunno Camelia, E, Alvarez Estevez, M, Alviggi, MG, Amaral Coutinho, Y, Ambler, A, Ambroz, L, Amelung, C, Amidei, D, Amor Dos Santos, SP, Amoroso, S, Amrouche, CS, An, F, Anastopoulos, C, Andari, N, Andeen, T, Anders, CF, Anders, JK, Andreazza, A, Andrei, V, Anelli, CR, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antipov, E, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aparisi Pozo, JA, Aperio Bella, L, Araque, JP, Araujo Ferraz, V, Araujo Pereira, R, Arcangeletti, C, Arce, ATH, and Apollo - University of Cambridge Repository
Subjects: 4902 Mathematical Physics, 49 Mathematical Sciences, 5106 Nuclear and Plasma Physics, 51 Physical Sciences, 5107 Particle and High Energy Physics
Abstract: A measurement of the top-quark mass (mt) in the $$ t\overline{t} $$ t t ¯ → lepton + jets channel is presented, with an experimental technique which exploits semileptonic decays of b-hadrons produced in the top-quark decay chain. The distribution of the invariant mass mℓμ of the lepton, ℓ (with ℓ = e, μ), from the W-boson decay and the muon, μ, originating from the b-hadron decay is reconstructed, and a binned-template profile likelihood fit is performed to extract mt. The measurement is based on data corresponding to an integrated luminosity of 36.1 fb−1 of $$ \sqrt{s} $$ s = 13 TeV pp collisions provided by the Large Hadron Collider and recorded by the ATLAS detector. The measured value of the top-quark mass is mt = 174.41 ± 0.39 (stat.) ± 0.66 (syst.) ± 0.25 (recoil) GeV, where the third uncertainty arises from changing the Pythia8 parton shower gluon-recoil scheme, used in top-quark decays, to a recently developed setup.
Published: 2023

31. Search for heavy resonances decaying into a Z or W boson and a Higgs boson in final states with leptons and b-jets in 139 fb−1 of pp collisions at √s = 13 TeV with the ATLAS detector

Author: Aad, G, Abbott, B, Abbott, DC, Abeling, K, Abidi, SH, Aboulhorma, A, Abramowicz, H, Abreu, H, Abulaiti, Y, Abusleme Hoffman, AC, Acharya, BS, Achkar, B, Adam, L, Adam Bourdarios, C, Adamczyk, L, Adamek, L, Addepalli, SV, Adelman, J, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agaras, MN, Agarwala, J, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmad, A, Ahmadov, F, Ahmed, WS, Ahuja, S, Ai, X, Aielli, G, Aizenberg, I, Akbiyik, M, Åkesson, TPA, Akimov, AV, Al Khoury, K, Alberghi, GL, Albert, J, Albicocco, P, Alconada Verzini, MJ, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Ali, S, Aliev, M, Alimonti, G, Allaire, C, Allbrooke, BMM, Allport, PP, Aloisio, A, Alonso, F, Alpigiani, C, Alunno Camelia, E, Alvarez Estevez, M, Alviggi, MG, Amaral Coutinho, Y, Ambler, A, Amelung, C, Ames, CG, Amidei, D, Amor Dos Santos, SP, Amoroso, S, Amos, KR, Amrouche, CS, Ananiev, V, Anastopoulos, C, Andari, N, Andeen, T, Anders, JK, Andrean, SY, Andreazza, A, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antipov, E, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aoki, T, Aparisi Pozo, JA, Aparo, MA, Aperio Bella, L, Appelt, C, Aranzabal, N, Araujo Ferraz, V, Arcangeletti, C, Arce, ATH, and Apollo - University of Cambridge Repository
Subjects: 4902 Mathematical Physics, 49 Mathematical Sciences, 51 Physical Sciences, 5107 Particle and High Energy Physics
Abstract: This article presents a search for new resonances decaying into a Z or W boson and a 125 GeV Higgs boson h, and it targets the $$ \nu \overline{\nu}b\overline{b} $$ ν ν ¯ b b ¯ , $$ {\ell}^{+}{\ell}^{-}b\overline{b} $$ ℓ + ℓ − b b ¯ , or $$ {\ell}^{\pm}\nu b\overline{b} $$ ℓ ± νb b ¯ final states, where ℓ = e or μ, in proton-proton collisions at $$ \sqrt{s} $$ s = 13 TeV. The data used correspond to a total integrated luminosity of 139 fb−1 collected by the ATLAS detector during Run 2 of the LHC at CERN. The search is conducted by examining the reconstructed invariant or transverse mass distributions of Zh or Wh candidates for evidence of a localised excess in the mass range from 220 GeV to 5 TeV. No significant excess is observed and 95% confidence-level upper limits between 1.3 pb and 0.3 fb are placed on the production cross section times branching fraction of neutral and charged spin-1 resonances and CP-odd scalar bosons. These limits are converted into constraints on the parameter space of the Heavy Vector Triplet model and the two-Higgs-doublet model.
Published: 2023

32. MEWUJUDKAN KEMANDIRIAN EKONOMI MELALUI PEMBERDAYAAN IBU RUMAH TANGGA DENGAN KETRAMPILAN PEMBUATAN SABUN CUCI PIRING DAN MENGHITUNG HPP

Author: null W Nurhidayati, null Rahoyo, null DC Kuswardhani, and null Nunik Kusnilawati
Abstract: The purpose of this community service activity is to empower women in the Purwoyoso village. This empowerment is able to improve the economic condition of the family. through innovative activities, enabling them to learn various skills to help increase income for women in Purwoyoso sub-district, The method used in this community service activity is to provide direct training with tutorials in the field by teaching making dish soap and calculating HPP (Cost of Production). The results of the service are expected that mothers have skills in making dish soap and calculating HPP so that they can determine the price of goods when sold. With skills in making dish soap, mothers can produce which can later be used alone or sold so that additional income can be obtained.
Published: 2022
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33. Practices of Teachers and Parents of Learners with Special Educational Needs During Pandemic

Author: Janna Marie L. Rosales, Rosein A. Ancheta Jr., Rebecca Dc. Manalastas, Cecilia Elena P. De Los Reyes, Jonathan O. Etcuban, Niña Rozanne T. De Los Reyes, Reylan G. Capuno, Ramil P. Manguilimotan, and Lilibeth C. Pinili
Subjects: General Engineering, Energy Engineering and Power Technology
Abstract: The research focused on the practices of teachers and parents of learners with special educational needs during pandemic employing descriptive-correlational research design. It specifically sought the demographic profile of the teachers and parent-respondents. Using purposive sampling, the respondents of the study consisted of 22 teachers and 26 parents from Academia De Santiago of Tarlac, and Angel Beats Play and Development Center, Manila, Philippines. The frequency count, percentage weighted mean, and correlation analysis were used to treat the data gathered from the survey-questionnaire. Results revealed that that the teacher-respondents “greatly encountered” behavioral problems and “encountered” cognitive development problems in handling LSENs; parent-respondents “encountered” both behavioral and cognitive development problems. There was a “great extent” of practices of teachers while “little extent” in parents’ practices. There was a significant relationship between the demographic profile of the teacher-respondents and the extent of teachers’ practices. Based from the significant findings drawn, this study recommends to upskill teachers’ competencies in handling learners with special education needs. Finally, implementation of the action plan is hereby recommended to improve the behavioral and cognitive aspects of the learners and to further improve practices of teachers and parents of the home-schooled learners with special educational needs during a pandemic and its aftermath.
Published: 2022
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34. Cyanobacterial blooms alter benthic community structure and parasite prevalence among invertebrates in Florida Bay, USA

Author: E Duermit-Moreau, J Bojko, and DC Behringer
Subjects: Ecology, Aquatic Science, Ecology, Evolution, Behavior and Systematics
Abstract: Many marine habitats are at risk due to increasing frequency, intensity, and persistence of harmful algal blooms. Repeated cyanobacterial harmful algal blooms (cyanoHABs) in Florida Bay, USA, kill sponges, resulting in reduced filtration and loss of shelter for benthic species. The loss of these key ecosystem functions can impact disease dynamics if fewer pathogens are filtered from the water column (dilution), if shelter loss increases host density in remaining shelters and a directly transmitted disease is present (host regulation), or if shelter loss changes species distributions and foraging patterns (trophic exposure). We show persistent impacts to hard-bottom communities relative to non-impacted communities 2 yr after a significant cyanoHAB. We compared benthic structure, invertebrate epibenthic/infaunal community composition, and parasitism among macroinvertebrates, stone crab Menippe mercenaria, and Caribbean spiny lobster Panulirus argus. On sites degraded by cyanoHABs, we found more, smaller sponges, indicating regrowth. Despite this evidence of recovery, epibenthic/infaunal invertebrate communities were distinct and more diverse on unimpacted sites. Additionally, there were fewer, smaller bivalves on impacted sites. The bivalve Tucetona pectinata, prey for stone crabs, was nearly absent on impacted sites, resulting in decreased prevalence of the apicomplexan gregarine Nematopsis sp., which is trophically transmitted from T. pectinata to M. mercenaria. Panulirus argus virus 1 also appears to be affected by cyanoHABs, as it was absent on impacted sites but present in 26.5% of spiny lobster on unimpacted sites. Impacts remain evident 2 yr after significant cyanoHABs, which does not bode well for these areas considering the frequent reoccurrence of blooms.
Published: 2022
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35. Niosomal entrapment improved the bactericidal properties of azithromycin against methicillin-resistant Staphylococcus aureus

Author: Gerard Q De Guzman, Celina Daia DG Yap, Angela Perpetua DC Munarriz, Agnes DG Dimaano, and Liza Marie C De Guzman
Subjects: Pharmaceutical Science
Abstract: Aim: This study seeks to optimize niosomal formulations of azithromycin (AZ) and evaluate their activities against methicillin-resistant Staphylococcus aureus (MRSA). Methods: The thin-film hydration was used to prepare niosomes containing various molar ratios of span 60, cholesterol, dicetylphosphate and AZ. Formulation 5, with 5:1:1:1 molar ratio, was optimized based on entrapment efficiency. Solid state analyses and accelerated stability were carried out. The antibacterial properties against MRSA was determined by agar well diffusion method. Results: Physico-chemical characterization of formulation 5 confirmed successful encapsulation of AZ with slightly improved stability at 30°C for 6 months. Niosomal AZ at 0.1% is as effective as vancomycin in inhibiting the growth of MRSA. Conclusion: The antibacterial activities of AZ against MRSA is enhanced when encapsulated within niosomes.
Published: 2022
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36. Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Author: Evans, RA, Leavy, OC, Richardson, M, Elneima, O, McCauley, HJC, Shikotra, A, Singapuri, A, Sereno, M, Saunders, RM, Harris, VC, Houchen-Wolloff, L, Aul, R, Beirne, P, Bolton, CE, Brown, JS, Choudhury, G, Diar-Bakerly, N, Easom, N, Echevarria, C, Fuld, J, Hart, N, Hurst, J, Jones, MG, Parekh, D, Pfeffer, P, Rahman, NM, Rowland-Jones, SL, Shah, AM, Wootton, DG, Chalder, T, Davies, MJ, De Soyza, A, Geddes, JR, Greenhalf, W, Greening, NJ, Heaney, LG, Heller, S, Howard, LS, Jacob, J, Jenkins, RG, Lord, JM, Man, WD-C, McCann, GP, Neubauer, S, Openshaw, PJM, Porter, JC, Rowland, MJ, Scott, JT, Semple, MG, Singh, SJ, Thomas, DC, Toshner, M, Lewis, KE, Thwaites, RS, Briggs, A, Docherty, AB, Kerr, S, Lone, NI, Quint, J, Sheikh, A, Thorpe, M, Zheng, B, Chalmers, JD, Ho, LP, Horsley, A, Marks, M, Poinasamy, K, Raman, B, Harrison, EM, Wain, LV, Brightling, CE, Abel, K, Adamali, H, Adeloye, D, Adeyemi, O, Adrego, R, Jimenez, LAA, Ahmad, S, Haider, NA, Ahmed, R, Ahwireng, N, Ainsworth, M, Al-Sheklly, B, Alamoudi, A, Ali, M, Aljaroof, M, All, AM, Allan, L, Allen, RJ, Allerton, L, Allsop, L, Almeida, P, Altmann, D, Corral, MA, Amoils, S, Anderson, D, Antoniades, C, Arbane, G, Arias, A, Armour, C, Armstrong, L, Armstrong, N, Arnold, D, Arnold, H, Ashish, A, Ashworth, A, Ashworth, M, Aslani, S, Assefa-Kebede, H, Atkin, C, Atkin, P, Aung, H, Austin, L, Avram, C, Ayoub, A, Babores, M, Baggott, R, Bagshaw, J, Baguley, D, Bailey, L, Baillie, JK, Bain, S, Bakali, M, Bakau, M, Baldry, E, Baldwin, D, Ballard, C, Banerjee, A, Bang, B, Barker, RE, Barman, L, Barratt, S, Barrett, F, Basire, D, Basu, N, Bates, M, Bates, A, Batterham, R, Baxendale, H, Bayes, H, Beadsworth, M, Beckett, P, Beggs, M, Begum, M, Bell, D, Bell, R, Bennett, K, Beranova, E, Bermperi, A, Berridge, A, Berry, C, Betts, S, Bevan, E, Bhui, K, Bingham, M, Birchall, K, Bishop, L, Bisnauthsing, K, Blaikely, J, Bloss, A, Bolger, A, Bonnington, J, Botkai, A, Bourne, C, Bourne, M, Bramham, K, Brear, L, Breen, G, Breeze, J, Bright, E, Brill, S, Brindle, K, Broad, L, Broadley, A, Brookes, C, Broome, M, Brown, A, Brown, J, Brown, M, Brown, V, Brown, CW, Brugha, T, Brunskill, N, Buch, M, Buckley, P, Bularga, A, Bullmore, E, Burden, L, Burdett, T, Burn, D, Burns, G, Burns, A, Busby, J, Butcher, R, Butt, A, Byrne, S, Cairns, P, Calder, PC, Calvelo, E, Carborn, H, Card, B, Carr, C, Carr, L, Carson, G, Carter, P, Casey, A, Cassar, M, Cavanagh, J, Chablani, M, Chambers, RC, Chan, F, Channon, KM, Chapman, K, Charalambou, A, Chaudhuri, N, Checkley, A, Chen, J, Cheng, Y, Chetham, L, Childs, C, Chilvers, ER, Chinoy, H, Chiribiri, A, Chong-James, K, Choudhury, N, Chowienczyk, P, Christie, C, Chrystal, M, Clark, D, Clark, C, Clarke, J, Clohisey, S, Coakley, G, Coburn, Z, Coetzee, S, Cole, J, Coleman, C, Conneh, F, Connell, D, Connolly, B, Connor, L, Cook, A, Cooper, B, Cooper, J, Cooper, S, Copeland, D, Cosier, T, Coulding, M, Coupland, C, Cox, E, Craig, T, Crisp, P, Cristiano, D, Crooks, MG, Cross, A, Cruz, I, Cullinan, P, Cuthbertson, D, Daines, L, Dalton, M, Daly, P, Daniels, A, Dark, P, Dasgin, J, David, A, David, C, Davies, E, Davies, F, Davies, G, Davies, GA, Davies, K, Dawson, J, Daynes, E, Deakin, B, Deans, A, Deas, C, Deery, J, Defres, S, Dell, A, Dempsey, K, Denneny, E, Dennis, J, Dewar, A, Dharmagunawardena, R, Dickens, C, Dipper, A, Diver, S, Diwanji, SN, Dixon, M, Djukanovic, R, Dobson, H, Dobson, SL, Donaldson, A, Dong, T, Dormand, N, Dougherty, A, Dowling, R, Drain, S, Draxlbauer, K, Drury, K, Dulawan, P, Dunleavy, A, Dunn, S, Earley, J, Edwards, S, Edwardson, C, El-Taweel, H, Elliott, A, Elliott, K, Ellis, Y, Elmer, A, Evans, D, Evans, H, Evans, J, Evans, R, Evans, RI, Evans, T, Evenden, C, Evison, L, Fabbri, L, Fairbairn, S, Fairman, A, Fallon, K, Faluyi, D, Favager, C, Fayzan, T, Featherstone, J, Felton, T, Finch, J, Finney, S, Finnigan, J, Finnigan, L, Fisher, H, Fletcher, S, Flockton, R, Flynn, M, Foot, H, Foote, D, Ford, A, Forton, D, Fraile, E, Francis, C, Francis, R, Francis, S, Frankel, A, Fraser, E, Free, R, French, N, Fu, X, Furniss, J, Garner, L, Gautam, N, George, J, George, P, Gibbons, M, Gill, M, Gilmour, L, Gleeson, F, Glossop, J, Glover, S, Goodman, N, Goodwin, C, Gooptu, B, Gordon, H, Gorsuch, T, Greatorex, M, Greenhaff, PL, Greenhalgh, A, Greenwood, J, Gregory, H, Gregory, R, Grieve, D, Griffin, D, Griffiths, L, Guerdette, A-M, Guio, BG, Gummadi, M, Gupta, A, Gurram, S, Guthrie, E, Guy, Z, Henson, HH, Hadley, K, Haggar, A, Hainey, K, Hairsine, B, Haldar, P, Hall, I, Hall, L, Halling-Brown, M, Hamil, R, Hancock, A, Hancock, K, Hanley, NA, Haq, S, Hardwick, HE, Hardy, E, Hardy, T, Hargadon, B, Harrington, K, Harris, E, Harrison, P, Harvey, A, Harvey, M, Harvie, M, Haslam, L, Havinden-Williams, M, Hawkes, J, Hawkings, N, Haworth, J, Hayday, A, Haynes, M, Hazeldine, J, Hazelton, T, Heeley, C, Heeney, JL, Heightman, M, Henderson, M, Hesselden, L, Hewitt, M, Highett, V, Hillman, T, Hiwot, T, Hoare, A, Hoare, M, Hockridge, J, Hogarth, P, Holbourn, A, Holden, S, Holdsworth, L, Holgate, D, Holland, M, Holloway, L, Holmes, K, Holmes, M, Holroyd-Hind, B, Holt, L, Hormis, A, Hosseini, A, Hotopf, M, Howard, K, Howell, A, Hufton, E, Hughes, AD, Hughes, J, Hughes, R, Humphries, A, Huneke, N, Hurditch, E, Husain, M, Hussell, T, Hutchinson, J, Ibrahim, W, Ilyas, F, Ingham, J, Ingram, L, Ionita, D, Isaacs, K, Ismail, K, Jackson, T, James, WY, Jarman, C, Jarrold, I, Jarvis, H, Jastrub, R, Jayaraman, B, Jezzard, P, Jiwa, K, Johnson, C, Johnson, S, Johnston, D, Jolley, CJ, Jones, D, Jones, G, Jones, H, Jones, I, Jones, L, Jones, S, Jose, S, Kabir, T, Kaltsakas, G, Kamwa, V, Kanellakis, N, Kaprowska, S, Kausar, Z, Keenan, N, Kelly, S, Kemp, G, Kerslake, H, Key, AL, Khan, F, Khunti, K, Kilroy, S, King, B, King, C, Kingham, L, Kirk, J, Kitterick, P, Klenerman, P, Knibbs, L, Knight, S, Knighton, A, Kon, O, Kon, S, Kon, SS, Koprowska, S, Korszun, A, Koychev, I, Kurasz, C, Kurupati, P, Laing, C, Lamlum, H, Landers, G, Langenberg, C, Lasserson, D, Lavelle-Langham, L, Lawrie, A, Lawson, C, Layton, A, Lea, A, Lee, D, Lee, J-H, Lee, E, Leitch, K, Lenagh, R, Lewis, D, Lewis, J, Lewis, V, Lewis-Burke, N, Li, X, Light, T, Lightstone, L, Lilaonitkul, W, Lim, L, Linford, S, Lingford-Hughes, A, Lipman, M, Liyanage, K, Lloyd, A, Logan, S, Lomas, D, Loosley, R, Lota, H, Lovegrove, W, Lucey, A, Lukaschuk, E, Lye, A, Lynch, C, MacDonald, S, MacGowan, G, Macharia, I, Mackie, J, Macliver, L, Madathil, S, Madzamba, G, Magee, N, Magtoto, MM, Mairs, N, Majeed, N, Major, E, Malein, F, Malim, M, Mallison, G, Mandal, S, Mangion, K, Manisty, C, Manley, R, March, K, Marciniak, S, Marino, P, Mariveles, M, Marouzet, E, Marsh, S, Marshall, B, Marshall, M, Martin, J, Martineau, A, Martinez, LM, Maskell, N, Matila, D, Matimba-Mupaya, W, Matthews, L, Mbuyisa, A, McAdoo, S, McCall, JW, McAllister-Williams, H, McArdle, A, McArdle, P, McAulay, D, McCormick, J, McCormick, W, McCourt, P, McGarvey, L, McGee, C, Mcgee, K, McGinness, J, McGlynn, K, McGovern, A, McGuinness, H, McInnes, IB, McIntosh, J, McIvor, E, McIvor, K, McLeavey, L, McMahon, A, McMahon, MJ, McMorrow, L, Mcnally, T, McNarry, M, McNeill, J, McQueen, A, McShane, H, Mears, C, Megson, C, Megson, S, Mehta, P, Meiring, J, Melling, L, Mencias, M, Menzies, D, Morillas, MM, Michael, A, Milligan, L, Miller, C, Mills, C, Mills, NL, Milner, L, Misra, S, Mitchell, J, Mohamed, A, Mohamed, N, Mohammed, S, Molyneaux, PL, Monteiro, W, Moriera, S, Morley, A, Morrison, L, Morriss, R, Morrow, A, Moss, AJ, Moss, P, Motohashi, K, Msimanga, N, Mukaetova-Ladinska, E, Munawar, U, Murira, J, Nanda, U, Nassa, H, Nasseri, M, Neal, A, Needham, R, Neill, P, Newell, H, Newman, T, Newton-Cox, A, Nicholson, T, Nicoll, D, Nolan, CM, Noonan, MJ, Norman, C, Novotny, P, Nunag, J, Nwafor, L, Nwanguma, U, Nyaboko, J, O'Donnell, K, O'Brien, C, O'Brien, L, O'Regan, D, Odell, N, Ogg, G, Olaosebikan, O, Oliver, C, Omar, Z, Orriss-Dib, L, Osborne, L, Osbourne, R, Ostermann, M, Overton, C, Owen, J, Oxton, J, Pack, J, Pacpaco, E, Paddick, S, Painter, S, Pakzad, A, Palmer, S, Papineni, P, Paques, K, Paradowski, K, Pareek, M, Parfrey, H, Pariante, C, Parker, S, Parkes, M, Parmar, J, Patale, S, Patel, B, Patel, M, Patel, S, Pattenadk, D, Pavlides, M, Payne, S, Pearce, L, Pearl, JE, Peckham, D, Pendlebury, J, Peng, Y, Pennington, C, Peralta, I, Perkins, E, Peterkin, Z, Peto, T, Petousi, N, Petrie, J, Phipps, J, Pimm, J, Hanley, KP, Pius, R, Plant, H, Plein, S, Plekhanova, T, Plowright, M, Polgar, O, Poll, L, Porter, J, Portukhay, S, Powell, N, Prabhu, A, Pratt, J, Price, A, Price, C, Price, D, Price, L, Prickett, A, Propescu, J, Pugmire, S, Quaid, S, Quigley, J, Qureshi, H, Qureshi, IN, Radhakrishnan, K, Ralser, M, Ramos, A, Ramos, H, Rangeley, J, Rangelov, B, Ratcliffe, L, Ravencroft, P, Reddington, A, Reddy, R, Redfearn, H, Redwood, D, Reed, A, Rees, M, Rees, T, Regan, K, Reynolds, W, Ribeiro, C, Richards, A, Richardson, E, Rivera-Ortega, P, Roberts, K, Robertson, E, Robinson, E, Robinson, L, Roche, L, Roddis, C, Rodger, J, Ross, A, Ross, G, Rossdale, J, Rostron, A, Rowe, A, Rowland, A, Rowland, J, Roy, K, Roy, M, Rudan, I, Russell, R, Russell, E, Saalmink, G, Sabit, R, Sage, EK, Samakomva, T, Samani, N, Sampson, C, Samuel, K, Samuel, R, Sanderson, A, Sapey, E, Saralaya, D, Sargant, J, Sarginson, C, Sass, T, Sattar, N, Saunders, K, Saunders, P, Saunders, LC, Savill, H, Saxon, W, Sayer, A, Schronce, J, Schwaeble, W, Scott, K, Selby, N, Sewell, TA, Shah, K, Shah, P, Shankar-Hari, M, Sharma, M, Sharpe, C, Sharpe, M, Shashaa, S, Shaw, A, Shaw, K, Shaw, V, Shelton, S, Shenton, L, Shevket, K, Short, J, Siddique, S, Siddiqui, S, Sidebottom, J, Sigfrid, L, Simons, G, Simpson, J, Simpson, N, Singh, C, Singh, S, Sissons, D, Skeemer, J, Slack, K, Smith, A, Smith, D, Smith, S, Smith, J, Smith, L, Soares, M, Solano, TS, Solly, R, Solstice, AR, Soulsby, T, Southern, D, Sowter, D, Spears, M, Spencer, LG, Speranza, F, Stadon, L, Stanel, S, Steele, N, Steiner, M, Stensel, D, Stephens, G, Stephenson, L, Stern, M, Stewart, I, Stimpson, R, Stockdale, S, Stockley, J, Stoker, W, Stone, R, Storrar, W, Storrie, A, Storton, K, Stringer, E, Strong-Sheldrake, S, Stroud, N, Subbe, C, Sudlow, CL, Suleiman, Z, Summers, C, Summersgill, C, Sutherland, D, Sykes, DL, Sykes, R, Talbot, N, Tan, AL, Tarusan, L, Tavoukjian, V, Taylor, A, Taylor, C, Taylor, J, Te, A, Tedd, H, Tee, CJ, Teixeira, J, Tench, H, Terry, S, Thackray-Nocera, S, Thaivalappil, F, Thamu, B, Thickett, D, Thomas, C, Thomas, S, Thomas, AK, Thomas-Woods, T, Thompson, T, Thompson, AAR, Thornton, T, Tilley, J, Tinker, N, Tiongson, GF, Tobin, M, Tomlinson, J, Tong, C, Touyz, R, Tripp, KA, Tunnicliffe, E, Turnbull, A, Turner, E, Turner, S, Turner, V, Turner, K, Turney, S, Turtle, L, Turton, H, Ugoji, J, Ugwuoke, R, Upthegrove, R, Valabhji, J, Ventura, M, Vere, J, Vickers, C, Vinson, B, Wade, E, Wade, P, Wainwright, T, Wajero, LO, Walder, S, Walker, S, Wall, E, Wallis, T, Walmsley, S, Walsh, JA, Walsh, S, Warburton, L, Ward, TJC, Warwick, K, Wassall, H, Waterson, S, Watson, E, Watson, L, Watson, J, Welch, C, Welch, H, Welsh, B, Wessely, S, West, S, Weston, H, Wheeler, H, White, S, Whitehead, V, Whitney, J, Whittaker, S, Whittam, B, Whitworth, V, Wight, A, Wild, J, Wilkins, M, Wilkinson, D, Williams, N, Williams, J, Williams-Howard, SA, Willicombe, M, Willis, G, Willoughby, J, Wilson, A, Wilson, D, Wilson, I, Window, N, Witham, M, Wolf-Roberts, R, Wood, C, Woodhead, F, Woods, J, Wormleighton, J, Worsley, J, Wraith, D, Wright, C, Wright, L, Wright, S, Wyles, J, Wynter, I, Xu, M, Yasmin, N, Yasmin, S, Yates, T, Yip, KP, Young, B, Young, S, Young, A, Yousuf, AJ, Zawia, A, Zeidan, L, Zhao, B, Zongo, O, Group, The PHOSP-COVID Collaborative, National Institute for Health Research, and UKRI MRC COVID-19 Rapid Response Call
Subjects: Adult, Male, Pulmonary and Respiratory Medicine, Adolescent, PHOSP-COVID Collaborative Group, 1117 Public Health and Health Services, Post-Acute COVID-19 Syndrome, SDG 3 - Good Health and Well-being, Humans, Longitudinal Studies, Obesity, Prospective Studies, long COVID, Retrospective Studies, Inflammation, SARS-CoV-2, COVID-19, 1103 Clinical Sciences, Middle Aged, prospective observational study, United Kingdom, Hospitalization, Quality of Life, Female, 1199 Other Medical and Health Sciences
Abstract: Background No effective pharmacological or non-pharmacological interventions exist for patients with long COVID. We aimed to describe recovery 1 year after hospital discharge for COVID-19, identify factors associated with patient-perceived recovery, and identify potential therapeutic targets by describing the underlying inflammatory profiles of the previously described recovery clusters at 5 months after hospital discharge. Methods The Post-hospitalisation COVID-19 study (PHOSP-COVID) is a prospective, longitudinal cohort study recruiting adults (aged ≥18 years) discharged from hospital with COVID-19 across the UK. Recovery was assessed using patient-reported outcome measures, physical performance, and organ function at 5 months and 1 year after hospital discharge, and stratified by both patient-perceived recovery and recovery cluster. Hierarchical logistic regression modelling was performed for patient-perceived recovery at 1 year. Cluster analysis was done using the clustering large applications k-medoids approach using clinical outcomes at 5 months. Inflammatory protein profiling was analysed from plasma at the 5-month visit. This study is registered on the ISRCTN Registry, ISRCTN10980107, and recruitment is ongoing. Findings 2320 participants discharged from hospital between March 7, 2020, and April 18, 2021, were assessed at 5 months after discharge and 807 (32·7%) participants completed both the 5-month and 1-year visits. 279 (35·6%) of these 807 patients were women and 505 (64·4%) were men, with a mean age of 58·7 (SD 12·5) years, and 224 (27·8%) had received invasive mechanical ventilation (WHO class 7–9). The proportion of patients reporting full recovery was unchanged between 5 months (501 [25·5%] of 1965) and 1 year (232 [28·9%] of 804). Factors associated with being less likely to report full recovery at 1 year were female sex (odds ratio 0·68 [95% CI 0·46–0·99]), obesity (0·50 [0·34–0·74]) and invasive mechanical ventilation (0·42 [0·23–0·76]). Cluster analysis (n=1636) corroborated the previously reported four clusters: very severe, severe, moderate with cognitive impairment, and mild, relating to the severity of physical health, mental health, and cognitive impairment at 5 months. We found increased inflammatory mediators of tissue damage and repair in both the very severe and the moderate with cognitive impairment clusters compared with the mild cluster, including IL-6 concentration, which was increased in both comparisons (n=626 participants). We found a substantial deficit in median EQ-5D-5L utility index from before COVID-19 (retrospective assessment; 0·88 [IQR 0·74–1·00]), at 5 months (0·74 [0·64–0·88]) to 1 year (0·75 [0·62–0·88]), with minimal improvements across all outcome measures at 1 year after discharge in the whole cohort and within each of the four clusters. Interpretation The sequelae of a hospital admission with COVID-19 were substantial 1 year after discharge across a range of health domains, with the minority in our cohort feeling fully recovered. Patient-perceived health-related quality of life was reduced at 1 year compared with before hospital admission. Systematic inflammation and obesity are potential treatable traits that warrant further investigation in clinical trials. Funding UK Research and Innovation and National Institute for Health Research.
Published: 2022
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37. Novel Glibenclamide–Phospholipid Complex for Diabetic Treatment: Formulation, Physicochemical Characterization, and in-vivo Evaluation

Author: Sandeep Rathor and DC Bhatt
Subjects: General Pharmacology, Toxicology and Pharmaceutics
Published: 2022
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38. The Benefit of Bariatric Surgery on Histological Features of Metabolic Associated Fatty Liver Disease Assessed Through Noninvasive Methods

Author: Diego Meneses, Antonio Olveira, Ramón Corripio, María dC Méndez, Míriam Romero, Isabel Calvo-Viñuelas, Noemí González-Pérez-de-Villar, and Ana I. de-Cos-Blanco
Subjects: Liver Cirrhosis, Nutrition and Dietetics, Liver, Non-alcoholic Fatty Liver Disease, Biopsy, Endocrinology, Diabetes and Metabolism, Bariatric Surgery, Humans, Surgery, Prospective Studies, gamma-Glutamyltransferase, Fibrosis, Obesity, Morbid
Abstract: In patients with clinically severe obesity, metabolic associated fatty liver disease (MAFLD) and steatohepatitis are highly prevalent. There is a lack of prospective studies evaluating the impact of bariatric surgery (BS) on MAFLD using both noninvasive and histological criteria. The present study aims to assess the impact of BS on MAFLD using histological and biochemical criteria.This is a prospective study of 52 patients subjected to BS. Noninvasive fibrosis risk scores (NIFRS) along with anthropometric, clinical, and biochemical parameters were recorded pre- and 12 months post-BS. Liver biopsy was obtained in all individuals at baseline (wedge biopsy) and was repeated at 12 months (percutaneous Tru-cut) in those diagnosed with steatohepatitis. The primary outcome was the change in the degree of steatohepatitis and fibrosis. The secondary outcome was the change in scores for hepatocellular ballooning, lobular inflammation, steatosis, and fibrosis.One year after BS, steatohepatitis resolved in core biopsies with no worsening of fibrosis in 95.7% of individuals (n = 21, 95% CI: 87.3-100), and 13 (56.5%) exhibited complete resolution. Of 15 patients with fibrosis at baseline, 13 (86.7%) showed improvement and 12 exhibited fibrosis resolution. The values of transaminases improved, but only gamma glutamyl transferase (GGT) showed statistical significance. Among the NIFRS, NAFLD fibrosis score (NFS) and Hepamet fibrosis score (HFS) showed significant improvement.In the setting it was studied, BS improved or resolved steatohepatitis and fibrosis in patients with obesity. NIFRS, especially NFS and HFS, and levels of GGT could be used as markers of recovery of liver function after BS.
Published: 2022
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39. Length–biomass equations to allow rapid assessment of semi-aquatic bug biomass in tropical streams

Author: Harianja, MF, Luke, SH, Barclay, H, Chey, VK, Aldridge, DC, Foster, WA, Turner, EC, Harianja, MF [0000-0002-9607-6151], Luke, SH [0000-0002-8335-5960], Barclay, H [0000-0002-0027-2570], Chey, VK [0000-0003-3038-9494], Aldridge, DC [0000-0001-9067-8592], Turner, EC [0000-0003-2715-2234], and Apollo - University of Cambridge Repository
Subjects: Hemiptera, indicator species, life stages, length-biomass relationships, body forms, Gerromorpha, bioindicator, power regression, semi-aquatic bugs, water quality, habitat disturbance, Sabah
Abstract: Funder: Cambridge Trust; Id: http://dx.doi.org/10.13039/501100003343, Funder: Cambridge University Commonwealth Fund, Funder: Hanne and Torkel Weis‐Fogh Fund, Funder: Jardine Foundation, Funder: Panton Trust, Funder: Proforest, Funder: S.T. Lee Fund, Funder: Tim Whitmore Fund, Funder: Varley Gradwell Travelling Fellowship, 1. Length-biomass equations are relatively easy and cost-effective for deriving insect biomass. However, the exact relationship can vary between taxa and geographical regions. 2. Semi-aquatic bugs are abundant and are indicators of freshwater quality, but there are no studies investigating the effect of habitat disturbance on their biomass, although it is useful in assessing ecological processes. 3. We identified the best-fit length-biomass models to predict the biomass of semi-aquatic bugs (Gerromorpha, Hemiptera) collected from streams in Sabah, Malaysia. 4. We used 259 juvenile and adult semi-aquatic bugs to compare a range of plausible length-biomass functions, and to assess whether relationships differed across the following families and body forms: a.Cylindrostethinae, Gerrinae, and Ptilomerinae, which are subfamilies within Gerridae consisting of small to large bugs that have long and slender bodies, b. Halobatinae, a subfamily within Gerridae, consisting of small to medium-sized bugs with wide heads and thoraxes as well as short abdomens, and c. Veliidae, which are small bugs with stout bodies. 5. Estimation used five fitting functions (linear regression; polynomial regression order two, three, and four; and power regression) on the following groupings: three body forms combined; each body form with life stages (juvenile and adult) combined; and each body form with life stages separated. 6. Power regressions were the best fit in predicting the biomass of semi-aquatic bugs across life stages and body forms, and the predictive power of models was higher when the biomass of different body forms was calculated separately (specifically for Halobatinae and Veliidae). Splitting by life stages did not always result in additional improvement. 7. The equations from this study expand the scope of possible future ecological research on semi-aquatic bugs, particularly in Southeast Asia, by allowing more studies to consider biomass-related questions., Jardine Foundation, the Cambridge Trust, Proforest, the Varley Gradwell Travelling Fellowship, the Tim Whitmore Fund, the Panton Trust, the Cambridge University Commonwealth Fund, the Hanne and Torkel Weis-Fogh Fund, the S.T. Lee Fund
Published: 2022
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40. Two-particle Bose–Einstein correlations in pp collisions at √s=13 TeV measured with the ATLAS detector at the LHC

Author: Aad, G, Abbott, B, Abbott, DC, Abed Abud, A, Abeling, K, Abhayasinghe, DK, Abidi, SH, AbouZeid, OS, Abraham, NL, Abramowicz, H, Abreu, H, Abulaiti, Y, Acharya, BS, Achkar, B, Adachi, S, Adam, L, Adam Bourdarios, C, Adamczyk, L, Adamek, L, Adelman, J, Adersberger, M, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agapopoulou, C, Agaras, MN, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmadov, F, Ahmed, WS, Ai, X, Aielli, G, Akatsuka, S, Åkesson, TPA, Akilli, E, Akimov, AV, Khoury, KA, Alberghi, GL, Albert, J, Alconada Verzini, MJ, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexandre, D, Alexopoulos, T, Alfonsi, A, Alhroob, M, Ali, B, Alimonti, G, Alison, J, Alkire, SP, Allaire, C, Allbrooke, BMM, Allen, BW, Allport, PP, Aloisio, A, Alonso, A, Alonso, F, Alpigiani, C, Alshehri, AA, Alvarez Estevez, M, Álvarez Piqueras, D, Alviggi, MG, Amaral Coutinho, Y, Ambler, A, Ambroz, L, Amelung, C, Amidei, D, Amor Dos Santos, SP, Amoroso, S, Amrouche, CS, An, F, Anastopoulos, C, Andari, N, Andeen, T, Anders, CF, Anders, JK, Andreazza, A, Andrei, V, Anelli, CR, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aparisi Pozo, JA, Aperio Bella, L, Arabidze, G, Araque, JP, Araujo Ferraz, V, Araujo Pereira, R, Aad, G [0000-0002-6665-4934], Abbott, B [0000-0002-5888-2734], Abbott, DC [0000-0002-7248-3203], Abed Abud, A [0000-0002-2788-3822], Abeling, K [0000-0002-1002-1652], Abhayasinghe, DK [0000-0002-2987-4006], Abidi, SH [0000-0002-8496-9294], AbouZeid, OS [0000-0002-8279-9324], Abramowicz, H [0000-0001-5329-6640], Abreu, H [0000-0002-1599-2896], Abulaiti, Y [0000-0003-0403-3697], Acharya, BS [0000-0002-8588-9157], Achkar, B [0000-0002-0288-2567], Adachi, S [0000-0002-0400-7555], Adam, L [0000-0001-6005-2812], Adam Bourdarios, C [0000-0002-2634-4958], Adamczyk, L [0000-0002-5859-2075], Adamek, L [0000-0003-1562-3502], Adelman, J [0000-0002-1041-3496], Adiguzel, A [0000-0001-6644-0517], Adorni, S [0000-0003-3620-1149], Adye, T [0000-0003-0627-5059], Affolder, AA [0000-0002-9058-7217], Afik, Y [0000-0001-8102-356X], Agapopoulou, C [0000-0002-2368-0147], Agaras, MN [0000-0002-4355-5589], Aggarwal, A [0000-0002-1922-2039], Agheorghiesei, C [0000-0003-3695-1847], Aguilar-Saavedra, JA [0000-0002-5475-8920], Ahmadov, F [0000-0003-3644-540X], Ahmed, WS [0000-0003-0128-3279], Ai, X [0000-0003-3856-2415], Aielli, G [0000-0002-0573-8114], Akatsuka, S [0000-0002-1681-6405], Åkesson, TPA [0000-0003-4141-5408], Akilli, E [0000-0003-1309-5937], Akimov, AV [0000-0002-2846-2958], Khoury, KA [0000-0002-0547-8199], Alberghi, GL [0000-0003-2388-987X], Albert, J [0000-0003-0253-2505], Alconada Verzini, MJ [0000-0003-2212-7830], Alderweireldt, S [0000-0002-8224-7036], Aleksa, M [0000-0002-1936-9217], Aleksandrov, IN [0000-0001-7381-6762], Alexa, C [0000-0003-0922-7669], Alexopoulos, T [0000-0002-8977-279X], Alfonsi, A [0000-0001-7406-4531], Alhroob, M [0000-0001-7569-7111], Ali, B [0000-0001-8653-5556], Alimonti, G [0000-0002-7128-9046], Alison, J [0000-0003-0843-1641], Allaire, C [0000-0003-4745-538X], Allbrooke, BMM [0000-0002-5738-2471], Allen, BW [0000-0002-1783-2685], Allport, PP [0000-0001-7303-2570], Aloisio, A [0000-0002-3883-6693], Alonso, A [0000-0003-1259-0573], Alonso, F [0000-0001-9431-8156], Alpigiani, C [0000-0002-7641-5814], Alvarez Estevez, M [0000-0002-8181-6532], Álvarez Piqueras, D [0000-0002-5193-1492], Alviggi, MG [0000-0003-0026-982X], Amaral Coutinho, Y [0000-0002-1798-7230], Ambler, A [0000-0003-2184-3480], Ambroz, L [0000-0002-0987-6637], Amidei, D [0000-0002-6814-0355], Amor Dos Santos, SP [0000-0001-7566-6067], Amoroso, S [0000-0001-5450-0447], An, F [0000-0002-3675-5670], Anastopoulos, C [0000-0003-1587-5830], Andari, N [0000-0002-4935-4753], Andeen, T [0000-0002-4413-871X], Anders, CF [0000-0001-6632-6327], Anders, JK [0000-0002-1846-0262], Andreazza, A [0000-0001-5161-5759], Angelidakis, S [0000-0002-8274-6118], Angerami, A [0000-0001-7834-8750], Anisenkov, AV [0000-0002-7201-5936], Annovi, A [0000-0002-4649-4398], Antel, C [0000-0001-9683-0890], Anthony, MT [0000-0002-5270-0143], Antonelli, M [0000-0002-2293-5726], Antrim, DJA [0000-0001-8084-7786], Anulli, F [0000-0003-2734-130X], Aoki, M [0000-0001-7498-0097], Aparisi Pozo, JA [0000-0001-7401-4331], Aperio Bella, L [0000-0003-3942-1702], Araque, JP [0000-0003-2927-9378], Araujo Ferraz, V [0000-0003-1177-7563], and Apollo - University of Cambridge Repository
Subjects: Quantum Physics, Particle and Plasma Physics, Regular Article - Experimental Physics, hep-ex, Molecular, Nuclear, High Energy Physics::Experiment, Nuclear Experiment, Atomic, Nuclear & Particles Physics
Abstract: This paper presents studies of Bose-Einstein correlations (BEC) in proton-proton collisions at a centre-of-mass energy of 13 TeV, using data from the ATLAS detector at the CERN Large Hadron Collider. Data were collected in a special low-luminosity configuration with a minimum-bias trigger and a high-multiplicity track trigger, accumulating integrated luminosities of 151 $\mu$b$^{-1}$ and 8.4 nb$^{-1}$ respectively. The BEC are measured for pairs of like-sign charged particles, each with $|\eta|$ < 2.5, for two kinematic ranges: the first with particle $p_T$ > 100 MeV and the second with particle $p_T$ > 500 MeV. The BEC parameters, characterizing the source radius and particle correlation strength, are investigated as functions of charged-particle multiplicity (up to 300) and average transverse momentum of the pair (up to 1.5 GeV). The double-differential dependence on charged-particle multiplicity and average transverse momentum of the pair is also studied. The BEC radius is found to be independent of the charged-particle multiplicity for high charged-particle multiplicity (above 100), confirming a previous observation at lower energy. This saturation occurs independent of the transverse momentum of the pair.
Published: 2022
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41. In utero origin of myelofibrosis presenting in adult monozygotic twins

Author: Sousos, N, Ní Leathlobhair, M, Simoglou Karali, C, Louka, E, Bienz, N, Royston, D, Clark, S-A, Hamblin, A, Howard, K, Mathews, V, George, B, Roy, A, Psaila, B, Wedge, DC, and Mead, AJ
Subjects: Myeloproliferative Disorders, Primary Myelofibrosis, Mutation, Humans, Twins, Monozygotic, General Medicine, Janus Kinase 2, Calreticulin, General Biochemistry, Genetics and Molecular Biology
Abstract: The latency between acquisition of an initiating somatic driver mutation by a single-cell and clinical presentation with cancer is largely unknown. We describe a remarkable case of monozygotic twins presenting with CALR mutation-positive myeloproliferative neoplasms (MPNs) (aged 37 and 38 years), with a clinical phenotype of primary myelofibrosis. The CALR mutation was absent in T cells and dermal fibroblasts, confirming somatic acquisition. Whole-genome sequencing lineage tracing revealed a common clonal origin of the CALR-mutant MPN clone, which occurred in utero followed by twin-to-twin transplacental transmission and subsequent similar disease latency. Index sorting and single-colony genotyping revealed phenotypic hematopoietic stem cells (HSCs) as the likely MPN-propagating cell. Furthermore, neonatal blood spot analysis confirmed in utero origin of the JAK2V617F mutation in a patient presenting with polycythemia vera (aged 34 years). These findings provide a unique window into the prolonged evolutionary dynamics of MPNs and fitness advantage exerted by MPN-associated driver mutations in HSCs.
Published: 2022
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42. Scratch that itch: Farrowing crate scratching enrichment for sows

Author: RK Pritchett, BN Gaskill, MA Erasmus, JS Radcliffe, and DC Lay
Subjects: General Veterinary, Animal Science and Zoology, General Biochemistry, Genetics and Molecular Biology
Abstract: Developing effective enrichments is important for improving pig (Sus scrofa) welfare as it increases species-specific behaviours, decreases abnormal behaviours, and increases time active. However, few enrichments are available for sows in farrowing crates. Pigs are often observed to scratch, or rub against objects, however enrichments designed to provide a scratching outlet have never been tested in sows. We examined the behaviour and welfare of sows in farrowing crates when they were presented with one of two types of scratchpad enrichment. Sows (n = 18) of parities two (P2) and three (P3) were housed for 25 days and assigned no enrichment (Control) or a scratch-pad made of plastic mats (Plastic) or coir fibre mats (Fibre). Parity two Plastic sows scratched for a longer total duration than P2 and P3 Fibre sows, P3 Plastic sows, and P2 Control sows. Parity two Plastic sows also displayed scratching bouts more frequently than all except P3 Control sows. There were no body lesion differences between treatments. Abnormal behaviour and proportion of time spent in different postures also did not differ between treatments. Plastic scratch-pads may be a suitable enrichment for farrowing crates as they increased the natural behaviour of scratching. More research is needed to refine the scratch-pad design and measure motivation before it can be concluded that scratch-pads are a successful enrichment that should be implemented on-farm.
Published: 2022
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43. Labour absorption in livestock activities in arid Western and Northern region ofRajasthan

Author: Arjun Singh Rajput, Latika Sharma, GL Meena, SS Burark, DC Pant, and S Mishra
Subjects: General Chemical Engineering
Abstract: In the arid western and northern regions of Rajasthan livestock activity is a complementary activity to farming and it provides much needed risk cover in case of crop failure. The present investigation was undertaken to study the labour absorption in different livestock activities in Arid western and northern regions of Rajasthan. The study was conducted based on primary data. The primary data were collected from the 200 households of 10 villages during year of the 2018-2019. The average utilization of human labour in livestock activities was found 54.48 man-days/animal/year in arid western and northern region. The participation of woman labour in all livestock activities was found more than man labour in all herd size group in arid western and northern region. The annual average human labour absorption was maximum in site preparation activity i.e., 28.76 hours/animal/year for male and 101.63 hours/animal/year for female, then other activities in all size of farms.
Published: 2022
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44. Variation in the COVID-19 infection–fatality ratio by age, time, and geography during the pre-vaccine era: a systematic analysis

Author: Sorensen, Rjd, Barber, Rm, Pigott, Dm, Carter, A, Spencer, Cn, Ostroff, Sm, Reiner, Rc, Abbafati, C, Adolph, C, Allorant, A, Amlag, Jo, Aravkin, Ay, Bachmeier, Sd, Bang-Jensen, Bl, Bisignano, C, Bloom, Ss, Castellano, R, Castro, E, Collins, Jk, Comfort, H, Dai, Xc, Dangel, Wj, Dapper, C, Deen, A, Earl, L, Erickson, M, Ewald, Sb, Ferrari, Aj, Flaxman, Ad, Frostad, Jj, Fullman, N, Gamkrelidze, A, Giles, Jr, Guo, Gr, Jw, He, Helak, M, Hulland, En, Huntley, Bm, Kereselidze, M, Lazzar-Atwood, A, Legrand, Ke, Lindstrom, A, Linebarger, E, Lozano, R, Magistro, B, Malta, Dc, Mansson, J, Herrera, Amm, Marinho, F, Mirkuzie, Ah, Mokdad, Ah, Monasta, L, Naghavi, M, Nassereldine, H, Nomura, S, Odell, Cm, Olana, Lt, Pasovic, M, Pease, Sa, Penberthy, L, Reinke, G, Ribeiro, Alp, Santomauro, Df, Sholokhov, A, Skhvitaridze, N, Spurlock, Ee, Syailendrawati, R, Topor-Madry, R, At, Vo, Vos, T, Walcott, R, Walker, A, Watson, S, Wiysonge, Cs, Worku, Na, Zheng, P, Hay, Si, Gakidou, E, and Murray, Cjl
Subjects: infection fatality ratio, covid, General Medicine, vaccination
Published: 2022
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45. Effects of Processing Methods on the Chemical Properties of Sprouting Leaf (Bryophyllum Pinnatum)

Author: Omah EC, Ugwu CE, Nweze BC, Akah NP, and Ofoegbu DC
Abstract: This study was carried out to determine the effects of processing methods on the chemical properties of sprouting leaf (Bryophyllum pinnatum). Fresh leaves of B. pinnatum “Oda opue” were collected, destalked, sorted, washed and drained. The prepared samples were divided into four portions. Three portions were processed by sun drying (14hrs), shade drying (7days) and blanching (90oC for 2mins), the fresh leaves that were neither dried nor blanched served as control. The sun-dried leaf (DL), shade dried leaf (SD), blanched leaf (BL) and the fresh leaf (FL) where analyzed for proximate, vitamin, mineral and phytochemical compositions. The proximate composition ranged as follows; moisture content (8.94 to 89.57%), protein (4.50 to 22.0%), ash (0.81 to 13.81%), fibre (0.84 to 6.86%), fat (0.21 to 2.06%), and carbohydrate (3.52 to 48.57%). The vitamin A content which ranged from 1.40 to 3.92 mg/100g was highest in shade dried leave. Vitamin B1 and C ranged from 210.00 to 295.40 mg/100 g and 18.25 to 27.60 mg/100g, respectively with the shade dried leaves having the highest value. The mineral composition; calcium, magnesium, zinc and iron were highest in shade dried leaf sample and was significantly (p < 0.05) different from fresh, sun dry, and blanched leaves samples. The phytochemical composition ranged from 0.17 to 0.44, 0.60 to 0.85% for saponin and alkaloid, 0.34 to 1.05, 0.17 to 0.58, 0.29 to 0.54 mg/100g and 0.32 to 0.70% for oxalate, phytate, tannin and flavonoid, respectively. The shade dried leaves was found to have higher nutritional composition.
Published: 2022
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46. Monocyte secretory profiling in a clinical and MEFV genotype-characterized cohort of Danish familial Mediterranean fever patients: diagnostic potential of CCL1 and CXCL1

Author: SB Mortensen, AE Hansen, K-E Byg, L Diederichsen, C Schade Larsen, MI Goldschmidt, MA Jakobsen, K Assing, KL Lambertsen, DC Andersen, and IS Johansen
Subjects: Rheumatology, Immunology, Immunology and Allergy, General Medicine
Abstract: Objective: The autoinflammatory disease familial Mediterranean fever (FMF), characterized by recurrent attacks of sterile fever, serosal, and/or synovial inflammation, is caused by variants in the Mediterranean fever gene, MEFV, coding for the pyrin inflammasome sensor. The diagnosis of FMF is mainly based on clinical symptoms and confirmed by detection of disease-associated MEFV variants. However, the diagnosis is challenging among patients carrying variants of uncertain clinical significance (VUS). In this study, we aimed to identify potential FMF discriminatory diagnostic markers in a cohort of clinically characterized FMF patients. Method: We established a cohort of clinically and MEFV genotype-characterized FMF patients by enrolling patients from major Danish hospitals (n = 91). The secretory profile of pyrin inflammasome-activated monocytes from healthy donors (HDs) and MEFV-characterized FMF patients (n = 28) was assessed by analysing cell supernatants for a custom-designed panel of 23 cytokines, chemokines, and soluble tumour necrosis factor receptors associated with monocyte and macrophage function. Results: MEFV genotypes in Danish FMF patients were associated with age at symptom onset (p
Published: 2022
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47. Opportune management of a patient with a macrodont and supernumerary tooth

Author: CYS Low, DC‐V Ong, and E Freer
Subjects: General Dentistry
Published: 2022
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48. A disease-associated gene desert orchestrates macrophage inflammatory responses via ETS2

Author: CT Stankey, C Bourges, T Turner-Stokes, AP Piedade, C Palmer-Jones, I Papa, M Dos Silva dos Santos, LO Randzavola, L Speidel, EC Parkes, W Edwards, AP Rochford, CD Murray, JI MacRae, P Skoglund, C Wallace, MZ Cader, DC Thomas, and JC Lee
Abstract: Increasing global rates of autoimmune and inflammatory disease present a burgeoning threat to human health1. This is compounded by the limited efficacy of available treatments1and high failure rates during drug development2– underscoring an urgent need to better understand disease mechanisms. Here we show how genetics could address this challenge. By investigating an intergenic haplotype on chr21q22, independently linked to inflammatory bowel disease (IBD), ankylosing spondylitis, primary sclerosing cholangitis and Takayasu’s arteritis3–6, we discover that the causal gene,ETS2, is a master regulator of inflammatory responses in human macrophages and delineate how the risk haplotype increasesETS2expression. Genes regulated by ETS2 were prominently expressed in affected tissues from chr21q22-associated diseases and more enriched for IBD GWAS hits than almost all previously described pathways. OverexpressingETS2in resting macrophages produced an activated effector state that phenocopied intestinal macrophages from IBD7, with upregulation of multiple drug targets including TNFα and IL-23. Using a database of cellular signatures8, we identify drugs that could modulate this pathway and validate the potent anti-inflammatory activity of one class of small moleculesin vitroandex vivo. Together, this highlights the potential for common genetic associations to improve both the understanding and treatment of human disease.
Published: 2023
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49. Measurement of the total and differential Higgs boson production cross-sections at √s = 13 TeV with the ATLAS detector by combining the H → ZZ * → 4ℓ and H → γγ decay channels

Author: Aad, G, Abbott, B, Abbott, DC, Abeling, K, Abidi, SH, Aboulhorma, A, Abramowicz, H, Abreu, H, Abulaiti, Y, Abusleme Hoffman, AC, Acharya, BS, Achkar, B, Adam Bourdarios, C, Adamczyk, L, Adamek, L, Addepalli, SV, Adelman, J, Adiguzel, A, Adorni, S, Adye, T, Affolder, AA, Afik, Y, Agaras, MN, Agarwala, J, Aggarwal, A, Agheorghiesei, C, Aguilar-Saavedra, JA, Ahmad, A, Ahmadov, F, Ahmed, WS, Ahuja, S, Ai, X, Aielli, G, Aizenberg, I, Akbiyik, M, Åkesson, TPA, Akimov, AV, Al Khoury, K, Alberghi, GL, Albert, J, Albicocco, P, Alderweireldt, S, Aleksa, M, Aleksandrov, IN, Alexa, C, Alexopoulos, T, Alfonsi, A, Alfonsi, F, Alhroob, M, Ali, B, Ali, S, Aliev, M, Alimonti, G, Alkakhi, W, Allaire, C, Allbrooke, BMM, Allport, PP, Aloisio, A, Alonso, F, Alpigiani, C, Alunno Camelia, E, Alvarez Estevez, M, Alviggi, MG, Aly, M, Amaral Coutinho, Y, Ambler, A, Amelung, C, Amerl, M, Ames, CG, Amidei, D, Amor Dos Santos, SP, Amoroso, S, Amos, KR, Ananiev, V, Anastopoulos, C, Andeen, T, Anders, JK, Andrean, SY, Andreazza, A, Angelidakis, S, Angerami, A, Anisenkov, AV, Annovi, A, Antel, C, Anthony, MT, Antipov, E, Antonelli, M, Antrim, DJA, Anulli, F, Aoki, M, Aoki, T, Aparisi Pozo, JA, Aparo, MA, Aperio Bella, L, Appelt, C, Aranzabal, N, Araujo Ferraz, V, Arcangeletti, C, Arce, ATH, Arena, E, and Apollo - University of Cambridge Repository
Subjects: 5106 Nuclear and Plasma Physics, 51 Physical Sciences, 5107 Particle and High Energy Physics
Abstract: The total and differential Higgs boson production cross-sections are measured through a combined statistical analysis of the H → ZZ* → 4ℓ and H → γγ decay channels. The results are based on a dataset of 139 fb−1 of proton–proton collisions at a centre-of-mass energy of 13 TeV, recorded by the ATLAS detector at the Large Hadron Collider. The measured total Higgs boson production cross-section is $$ {55.5}_{-3.8}^{+4.0} $$ 55.5 − 3.8 + 4.0 pb, consistent with the Standard Model prediction of 55.6 ± 2.5 pb. All results from the two decay channels are compatible with each other, and their combination agrees with the Standard Model predictions. A combined statistical interpretation of the measured fiducial cross-sections as a function of the Higgs boson transverse momentum is performed in order to probe the Yukawa couplings to the bottom and charm quarks. A similar interpretation is performed by including also the constraints from the measurements of Higgs boson production in association with a W or Z boson in the H →$$ b\overline{b} $$ b b ¯ and $$ c\overline{c} $$ c c ¯ decay channels.
Published: 2023

50. Prediction and Categorization Of COVID-19 Related Dermatological Manifestations Using Machine Learning

Author: Dr. Shubhangi DC, Dr. M.A Waheed2, Nameera Simran, Nameera Simran, and Dr. Basavaraj Gadgay
Subjects: COVID-19 erythematous/maculopapular/morbilliform
Abstract: COVID-19 is global epidemic instigated because of "severe acute respiratory syndrome corona virus 2" .Fever, cough, tiredness, dyspnea, and hypogeusia/ hyposmia are all common signs. Dermatological indications have become more common in recent months among the extrapulmonary indicators associated with COVID-19. Our group proposed a taxonomy based on the polymorphic character of COVID-19-related cutaneous symptoms, which includes the following six primary clinical patterns:Urticarial rash, confluent erythematous / maculopapular / morbilliform rash, papulovesicular exanthem, chilblain-like acral, livedo reticularis / racemosa-like, purpuric "vasculitic" patterns. To offer an evaluation of possible pathophysiological routes of COVID-19- related cutaneous symptoms, this research focuses upon that clinical features & therapeutic treatment of every category. Machine learning algorithms such as SVM, RF, DT, KNN, LR, and NB are used in the analysis.
Published: 2023
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