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Managing wildlife populations in the face of global change requires regular data on the abundance and distribution of wild animals, but acquiring these over appropriate spatial scales in a sustainable way has proven challenging. Here we present the data from Snapshot USA 2020, a second annual national mammal survey of the USA. This project involved 152 scientists setting camera traps in a standardized protocol at 1485 locations across 103 arrays in 43 states for a total of 52,710 trap-nights of survey effort. Most (58) of these arrays were also sampled during the same months (September and October) in 2019, providing a direct comparison of animal populations in 2 years that includes data from both during and before the COVID-19 pandemic. All data were managed by the eMammal system, with all species identifications checked by at least two reviewers. In total, we recorded 117,415 detections of 78 species of wild mammals, 9236 detections of at least 43 species of birds, 15,851 detections of six domestic animals and 23,825 detections of humans or their vehicles. Spatial differences across arrays explained more variation in the relative abundance than temporal variation across years for all 38 species modeled, although there are examples of significant site-level differences among years for many species. Temporal results show how species allocate their time and can be used to study species interactions, including between humans and wildlife. These data provide a snapshot of the mammal community of the USA for 2020 and will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, and the impacts of species interactions on daily activity patterns. There are no copyright restrictions, and please cite this paper when using these data, or a subset of these data, for publication.

This abstract seeks to introduce the ISSAC community to the DEWCAD project, which is based at Coventry University and the University of Bath, in the United Kingdom. The project seeks to push back the Doubly Exponential Wall of Cylindrical Algebraic Decomposition, through the integration of SAT/SMT technology, the extension of Lazard projection theory, and the development of new algorithms based on CAD technology but without producing CADs themselves. The project also seeks to develop applications of CAD and will focus on applications in the domains of economics and bio-network analysis., Comment: 5 pages. Accepted as short communication at ISSAC 2021

The goal of this white paper is to identify and describe promising key research goals to aid the theoretical characterization and observational detection of ionizing radiation from quiescent and flaring upper atmospheres of planet hosts as well as properties of stellar coronal mass ejections (CMEs) and stellar energetic particle (SEP) events.

The field of exoplanetary science is making rapid progress both in statistical studies of exoplanet properties as well as in individual characterization. As space missions provide an emerging picture of formation and evolution of exoplanetary systems, the search for habitable worlds becomes one of the fundamental issues to address. To tackle such a complex challenge, we need to specify the conditions favorable for the origin, development and sustainment of life as we know it. This requires the understanding of global (astrospheric) and local (atmospheric, surface and internal) environments of exoplanets in the framework of the physical processes of the interaction between evolving planet-hosting stars along with exoplanetary evolution over geological timescales, and the resulting impact on climate and habitability of exoplanets. Feedbacks between astrophysical, physico-chemical atmospheric and geological processes can only be understood through interdisciplinary studies with the incorporation of progress in heliophysics, astrophysics, planetary, Earth sciences, astrobiology, and the origin of life communities. The assessment of the impacts of host stars on the climate and habitability of terrestrial (exo)planets and potential exomoons around them may significantly modify the extent and the location of the habitable zone and provide new directions for searching for signatures of life. Thus, characterization of stellar ionizing outputs becomes an important task for further understanding the extent of habitability in the universe. The goal of this white paper is to identify and describe promising key research goals to aid the theoretical characterization and observational detection of ionizing radiation from quiescent and flaring upper atmospheres of planet hosts as well as properties of stellar coronal mass ejections and stellar energetic particle events., Comment: White Paper submitted to the Astronomy and Astrophysics Decadal Survey (Astro2020), 8 pages, 1 figure

We consider problems originating in economics that may be solved automatically using mathematical software. We present and make freely available a new benchmark set of such problems. The problems have been shown to fall within the framework of non-linear real arithmetic, and so are in theory soluble via Quantifier Elimination (QE) technology as usually implemented in computer algebra systems. Further, they all can be phrased in prenex normal form with only existential quantifiers and so are also admissible to those Satisfiability Module Theory (SMT) solvers that support the QF_NRA. There is a great body of work considering QE and SMT application in science and engineering, but we demonstrate here that there is potential for this technology also in the social sciences., Comment: To appear in Proc. SC-Square 2018. Dataset described is hosted by Zenodo at: https://doi.org/10.5281/zenodo.1226892 . arXiv admin note: substantial text overlap with arXiv:1804.10037

We consider the use of Quantifier Elimination (QE) technology for automated reasoning in economics. There is a great body of work considering QE applications in science and engineering but we demonstrate here that it also has use in the social sciences. We explain how many suggested theorems in economics could either be proven, or even have their hypotheses shown to be inconsistent, automatically via QE. However, economists who this technology could benefit are usually unfamiliar with QE, and the use of mathematical software generally. This motivated the development of a Mathematica Package TheoryGuru, whose purpose is to lower the costs of applying QE to economics. We describe the package's functionality and give examples of its use., Comment: To appear in Proc ICMS 2018

Symbolic Computation and Satisfiability Checking are two research areas, both having their individual scientific focus but sharing also common interests in the development, implementation and application of decision procedures for arithmetic theories. Despite their commonalities, the two communities are rather weakly connected. The aim of our newly accepted SC2 project (H2020-FETOPEN-CSA) is to strengthen the connection between these communities by creating common platforms, initiating interaction and exchange, identifying common challenges, and developing a common roadmap from theory along the way to tools and (industrial) applications. In this paper we report on the aims and on the first activities of this project, and formalise some relevant challenges for the unified SC2 community.

Symbolic Computation and Satisfiability Checking are two research areas, both having their individual scientific focus but sharing also common interests in the development, implementation and application of decision procedures for arithmetic theories. Despite their commonalities, the two communities are rather weakly connected. The aim of our newly accepted SC2 project (H2020-FETOPEN-CSA) is to strengthen the connection between these communities by creating common platforms, initiating interaction and exchange, identifying common challenges, and developing a common roadmap from theory along the way to tools and (industrial) applications. In this paper we report on the aims and on the first activities of this project, and formalise some relevant challenges for the unified SC2 community.

We have examined polycrystalline MgB2 by electron energy loss spectroscopy (EELS) and density of state calculations. In particular, we have studied two different crystal orientations, [110] and [001] with respect to the incident electron beam direction, and found significant changes in the near-edge fine-structure of the B K-edge. Density functional theory suggests that the pre-peak of the B K-edge core loss is composed of a mixture of pxy and pz hole states and we will show that these contributions can be distinguished only with an experimental energy resolution better than 0.5 eV. For conventional TEM/STEM instruments with an energy resolution of ~1.0 eV the pre-peak still contains valuable information about the local charge carrier concentration that can be probed by core-loss EELS. By considering the scattering momentum transfer for different crystal orientations, it is possible to analytically separate pxy and pz components from of the experimental spectra With careful experiments and analysis, EELS can be a unique tool measuring the superconducting properties of MgB2, doped with various elements for improved transport properties on a sub-nanometer scale., Comment: 26 Pages, 5 figures, 1 table. Submited to PRB

We recently started the Formalin project to create a formal version of the C99 standard for the C programming language. We are writing three matching formalizations for the interactive theorem provers HOL4, Isabelle/HOL and Coq, that all closely follow the existing C99 standard text. The project runs from 2011 to 2015, and involves a full time PhD student, a half time researcher and several scientific advisors. The project differs from existing work in that our aim is to formalize the full C99 standard. This means that we treat the C preprocessor, the C standard library, floating point arithmetic, and 'dirty' C features like signal handling and volatile variables. Importantly, this means we also treat embedded C programs without explicit input/output.

Floating point operations are fast, but require continuous effort on the part of the user in order to ensure that the results are correct. This burden can be shifted away from the user by providing a library of exact analysis in which the computer handles the error estimates. We provide an implementation of the exact real numbers in the Coq proof assistant. This improves on the earlier Coq-implementation by O'Connor in two ways: we use dyadic rationals built from the machine integers and we optimize computation of power series by using approximate division. Moreover, we use type classes for clean mathematical interfaces. This appears to be the first time that type classes are used in heavy computation. We obtain over a 100 times speed up of the basic operations and indications for improving the Coq system.

We present several steps towards large formal mathematical wikis. The Coq proof assistant together with the CoRN repository are added to the pool of systems handled by the general wiki system described in \cite{DBLP:conf/aisc/UrbanARG10}. A smart re-verification scheme for the large formal libraries in the wiki is suggested for Mizar/MML and Coq/CoRN, based on recently developed precise tracking of mathematical dependencies. We propose to use features of state-of-the-art filesystems to allow real-time cloning and sandboxing of the entire libraries, allowing also to extend the wiki to a true multi-user collaborative area. A number of related issues are discussed.

Objectives: To estimate the economic efficiency of tight blood pressure control, with angiotensin converting enzyme inhibitors or beta blockers, compared with less tight control in hypertensive patients with type 2 diabetes. Design: Cost effectiveness analysis incorporating within trial analysis and estimation of impact on life expectancy through use of the within trial hazards of reaching a defined clinical end point. Use of resources driven by trial protocol and use of resources in standard clinical practice were both considered. Setting: 20 hospital based clinics in England, Scotland, and Northern Ireland. Subjects: 1148 hypertensive patients with type 2 diabetes from UK prospective diabetes study randomised to tight control of blood pressure (n=758) or less tight control (n=390). Main outcome measure: Cost effectiveness ratios based on (a) use of healthcare resources associated with tight control and less tight control and treatment of complications and (b) within trial time free from diabetes related end points, and life years gained. Results: Based on use of resources driven by trial protocol, the incremental cost effectiveness of tight control compared with less tight control was cost saving. Based on use of resources in standard clinical practice, incremental cost per extra year free from end points amounted to £1049 (costs and effects discounted at 6% per year) and £434 (costs discounted at 6% per year and effects not discounted). The incremental cost per life year gained was £720 (costs and effects discounted at 6% per year) and £291 (costs discounted at 6% per year and effects not discounted). Conclusions: Tight control of blood pressure in hypertensive patients with type 2 diabetes substantially reduced the cost of complications, increased the interval without complications and survival, and had a cost effectiveness ratio that compares favourably with many accepted healthcare programmes.

This study examined people's self-presentation motives in unstructured, everyday social interaction as a function of participants' gender similarity to, and general familiarity with, the targets of their self-presentations. Participants maintained a variant of the Rochester Interaction Record for 1 week. For every interaction that lasted 10 min or more, they rated the degree to which they wanted to make each of 4 impressions (likable, competent, ethical, and attractive), how much they thought about the impressions others in the interaction formed of them, and how nervous they felt in the interaction. In general, participants' self-presentational motives were lower in interactions with highly familiar people of their own sex than they were either in interactions with less familiar people of their sex or in interactions with people of the other sex regardless of familiarity. When participants' interactions with only their 3 most familiar interactants were examined, self-presentational concerns decreased with familiarity in same-sex interactions but increased with familiarity in cross-sex interactions.

Contains fulltext : 92216.pdf ( ) (Closed access)

We use density functional theory to quantify finite size and shape effects for gold nanoclusters. We concentrate on the computation of binding energy as a function of bond length for icosahedral and cuboctohedral clusters. We find that the cuboctoheral gold clusters have lower energy for 13 atoms. For 55 atoms we find that the icosahedral gold clusters have lower binding energy. We also introduce a one parameter family of geometries that interpolate between the icosahedral and cuboctohedral clusters that is parametrized by an angle variable. We determine the binding energy dependence on shape as a function of the angle variable for 13 and 55 atom clusters with a minimum at the cuboctohedral point and icosahedral point respectively. We also compute the binding energy for the 147 atom gold nanocluster and show that the binding energy of the icosahedral cluster is lower than the 147 atom cuboctohedral gold cluster. We also compute the binding energy of the $Au_{55}O_2$ molecule with possible applications to catalysis., Comment: 15 pages, 12 figures

4-Hydroxyandrostenedione (4-OHA), a new specific aromatase inhibitor, was used to treat 57 post-menopausal women with advanced breast cancer at a dose of 250 mg by i. m. injection every 2 weeks; 55 women were assessable for response. In all, 18 patients (33%) had objective evidence of a response to treatment, with a median duration of 12 months; the disease stabilised in 8 (14%) patients. Serum oestradiol levels, which were measured weekly in nine of the patients, were found to be suppressed to a mean of between 36% and 51% of pretreatment levels during the first 6 weeks of treatment. Three patients were withdrawn from treatment because of toxicity (pain at injection site, sterile abscess and rash). One patient had an isolated episode of anaphylaxis after 6 months of treatment. In comparison with our previous reports of 4-OHA treatment, a dose of 250 mg given i. m. fortnightly appears to be the optimal dose regimen. The efficacy of the drug seems to be similar to that of tamoxifen and aminoglutethimide.

The exact numerical diagonalization and thermodynamics in an ensemble of small Hubbard clusters in the ground state and finite temperatures reveal intriguing insights into the nascent charge and spin pairings, Bose condensation and ferromagnetism in nanoclusters. The phase diagram off half filling strongly suggests the existence of subsequent transitions from electron pairing into unsaturated and saturated ferromagnetic Mott-Hubbard like insulators, driven by electron repulsion. Rigorous criteria for the existence of quantum critical points in the ground state and corresponding crossovers at finite temperatures are formulated. The phase diagram for 2x4-site clusters illustrates how these features are scaled with cluster size. The phase separation and electron pairing, monitored by a magnetic field and electron doping, surprisingly resemble phase diagrams in the family of doped high Tc cuprates., Comment: 10 pages, 6 figures

Recently, there has been an increased interest in first-principles calculations of the actinides as well as in finding the new materials which display surface magnetism. We predict the existence of a magnetic moment on the uranium (001) surface by performing density functional calculations for a slab geometry in the generalized gradient and local spin density approximations with included spin orbit coupling. The ferromagnetic phase is energetically favored for all geometries. The calculated total magnetic moment, $0.65{\mu_{B}}$, is stable on films of different thickness and it should be observable experimentally., Comment: 4 pages, 4 figures

We use synchrotron x-ray and precision electron diffraction techniques to determine accurately the structure factors of selected reflections that are sensitive to the valence electron distribution in the superconductor MgB2. These values deviate significantly from calculated structure factors using the scattering factors of free atoms, but agree well with our calculated structure factors based on density functional theory. Having experimentally established the reliability of our firstprinciple calculated structure factors, we present electron density maps of the redistribution of the valence electrons that takes place when hypothetical free atoms of Mg and B in MgB2 interact to form the real crystal.

We report a phase I/II study of the indole derivative, zindoxifene, an anti-oestrogen with intrinsic oestrogenic activity. We have treated 28 women with advanced breast cancer of whom 26 had received prior endocrine therapy. Oral zindoxifene doses ranged from 10 to 100 mg daily; doses were escalated in some patients. Twenty-five patients were assessed for response; the remaining three patients completed less than 3 weeks of treatment. There were no objective responses; disease stabilised in seven patients for up to 5 months and progressed in the remaining 18. Five patients (including three treated with tamoxifen) responded to subsequent endocrine therapy. Nausea, which was dose-limiting, affected half of the patients treated with 80 mg daily. Metabolites of zindoxifene were detectable in serum at all doses used, and sex hormone binding globulin (SHBG) levels showed a strong tendency to rise at the higher doses, indicating that zindoxifene is absorbed and has biological activity. We conclude that zindoxifene in the doses used in this study has only marginal therapeutic activity in the treatment of advanced breast cancer.

Assessment of healing of a scaphoid fracture, which may be associated with delayed fusion and nonunion, is a challenging task for the radiologist. Thirty cases of clinically suspected nonunion scaphoid waist fractures with inconclusive plain radiographs were prospectively studied by means of stationary tomography and lateral flexion-extension tomography. The angle between the two scaphoid fragments as seen in extension was measured and compared with the angle as seen in flexion. A difference of 10 degrees or greater between flexion and extension was considered significant. This was noted in 14 of 15 cases of nonunion. Fifteen cases without angle differences were accurately diagnosed as stable. One false-negative case was noted, which on review was attributed to a limited extension view. Flexion-extension tomography is a highly valuable diagnostic modality in evaluating the stability and healing of scaphoid fracture and is superior to conventional (stationary) tomography.

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Cylindrical algebraic decompositions (CADs) are a key tool for solving problems in real algebraic geometry and beyond. We recently presented a new CAD algorithm combining two advances: truth-table invariance, making the CAD invariant with respect to the truth of logical formulae rather than the signs of polynomials; and CAD construction by regular chains technology, where first a complex decomposition is constructed by refining a tree incrementally by constraint. We here consider how best to formulate problems for input to this algorithm. We focus on a choice (not relevant for other CAD algorithms) about the order in which constraints are presented. We develop new heuristics to help make this choice and thus allow the best use of the algorithm in practice. We also consider other choices of problem formulation for CAD, as discussed in CICM 2013, revisiting these in the context of the new algorithm.

The goal of this project is to (i) accumulate annotated informal/formal mathematical corpora suitable for training semi-automated translation between informal and formal mathematics by statistical machine-translation methods, (ii) to develop such methods oriented at the formalization task, and in particular (iii) to combine such methods with learning-assisted automated reasoning that will serve as a strong semantic component. We describe these ideas, the initial set of corpora, and some initial experiments done over them.