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Importance: Ulnar neuropathy at the elbow is the second most frequent entrapment neuropathy, affecting 6% of the population. Surgical criteria are based on a general agreement but remain controversial about which procedure is associated with the best results and the fewest complications. This data can help evaluate the effectiveness of operative techniques in symptomatic cure. Material and Methods: The study analysis included 26 out of 35 patients with 'Ulnar neuropathy at elbow' diagnosis, treated between January 2017- March 2022 at the Department of Neurosciences, University Service of Neurosurgery, University Hospital Center “Mother Theresa”, Tirana, Albania. 9 patients from the time period January-June 2018 were excluded from this study analysis due to lack of access to data. Data sources such as medical records and documentation copies of instrumental examinations were extracted from archives of Statistics Service and Hospital Registers, University Hospital Center “Mother Theresa”, Tirana, Albania. Phone follow-up was applied as well. Results: We report 26 patients analyzed retrospectively (female: male ratio 1:2.71). 29 operated extremities were studied: 26 with Cubital Tunnel Syndrome, of which 2 presented with ipsilateral Carpal Tunnel Syndrome and 1 bilateral; 2 with contralateral Carpal Tunnel Syndrome. There were 11 patients gr. II McGowan and 15 patients gr. III McGowan. There are no positive elbow flexion-extension test cases, indicative of the transposition technique. All patients were clinically evaluated at a distance of 1-3 years post-operatively and 19% presented objective symptoms. Long-term follow-up shows the motor and sensory improvement for gr. II McGowan patients, while gr. III McGowan patients show only sensory and grip improvement, with the persistence of muscular atrophy. The most frequent cause of compression was determined fibrosis and hypertrophy around the Osborne ligament (13/26). Conclusions: Clinical stage of neuropathy is the decisive factor influencing prognosis. Simple decompression in situ is sufficient in most cases. Dynamic intraoperative testing of sulcus competence, to assess (sub)luxation of the ulnar after decompression, determines the final operative technique.

Pinus massoniana L. is an important andi typical ectomycorrhizal dependent tree species in Guizhou. In order to reveal the community structure and driving factors for ectomycorrhizal fungi (ECMF) of P. massoniana in Karst region, Illumina MiSeq high-throughput sequencing was used to study the diversities and community structure characteristics of ECMF in the rhizosphere soil of P. massoniana L. in the three sites of Xugongdian (SY1), Dishuiguanyin (SY2) and Yingtaowan (SY3) in Yuntai Mountain, Guizhou. The ectomycorrhizal fungi belonged to 2 phyla, 5 classes, 11 orders, and 38 genera. At the phylum level, ectomycorrhizal fungi mainly belonged to the Basidiomycota, accounting for 96.20% of all ectomycorrhizal fungi; the rest were Ascomycota fungi, accounting for only 3.8%. At the genus level, Russula, Cortinarius, Suillus, Inocybe, Tricholoma, Tomentella, Sebacina, Scleroderma, Cenococcum were the dominant ectomycorrhizal fungi of P. massoniana . The diversity and richness of ectomycorrhizal fungi communities in the three sites were significantly different. The ectomycorrhizal fungal community structures in SY1 and SY3 were similar, but were quite different from those in SY2. All soil factors explained 97.7% of the differences in the community composition of ECMF, with AP, TN, OM and AK being the main driving factors for the differences in the community composition of ectomycorrhizal fungi in the three sites. Bangladesh J. Bot. 51(4): 913-922, 2022 (December) Special

Searchable encryption (SE) technology allows users to use keywords to retrieve encrypted data and ensure that useful plaintext information of encrypted data will not be disclosed. For a secure SE scheme, if it is able to meet the multi-trapdoor privacy (MTP), the security will be improved compare with the traditional SE scheme. However, there are few searchable encryption schemes that can meet the requirement of MTP. In addition, many existing schemes ignore the need of multi keyword search, and both sides of communication use the same cryptosystem and cryptographic parameters, which leads to the problem of low search efficiency and practicability. Therefore, we propose a heterogeneous SE scheme that supports multi-keyword search, provides MTP and allows both sides of communication to be worked in different cryptosystems with different cryptographic parameters. With the use of the random oracle model (ROM), we demonstrate the security of the proposed scheme, and we show the excellent performance of the proposed scheme at the end of the article.

BACKGROUND: The coronavirus infection of 2019 (COVID-19) produced an incontestable impact on the mental health of people around the world. This impact is conditioned by a complex interrelation of social, cultural, economic and COVID-19-associated factors. However, insufficient data on comparison of parameters of mental health of the population in different countries limits our understanding of these interrelations. AIM: To evaluate and compare the frequency of mental health disorders (general problems and problems related to COVID-19) and their correlations in four countries: Albania, India, Iran and Nigeria. MATERIALS AND METHODS: In this study, the problems of mental health of the population of four countries (Albania, India, Iran and Nigeria) were investigated. The participants were selected in the period from July 07, 2020 to November 13, 2020. The study used a cross-check anonymous online questioning to assess the degree of depression, anxiety and insomnia, which included Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder 7 (GAD-7) questionnaire and Insomnia Severity Index (ISI). To assess the mental health problems associated with COVID-19, the survey included Corona Anxiety Scale (CAS), Obsession with COVID-19 Scale (OCS) and Fear of COVID-19 Scale (FCV-19S). To analyze the data, ꭓ2, KruskalWallis tests and multiple linear regression were used. RESULTS: In general, the prevalence of general anxiety, depression, insomnia and COVID-19-associated anxiety, was higher among the Iranian population compared to the other three countries. Risk factors for increased anxiety about the new coronavirus infection were fear, depression, trouble and age; however, these factors were different in the four studied countries. The parameter was highest (47%) in the Albanian population and lowest (20%) in India. CONCLUSIONS: This study shows different prevalence of psychological health disorders during the ongoing pandemics, including problems associated with COVID-19, in different countries. Therefore, healthcare policy and measures adopted in different countries, should be adapted to specific needs of the country rather than be based on the universal global responsive measures.

In the context of continued global climate change, the intensity and frequency of droughts have increased to varying degrees in many places. Due to the complexity of drought events, the mechanisms by which trees respond to drought are not well understood. In this study, we analyzed the growth trends of Qinghai spruce (Picea crassifolia) at different elevations in the western part of Qilian Mountains and the dynamic response to climate change. We also compared the differences in radial growth of trees at different elevations in response to drought events in the growing and non-growing seasons based on resistance (Rt), recovery (Rc), and resilience (Rs). The results showed that (1) trees at all three elevations were limited by drought stress and the lower the elevation the more sensitive the trees were to drought. (2) The response of middle- and low-elevation trees to the standardized precipitation evaporation index in June of that year was stable. (3) Growing season drought limits radial growth of trees more than non-growing season drought, and Rt is smaller and Rc is larger at low elevations. With increasing drought severity, trees at all three elevations exhibited a trend of decreasing Rt and Rs and increasing Rc. (4) There were significant differences in the growth trends of trees at the three elevations. Therefore, we should continuously pay attention to the dynamics of the forest ecosystem in the western part of Qilian Mountains and take improved measures to cope with the adverse effects of drought on Qinghai spruce.

Introduction; Epilepsy is one of the most common neurological chronic disorders, with an estimated prevalence of 0. 5 – 1%. Partial focal epilepsy (PE) is one of the most common types of epilepsies that originates from a relatively limited number of neurons, whose malfunction generates epileptic attacks. Partial focal epilepsies make up 60% of the whole spectrum of epilepsies. Recent studies show that 25% of patient who suffer from PE show a resistance against medication. The duration of symptoms on the one hand and AED treatment on the other hand cause the cognitive dysfunctions in the patients suffering from epileptic seizures, especially children, to suffer progressive damage. Patients suffering from epilepsy have a cost that at the moment is difficult to calculate accurately, but it is still very high. Mesial Temporal lobe seizures are the most common form of partial epileptic seizures originating in the temporal lobe, and they are frequently resistant to anti-epileptic drug treatment. Materials and Methods, At Neurosurgical Department, University Hospital “Mother Theresa”, since 2013 there is a team consisting of different medical specialists, for the study and selection of candidates, who can benefit from surgery. At the same time, since many years now in neurological department there is already a successful tradition in the medicament treatment of epilepsy. The team of medical doctors in our Department, which makes the treatment of these diseases by means of surgery, is made up of: neuro-epileptologist, radiologists, neurologists, psychologists and neurosurgeons. During the period, from 2013 until the year 2021, 35 patients have undergone an operation. All the patients were considered, based on protocols, as pharmacoresistant. Conclusions; The post-surgical results were 80% of the patient’s seizure free and without need to use any antiepileptic treatment, meaning Engel 1. 15% of the patients were seizure free but with the need of antiepileptic treatment and meaning Engel 2 and 5% of patients were not able to be cured by achieving only a modification of the semiology of the crisis and frequency, meaning Engel 3. Anterior temporal lobectomy in majority of the cases is the best surgical treatment of drug-resistant HS-TLE and long-term seizure free patients in this group have been reported about 70% (62-83%).

The subject of the paper refers to the research on beekeepers’ perceptions of environmental threats to beekeeping in the Western Balkan region. The following environmental threats were supposed to be the most pronounced: cutting of melliferous perennial plants and clearing of forests, urbanisation and environmental pollution, use of pesticides in agricultural production, pests and agents of bees’ diseases, climate changes. The aim of the research was to find out how beekeepers perceived these threats, to determine the presence of the threats and to define their intensity as well as their mutual relationship. For the purpose of this research, the authors created a structured questionnaire which was filled in by randomly selected beekeepers living in the Western Balkans. The research results show that most beekeepers in the studied area evaluated the assumed threats as strong to very strong, while the greatest percentage of beekeepers believes that climate change represents the greatest threat to beekeeping in the region. All assumed environmental threats show the same tendency, while they have the most serious effect on large apiaries with more than 150 bee colonies, located in lowland areas up to 200 meters above sea level with intensive farming. Findings of this research are important in order to adapt the current beekeeping practice in the region to more sustainable solutions, through improvement of the existing beekeeping legislation and advisory services.

The most common primary cardiac tumors in adults are atrial myxomas, with adolescent-onset being uncommon. In this case report, a 15-year-old female was hospitalized with cerebrovascular embolism and later diagnosed with a left atrial myxoma. She had previously shown signs of distal vascular micro thrombosis, including recurring bilateral lower extremity rash, which are crucial for the early diagnosis and differential diagnosis of atrial mucinous neoplasm. We reviewed the various clinical symptoms and diagnostic approaches to identify left atrial mucinous neoplasm. This patient also had a combination of endocrine-related diseases. We reviewed the diagnostic approach for the Carney Complex (CNC) and discussed the role of thyroid disease in diagnosing CNC.

Tourism expenditures are an important indicator for measuring the impact of tourism on a destination. Information taken from the micro data of tourism expenditures, together with other socio-demographic characteristics of visitors, provides important data on the tourist demand for a destination. Visitor costs in combination with other variables can be used to profile the demand for tourist goods and services in the destination area. In this paper, the daily expenses of visitors in the Gjirokastra district of Albania are analysed. The Gjirokastra district is one of the more preferred regions and attracts a considerable number of domestic and foreign visitors, because it offers a diversity tourist attractions and services. For the purposes of this study, a survey of 200 visitors was conducted. The survey results were analysed with descriptive statistics via a cluster analysis. The survey provides detailed data on the daily expenses of visitors, divided into six main categories of a typical travel budget. Through the use of data mining cluster analysis, we identified and analysed the tourists’ daily expenses based on the purpose of their visit to the area of Gjirokaster.

These files contain the simulation output used to generate the output figure results in the paper. Each folder corresponds to a figure, contains the corresponding output, and contains the code used to generate the figures.

Background; Pain at the surgical site is an important concern, especially in locations of main joints which may resolve important limitations of movement. Materials and Methods; We present the case of painful dysesthesia after knee surgery for traumatic meniscal rupture in a young lady. She presented with painful dysesthesia, limitation of knee flexion, and severe pain in light touch and pressure on the mid-patellar area of the left knee. Tinel’s sign at the site of surgical scar, dysesthetic area (abnormal sensation) corresponded with the medial reticular nerve at surgical exploration under a microscope. Results; Microsurgical exploration of the three nerves of medial subcutaneous nerves revealed the branch stack in the scar. The distal end was internalized subfascial inside the muscle fibers of the medial vastus of quadriceps femoris muscle according to Dellon. The other two were released from adherences and found to be in anatomical continuity were left in place. Immediate resolution of dysesthesia was referred by the patient and the amplitude of motion was complete at one-month postoperative control. She remains pain-free 4 months from surgery and the area of dysesthesia remains anesthetic at the center. Conclusions; Surgical identification and rerouting of the distal end of sensitive nerves is an efficient treatment after peripheral nerve injury.

The underlying mechanisms of cerebral ischemia/reperfusion (I/R) injury are unclear. Within this study, we aimed to explore whether p53 inhibition exerts protective effects via the p53/PRAS40/mTOR pathway after stroke and its potential mechanism. Both an in vitro oxygen-glucose deprivation (OGD) model with a primary neuronal culture and in vivo stroke models (dMCAO or MCAO) were used. We found that the infarction size, neuronal apoptosis, and autophagy were less severe in p53 KO mice and p53 KO neurons after cerebral I/R or OGD/R injury. By activating the mTOR pathway, p53 knockdown alleviated cerebral I/R injury both in vitro and in vivo. When PRAS40 was knocked out, the regulatory effects of p53 overexpression or knockdown against stroke disappeared. PRAS40 knockdown could inhibit the activities of the mTOR pathway; moreover, neuronal autophagy and apoptosis were exacerbated by PRAS40 knockdown. To sum up, in this study, we showed p53 inhibition protects against neuronal I/R injury after stroke via the p53/PRAS40/mTOR pathway, which is a novel and pivotal cerebral ischemic injury signaling pathway. The induction of neuronal autophagy and apoptosis by the p53/PRAS40/mTOR pathway may be the potential mechanism of this protective effect.

Introduction and Objectives Approximately 30% of patients meeting severe injury criteria are never transferred to lead trauma centers (LTCs). The reasons for this gap are not fully understood but involve both system-level factors and individual decision-making. We used a method called discrete choice modeling (DCM) to evaluate which clinical and demographic patient factors might make emergency physicians more likely to initiate transfers to LTCs. Methods An email survey was distributed to physicians working in emergency departments (EDs) in Ontario. The relative importance of clinical and demographic patient attributes as drivers for transfer was evaluated using DCM. Simulated patient cases were created using a random generator to combine attributes. Each respondent was presented with 36 different patients in sets of three and asked if they would transfer each patient to an LTC. The relative importance of each driver was then compared across physician characteristics. Results One hundred and fifty three emergency physicians completed the survey. The drivers for transfer, expressed as utility scores, were derangements in hemodynamics (22), CNS/head injuries (19), pelvic fractures (11), chest injuries (10), comorbidities (9), abdominal injuries (8), extremity injuries (7), mechanism of injury (7), age (5), and gender (2). Drivers for patient transfer did not differ based on physician experience or type of training. Conclusion In this DCM study, the clinical and demographic factors most likely to make emergency physicians consider patient transfers to LTCs were patient hemodynamic derangements and CNS/head injuries. Overall, these drivers did not differ by physician experience or training. An understanding of such patient-level drivers for transfers to LTCs may improve the implementation of evidence-based interfacility transfer criteria.

Past studies have established mesophyll diffusion conductance to CO2 (gm ) as a variable and significant limitation to plant photosynthesis under steady-state conditions. However, the role of gm in influencing photosynthesis (A) during the transient period of light induction is largely unknown. We combined gas exchange measurements with laser-enabled carbon isotope discrimination measurements to assess gm during photosynthetic induction, using Arabidopsis as the measurement species. Our measurements revealed three key findings: (1) we found that the rate at which gm approached steady state during induction was not necessarily faster than the induction rate of the carboxylation process, contradictory to what has been suggested in previous studies; (2) gm displayed a strong and consistent coordination with A under both induction and steady-state settings, hinting that the mechanism driving gm -A coupling does not require physiological stability as a prerequisite; and (3) photosynthetic limitation analysis of our data revealed that when integrated over the entire induction period, the relative limitation of A imposed by gm can be as high as > 35%. The present study provides the first demonstration of the important role of gm in limiting CO2 assimilation during photosynthetic induction, thereby pointing to a need for more research attention to be devoted to gm in future induction studies.

The reduced chromite ore processing residue (rCOPR) deposited in environments is susceptible to surrounding factors and causes reoccurrence of Cr(VI). However, the impact of natural sunlight on the stability of rCOPR is still unexplored. Herein, we investigated the dissolution and transformation behaviors of Cr(III)-Fe(III) hydroxide, a typical Cr(III)-containing component in rCOPR, under visible light. At acidic conditions, the release rate of Cr(III) under illumination markedly increased, up to 7 times higher than that in the dark, yet no Cr(VI) was produced. While at basic conditions, only Cr(VI) was obtained by photo-oxidation, with an oxidation rate of ∼7 times higher than that by δ-MnO

Parkinson’s disease (PD) is a complex neurodegenerative disease, manifested by the progressive functional impairment of the midbrain nigral dopaminergic neurons. Due to the unclear underlying pathogenesis, disease-modifying drugs for PD remain elusive. In Asia, such as in China and India, herbal medicines have been used in the treatment of neurodegenerative disease for thousands of years, which recently attracted considerable attention because of the development of curative drugs for PD. In this review, we first summarized the pathogenic factors of PD including protein aggregation, mitochondrial dysfunction, ion accumulation, neuroinflammation, and oxidative stress, and the related recent advances. Secondly, we summarized 32 Chinese herbal medicines (belonging to 24 genera, such as Acanthopanax, Alpinia, and Astragalus), 22 Chinese traditional herbal formulations, and 3 Indian herbal medicines, of which the ethanol/water extraction or main bioactive compounds have been extensively investigated on PD models both in vitro and in vivo. We elaborately provided pictures of the representative herbs and the structural formula of the bioactive components (such as leutheroside B and astragaloside IV) of the herbal medicines. Also, we specified the potential targets of the bioactive compounds or extractions of herbs in view of the signaling pathways such as PI3K, NF-κB, and AMPK which are implicated in oxidative and inflammatory stress in neurons. We consider that this knowledge of herbal medicines or their bioactive components can be favorable for the development of disease-modifying drugs for PD.

The Human Genome Project marked a major milestone in the scientific community as it unravelled the ~3 billion bases that are central to crucial aspects of human life. Despite this achievement, it only scratched the surface of understanding how each nucleotide matters, both individually and as part of a larger unit. Beyond the coding genome, which comprises only ~2% of the whole genome, scientists have realized that large portions of the genome, not known to code for any protein, were crucial for regulating the coding genes. These large portions of the genome comprise the 'non-coding genome'. The history of gene regulation mediated by proteins that bind to the regulatory non-coding genome dates back many decades to the 1960s. However, the original definition of 'enhancers' was first used in the early 1980s. In this Review, we summarize benchmark studies that have mapped the role of cardiac enhancers in disease and development. We highlight instances in which enhancer-localized genetic variants explain the missing link to cardiac pathogenesis. Finally, we inspire readers to consider the next phase of exploring enhancer-based gene therapy for cardiovascular disease.

Epidermal growth factor receptor ( EGFR) mutations and anaplastic lymphoma kinase ( ALK) rearrangements are considered mutually exclusive in non-small cell lung cancer (NSCLC), especially in lung adenocarcinoma (LUAC). However, sporadic cases harboring concomitant EGFR and ALK alterations have been increasingly reported. There is no consensus opinion regarding the treatment of patients positive for both molecular alterations. NSCLC with EGFR/ ALK coalterations should be separated into two subtypes: unifocal and multifocal LUAC. Here, we present an overview of the available literature regarding this rare group of patients to provide useful suggestions for therapeutic strategies.

The generation and control of double hysteresis loops in ferroelectrics are of great significance for understanding the polarization reversal and application of energy storage. For Sm/Mn ions co-doped 0.70PMN-0.30PT ceramics, results indicate that when Sm-doping content is 2.5 mol%, the Mn doping content is higher than 2.5 mol% and the frequency of the electric field is higher than 5 Hz, double hysteresis loops can be obtained. Low-frequency measurement can transform the double hysteresis loops into normal hysteresis loops. This phenomenon is analyzed by the difference in polarization reversal kinetics between spontaneous polarization and defect polarization.

The San Francisco Bay Area has experienced a rapid rise in homelessness over the past decade. There is a critical need for quantitative analysis to help determine how to increase the amount of housing to meet the needs of people experiencing homelessness. Noting that the shortage of housing available through the homelessness response system can be modeled as a queue, we propose a discrete-event simulation to model the long-term flow of people through the homelessness response system. The model takes as input the rate of additional housing and shelter available each year and delivers as output the predicted number of people housed, sheltered, or unsheltered in the system. We worked with a team of stakeholders to analyze the data and processes for Alameda County in California and use this information to build and calibrate two simulation models. One model looks at aggregate need for housing, while the other differentiates the housing needs of the population into eight different types. The model suggests that a large investment in permanent housing and an initial ramp up of shelter is needed to solve unsheltered homelessness and accommodate future inflow to the system.

Objectives: The global crisis of COVID-19 and its consequential strict public health measures placed around the world have impacted mental health. New scales and tools have been developed to measure these mental health effects. This narrative review assesses the psychometric properties of these scales and tools and methodological aspects of their development. Methods: PubMed, PubMed Central, and Google Scholar were searched for articles published from 15 May 2020 to 15 August 2020. This search used three groups of terms (“tool” OR “scale” AND “mental” OR “psychological”; AND “COVID-19” OR “coronavirus”). The identified scales were further evaluated for their psychometric properties and methodological aspects of their development. Results: Though the studies developing these scales ( n = 12) have demonstrated their robust psychometric properties, some methodological concerns are noteworthy. Most of the scales were validated using internet-based surveys, and detailed descriptions of the mode of administration, sampling process, response rates, and augmentation strategies were missing. Conclusions: The heterogeneous and inadequate reporting of methods adopted to evaluate the psychometric properties of the identified scales can limit their utility in clinical and research settings. We suggest developing guidelines and checklists to improve the design and testing, and result in reporting of online-administered scales to assess the mental health effects of the COVID-19 pandemic.

PurposeTo provide a comprehensive systematic review of entrepreneurship in the context of emerging markets (EMs). The area of research is topical considering the rise of EMs on the global scene and the importance of entrepreneurship in the development of EMs.Design/methodology/approachThe paper utilizes scientometrics to provide a systematic review of the emerging field of entrepreneurship in EMs (EEMs). The entire Web of Science database was searched, and 2,568 scholarly outputs were extracted and analyzed as a result. The review further compares the EEMs research to the mainstream entrepreneurship research based on the top trending and high impact themes, demonstrates which countries published and are studied in the EEMs scholarship, and finally, it provides a proportion of empirical research done on EEMs to highlight methods utilized in the existing research.FindingsThe scientometric review reveals three broad domains of the EEMs scholarship–(1) Entrepreneurship in EMs and its implications; (2) MNEs, institutional environments, and FDI; and (3) Strategy, innovation and performance. The findings demonstrate that EEMs' scholarship primarily discusses environments within which EEMs takes place, the implications of EEMs, strategy and performance of EEMs (macro and meso-levels), thus highlighting the need for micro-level (individual-based) analysis of EEMs. Approximately, a third of the EEMs research is of empirical nature, more should be done especially in quantitative studies to develop this field further.Originality/valueThis research is unique in providing the largest review of EEMs scholarship. It divides the entire scholarship into three inter-related research streams and identifies future research directions in this immensely important field of research.

In wireless body area network (WBAN), the WBAN sensors usually transmit encrypted data for the sake of security. But because of this, finding and getting the required data quickly becomes a challenge. Thus, many scholars have proposed searchable encryption (SE) schemes. Regrettably, many proposed SE schemes are not resistant to inside keyword guessing attack (IKGA), and most schemes are not suited for cross-domain communication in WBAN because they use single cryptosystem and the same cryptographic system parameters. To address the aforementioned issues, we put forward a new SE scheme for WBAN based on the public key cryptosystem in this paper. Our scheme allows WBAN sensors in certificateless public key cryptography (CLC) and receivers in public key infrastructure (PKI) environment use different cryptographic system parameters to realize cross-domain heterogeneous communication. At the same time, our scheme can effectively resist IKGA. Compared to the five existing schemes, the total computation cost of our scheme reduced by at least 59.99%.

In wireless body area network (WBAN), the WBAN sensors usually transmit encrypted data for the sake of security. But because of this, finding and getting the required data quickly becomes a challenge. Thus, many scholars have proposed searchable encryption (SE) schemes. Regrettably, many proposed SE schemes are not resistant to inside keyword guessing attack (IKGA), and most schemes are not suited for cross-domain communication in WBAN because they use single cryptosystem and the same cryptographic system parameters. To address the aforementioned issues, we put forward a new SE scheme for WBAN based on the public key cryptosystem in this paper. Our scheme allows WBAN sensors in certificateless public key cryptography (CLC) and receivers in public key infrastructure (PKI) environment use different cryptographic system parameters to realize cross-domain heterogeneous communication. At the same time, our scheme can effectively resist IKGA. Compared to the five existing schemes, the total computation cost of our scheme reduced by at least 59.99%.

A new myxobolid species, Myxobolus zaikae n. sp., was found in the connective tissue near the kidney and liver blood vessels of the common roach Rutilus rutilus, while fish myxosporean fauna were being investigated in Lake Baikal, Russia. The parasites were studied on the basis of spore morphology as well as with histological and molecular methods. Mature spores of M. zaikae n. sp. are round or ellipsoidal in the frontal view and lemon-shaped in the lateral view, measuring 11.37 ± 0.11 µm (10.2-14.0 µm) in length, 10.29 ± 0.10 µm (9.6-11.0 µm) in width, and 6.3 ± 0.08 µm (5.8-7.1 µm) in thickness (mean ± SD; n = 50). Polar capsules are equal and pyriform, measuring 4.5 ± 0.07 µm (3.4-5.2 µm) in length and 2.9 ± 0.03 µm (2.6-3.3 µm) in width. Polar capsules contained polar filaments coiled with 5 to 6 turns. Phylogenetic analysis showed that this newly described species clusters with other myxobolid species infecting the connective tissue of different organs from Palearctic cyprinid fish.

Neurogenic Thoracic Outlet Syndrome (NTOS) is a rare, but controversial syndrome in relation to its diagnosis, treatment modality, and approaches in case of surgical treatment. In the English literature, there are sparse studies dealing with these aspects. We conducted a PubMed 2000-2017 literature review and found a total of 3953 cases reported with NTOS. The clinical characteristics, etiology, electrophysiological and radiological work-up and treatment options were reviewed and reported. It seems that, as far as surgical indication criteria are concerned, there is a consensus for NTOS in its motor deficit stage and its techniques are generally well established. This review showed that differential diagnosis, radiological, and electrophysiological criteria for correct diagnosis of NTOS are not controversial. However, surgical indications and types of approaches and techniques reflect the surgeon’s affiliation with specialties dealing with NTOS (vascular, plastic, hand, orthopedic or neurosurgeons), and the surgeon’s experience with this specific and rare syndrome.

A systems perspective of an emergent field such as Industry 4.0 requires combining and analysing the entire multidisciplinary scholarship under one map. Recent developments in scientometric analysis allow researchers to carry out complex bibliometric analyses coupled with an unstructured ontological discovery made available through thematic and ensuing semantic analyses to gain a holistic outlook on the ecosystem of Industry 4.0. The state‐of‐the‐art review of the entire scholarship of Industry 4.0 demonstrates three broad clusters—the implications of automation on industry, the integration of technologies and technological advancements driving the Fourth Industrial Revolution. The scholarship output is, for the first time, compared with the leading industrial and policymaking institutional reports to highlight similarities and discrepancies. This allows to propose a previously unavailable definition of Industry 4.0, which is much needed to progress the research further. The three highly discrepant areas between academic literature and industry insights include lack of research into return on investment, lack of research involving policymaking, and the implications of technological development on the workforce, firms and countries. It is imperative to drive research into the existent, as well as the highlighted, themes in advancing the knowledge and aligning the academic scholarship with the interests of practitioners.

Aquatic hypoxia is a frequent event and a complex set of physiological and biochemical alterations are employed to cope with this environmental stress in fish. This study aimed at evaluating the protective effects of Sargassum horneri on hypoxia stress in black sea bream Acanthopagrus schlegelii. Four hundred and eighty fingerlings with approximate mean body weight of 12.0 ± 0.1 g were randomly distributed into four experimental groups in triplicate. Each group was stocked with 40 fish and fed with isonitrogenous (42% crude protein) and isolipidic (12% crude lipid) experimental diets containing either 0% (control), 3%, 6%, or 9% S. horneri in the feed. At the end of 8 weeks of experimental feeding, fish were exposed to hypoxia (dissolved oxygen 2.5 mg L−1) conditions for 12 h and subsequent recovery to normoxia (dissolved oxygen 7.2 mg L−1). Fish samples were collected after hypoxia stress at 0, 6, 12 h, and 12 h recovery to normoxia, respectively. Hypoxia stress caused a significant increase in the serum concentrations of cortisol, glucose, and lactate at 6 h after hypoxia, as well as the activities of hepatic superoxide dismutase (SOD) and MDA content at 12 h after hypoxia compared with 0 h after hypoxia. Moreover, the fish exhibited a significantly higher level in the mRNA expressions of hepatic Cu/Zn-SOD, HSP70, and HSP90 at 12 h after hypoxia. However, dietary S. horneri supplementation could significantly improve antioxidant capacity and resistance against hypoxia stress, particularly in the 6% S. horneri group. Therefore, the optimal dietary S. horneri level based on increasing the resistance of hypoxia for juvenile black sea bream in the present study was estimated to be approximately 6% dry diet.

The dissimilar welding of Al–Zn–Mg alloy (7005) plates and Al–Mg alloy (5083) rods was conducted using the inertia friction welding process. The effect of rotational speed during welding on the microstructure and mechanical properties of the joints was then investigated. The results indicate that under lower rotational speeds, a transition layer was formed at the interface that reduced the tensile strength of the joint. However, dynamic recrystallization occurred in the region near the interface resulting in excellent grain refinement and good metallurgical bonding. The tensile strength of the joints increased with increasing rotational speed due to the extrusion of the transition layer under higher rotational speeds. A maximum tensile strength of 311.4 MPa, approximately 88% of the 5083 base metal tensile strength, was achieved using a rotational speed of 3000 rpm. All tensile specimens manufactured at lower rotational speeds failed along the interface between base metal and weld. However, the peripheral zone of the tensile specimens manufactured at 3000 rpm fractured in the thermo-mechanically affected zone of the 5083 alloy via a quasi-cleavage fracturing mode. The results of this study are expected to be useful in improving the quality of dissimilar aluminum alloy welds.

In Albania, the region of Kelmend is best known and valued for the Mishavinë cheese which is produced there. In this paper we analyse the farmers’ experience of origin-based cheese and being part of the Slow Food Presidium of products in Albania. The role of local producers is fundamental not only in continuing tradition but also for the social and economic impact it has on farmers in the area. The survey in this study was conducted with face-to-face interviews with producers of Mishavinë cheese. The type of survey used was a semi-closed questionnaire. A descriptive analysis was conducted to evaluate the main problems facing the local producers and their collaboration among the relevant stakeholders. As Mishavinë is part of Slow Food the Ark of Taste project, it has a great opportunity to bring producers and consumers together with the aim of regenerating this lost tradition.

We consider the process of forming the iconic system of atlas mapping of the Baikal region. More than twenty atlases were created for the territory of the Baikal region and published. Fifteen of these were selected by us for their general cartosemiotic study. We review the results of the analysis of the information-modular structure of atlases on the example of the map index in these atlases. It is shown that the number of information-semiotic modules in each atlas can vary and depends on its subject and purpose. The subject, structure and purpose of atlases are the cause of their complex and flexible modular-thematic semiotic structure. The analysis of the internal semiotic structure of atlases was carried out from the perspective of a single system of classification of conventional signs and graphic display methods on the example of three atlases: Atlas of Transbaikalia, Atlas of the Baikal Basin and the new atlas “Baikal region: society and nature”. The information and semiotic modules of the new atlas are formed according to the macrostructure of its thematic content, taking into account territorial levels and specific substantive thematic positions of mapping. When creating this atlas, we used effective methods of semiotic modeling and a certain balance and variety of applied syntactic constructions of cartographic signs. The atlas is being prepared for a printing publication as a work of a new kind, integrating modern information about the impact of socio-economic processes on the natural environment. The balance and diversity in the combination of various types, classes, groups and types of syntactic constructions of cartographic signs revealed during semiotic analysis of atlases of the Baikal region shows a high scientific level of map compilation and works on the general semiotic design of the publication of most atlases of the Baikal region.

Myxobolus talievi Dogiel, 1957 was originally described from the eyes, skeletal muscles and body cavity of endemic cottoid fish from Lake Baikal. In the present study, we supply new information on the myxospore morphology and histopathology of M. talievi; furthermore, we complete the original species description by Dogiel and Bogolepova (1957) with 18S ribosomal DNA (rDNA) sequence data. Histopathological analysis showed that the plasmodium was encapsulated by a thin layer of connective tissue and located in the intermuscular connective tissue among muscle cells. No inflammation was observed. Phylogenetic analysis revealed that M. talievi clustered with Myxobolus sp. 2 (NCBI Acc. No. U13830), an unidentified Myxobolus species from cottoid fish studied by Smothers et al. (1994), and located in the sister clade of Myxobolus spp. developing spores in the nerves of salmonids.