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2. Defective cortex glia plasma membrane structure underlies light-induced epilepsy in

Author

Govind, Kunduri, Daniel, Turner-Evans, Yutaka, Konya, Yoshihiro, Izumi, Kunio, Nagashima, Stephen, Lockett, Joost, Holthuis, Takeshi, Bamba, Usha, Acharya, and Jairaj K, Acharya

Subjects
Cerebral Cortex, Male, Neurons, Cell Membrane, Membrane Proteins, Transferases (Other Substituted Phosphate Groups), Nerve Tissue Proteins, Epilepsy, Reflex, Sphingomyelins, Animals, Genetically Modified, Disease Models, Animal, Drosophila melanogaster, Mutation, Animals, Drosophila Proteins, Humans, Neuroglia
Abstract

Seizures induced by visual stimulation (photosensitive epilepsy; PSE) represent a common type of epilepsy in humans, but the molecular mechanisms and genetic drivers underlying PSE remain unknown, and no good genetic animal models have been identified as yet. Here, we show an animal model of PSE, in

Published
2018

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