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14 results on '"D Andrea, F."'

1. Open rhinoplasty by paramarginal incision

Author

D Andrea, F., Sergio brongo, Ferraro, G. A., D'Andrea, Francesco, Brongo, S, Ferraro, G., and Ferraro, Giuseppe

Abstract

One of the major handicaps in rhinoplastic surgery has always been the lack of a wide view of the nose's osseocartilaginous structures. In the past, this problem was solved by an open approach, following incision of the columella. This method is not, however, universally accepted since it causes an additional external scar. The open rhinoplasty technique without incision of the columella was adopted in fourteen cases, selected according to type of defect and the need to obtain a wider view of the nose's internal structures. Satisfactory cosmetic and functional results were achieved. No major complications occurred and in all cases the only problem arising was transitory edema in the tip. The authors maintain that the advantage of open rhinoplasty, with wide exposure of the operating area and a more direct view of the alar cartilages and quadrangular cartilage, is that it makes correction of tip and nasal septum defects easier and more precise. This technique also avoids discomfort and the danger of a scar on the columella.

Published
1998

2. The ubiquitin-proteasome system and inflammatory activity in diabetic atherosclerotic plaques: Effects of rosiglitazone treatment

Author

Marfella, R., michele d'amico, Esposito, K., Baldi, A., Di Filippo, C., Siniscalchi, M., Sasso, F. C., Portoghese, M., Cirillo, F., Cacciapuoti, F., Carbonara, O., Crescenzi, B., Baldi, F., Ceriello, A., Nicoletti, G. F., D Andrea, F., Verza, M., Coppola, L., Rossi, F., Giugliano, D., Marfella, R, D'Amico, Michele, Esposito, Katherine, Baldi, Alfonso, DI FILIPPO, Clara, Siniscalchi, M, Sasso, Ferdinando Carlo, Portoghese, M, Cirillo, F, Cacciapuoti, Federico, Carbonara, O, Crescenzi, B, Baldi, F, Ceriello, A, Nicoletti, Giovanni Francesco, D'Andrea, Francesco, Verza, M, Coppola, L, Rossi, Francesco, Giugliano, Dario, Raffaele, M, D'Amico, M, Esposito, K, Baldi, A, DI FILIPPO, C, Sasso, F, Cacciapuoti, F, Nicoletti, Gf, Rossi, F, and Giugliano, D.

Subjects
Ubiquitin-Proteasome System, inflammation, diabete, Atherosclerotic Plaque, Rosiglitazone Treatment
Abstract

The role of ubiquitin-proteasome system in the accelerated atherosclerotic progression of diabetic patients is unclear. We evaluated ubiquitin-proteasome activity in carotid plaques of asymptomatic diabetic and nondiabetic patients, as well as the effect of rosiglitazone, a peroxisome proliferator-activated receptor (PPAR)-γ activator, in diabetic plaques. Plaques were obtained from 46 type 2 diabetic and 30 nondiabetic patients undergoing carotid endarterectomy. Diabetic patients received 8 mg rosiglitazone (n = 23) or placebo (n = 23) for 4 months before scheduled endarterectomy. Plaques were analyzed for macrophages (CD68), T-cells (CD3), inflammatory cells (HLA-DR), ubiquitin, proteasome 20S activity, nuclear factor (NF)-κB, inhibitor of κB (IκB)-β, tumor necrosis factor (TNF)-α, nitrotyrosine, matrix metalloproteinase (MMP)-9, and collagen content (immunohistochemistry and enzyme-linked immunosorbent assay). Compared with nondiabetic plaques, diabetic plaques had more macrophages, T-cells, and HLA-DR cells (P < 0.001); more ubiquitin, proteasome 20S activity (TNF-α), and NF-κB (P < 0.001); and more markers of oxidative stress (nitrotyrosine and O 2- production) and MMP-9 (P < 0.01), along with a lesser collagen content and IκB-β levels (P < 0.001). Compared with placebo-treated plaques, rosiglitazone-treated diabetic plaques presented less inflammatory cells (P < 0.01); less ubiquitin, proteasome 20S, TNF-α, and NF-κB (P < 0.01); less nitrotyrosine and superoxide anion production (P < 0.01); and greater collagen content (P < 0.01), indicating a more stable plaque phenotype. Similar findings were obtained in circulating monocytes obtained from the two groups of diabetic patients and cultured in the presence or absence of rosiglitazone (7.0 μmol/l). Ubiquitin-proteasome over-activity is associated with enhanced inflammatory reaction and NF-κB expression in diabetic plaques. The inhibition of ubiquitin-proteasome activity in atherosclerotic lesions of diabetic patients by rosiglitazone is associated with morphological and compositional characteristics of a potential stable plaque phenotype, possibly by downregulating NF-κB-mediated inflammatory pathways. © 2006 by the American Diabetes Association.

6. [Obesity and Eating Disorders. Indications for the different levels of care. An Italian Expert Consensus Document]. | Documento di Consensus. Obesità e Disturbi dell'Alimentazione Indicazioni per i diversi livelli di trattamento

Author

Donini, L. M., Cuzzolaro, M., Spera, G., Badiali, M., Basso, N., Bollea, M. R., Bosello, O., Brunani, A., Busetto, L., Cairella, G., Cannella, C., Capodaglio, P., Carbonelli, M. G., Castellaneta, E., Castra, R., Clini, E., Contaldo, F., Dalla Ragione, L., Dalle Grave, R., D Andrea, F., Del Balzo, V., Cristofaro, P., Di Flaviano, E., Fassino, S., Ferro, A. M., Forestieri, P., Franzoni, E., Gentile, M. G., Giustini, A., Jacoangeli, F., Lubrano, C., Lucchin, L., Manara, F., Marangi, G., Marcelli, M., Marchesini, G., Marri, G., Marrocco, W., Melchionda, N., Mezzani, B., Migliaccio, P., Muratori, F., Nizzoli, U., Ostuzzi, R., Panzolato, G., Pasanisi, F., Persichetti, P., Petroni, M. L., Pontieri, V., Prosperi, E., Renna, C., Rovera, G., Santini, F., Saraceni, V., Savina, C., Scuderi, N., Silecchia, G., Strollo, F., Todisco, P., Tubili, C., Ugolini, G., and Mauro ZAMBONI

8. Manifesto of the critical issues in preventive and clinical nutrition: The first ten Italian challenges (2015-2018),Manifesto delle criticità in Nutrizione clinica e preventiva: Le prime dieci sfide Italiane (2015-2018)

Author

Lucchin, L., Fusco, M. A., Caretto, A., Alessandrini, L., Facchin, N., Grossi, E., Dalle Grave, R., Banderali, G., Banderali, A., Rovera, G. M., Ballardini, D., Bertoni, G., Gramezi, A., Ronchi, B., Baldi, A., Carruba, M., Lacirignola, M., Capone, R., Agostoni, C., Fargion, S., Mosca, F., Roggero, P., Giannì, M. L., Cosmi, V., Donegani, G., Leonardi, F., Mattivi, F., Viola, R., Ferreiro, M. S., Giannini, M., Poli, A., Marangoni, F., Fatati, G., Grandone, I., Di Lorenzo, N., Carbonelli, M. G., Foschi, D., Riccardi, G., Giacco, R., Trimarchi, F., Aroso, M., Corazza, G. R., Biolo, G., Brighenti, F., Casini, A., Giovannini, M., Riva, E., Elvira Verduci, Sirtori, C., Cicero, A., Racca, A., Sarpa, B., Nisoli, E., Sbraccia, P., Busetto, L., Muratori, F., Migliaccio, P., Piretta, L., Melchionda, N., Donini, L. M., Guberti, E., Alonzo, E., Giorgino, F., Laviola, L., Banni, S., Agodi, A., Frittitta, L., Rotella, C. M., Dicembrini, I., Barbaro, V., Morelli, L., Contaldo, F., Gnessi, L., Laviano, A., Muscaritoli, M., Pinto, A., Vania, A., Lorenzo, A., Di Renzo, L., Vettor, R., D Andrea, F., Battino, M., Melissano, M., Scaffidi, C., Archero, E., Vezzali, V., and Buzzavo, G.

9. [Obesity and Eating Disorders. Indications for the different levels of care. An Italian Expert Consensus Document].,Documento di Consensus. Obesità e Disturbi dell'Alimentazione Indicazioni per i diversi livelli di trattamento

Author

Donini, L. M., Cuzzolaro, M., Spera, G., Badiali, M., Basso, N., Bollea, M. R., Bosello, O., Brunani, A., Busetto, L., Cairella, G., Cannella, C., Capodaglio, P., Carbonelli, M. G., Castellaneta, E., Castra, R., Clini, E., Contaldo, F., Dalla Ragione, L., Dalle Grave, R., D Andrea, F., Del Balzo, V., Cristofaro, P., Di Flaviano, E., Fassino, S., Ferro, A. M., Forestieri, P., Franzoni, E., Gentile, M. G., Giustini, A., Jacoangeli, F., Lubrano, C., Lucchin, L., Manara, F., Marangi, G., Marcelli, M., Marchesini, G., Marri, G., Marrocco, W., Melchionda, N., Mezzani, B., Migliaccio, P., Muratori, F., Nizzoli, U., Ostuzzi, R., Panzolato, G., Pasanisi, F., Persichetti, P., Petroni, M. L., Pontieri, V., Prosperi, E., Renna, C., Rovera, G., Ferruccio Santini, Saraceni, V., Savina, C., Scuderi, N., Silecchia, G., Strollo, F., Todisco, P., Tubili, C., Ugolini, G., and Zamboni, M.

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