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Supplemental Material for Characteristics and clinical needs of young tertiary students attending a specialist mood disorders clinic by Kieran M O'Gorman, Lianne Schmaal, Aswin Ratheesh, Jennifer Jackson-Simpson, Sue M Cotton, Simon M Rice, George Habib, and Orania Tokatlidis in Australasian Psychiatry

Supplemental Material for Assessing Suicidal Ideation in Young People With Depression: Factor Structure of the Suicidal Ideation Questionnaire by Carl I. Moller, Paul B. Badcock, Sarah E. Hetrick, Simon Rice, Michael Berk, Olivia M. Dean, Andrew M. Chanen, Caroline. Gao, Christopher G. Davey and Sue M. Cotton in Journal of Death and Dying

Supplemental material, sj-docx-1-anp-10.1177_00048674221115644 for Personality traits as mediators of the relationship between childhood trauma and depression severity in bipolar disorder: A structural equation model by Anna L Wrobel, Samantha E Russell, Anuradhi Jayasinghe, Bianca E Kavanagh, Mojtaba Lotfaliany, Alyna Turner, Olivia M Dean, Sue M Cotton, Claudia Diaz-Byrd, Anastasia K Yocum, Elizabeth R Duval, Tobin J Ehrlich, David F Marshall, Michael Berk and Melvin G McInnis in Australian & New Zealand Journal of Psychiatry

[Objective] The influence of childhood trauma on the treatment outcomes of pharmacological and/or psychological interventions for adolescents and adults with bipolar disorder was systematically reviewed. [Methods] Randomised and non-randomised studies of interventions for bipolar disorder that included an assessment of childhood trauma were eligible. MEDLINE Complete, Embase, PsycINFO, and the Cochrane Central Register of Controlled Trials were searched. Two independent reviewers completed the screening and extraction process. Two independent reviewers assessed the risk of bias in the included studies using the Cochrane Collaboration's Risk of Bias tool and the Newcastle-Ottawa Scale. Alongside a narrative synthesis, random-effects meta-analyses were performed. [Results] Twelve studies (1175 participants) were included. The narrative review highlighted differential treatment outcomes among individuals with a history of childhood trauma. The meta-analyses suggested that childhood trauma was unrelated to treatment response (five studies, 426 participants; odds ratio 0.58, 95% CI 0.27–1.25, p = .164) but may be associated with greater improvement in global functioning (three studies, 210 participants; Hedge's g 0.65, 95% CI 0.04–1.26, p = .037). [Limitations] The impact of childhood trauma on the effectiveness of specific pharmacological/psychological interventions could not be explored due to the small body of research identified. [Conclusion] The overall quality of the extant evidence is low, which precludes definitive comment on the role of childhood trauma in the treatment of bipolar disorder. Additional research that uses large and representative samples is required to ascertain whether a history of childhood trauma affects the treatment outcomes of interventions for individuals with bipolar disorder. ALW is supported by a Deakin University Centre of Research Excellence in Psychiatric Treatment Postgraduate Research Scholarship. AJ is supported by a Deakin University Research Training Program Scholarship. SER is supported by an Australian Government Research Training Program Scholarship. WM is currently funded by an Alfred Deakin Postdoctoral Research Fellowship and a Multiple Sclerosis Research Australia early-career fellowship. OMD is supported by a NHMRC R.D. Wright Biomedical Career Development Fellowship (APP1145634). SMC is supported by a NHMRC Senior Research Fellowship (APP1136344). MB is supported by a NHMRC Senior Principal Research Fellowship (APP1156072).

Supplemental Material, MITO-NAC_Physical_activity_Supplementary_Material for Physical Activity as a Predictor of Clinical Trial Outcomes in Bipolar Depression: A Subanalysis of a Mitochondrial-Enhancing Nutraceutical Randomized Controlled Trial by Melanie M. Ashton, Mohammadreza Mohebbi, Alyna Turner, Wolfgang Marx, Michael Berk, Gin S. Malhi, Chee H. Ng, Sue M. Cotton, Seetal Dodd, Jerome Sarris, Malcolm Hopwood, Brendon Stubbs and Olivia M. Dean in The Canadian Journal of Psychiatry

Supplemental material, Supplementary_file_2-4 for Diet quality, dietary inflammatory index and body mass index as predictors of response to adjunctive N-acetylcysteine and mitochondrial agents in adults with bipolar disorder: A sub-study of a randomised placebo-controlled trial by Melanie M Ashton, Olivia M Dean, Wolfgang Marx, Mohammadreza Mohebbi, Michael Berk, Gin S Malhi, Chee H Ng, Sue M Cotton, Seetal Dodd, Jerome Sarris, Malcolm Hopwood, Keshav Faye-Chauhan, Yesul Kim, Sarah R Dash, Felice N Jacka, Nitin Shivappa, James R Hebert and Alyna Turner in Australian & New Zealand Journal of Psychiatry

Supplemental Material, 19037-e-CJP-2019-134-OR.R1-__Abstract_for_translation-134 for Physical Activity as a Predictor of Clinical Trial Outcomes in Bipolar Depression: A Subanalysis of a Mitochondrial-Enhancing Nutraceutical Randomized Controlled Trial by Melanie M. Ashton, Mohammadreza Mohebbi, Alyna Turner, Wolfgang Marx, Michael Berk, Gin S. Malhi, Chee H. Ng, Sue M. Cotton, Seetal Dodd, Jerome Sarris, Malcolm Hopwood, Brendon Stubbs and Olivia M. Dean in The Canadian Journal of Psychiatry

Supplemental material, Supplementary_file_1 for Diet quality, dietary inflammatory index and body mass index as predictors of response to adjunctive N-acetylcysteine and mitochondrial agents in adults with bipolar disorder: A sub-study of a randomised placebo-controlled trial by Melanie M Ashton, Olivia M Dean, Wolfgang Marx, Mohammadreza Mohebbi, Michael Berk, Gin S Malhi, Chee H Ng, Sue M Cotton, Seetal Dodd, Jerome Sarris, Malcolm Hopwood, Keshav Faye-Chauhan, Yesul Kim, Sarah R Dash, Felice N Jacka, Nitin Shivappa, James R Hebert and Alyna Turner in Australian & New Zealand Journal of Psychiatry